New approaches to the treatment of biofilm-related infections

Journal of Infection

Volumn 69, Issue S1, 2014, Pages S47-S52

  Wilkins, Matthew ^a,b   Hall Stoodley, Luanne ^b,c   Allan, Raymond N ^a,b   Faust, Saul N ^a,b  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b UNIVERSITY HOSPITAL SOUTHAMPTON NHS FOUNDATION TRUST   (United Kingdom)

^c OHIO STATE UNIVERSITY   (United States)

Author keywords

Bacterial infection; Clinical biofilm infection; Diagnosis; Pathophysiology; Treatment

Indexed keywords

ANTIBIOTIC AGENT; TOBRAMYCIN; ANTIINFECTIVE AGENT;

ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL INFECTION; BACTERIAL METABOLISM; BACTERIUM ADHERENCE; BACTERIUM CONTAMINATION; BIOFILM; BIOFILM ASSOCIATED INFECTION; CHRONIC OTITIS MEDIA; CHRONIC WOUND; CONFOCAL LASER MICROSCOPY; CYSTIC FIBROSIS; DEBRIDEMENT; DEVICE INFECTION; DEVICE REMOVAL; DRUG EFFICACY; DRUG TOLERANCE; EXTRACELLULAR MATRIX; FLUORESCENCE IN SITU HYBRIDIZATION; GENETIC REGULATION; HUMAN; IMMUNE RESPONSE; INFLAMMATION; MICROBIAL COMMUNITY; MICROBIAL DIVERSITY; NONHUMAN; PATHOGENESIS; PHAGOCYTOSIS; POLYMERASE CHAIN REACTION; PUBLIC HEALTH; QUORUM SENSING; ANTIBIOTIC RESISTANCE; BACTERIAL INFECTIONS; BACTERIAL PHENOMENA AND FUNCTIONS; DRUG EFFECTS; GROWTH, DEVELOPMENT AND AGING; MICROBIOLOGY;

ANTI-BACTERIAL AGENTS; BACTERIAL INFECTIONS; BACTERIAL PHYSIOLOGICAL PHENOMENA; BIOFILMS; DRUG RESISTANCE, BACTERIAL; HUMANS;

EID: 84909639828     PISSN: 01634453     EISSN: 15322742     Source Type: Journal    
DOI: 10.1016/j.jinf.2014.07.014     Document Type: Article

References (56)

