Ethnicity moderates dementia's biomarkers

Journal of Alzheimer's Disease

Volumn 43, Issue 1, 2014, Pages 275-287

  Royall, Donald R ^a,b   Palmer, Raymond F ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b SOUTH TEXAS VETERANS HEALTH CARE SYSTEM   (United States)

Author keywords

Aging; cognition; dementia; functional status; g; Hispanic

Indexed keywords

BIOLOGICAL MARKER;

AGED; ANALYSIS OF VARIANCE; BLOOD; CAUCASIAN; DEMENTIA; ETHNOLOGY; FEMALE; HUMAN; MALE; MEXICAN AMERICAN; MULTIVARIATE ANALYSIS; NEUROPSYCHOLOGICAL TEST; PSYCHOLOGY; RECEIVER OPERATING CHARACTERISTIC; STATISTICAL ANALYSIS;

AGED; ANALYSIS OF VARIANCE; BIOMARKERS; DATA INTERPRETATION, STATISTICAL; DEMENTIA; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; HUMANS; MALE; MEXICAN AMERICANS; MULTIVARIATE ANALYSIS; NEUROPSYCHOLOGICAL TESTS; ROC CURVE;

EID: 84908703581     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-140264     Document Type: Article

References (84)

1. Royall DR, Palmer RF, OBryant SE (2012) Validation of a latent variable representing the dementing process. J Alzheimers Dis 30, 639-649.
2. Spearman C,Wynn Jones LL (1951) Human Ability,Macmillan & Co., London.
3. Royall DR, Palmer RF (2013) Getting past "g": Testing a new model of dementing processes in non-demented persons. J Neuropsychiatr Clin Neurosci 24, 37-46.
4. Royall DR, Palmer RF (2013) Validation of a latent construct for dementia case-finding in Mexican-Americans. J Alzheimers Dis 37, 89-97.
5. Royall DR, Palmer RF (2014) Does ethnicity moderate dementias biomarkers? Neurobiol Aging 35, 336-344.
6. Royall DR, Palmer RF, Vidoni ED, Honea RA, Burns JM (2012) The default mode network and related right hemisphere structures may be the key substrates of dementia. J Alzheimers Dis 32, 467-478.
7. Royall DR, Palmer RF, Vidoni ED, Honea RA (2013) The default mode network may be the key substrate of depression related cognitive changes. J Alzheimers Dis 34, 547-560.
8. OBryant SE, Xiao G, Barber R, Reisch J, Hall J, Cullum CM, Doody R, Fairchild T, Adams P,Wilhelmsen K, Diaz-Arrastia R; Texas Alzheimers Research and Care Consortium (2011) A blood-based algorithm for the detection of Alzheimers disease. Dement Geriatr Cogn Disord 32, 55-62.
9. OBryant SE, Xiao G, Barber R, Huebinger R, Wilhelmsen K, Edwards M, Graff-Radford N, Doody R, Diaz-Arrastia R; Texas Alzheimers Research&Care Consortium; Alzheimers Disease Neuroimaging Initiative (2011) A blood-based screening tool for Alzheimers disease that spans serum and plasma: Findings from TARC and ADNI. PLoS One 6, e28092.
10. OBryant SE, Xiao G, Edwards M, Devous M, Gupta VB, Martins R, Zhang F, Barber R (2013) Biomarkers of Alzheimers disease among Mexican Americans. J Alzheimers Dis 34, 841-849.
11. Witte MM, Trzepacz P, Case M, Yu P, Hochstetler H, Quinlivan M, Sundell K, Henley D (2014) Association between clinical measures and florbetapir F18 PET neuroimaging in mild or moderate Alzheimers disease dementia. J Neuropsychiatry Clin Neurosci, doi: 10.1176/appi.neuropsych.12120402.
12. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM (1984) Clinical diagnosis of Alzheimers disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimers Disease. Neurology 34, 939-944.
