Genotyping and virological characteristics of hepatitis B virus in HIV-infected individuals in Sudan

International Journal of Infectious Diseases

Volumn 29, Issue , 2014, Pages e125-e132

  Yousif, Mukhlid ^a   Mudawi, Hatim ^b   Hussein, Waleed ^c   Mukhtar, Maowia ^c   Nemeri, Omer ^d   Glebe, Dieter ^e   Kramvis, Anna ^a  

^a UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^b UNIVERSITY OF KHARTOUM   (Sudan)

^c UNIVERSITY OF KHARTOUM   (Sudan)

^d UNIVERSITY OF BAHRI   (Sudan)

^e JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

Deletion mutants; Genetic diversity; Occult HBV infection; Subgenotypes

Indexed keywords

HEPATITIS B SURFACE ANTIGEN; HEPATITIS B(E) ANTIGEN; VIRUS DNA;

ADULT; ARTICLE; FEMALE; GENOTYPE; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; MAJOR CLINICAL STUDY; MALE; MIXED INFECTION; OCCULT HEPATITIS B; SEROLOGY; SUDAN; VIRUS HEPATITIS; VIRUS LOAD; VIRUS MUTATION; BLOOD; CLASSIFICATION; COMPLICATION; GENETICS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MIDDLE AGED; MUTATION; VIROLOGY; YOUNG ADULT;

ADULT; COINFECTION; FEMALE; GENOTYPE; HEPATITIS B; HEPATITIS B E ANTIGENS; HEPATITIS B VIRUS; HIV INFECTIONS; HUMANS; MALE; MIDDLE AGED; MUTATION; SUDAN; YOUNG ADULT;

EID: 84909644861     PISSN: 12019712     EISSN: 18783511     Source Type: Journal    
DOI: 10.1016/j.ijid.2014.07.002     Document Type: Article

References (54)