1. Costerton J.W., Geesey G.G., Cheng K.J. How bacteria stick. Sci Am 1978, 238(1):86-95.
2. Hall-Stoodley L., Stoodley P. Biofilm formation and dispersal and the transmission of human pathogens. Trends Microbiol 2005, 13(1):7-10.
3. Donlan R.M., Costerton J.W. Biofilms: survival mechanisms of clinically relevant microorganisms. Clin Microbiol Rev 2002, 15(2):167-193.
4. Costerton J.W., Stewart P.S., Greenberg E.P. Bacterial biofilms: a common cause of persistent infections. Science 1999, 284(5418):1318-1322.
5. Flemming H.C., Wingender J. The biofilm matrix. Nat Rev Microbiol 2010, 8(9):623-633.
6. Costerton J.W., Irvin R.T., Cheng K.J. The bacterial glycocalyx in nature and disease. Annu Rev Microbiol 1981, 35:299-324.
7. Gilbert P., Das J., Foley I. Biofilm susceptibility to antimicrobials. Adv Dent Res 1997, 11(1):160-167.
8. Fux C.A., Costerton J.W., Stewart P.S., Stoodley P. Survival strategies of infectious biofilms. Trends Microbiol 2005, 13(1):34-40.
9. Foreman A., Holtappels G., Psaltis A.J., Jervis-Bardy J., Field J., Wormald P.J., et al. Adaptive immune responses in Staphylococcus aureus biofilm-associated chronic rhinosinusitis. Allergy 2011, 66(11):1449-1456.
10. Hall-Stoodley L., Hu F.Z., Gieseke A., Nistico L., Nguyen D., Hayes J., et al. Direct detection of bacterial biofilms on the middle-ear mucosa of children with chronic otitis media. JAm Med Assoc 2006, 296(2):202-211.
11. Kirketerp-Møller K., Jensen P., Fazli M., Madsen K.G., Pedersen J., Moser C., et al. Distribution, organization, and ecology of bacteria in chronic wounds. J Clin Microbiol 2008, 46(8):2717-2722.
12. Starner T.D., Zhang N., Kim G., Apicella M.A., McCray P.B. Haemophilus influenzae forms biofilms on airway epithelia: implications in cystic fibrosis. Am J Respir Crit Care Med 2006, 174(2):213-220.
13. Psaltis A.J., Ha K.R., Beule A.G., Tan L.W., Wormald P.J. Confocal scanning laser microscopy evidence of biofilms in patients with chronic rhinosinusitis. Laryngoscope 2007, 117(7):1302-1306.
14. Potera C. Forging a link between biofilms and disease. Science 1999, 283(5409). 1837, 1839.
15. Jesaitis A.J., Franklin M.J., Berglund D., Sasaki M., Lord C.I., Bleazard J.B., et al. Compromised host defense on Pseudomonas aeruginosa biofilms: characterization of neutrophil and biofilm interactions. J Immunol 2003, 171(8):4329-4339.
16. Fuqua W.C., Winans S.C., Greenberg E.P. Quorum sensing in bacteria: the LuxR-LuxI family of cell density-responsive transcriptional regulators. J Bacteriol 1994, 176(2):269-275.
17. Donlan R.M. Biofilms: microbial life on surfaces. Emerg Infect Dis 2002, 8(9):881-890.
18. Whiteley M., Bangera M.G., Bumgarner R.E., Parsek M.R., Teitzel G.M., Lory S., et al. Gene expression in Pseudomonas aeruginosa biofilms. Nature 2001, 413(6858):860-864.
19. Schoolnik G.K., Voskuil M.I., Schnappinger D., Yildiz F.H., Meibom K., Dolganov N.A., et al. Whole genome DNA microarray expression analysis of biofilm development by Vibrio cholerae O1 E1 Tor. Methods Enzymol 2001, 336:3-18.
20. Schembri M.A., Kjaergaard K., Klemm P. Global gene expression in Escherichia coli biofilms. Mol Microbiol 2003, 48(1):253-267.
21. Beenken K.E., Dunman P.M., McAleese F., Macapagal D., Murphy E., Projan S.J., et al. Global gene expression in Staphylococcus aureus biofilms. J Bacteriol 2004, 186(14):4665-4684.
22. Beloin C., Ghigo J.M. Finding gene-expression patterns in bacterial biofilms. Trends Microbiol 2005, 13(1):16-19.
23. Sutherland I. Biofilm exopolysaccharides: a strong and sticky framework. Microbiology 2001, 147(Pt 1):3-9.
24. Leriche V., Sibille P., Carpentier B. Use of an enzyme-linked lectin sorbent assay to monitor the shift in polysaccharide composition in bacterial biofilms. Appl Environ Microbiol 2000, 66(5):1851-1856.
25. Costerton W., Veeh R., Shirtliff M., Pasmore M., Post C., Ehrlich G. The application of biofilm science to the study and control of chronic bacterial infections. J Clin Invest 2003, 112(10):1466-1477.
26. Costerton J.W., Lewandowski Z., Caldwell D.E., Korber D.R., Lappin-Scott H.M. Microbial biofilms. Annu Rev Microbiol 1995, 49:711-745.
27. Allison D.G., Ruiz B., SanJose C., Jaspe A., Gilbert P. Extracellular products as mediators of the formation and detachment of Pseudomonas fluorescens biofilms. FEMS Microbiol Lett 1998, 167(2):179-184.
28. Hall-Stoodley L., Costerton J.W., Stoodley P. Bacterial biofilms: from the natural environment to infectious diseases. Nat Rev Microbiol 2004, 2(2):95-108.
29. Stoodley P., Wilson S., Hall-Stoodley L., Boyle J.D., Lappin-Scott H.M., Costerton J.W. Growth and detachment of cell clusters from mature mixed-species biofilms. Appl Environ Microbiol 2001, 67(12):5608-5613.
30. Lowy F.D. Staphylococcus aureus infections. N Engl J Med 1998, 339(8):520-532.
31. Boyd A., Chakrabarty A.M. Role of alginate lyase in cell detachment of Pseudomonas aeruginosa. Appl Environ Microbiol 1994, 60(7):2355-2359.