13. Hughes CP, Berg L, Danziger WL, Coben LA, Martin RL (1982) A new clinical scale for the staging of dementia. Br J Psychiatry 140, 566-572.
14. Lawton MP, Brody EM (1969) Assessment of older people: Self-maintaining and instrumental activities of daily living. Gerontologist 9, 179-186.
15. Yesavage JA, Brink TL, Rose TL, Lum O, Huang V, Adey M, Leirer VO (1982) Development and validation of a geriatric depression screening scale: A preliminary report. J Am Geriatr Soc 29, 164-171.
16. Maixner SM, Burke WJ, Roccaforte WH, Wengel SP, Potter JF (1995)Acomparison of two depression scales in a geriatric assessment clinic. Am J Geriatr Psychiatry 3, 60-67.
17. Folstein MF, Folstein SE, McHugh PR (1975) Minimental state: A practical method for grading the cognitive state of patients for the clinician. J Psychiatry Res 12, 189-198.
18. Benton A, Hamsher K (1989) Multilingual Aphasia Examination. AJA Associates, Iowa City, Iowa.
19. Wechsler D (1997) Wechsler Memory Scale - Third Edition. The Psychological Corporation, San Antonio, TX.
20. Waring S, OBryant SE, Reisch JS, Diaz-Arrastia R, Knebl J, Doody R, for the Texas Alzheimers Research Consortium (2008) The Texas Alzheimers Research Consortium longitudinal research cohort: Study design and baseline characteristics. Texas Pub Health J 60, 9-13.
21. Koch W, Ehrenhaft A, Griesser K, Pfeufer A, Muller J, Schomig A, Kastrati A (2002) TaqMan systems for genotyping of disease-related polymorphisms present in the gene encoding apolipoprotein E. Clin Chem Lab Med 40, 1123-1131.
22. Arbuckle JL (2006) Analysis of Moment Structures-AMOS (Version 7.0) Computer Program], SPSS, Chicago.
23. Kaplan EF, Goodglass H, Weintraub S (1983) The Boston Naming Test, Experimental edition. Kaplan & Goodglass, Boston; 2nd ed., Lea & Febiger, Philadelphia.
24. Palmer R, Royall DR (2010) Missing data? Plan on it! J Am Geriatr Soc 58, S343-S348.
25. PASW Statistics 18, Release Version 18.0.0, SPSS, Inc., 2009, Chicago, IL.
26. Schafer JL, Graham JW (2002) Missing data: Our view of the state of the art. Psychol Methods 7, 147-177.
27. Graham JW (2009) Missing Data Analysis: Making it work in the real world. Ann Rev Psychol 6, 549-576.
28. Bollen KA, Long JS (1993) Testing Structural Equation Models. Sage Publications, Thousand Oaks, CA.
29. Wheaton B, Muthen B, AlwinDF, SummerGF(1977) Assessing reliability and stability in panel models. In Sociology Methodology, Heise DR, Ed. Jossey-Bass, San Francisco, CA.
30. Bentler PM (1990) Comparative fit indexes in structural models. Psychol Bull 107, 238-246.
31. Browne M, Cudeck R (1993) Alternative ways of assessing model fit. In Testing structural equation models, Bollen KA, Long JS, eds. Sage Publications, Thousand Oaks, CA, pp. 136-162.
32. Metz CE (1978) Basic principles of ROC analysis. Sem Nuc Med 8, 283-298.
33. Zweig MH, Campbell G (1993) Receiver-operating characteristic (ROC) plots: A fundamental evaluation tool in clinical medicine. Clin Chem 39, 561-577.
34. Raju NS, Laffitte LJ, Byrne BM (2008) Measurement equivalence: A comparison of methods based on confirmatory factor analysis and item response theory. J Appl Psychol 87, 517-529.
