Selection of DNA aptamers against epidermal growth factor receptor with high affinity and specificity

Biochemical and Biophysical Research Communications

Volumn 453, Issue 4, 2014, Pages 681-685

  Wang, Deng Liang ^a   Song, Yan Ling ^b   Zhu, Zhi ^b   Li, Xi Lan ^b   Zou, Yuan ^b   Yang, Hai Tao ^a   Wang, Jiang Jie ^a   Yao, Pei Sen ^a   Pan, Ru Jun ^a   Yang, Chaoyong James ^b   Kang, De Zhi ^a  

^a FUJIAN MEDICAL UNIVERSITY   (China)

^b XIAMEN UNIVERSITY   (China)

Author keywords

Aptamer; DNA; EGFR; SELEX

Indexed keywords

APTAMER; DNA; EPIDERMAL GROWTH FACTOR RECEPTOR; TUTU22 APTAMER; UNCLASSIFIED DRUG; EGFR PROTEIN, HUMAN; PROTEIN BINDING;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DNA PROBE; DNA SEQUENCE; EXTRACELLULAR SPACE; FLOW CYTOMETRY; FLUORESCENCE; GLIOBLASTOMA CELL LINE; HUMAN; HUMAN CELL; JURKAT CELL LINE; PROTEIN DNA BINDING; PROTEIN DOMAIN; BINDING SITE; CHEMISTRY; EXPERIMENTAL NEOPLASM; GENETICS; METABOLISM; MOLECULAR GENETICS; MOLECULAR IMAGING; MOLECULARLY TARGETED THERAPY; NUCLEOTIDE SEQUENCE; PATHOLOGY; PATHOPHYSIOLOGY; PROCEDURES; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; TUMOR CELL LINE;

APTAMERS, NUCLEOTIDE; BASE SEQUENCE; BINDING SITES; CELL LINE, TUMOR; HUMANS; JURKAT CELLS; MOLECULAR IMAGING; MOLECULAR SEQUENCE DATA; MOLECULAR TARGETED THERAPY; NEOPLASMS, EXPERIMENTAL; PROTEIN BINDING; RECEPTOR, EPIDERMAL GROWTH FACTOR; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 84910006907     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.09.023     Document Type: Article

References (34)