1. Vogt V. Retroviral virions and genomes 1997, Cold Spring Harbor Laboratory Press, Cold Spring Harbor (NY).
2. Alter M.J. Epidemiology of viral hepatitis and HIV co-infection. J Hepatol 2006, 44:S6.
3. Mahgoub S., Candotti D., El Ekiaby M., Allain J.P. Hepatitis B virus (HBV) infection and recombination between HBV genotypes D and E in asymptomatic blood donors from Khartoum, Sudan. J Clin Microbiol 2011, 49:298-306.
4. McCarthy M.C., el-Tigani A., Khalid I.O., Hyams K.C. Hepatitis B and C in Juba, southern Sudan: results of a serosurvey. Trans R Soc Trop Med Hyg 1994, 88:534-536.
5. UNAIDS. 2008 Report on the global AIDS epidemic. World Health Organization; 2008.
6. Sudan National AIDS Control Programme Global AIDS response progress reporting 2010-2011 2012, National Ministry of Health, Sudan.
7. McCarthy M.C., Burans J.P., Constantine N.T., El-Hag A.A., El-Tayeb M.E., El-Dabi M.A., et al. Hepatitis B and HIV in Sudan: a Serosurvey for Hepatitis B and Human Immunodeficiency Virus Antibodies among Sexually Active Heterosexuals. Am J Trop Med Hyg 1989, 41:726-731.
8. McCarthy M.C., Hyams K.C., El-Hag A.E., El-Dabi M.A., El-Tayeb M.E., Khalid I.O., et al. HIV-1 and hepatitis B transmission in Sudan. AIDS 1989, 3:725-730.
9. Mudawi H, Hussein W, Mukhtar M, Yousif M, Nemeri O, Glebe D, Kramvis A. Overt and occult hepatitis B virus infection in adult Sudanese HIV patients. Int J Infect Dis 2014, in press.
10. Raimondo G., Allain J.P., Brunetto M.R., Buendia M.A., Chen D.S., Colombo M., et al. Statements from the Taormina expert meeting on occult hepatitis B virus infection. J Hepatol 2008, 49:652-657.
11. Bell T.G., Makondo E., Martinson N.A., Kramvis A., Hepatitis B. virus infection in human immunodeficiency virus infected Southern African adults: occult or overt-that is the question. PLoS One 2012, 7:e45750.
12. Okamoto H., Tsuda F., Sakugawa H., Sastrosoewignjo R.I., Imai M., Miyakawa Y., et al. Typing hepatitis B virus by homology in nucleotide sequence: comparison of surface antigen subtypes. J Gen Virol 1988, 69:2575-2583.
13. Naumann H., Schaefer S., Yoshida C.F., Gaspar A.M., Repp R., Gerlich W.H. Identification of a new hepatitis B virus (HBV) genotype from Brazil that expresses HBV surface antigen subtype adw4. J Gen Virol 1993, 74(Pt 8):1627-1632.
14. Norder H., Courouce A.M., Magnius L.O. Complete genomes, phylogenetic relatedness, and structural proteins of six strains of the hepatitis B virus, four of which represent two new genotypes. Virology 1994, 198:489-503.
15. Norder H., Hammas B., Lofdahl S., Courouce A.M., Magnius L.O. Comparison of the amino acid sequences of nine different serotypes of hepatitis B surface antigen and genomic classification of the corresponding hepatitis B virus strains. J Gen Virol 1992, 73(Pt 5):1201-1208.
16. Stuyver L., De Gendt S., Van Geyt C., Zoulim F., Fried M., Schinazi R.F., et al. A new genotype of hepatitis B virus: complete genome and phylogenetic relatedness. J Gen Virol 2000, 81:67-74.
17. Arauz-Ruiz P., Norder H., Robertson B.H., Magnius L.O. Genotype H: a new Amerindian genotype of hepatitis B virus revealed in Central America. J Gen Virol 2002, 83:2059-2073.
18. Yu H., Yuan Q., Ge S.X., Wang H.Y., Zhang Y.L., Chen Q.R., et al. Molecular and phylogenetic analyses suggest an additional hepatitis B virus genotype "I". PLoS One 2010, 5:e9297.
19. Tatematsu K., Tanaka Y., Kurbanov F., Sugauchi F., Mano S., Maeshiro T., et al. A genetic variant of hepatitis B virus divergent from known human and ape genotypes isolated from a Japanese patient and provisionally assigned to new genotype J. J Virol 2009, 83:10538-10547.
20. Kramvis A., Arakawa K., Yu M.C., Nogueira R., Stram D.O., Kew M.C. Relationship of serological subtype, basic core promoter and precore mutations to genotypes/subgenotypes of hepatitis B virus. J Med Virol 2008, 80:27-46.
21. Norder H., Courouce A.M., Magnius L.O. Molecular basis of hepatitis B virus serotype variations within the four major subtypes. J Gen Virol 1992, 73(Pt 12):3141-3145.
22. Kramvis A., Kew M., Francois G. Hepatitis B virus genotypes. Vaccine 2005, 23:2409-2423.
23. Kramvis A., Kew M.C. Relationship of genotypes of hepatitis B virus to mutations, disease progression and response to antiviral therapy. J Viral Hepat 2005, 12:456-464.
24. Kao J.H., Chen P.J., Lai M.Y., Chen D.S. Genotypes and clinical phenotypes of hepatitis B virus in patients with chronic hepatitis B virus infection. J Clin Microbiol 2002, 40:1207-1209.
25. McMahon B.J. The influence of hepatitis B virus genotype and subgenotype on the natural history of chronic hepatitis B. Hepatol Int 2009, 3:334-342.
26. Yousif M., Mudawi H., Bakhiet S., Glebe D., Kramvis A. Molecular characterization of hepatitis B virus in liver disease patients and asymptomatic carriers of the virus in Sudan. BMC Infect Dis 2013, 13:328.
27. Takahashi K., Aoyama K., Ohno N., Iwata K., Akahane Y., Baba K., et al. The precore/core promoter mutant (T1762A1764) of hepatitis B virus: clinical significance and an easy method for detection. J Gen Virol 1995, 76(Pt 12):3159-3164.
28. Vermeulen M., Dickens C., Lelie N., Walker E., Coleman C., Keyter M., et al. virus transmission by blood transfusion during 4 years of individual-donation nucleic acid testing in South Africa: estimated and observed window period risk. Transfusion 2012, 52:880-892.