35. HankeML, Kielian T (2011) Toll-like receptors in health and disease in the brain: Mechanisms and therapeutic potential. Clin Sci (Lond) 121, 367-387.
36. Royall DR (2013) Fortress brain. Med Hypotheses 80, 118-121.
37. Minoretti P, Gazzaruso C, Vito DC, Emanuele E, Bianchi M, Coen ER, Eino M, Geroldi D (2006) Effect of the functional toll-like receptor Asp299Gly polymorphisms on susceptibility of late-onset Alzheimers disease. Neurosci Lett 391, 147-149.
38. Balistreri CR, Grimaldi MP, Chiappelli M, Licastro F, Castiglia L, Listi F, Vasto S, Lio D, Caruso C, Candore G (2008) Association between the polymorphisms of TLR4 and CD14 genes and Alzheimers disease. Curr Pharm Des 14, 2672-2677.
39. Wang LZ, Yu JT, Miao D, Wu ZC, Zong Y, Wen CQ, Tan L (2011) Genetic association of TLR4/11367 polymorphism with late-onset Alzheimers disease in a Han Chinese population. Brain Res 1381, 202-207.
40. Yu JT, Miao D, Cui WZ, Ou JR, Tian Y, Wu ZC, Zhang W, Tan L (2012) Common variants in toll-like receptor 4 confer susceptibility to Alzheimers disease in a Han Chinese population. Curr Alzheimer Res 9, 458-466.
41. Zhang W, Wang LZ, Yu JT, Chi ZF, Tan L (2012) Increased expressions of TLR2 and TLR4 on peripheral blood mononuclear cells from patients with Alzheimers disease. J Neurol Sci 315, 67-71.
42. Walter S, Letiembre M, Liu Y, Heine H, Penke B, Hao W, Manietta N, Walter J, Schulz-Schuffer W, Fassbender K (2007) Role of the toll-like receptor 4 in neuroinflammation in Alzheimers disease. Cell Physiol Biochem 20, 947-956.
43. Tahara K, Kim HD, Jin JJ, Maxwell JA, Li L, Fukuchi K (2006) Role of toll-like receptor signalling in Abeta uptake and clearance. Brain 129, 3006-3019.
44. Lucile C, Miller AH (2011) Immune system to brain signaling: Neuropsychopharmacological implications. Pharmacol Ther 130, 226-238.
45. Tang SC, Lathia JD, Selvaraj PK, Jo DG, Mughal MR, Cheng A, SilerDA, MarkesberyWR,ArumugamTV,Mattson MP (2008) Toll-like receptor-4 mediates neuronal apoptosis induced by amyloid beta-peptide and the membrane lipid peroxidation product 4-hydroxynonenal. Exp Neurol 213, 114-121.
46. He H, Genovese KJ, Swaggerty CL, MacKinnon KM, Kogut MH (2012) Co-stimulation with TLR3 and TLR21 ligands synergistically up-regulates Th1-cytokine IFN-c and regulatory cytokine IL-10 expression in chicken monocytes. Dev Comp Immunol 36, 756-760.
47. Arosio B, Mastronardi L, Vergani C, Annoni G (2010) Interleukin-10 promoter polymorphism in mild cognitive impairment and in its clinical evolution. Int J Alzheimers Dis 2010, pii: 854527.
48. Di Bona D, Rizzo C, Bonaventura G, Candore G, Caruso C (2012) Association between interleukin-10 polymorphisms and Alzheimers disease: A systematic review and metaanalysis. J Alzheimers Dis 29, 751-759.
49. Ribizzi G, Fiordoro S, Barocci S, Ferrari E, Megna M (2010) Cytokine polymorphisms and Alzheimer disease: Possible associations. Neurol Sci 31, 321-325.
50. Jacobson NG, Szabo SJ, Weber-Nordt RM, Zhong Z, Schreiber RD, Darnell JE, Murphy KM Jr (1995) Interleukin signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4. J Exp Med 181, 1755-1762.