1. F.G. Barker 2nd, M.L. Simmons, S.M. Chang, M.D. Prados, D.A. Larson, P.K. Sneed, W.M. Wara, M.S. Berger, P. Chen, M.A. Israel, and K.D. Aldape EGFR overexpression and radiation response in glioblastoma multiforme Int. J. Radiat. Oncol. Biol. Phys. 51 2001 410 418
2. M. Cardo-Vila, R.J. Giordano, R.L. Sidman, L.F. Bronk, Z. Fan, J. Mendelsohn, W. Arap, and R. Pasqualini From combinatorial peptide selection to drug prototype (II): targeting the epidermal growth factor receptor pathway Proc. Natl. Acad. Sci. U.S.A. 107 2010 5118 5123
3. T. de La Motte Rouge, L. Galluzzi, K.A. Olaussen, Y. Zermati, E. Tasdemir, T. Robert, H. Ripoche, V. Lazar, P. Dessen, F. Harper, G. Pierron, G. Pinna, N. Araujo, A. Harel-Belan, J.P. Armand, T.W. Wong, J.C. Soria, and G. Kroemer A Novel epidermal growth factor receptor inhibitor promotes apoptosis in non-small cell lung cancer cells resistant to erlotinib Cancer Res. 67 2007 6253 6262
4. S. Li, K.R. Schmitz, P.D. Jeffrey, J.J. Wiltzius, P. Kussie, and K.M. Ferguson Structural basis for inhibition of the epidermal growth factor receptor by cetuximab Cancer Cell 7 2005 301 311
5. F. Kyle, and J. Spicer Targeted therapies in non-small cell lung cancer Cancer Imaging 8 2008 199 205
6. T.J. Kruser, and D.L. Wheeler Mechanisms of resistance to HER family targeting antibodies Exp. Cell Res. 316 2010 1083 1100
7. W. Pao, V.A. Miller, K.A. Politi, G.J. Riely, R. Somwar, M.F. Zakowski, M.G. Kris, and H. Varmus Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain PLoS Med. 2 2005 e73
8. D.L. Wheeler, S. Huang, T.J. Kruser, M.M. Nechrebecki, E.A. Armstrong, S. Benavente, V. Gondi, K.T. Hsu, and P.M. Harari Mechanisms of acquired resistance to cetuximab: role of HER (ErbB) family members Oncogene 27 2008 3944 3956
9. C. Tuerk, and L. Gold Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase Science 249 1990 505 510
10. A.D. Ellington, and J.W. Szostak In vitro selection of RNA molecules that bind specific ligands Nature 346 1990 818 822
11. D. Shangguan, Y. Li, Z. Tang, Z.C. Cao, H.W. Chen, P. Mallikaratchy, K. Sefah, C.J. Yang, and W. Tan Aptamers evolved from live cells as effective molecular probes for cancer study Proc. Natl. Acad. Sci. U.S.A. 103 2006 11838 11843
12. S.M. Shamah, J.M. Healy, and S.T. Cload Complex target SELEX Acc. Chem. Res. 41 2008 130 138
13. J. Mi, Y. Liu, Z.N. Rabbani, Z. Yang, J.H. Urban, B.A. Sullenger, and B.M. Clary In vivo selection of tumor-targeting RNA motifs Nat. Chem. Biol. 6 2010 22 24
14. X. Fang, and W. Tan Aptamers generated from cell-SELEX for molecular medicine: a chemical biology approach Acc. Chem. Res. 43 2010 48 57
15. K. Sefah, D. Shangguan, X. Xiong, M.B. O'Donoghue, and W. Tan Development of DNA aptamers using Cell-SELEX Nat. Protoc. 5 2010 1169 1185
16. J.L. Vinkenborg, N. Karnowski, and M. Famulok Aptamers for allosteric regulation Nat. Chem. Biol. 7 2011 519 527
17. L. Yang, X. Zhang, M. Ye, J. Jiang, R. Yang, T. Fu, Y. Chen, K. Wang, C. Liu, and W. Tan Aptamer-conjugated nanomaterials and their applications Adv. Drug Deliv. Rev. 63 2011 1361 1370
18. W. Tan, H. Wang, Y. Chen, X. Zhang, H. Zhu, C. Yang, R. Yang, and C. Liu Molecular aptamers for drug delivery Trends Biotechnol. 29 2011 634 640
19. L. Cerchia, and V. de Franciscis Targeting cancer cells with nucleic acid aptamers Trends Biotechnol. 28 2010 517 525
20. L. Cerchia, P.H. Giangrande, J.O. McNamara, and V. de Franciscis Cell-specific aptamers for targeted therapies Methods Mol. Biol. 535 2009 59 78
21. J. Zhou, and J.J. Rossi Aptamer-targeted cell-specific RNA interference Silence 1 2010 4
22. E.W. Ng, D.T. Shima, P. Calias, E.T. Cunningham Jr., D.R. Guyer, and A.P. Adamis Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease Nat. Rev. Drug Discov. 5 2006 123 132
23. N. Li, H.H. Nguyen, M. Byrom, and A.D. Ellington Inhibition of cell proliferation by an anti-EGFR aptamer PLoS One 6 2011 e20299
24. C.L. Esposito, D. Passaro, I. Longobardo, G. Condorelli, P. Marotta, A. Affuso, V. de Franciscis, and L. Cerchia A neutralizing RNA aptamer against EGFR causes selective apoptotic cell death PLoS One 6 2011 e24071
25. Y. Song, Z. Zhu, Y. An, W. Zhang, H. Zhang, D. Liu, C. Yu, W. Duan, and C.J. Yang Selection of DNA aptamers against epithelial cell adhesion molecule for cancer cell imaging and circulating tumor cell capture Anal. Chem. 85 2013 4141 4149
26. J. Hu, J. Wu, C. Li, L. Zhu, W.Y. Zhang, G. Kong, Z. Lu, and C.J. Yang A G-quadruplex aptamer inhibits the phosphatase activity of oncogenic protein Shp2 in vitro ChemBioChem 12 2011 424 430
27. J. Wu, C. Wang, X. Li, Y. Song, W. Wang, C. Li, J. Hu, Z. Zhu, J. Li, W. Zhang, Z. Lu, and C.J. Yang Identification, characterization and application of a G-quadruplex structured DNA aptamer against cancer biomarker protein anterior gradient homolog 2 PLoS One 7 2012 e46393
28. K. Tamura, J. Dudley, M. Nei, and S. Kumar MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0 Mol. Biol. Evol. 24 2007 1596 1599
29. A.M. Egloff, and J.R. Grandis Targeting epidermal growth factor receptor and SRC pathways in head and neck cancer Semin. Oncol. 35 2008 286 297
30. J.F. Flynn, C. Wong, and J.M. Wu Anti-EGFR therapy: mechanism and advances in clinical efficacy in breast cancer J. Oncol. 2009 2009 526963
31. C.S. Karapetis, S. Khambata-Ford, D.J. Jonker, C.J. O'Callaghan, D. Tu, N.C. Tebbutt, R.J. Simes, H. Chalchal, J.D. Shapiro, S. Robitaille, T.J. Price, L. Shepherd, H.J. Au, C. Langer, M.J. Moore, and J.R. Zalcberg K-ras mutations and benefit from cetuximab in advanced colorectal cancer N. Engl. J. Med. 359 2008 1757 1765
32. M. Ladanyi, and W. Pao Lung adenocarcinoma: guiding EGFR-targeted therapy and beyond Mod. Pathol. 21 Suppl. 2 2008 S16 22
33. S.X. Yang, R.M. Simon, A.R. Tan, D. Nguyen, and S.M. Swain Gene expression patterns and profile changes pre- and post-erlotinib treatment in patients with metastatic breast cancer Clin. Cancer Res. 11 2005 6226 6232
34. Y. Tan, Y.S. Shi, X.D. Wu, H.Y. Liang, Y.B. Gao, S.J. Li, X.M. Zhang, F. Wang, and T.M. Gao DNA aptamers that target human glioblastoma multiforme cells overexpressing epidermal growth factor receptor variant III in vitro Acta Pharmacol. Sin. 34 2013 1491 1498