32. Lee S.F., Li Y.H., Bowden G.H. Detachment of Streptococcus mutans biofilm cells by an endogenous enzymatic activity. Infect Immun 1996, 64(3):1035-1038.
33. Staudinger B.J., Muller J.F., Halldórsson S., Boles B., Angermeyer A., Nguyen D., et al. Conditions associated with the cystic fibrosis defect promote chronic Pseudomonas aeruginosa infection. Am J Respir Crit Care Med 2014, 189(7):812-824.
34. Møller S., Sternberg C., Andersen J.B., Christensen B.B., Ramos J.L., Givskov M., et al. In situ gene expression in mixed-culture biofilms: evidence of metabolic interactions between community members. Appl Environ Microbiol 1998, 64(2):721-732.
35. Bryant M.P., Wolin E.A., Wolin M.J., Wolfe R.S. Methanobacillus omelianskii, a symbiotic association of two species of bacteria. Arch Mikrobiol 1967, 59(1):20-31.
36. Stewart P.S., Costerton J.W. Antibiotic resistance of bacteria in biofilms. Lancet 2001, 358(9276):135-138.
37. Fux C.A., Stoodley P., Hall-Stoodley L., Costerton J.W. Bacterial biofilms: a diagnostic and therapeutic challenge. Expert Rev Anti Infect Ther 2003, 1(4):667-683.
38. Hoyle B.D., Wong C.K., Costerton J.W. Disparate efficacy of tobramycin on Ca(2+)-, Mg(2+)-, and HEPES-treated Pseudomonas aeruginosa biofilms. Can J Microbiol 1992, 38(11):1214-1218.
39. Giwercman B., Jensen E.T., Høiby N., Kharazmi A., Costerton J.W. Induction of beta-lactamase production in Pseudomonas aeruginosa biofilm. Antimicrobial Agents Chemother 1991, 35(5):1008-1010.
40. Maira-Litrán T., Allison D.G., Gilbert P. An evaluation of the potential of the multiple antibiotic resistance operon (mar) and the multidrug efflux pump acrAB to moderate resistance towards ciprofloxacin in Escherichia coli biofilms. J Antimicrob Chemother 2000, 45(6):789-795.
41. Borriello G., Werner E., Roe F., Kim A.M., Ehrlich G.D., Stewart P.S. Oxygen limitation contributes to antibiotic tolerance of Pseudomonas aeruginosa in biofilms. Antimicrob Agents Chemother 2004, 48(7):2659-2664.
42. Anderl J.N., Zahller J., Roe F., Stewart P.S. Role of nutrient limitation and stationary-phase existence in Klebsiella pneumoniae biofilm resistance to ampicillin and ciprofloxacin. Antimicrob Agents Chemother 2003, 47(4):1251-1256.
43. Lewis K. Riddle of biofilm resistance. Antimicrob Agents Chemother 2001, 45(4):999-1007.
44. Dawson C.C., Intapa C., Jabra-Rizk M.A. "Persisters": survival at the cellular level. PLoS Pathog 2011, 7(7):e1002121.
45. Post J.C., Preston R.A., Aul J.J., Larkins-Pettigrew M., Rydquist-White J., Anderson K.W., et al. Molecular analysis of bacterial pathogens in otitis media with effusion. J Am Med Assoc 1995, 273(20):1598-1604.
46. Ecker D.J., Sampath R., Massire C., Blyn L.B., Hall T.A., Eshoo M.W., et al. Ibis T5000: a universal biosensor approach for microbiology. Nat Rev Microbiol 2008, 6(7):553-558.
47. Hall-Stoodley L., Stoodley P. Evolving concepts in biofilm infections. Cell Microbiol 2009, 11(7):1034-1043.
48. Hall-Stoodley L., Stoodley P., Kathju S., Høiby N., Moser C., Costerton J.W., et al. Towards diagnostic guidelines for biofilm-associated infections. FEMS Immunol Med Microbiol 2012, 65(2):127-145.
49. Høiby N., Bjarnsholt T., Givskov M., Molin S., Ciofu O. Antibiotic resistance of bacterial biofilms. Int J Antimicrob Agents 2010, 35(4):322-332.
50. Hentzer M., Wu H., Andersen J.B., Riedel K., Rasmussen T.B., Bagge N., et al. Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors. EMBO J 2003, 22(15):3803-3815.
51. Christensen L.D., van Gennip M., Jakobsen T.H., Alhede M., Hougen H.P., Høiby N., et al. Synergistic antibacterial efficacy of early combination treatment with tobramycin and quorum-sensing inhibitors against Pseudomonas aeruginosa in an intraperitoneal foreign-body infection mouse model. JAntimicrob Chemother 2012, 67(5):1198-1206.
52. Römling U., Galperin M.Y., Gomelsky M. Cyclic di-GMP: the first 25 years of a universal bacterial second messenger. Microbiol Mol Biol Rev 2013, 77(1):1-52.
53. Barraud N., Schleheck D., Klebensberger J., Webb J.S., Hassett D.J., Rice S.A., et al. Nitric oxide signaling in Pseudomonas aeruginosa biofilms mediates phosphodiesterase activity, decreased cyclic di-GMP levels, and enhanced dispersal. JBacteriol 2009, 191(23):7333-7342.
54. Barraud N., Hassett D.J., Hwang S.H., Rice S.A., Kjelleberg S., Webb J.S. Involvement of nitric oxide in biofilm dispersal of Pseudomonas aeruginosa. J Bacteriol 2006, 188(21):7344-7353.
55. Barraud N., Kardak B.G., Yepuri N.R., Howlin R.P., Webb J.S., Faust S.N., et al. Cephalosporin-3'-diazeniumdiolates: targeted NO-donor prodrugs for dispersing bacterial biofilms. Angew Chem Int Ed Engl 2012, 51(36):9057-9060.
56. Parsek M.R., Singh P.K. Bacterial biofilms: an emerging link to disease pathogenesis. Annu Rev Microbiol 2003, 57:677-701.