51. Maruo S, Ahn HJ, Yu WG, Tomura M, Wysocka M, Yamamoto N, Kobayashi M, Hamaoka T, Trinchieri G, Fuijiwara H (1997) Establishment of an IL-12-responsive T cell clone: Its characterization and utilization in the quantitation of IL-12 activity. J Leukoc Biol 61, 346-352.
52. Berczi I, Bertok L, Chow DA (2000) Natural immunity and neuroimmune host defense. Ann N Y Acad Sci 917, 248-257.
53. Matera L, Mori M, Galetto A (2001) Effect of prolactin on the antigen presenting function of monocyte-derived dendritic cells. Lupus 10, 728-734.
54. Sprague DL, Sowa JM, Elzey BD, Ratliff TL (2007) The role of platelet CD154 in the modulation in adaptive immunity. Immunol Res 39, 185-193.
55. Cox D, Kerrigan SW, Watson SP (2011) Platelets and the innate immune system: Mechanisms of bacterial-induced platelet activation. J Thromb Haemost 9, 1097-1107.
56. Wallaschofski H, Donne M, Eigenthaler M, Hentschel B, Faber R, Stepan H, Koksch M, Lohmann T (2001) PRL as a novel potent cofactor for platelet aggregation. J Clin Endocrinol Metab 86, 5912-5919.
57. Kissel K, Berber S, Nockher A, Santoso S, Bein G, Hackstein H (2006) Human platelets target dendritic cell differentiation and production of proinflammatory cytokines. Transfusion 46, 818-827.
58. Cognasse F, Hamzeh H, Chavarin P, Acquart S, Genin C, Garraud O (2005) Evidence of Toll-like receptor molecules on human platelets. Immunol Cell Biol 83, 196-198.
59. Honjo K, van Reekum R, Verhoeff NP (2009) Alzheimers disease and infection: Do infectious agents contribute to progression of Alzheimers disease? Alzheimers Dement 5, 348-360.
60. Herbst-Kralovetz M, Pyles R (2006) Toll-like receptors, innate immunity and HSV pathogenesis. Herpes 13, 37-41.
61. Forghani B, Schmidt NJ (1983) Association of herpes simplex virus with platelets of experimentally infected mice. Arch Virol 76, 269-274.
62. Jamieson GA, Maitland NJ, Wilcock GK, Yates CM, Itzhaki RF (1992) Herpes simplex virus type 1 DNA is present in specific regions of brain from aged people with and without senile dementia of the Alzheimer type. J Pathol 167, 365-368.
63. Gordon L, McQuaid S, Cosby SL (1996) Detection of herpes simplex virus (types 1 and 2) and human herpes virus DNA in human brain tissue by polymerase chain reaction. Clin Diagnostic Virol 6, 33-40.
64. Lin WR, Graham J, MacGowan SM,Wilcock GK, Itzhaki RF (1998) Alzheimers disease, herpes virus in brain, apolipoprotein E4 and herpes labialis. Alzheimers Rep 1, 176-178.
65. Lin WR, Wozniak MA, Cooper RJ, Wilcock GK, Itzhaki RF (2002) Herpesviruses in brain and Alzheimers disease. J Pathology 197, 395-402.
66. Hemling N, Roytta M, Rinne J, Pollanen P, Broberg E, Tapio V, Vahlberg T, Hukkanen V (2003) Herpes viruses in brains in Alzheimers and Parkinsons diseases. Ann Neurol 54, 267-271.
67. Wang Q, Woltjer RL, Cimino PJ, Pan C, Montine KS, Zhang J, Montine TJ (2005) Proteomic analysis of neurofibrillary tangles in Alzheimer disease identifies GAPD as a detergentinsoluble paired helical filament tau binding protein. FASEB J 19, 869-871.
68. Liao L,Cheng D, Wang J, Duong DM, Losik TG, Gearing M, Rees HD, Lah JJ, Levey AI, Peng J (2004) Proteomic characterization of post mortem amyloid plaques isolated by laser capture micro dissection. J Biol Chem 279, 37061-37068.