29. Bell T.G., Kramvis A. Fragment Merger: an online tool to merge overlapping long sequence fragments. Viruses 2013, 5:824-833.
30. Yousif M., Kramvis A. Genotype D of hepatitis B virus and its subgenotypes: an update. Hepatol Res 2013, 43:355-364.
31. Gulube Z., Chirara M., Kew M., Tanaka Y., Mizokami M., Kramvis A. Molecular characterization of hepatitis B virus isolates from Zimbabwean blood donors. J Med Virol 2011, 83:235-244.
32. Page R.D. TreeView: an application to display phylogenetic trees on personal computers. Comput Appl Biosci 1996, 12:357-358.
33. Papatheodoridis G.V., Manolakopoulos S., Liaw Y.F., Lok A. Follow-up and indications for liver biopsy in HBeAg-negative chronic hepatitis B virus infection with persistently normal ALT: a systematic review. J Hepatol 2012, 57:196-202.
34. Kramvis A., Kew M.C. Molecular characterization of subgenotype A1 (subgroup Aa) of hepatitis B virus. Hepatol Res 2007, 37:S27-S32.
35. Kramvis A., Paraskevis D. Subgenotype A1 of HBV-tracing human migrations in and out of Africa. Antivir Ther 2012, 18:513-521.
36. Hübschen J.M., Mugabo J., Peltier C.A., Karasi J.C., Sausy A., Kirpach P., et al. Exceptional genetic variability of hepatitis B virus indicates that Rwanda is east of an emerging African genotype E/A1 divide. J Med Virol 2009, 81:435-440.
37. Kramvis A., Restorp K., Norder H., Botha J.F., Magnius L.O., Kew M.C. Full genome analysis of hepatitis B virus genotype E strains from South-Western Africa and Madagascar reveals low genetic variability. J Med Virol 2005, 77:47-52.
38. Norder H., Courouce A.M., Coursaget P., Echevarria J.M., Lee S.D., Mushahwar I.K., et al. Genetic diversity of hepatitis B virus strains derived worldwide: genotypes, subgenotypes, and HBsAg subtypes. Intervirology 2004, 47:289-309.
39. Pal A., Panigrahi R., Biswas A., Datta S., Sarkar N., Guha S.K., et al. Influence of HIV-associated degree of immune suppression on molecular heterogeneity of hepatitis B virus among HIV co-infected patients. Virology 2013, 436:134-142.
40. Buckwold V.E., Xu Z., Chen M., Yen T.S., Ou J.H. Effects of a naturally occurring mutation in the hepatitis B virus basal core promoter on precore gene expression and viral replication. J Virol 1996, 70:5845-5851.
41. Garmiri P., Loua A., Haba N., Candotti D., Allain J.P. Deletions and recombinations in the core region of hepatitis B virus genotype E strains from asymptomatic blood donors in Guinea. West Africa. J Gen Virol 2009, 90:2442-2451.
42. Chen B.F., Liu C.J., Jow G.M., Chen P.J., Kao J.H., Chen D.S. High prevalence and mapping of Pre-S deletion in hepatitis B virus carriers with progressive liver diseases. Gastroenterology 2006, 130:1153-1168.
43. Kew M.C., Kramvis A., Yu M.C., Arakawa K., Hodkinson J. Increased hepatocarcinogenic potential of hepatitis B virus genotype A in Bantu-speaking Sub-Saharan Africans. J Med Virol 2005, 75:513-521.
44. Makondo E., Bell T.G., Kramvis A. Genotyping and molecular characterization of hepatitis B virus from human immunodeficiency virus-infected individuals in Southern Africa. PLoS One 2012, 7:e46345.
45. Audsley J., Littlejohn M., Yuen L., Sasadeusz J., Ayres A., Desmond C., et al. HBV mutations in untreated HIV-HBV co-infection using genomic length sequencing. Virology 2010, 405:539-547.
46. Biswas A., Panigrahi R., Banerjee A., Pal M., De B.K., Chakrabarti S., et al. Differential pattern of pre-S mutations/deletions and its association with hepatitis B virus genotypes in Eastern India. Infect Genet Evol 2012, 12:384-391.
47. Mun H.S., Lee S.A., Kim H., Hwang E.S., Kook Y.H., Kim B.J. Novel F141L pre-S2 mutation in hepatitis B virus increases the risk of hepatocellular carcinoma in patients with chronic genotype C infections. J Virol 2011, 85:123-132.
48. Gopalakrishnan D., Keyter M., Shenoy K., Balakumaran L., Barathi T., Thomas V., et al. Predominance of subgenotype A1 of hepatitis B virus in liver disease patients from the state of Kerala, Southern India. World J Gastroenterol 2013, 19:9294-9306.
49. Kew M.C., Smuts H., Stewart A. Does HIV infection enhance the hepatocarcinogenic potential of chronic hepatitis B virus infection?. J Acquir Immune Defic Syndr 2010, 53:413-414.
50. Mphahlele M.J., Lukhwareni A., Burnett R.J., Moropeng L.M., Ngobeni J.M. High risk of occult hepatitis B virus infection in HIV-positive patients from South Africa. J Clin Virol 2006, 35:14-20.
51. Henke-Gendo C., Amini-Bavil-Olyaee S., Challapalli D., Trautwein C., Deppe H., Schulz T.F., et al. Symptomatic hepatitis B virus (HBV) reactivation despite reduced viral fitness is associated with HBV test and immune escape mutations in an HIV-coinfected patient. J Infect Dis 2008, 198:1620-1624.
52. Quarleri J., Moretti F., Bouzas M., Laufer N., Carrillo M.G., Giuliano S.F., et al. Hepatitis B virus genotype distribution and its lamivudine-resistant mutants in HIV-coinfected patients with chronic and occult hepatitis B. AIDS Res Hum Retroviruses 2007, 23:525-531.
53. Ochwoto M., Chauhan R., Goplakrishnan D., Chen C.Y., Ng'ang'a Z., Okoth F., et al. Genotyping and molecular characterization of hepatitis B virus in liver disease patients in Kenya. Infect Genet Evol 2013, 20:103-110.
54. Forbi J.C., Ben-Ayed Y., Xia G., Vaughan G., Drobeniuc J., Switzer W.M., et al. Disparate distribution of hepatitis B virus genotypes in four Sub-Saharan African countries. J Clin Virol 2013, 58:59-66.