Effect of medroxyprogesterone on development of pentylenetetrazole-induced kindling in mice

Neuroscience

Volumn 207, Issue , 2012, Pages 283-287

  Nasir, S A ^a   Sharma, A ^b   Khanam, R ^a   Vohora, D ^a  

^a HAMDARD UNIVERSITY   (India)

^b CSIR INSTITUTE OF GENOMICS AND INTEGRATIVE BIOLOGY   (India)

Author keywords

Diazepam; Grip strength; Medroxyprogesterone; Mifepristone; PTZ kindling; Spontaneous alternation behavior

Indexed keywords

DIAZEPAM; MEDROXYPROGESTERONE; MIFEPRISTONE; PENTETRAZOLE; PROGESTERONE; PROGESTERONE RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT THERAPY; ARTICLE; BEHAVIOR CHANGE; COGNITION; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFICACY; EPILEPTOGENESIS; FEMALE; GRIP STRENGTH; HORMONE ACTION; KINDLING; MALE; MAZE TEST; MOTOR PERFORMANCE; MOUSE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; SEIZURE; SEX RATIO; TREATMENT OUTCOME; TREATMENT RESPONSE;

ANIMALS; ANTICONVULSANTS; CONTRACEPTIVES, ORAL, SYNTHETIC; CONVULSANTS; DISEASE MODELS, ANIMAL; EPILEPSY; FEMALE; KINDLING, NEUROLOGIC; MALE; MEDROXYPROGESTERONE; MICE; PENTYLENETETRAZOLE; RECEPTORS, PROGESTERONE;

EID: 84863408602     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2012.01.031     Document Type: Article

References (39)