69. Carter CJ (2011) Alzheimers disease plaques and tangles: Cemeteries of a pyrrhic victory of the immune defence network against herpes simplex infection at the expense of complement and inflammation-mediated neuronal destruction. Neurochem Int 58, 301-320.
70. Wozniak MA, Mee AP, Itzhaki RF (2009) Herpes simplex virus type 1 DNA is located within Alzheimers disease amyloid plaques. J Pathol 217, 131-138.
71. Kammerman EM, Neumann DM, Ball MJ, Lukiw W, Hill JM (2006) Senile plaques in Alzheimers diseased brains: Possible association of beta-amyloid with herpes simplex virus type 1 (HSV-1) L-particles. Med Hypotheses 66, 294-299.
72. Buckner RL, Sepulcre J, Talukdar T, Krienen FM, Liu H, Hedden T, Andrews-Hanna JR, Sperling RA, Johnson KA (2009) Cortical hubs revealed by intrinsic functional connectivity: Mapping, assessment of stability, and relation to Alzheimers disease. J Neurosci 29, 1860-1873.
73. Zou GM, Tam YK (2002) Cytokines in the generation and maturation of dendritic cells: Recent advances. Eur Cytokine Netw 13, 186-199.
74. Carpenter S, ONeill LA (2009) Recent insights into the structure of Toll-like receptors and post-translational modifications of their associated signalling proteins. Biochem J 422, 1-10.
75. Chang ZL (2010) Important aspects of Toll-like receptors, ligands and their signaling pathways. Inflamm Res 59, 791-808.
76. Mapstone M, Cheema AK, Fiandaca MS, Zhong X, Mhyre TR, Macarthur LH, Hall WJ, Fisher SG, Peterson DR, Haley JM, Nazar MD, Rich SA, Berlau DJ, Peltz CB, Tan MT, Kawas CH, Federoff HJ (2014) Plasma phospholipids identify antecedent memory impairment in older adults. Nat Med 20, 415-418.
77. Itzhaki RF, Wozniak MA, Appelt DM, Balin BJ (2004) Infiltration of the brain by pathogens causes Alzheimers disease. Neurobiol Aging 25, 619-627.
78. Carter C (2011) Alzheimers Disease: APP, gamma secretase, APOE, CLU, CR1, PICALM, ABCA7, BIN1, CD2AP, CD33, EPHA1, and MS4A2, and their relationships with herpes simplex, C. pneumoniae, other suspect pathogens, and the immune system. Int J Alzheimers Dis 2011, 501862.
79. Tang MX, Stern Y, Marder K, Bell K, Gurland B, Lantigua R, Andrews H, Feng L, Tycko B, Mayeux R (1998) The APOEepsilon4 allele and the risk of Alzheimer disease among African Americans, whites, and Hispanic persons. JAMA 279, 751-755.
80. Kwon OD, Khaleeq A, Chan W, Pavlik VN, Doody RS (2010) Apolipoprotein E polymorphism and age at onset of Alzheimers disease in a quadriethnic sample. Dement Geriatr Cogn Disord 30, 486-491.
81. Livney MG, Clark CM, Karlawish JH, Cartmell S, Negron M, Nunez J, Xie SX, Entenza-Cabrera F, Vega IE, Arnold SE (2011) Ethnoracial differences in the clinical characteristics of Alzheimers disease at initial presentation at an urban Alzheimers disease center. Am J Geriatr Psychiatry 19, 430-439.
82. Chin AL, Negash S, Hamilton R (2011) Diversity and disparity in dementia: The impact of ethnoracial differences in Alzheimer disease. Alzheimer Dis Assoc Disord 25, 187-195.
83. Acuna-Soto R, Stahle DW, Cleaveland MK, Therrell MD (2002) Megadrought and megadeath in 16th century Mexico. Emerg Infect Dis 8, 360-362.
84. Galvani AP, Novembre J (2005) The evolutionary history of the CCR5-Delta32 HIV-resistance mutation. Microbes Infect 7, 302-309.