Angiotensin II upregulates Kv1.5 expression through ROS-dependent transforming growth factor-beta1 and extracellular signal-regulated kinase 1/2 signalings in neonatal rat atrial myocytes

Biochemical and Biophysical Research Communications

Volumn 454, Issue 3, 2014, Pages 410-416

  Lu, Guihua ^a,b   Xu, Shuang ^a,b   Peng, Longyun ^a   Huang, Zhibin ^a   Wang, Yesong ^a   Gao, Xiuren ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b BEIJING HOSPITAL   (China)

Author keywords

Angiotensin II; Antioxidant; ERK1 2; Kv1.5; ROS; TGF 1

Indexed keywords

1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ACETYLCYSTEINE; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; ANGIOTENSIN RECEPTOR ANTAGONIST; ANTIOXIDANT; DIPHENYLIODONIUM SALT; LOSARTAN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; POSTSYNAPTIC DENSITY PROTEIN 95; POTASSIUM CHANNEL KV1.5; PROTEIN; REACTIVE OXYGEN METABOLITE; SMAD2 PROTEIN; SMAD3 PROTEIN; SMALL INTERFERING RNA; SYNAPSE ASSOCIATED PROTEIN 97; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; DLGH1 PROTEIN, RAT; MADH2 PROTEIN, RAT; MADH3 PROTEIN, RAT; MEMBRANE PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONCENTRATION (PARAMETERS); FLOW CYTOMETRY; HEART ATRIUM; MUSCLE CELL; NEWBORN; NEWBORN PERIOD; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SYNAPSE; UPREGULATION; WESTERN BLOTTING; ANIMAL; CARDIAC MUSCLE CELL; CELL CULTURE; CYTOLOGY; GENETICS; MAPK SIGNALING; METABOLISM; SPRAGUE DAWLEY RAT;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANGIOTENSIN II; ANIMALS; CELLS, CULTURED; HEART ATRIA; KV1.5 POTASSIUM CHANNEL; MAP KINASE SIGNALING SYSTEM; MEMBRANE PROTEINS; MYOCYTES, CARDIAC; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RECEPTOR, ANGIOTENSIN, TYPE 1; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; UP-REGULATION;

EID: 84909986624     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.10.088     Document Type: Article

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