1. Acharya M.M., Hattiangady B., Shetty A.K. Progress in neuroprotective strategies for preventing epilepsy. Prog Neurobiol 2008, 84:363-404.
2. Ali A., Pillai K.K., Ahmad F.J., Dua Y., Vohora D. Evidence of the antiepileptic potential of amiloride with neuropharmacological benefits in rodent models of epilepsy and behaviour. Epilepsy Behav 2004, 5:322-328.
3. Ali A., Pillai K.K., Ahmad F.J., Dua Y., Vohora D. Anticonvulsant effect of amiloride in pentylenetetrazole-induced status epilepticus in mice. Pharmacol Rep 2006, 58:242-245.
4. Borowicz K.K., Kleinrok Z., Czuczwar S.J. Influence of sex hormone antagonists on the anticonvulsant action of conventional antiepileptic drugs against amygdala-kindled seizures in male and female rats. Eur Neuropsychopharmacol 2003, 13:257-265.
5. Borowicz K.K., Luszczki J., Matuszek M., Kleinrok Z., Czuczwar S.J. Effects of tamoxifen, mifepristone and cyproterone on the electroconvulsive threshold and pentylenetetrazole-induced convulsion in mice. Pol J Pharmacol 2002, 54:103-109.
6. Braden B.B., Talboom J.S., Crain I.D., Simard A.R., Lukas R.J., Prokai P., Scheldrup M.R., Bowman B.L., Bimonte-Nelson B.A. Medroxyprogesterone acetate impairs memory and alters the GABAergic system in aged surgically menopausal rats. Neurobiol Learn Mem 2010, 93:444-453.
7. Brinton R.D., Thompson R.F., Foy M.R., Baudry M., Wang J., Finch C.E., Morgan T.E., Pike C.J., Mack W.J., Stanczyk F.Z., Nilsen J. Progesterone receptors: form and function in brain. Front Neuroendocrinol 2008, 29:313-339.
8. Ciriza I., Carrero P., Frye C.A., Garcia-segura L.M. Reduced metabolites mediate neuroprotective effects of progesterone in the adult rat hippocampus. The synthetic progestin medroxyprogesterone acetate (Provera) is not neuroprotective. J Neurobiol 2006, 66:916-928.
9. Foldvary-Schaefer N., Harden C., Herzog A., Falcone T. Hormones and seizures. Cleve Clin J Med 2004, 71:S11-S18.
10. Freireich E.J., Gehan E.A., Rall D.P. Quantitative comparison of toxicity of anticancer agents in mouse, rat, hamster, dog, monkey and man. Cancer Chemother Rep 1966, 50:219-244.
11. Frye C.A. The neurosteroid 3c, 5c THP has anti seizure and possible neuroprotective effects in an animal model of epileptogenesis. Brain Res 1995, 696:113-120.
12. Frye C.A. Effects and mechanisms of progestogens and androgens in ictal activity. Epilepsia 2010, 51(3):135-140.
13. Frye C.A., Llaneza D.C., Walf A.A. Progesterone can enhance consolidation and/or performance in spatial, object and working memory tasks in Long-Evans rats. Anim Behav 2009, 78:279-286.
14. Frye C.A., Rhodes M.E., Walf A., Harney J. Progesterone reduces pentylenetetrazole-induced ictal activity of wild-type mice but not those deficient in type I 5α-reductase. Epilepsia 2002, 43:14-17.
15. Frye C.A., Scalise T.J. Anti-seizure effects of progesterone and 3α, 5α-THP in kainic acid and perforant pathway models of epilepsy. Psychoneuroendocrinology 2000, 25:407-420.
16. Frye C.A., Walf A.A. Effects of progesterone administration and APPswe + PSEN1De9 mutation for cognitive performance of mid-aged mice. Neurobiol Learn Mem 2008, 89:17-26.
17. Gallagher P., Watson S., Smith M.S., Ferrier I.N., Young A.H. Effects of adjunctive mifepristone (RU-486) administration on neurocognitive function and symptoms in schizophrenia. Biol Psychiatry 2005, 57:155-161.
18. Hammond G.L., Hirvonen J., Vihko R. Progesterone, androstenedione, testosterone, 5α-dihydrotestosterone and androsterone concentrations in specific regions of the human brain. J Steroid Biochem 1983, 18:185-189.
19. Itoh J., Nabeshima T., Kameyama T. Utility of an elevated plus-maze for dissociation of amnesic and behavioral effects of drugs in mice. Eur J Pharmacol 1991, 194:71-76.
20. Jacono J.J., Robertson J.M.D. The effects of estrogen, progesterone, and ionized calcium on seizures during the menstrual cycle of epileptic women. Epilepsia 1987, 28:571-577.
21. Lewis M.C., Orr P.T., Frick K.M. Differential effects of acute progesterone administration on spatial and object memory in middle-aged and aged female C57BL/6 mice. Horm Behav 2008, 54:455-462.
22. Lonsdale D., Burnham W.M. The anticonvulsant effects of progesterone and 5α-dihydroprogesterone on amygdala-kindled seizures in rats. Epilepsia 2003, 44:1494-1499.
23. Lonsdale D., Burnham W.M. The anticonvulsant effects of allopregnanolone against amygdala-kindled seizures in female rats. Neurosci Lett 2007, 411:147-151.
24. Mao R.R., Tian M., Yue-Xiong Y.X., Qi-Xin Z., Lin X., Jun C. Effects of pentylenetetrazol-induced brief convulsive seizures on spatial memory and fear memory. Epilepsy Behav 2009, 15:441-444.
25. Mattson R.H., Cramer J.A., Caldwell B.V., Siconolfi B.C. Treatment of seizures with medroxyprogesterone acetate: preliminary report. Neurology 1984, 34:1255-1258.
26. McAuley J.W., Kroboth P.D., Stiff D.D., Reynolds I.J. Modulation of [3H] flunitrazepam binding by natural and synthetic progestational agents. Pharmacol Biochem Behav 1993, 45:77-83.
27. Mesripour A., Hajhashemi V., Rabbani M. Metyrapone and mifepristone reverse memory loss induced by spontaneous morphine withdrawal in mice. Eur Psychiatry 2008, 23(Suppl 2):S292.
28. Mohammad S., Abolhassan A., Pourgholami M.H. Evaluation of the anticonvulsant profile of progesterone in male amygdala-kindled rats. Epilepsy Res 1998, 30:195-202.
29. Murialdo G., Magri F., Tamagno G., Ameri P., Camera A., Colnaghi S., Perucca P., Ravera G., Galimberti C.A. Seizure frequency and sex steroids in women with partial epilepsy on antiepileptic therapy. Epilepsia 2009, 50:1920-1926.
30. Nicoletti F., Speciale C., Sortino M.A., Summa G., Caruso G., Patti F., Canonico P.L. Comparative effects of estradiol benzoate, the antiestrogen clomiphene citrate, and the progestin medroxyprogesterone acetate on kainic acid-induced seizures in male and female rats. Epilepsia 1985, 26:252-257.
31. Nilsen J., Brinton R.D. Divergent impact of progesterone and medroxyprogesterone acetate (Provera) on nuclear mitogen-activated protein kinase signaling. Proc Natl Acad Sci U S A 2003, 100:10506-10511.
32. Omrani A., Ghadami M.R., Fathi N., Tahmasian M., Fathollahi Y., Touhidi A. Naloxone improves impairment of spatial performance induced by pentylenetetrazol kindling in rats. Neuroscience 2007, 145:824-831.
33. Ragozzino M.E., Pal S.N., Unick K., Stefani M.R., Gold P.E. Modulation of hippocampal acetylcholine release and spontaneous alternation scores by intrahippocampal glucose injections. J Neurosci 1998, 18:1595-1601.
34. Reddy D.S. Pharmacotherapy of catamenial epilepsy. Indian J Pharmacol 2005, 37:288-293.
35. Reddy D.S., Gangisetty O., Briyal S. Disease-modifying activity of progesterone in the hippocampus kindling model of epileptogenesis. Neuropharmacology 2010, 59:573-581.
36. Singh S., Hota D., Prakash A., Khanduja K.L., Arora S.K., Chakrabarti A. Allopregnanolone, the active metabolite of progesterone protects against neuronal damage in picrotoxin-induced seizure model in mice. Pharmacol Biochem Behav 2010, 94:416-422.
37. Vohora D., Pal S.N., Pillai K.K. Modulation of spontaneous alternation behavior of mice treated with thioperamide and tacrine in a cross maze task. Fundam Clin Pharmacol 2005, 19:531-532.
38. White H.S., Woodhead J.H., Franklin M.R., Swinyard E.A., Wolf H.A. General principles, experimental selection, quantification, and evaluation of antiepileptic drugs. Antiepilep. Drugs 1995, 4:99-110.
39. Zimmerman A.W., Holden K.R., Reiter E.O., Dekaban A.S. Medroxyprogesterone acetate in the treatment of seizures associated with menstruation. J Paediatr 1973, 83:959-963.