Preparation, characterization and pharmacokinetics of enrofloxacin-loaded solid lipid nanoparticles: Influences of fatty acids

Colloids and Surfaces B: Biointerfaces

Volumn 83, Issue 2, 2011, Pages 382-387

  Xie, Shuyu ^a   Zhu, Luyan ^a   Dong, Zhao ^a   Wang, Xiaofang ^a   Wang, Yan ^a   Li, Xihe ^b   Zhou, WenZhong ^a  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

^b Mengniu Dary R and D Center   (China)

Author keywords

Enrofloxacin; Fatty acids; Pharmacokinetics; Solid lipid nanoparticles

Indexed keywords

ANTI-BACTERIAL ACTIVITY; ENCAPSULATION EFFICIENCY; ENROFLOXACIN; IN-VITRO; INTRAMUSCULAR ADMINISTRATION; LARGER PARTICLE SIZES; LIPID MATRIX; LOADING CAPACITIES; MEAN RESIDENCE TIME; PALMITIC ACID; PHARMACOKINETIC STUDIES; POLYDISPERSITY INDICES; SIMILAR PATTERN; SINGLE-DOSE; SOLID LIPID NANOPARTICLES; SUSTAINED RELEASE; TETRADECANOIC ACID; ULTRA-SONICATION;

BIOCHEMISTRY; DRUG DOSAGE; ENCAPSULATION; HOMOGENIZATION METHOD; NANOPARTICLES; PHARMACOKINETICS; POLYDISPERSITY; STEARIC ACID; ZETA POTENTIAL;

DRUG PRODUCTS;

ENROFLOXACIN; MYRISTIC ACID; PALMITIC ACID; SOLID LIPID NANOPARTICLE; STEARIC ACID;

ANIMAL EXPERIMENT; ANTIBACTERIAL ACTIVITY; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DISPERSION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG HALF LIFE; IN VITRO STUDY; LIPID COMPOSITION; MALE; MEAN RESIDENCE TIME; MINIMUM INHIBITORY CONCENTRATION; MOUSE; NANOENCAPSULATION; NANOFABRICATION; NONHUMAN; PARTICLE SIZE; PHYSICAL CHEMISTRY; PLASMA CONCENTRATION-TIME CURVE; PRIORITY JOURNAL; SINGLE DRUG DOSE; STAPHYLOCOCCUS AUREUS; SUSTAINED RELEASE FORMULATION; ZETA POTENTIAL;

FATTY ACIDS; FLUOROQUINOLONES; LIPIDS; NANOPARTICLES; PARTICLE SIZE; SURFACE PROPERTIES;

MUS;

EID: 78651449676     PISSN: 09277765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2010.12.014     Document Type: Article

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