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Volumn 9, Issue 10, 2014, Pages

Protective role of plant sterol and stanol esters in liver inflammation: Insights from mice and humans e110758

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER G1; CAMPESTANOL; CAMPESTEROL; DESMOSTEROL; LATHOSTEROL; LIVER X RECEPTOR ALPHA; PHYTOSTEROL; SITOSTANOL; SITOSTEROL; STANOL ESTER; TUMOR NECROSIS FACTOR ALPHA; CHOLESTEROL; FAT INTAKE;

EID: 84908691402     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0110758     Document Type: Article
Times cited : (50)

References (22)
  • 2
    • 0036403449 scopus 로고    scopus 로고
    • Phytosterols in human nutrition
    • Ostlund RE Jr (2002) Phytosterols in human nutrition. Annual review of nutrition 22: 533-549.
    • (2002) Annual review of nutrition , vol.22 , pp. 533-549
    • Ostlund, R.E.1
  • 3
    • 79958219975 scopus 로고    scopus 로고
    • Plant sterols and stanols in the treatment of dyslipidemia: New insights into targets and mechanisms related to cardiovascular risk
    • Baumgartner S, Mensink RP, Plat J (2011) Plant sterols and stanols in the treatment of dyslipidemia: new insights into targets and mechanisms related to cardiovascular risk. Current pharmaceutical design 17: 922-932.
    • (2011) Current pharmaceutical design , vol.17 , pp. 922-932
    • Baumgartner, S.1    Mensink, R.P.2    Plat, J.3
  • 4
    • 49649110937 scopus 로고    scopus 로고
    • Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis
    • Wouters K, van Gorp PJ, Bieghs V, Gijbels MJ, Duimel H, et al. (2008) Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis. Hepatology 48: 474-486.
    • (2008) Hepatology , vol.48 , pp. 474-486
    • Wouters, K.1    Van Gorp, P.J.2    Bieghs, V.3    Gijbels, M.J.4    Duimel, H.5
  • 6
    • 84867031028 scopus 로고    scopus 로고
    • Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses
    • Spann NJ, Garmire LX, McDonald JG, Myers DS, Milne SB, et al. (2012) Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses. Cell 151: 138-52.
    • (2012) Cell , vol.151 , pp. 138-152
    • Spann, N.J.1    Garmire, L.X.2    McDonald, J.G.3    Myers, D.S.4    Milne, S.B.5
  • 7
    • 84859081972 scopus 로고    scopus 로고
    • Internalization of modified lipids by cd36 and SR-A leads to hepatic inflammation and lysosomal cholesterol storage in kupffer cells
    • Bieghs V, Verheyen F, van Gorp PJ, Hendrikx T, Wouters K, et al. (2012) Internalization of modified lipids by CD36 and SR-A leads to hepatic inflammation and lysosomal cholesterol storage in Kupffer cells. PloS one 7: e34378.
    • (2012) PloS one , vol.7 , pp. e34378
    • Bieghs, V.1    Verheyen, F.2    Van Gorp, P.J.3    Hendrikx, T.4    Wouters, K.5
  • 8
    • 84867584238 scopus 로고    scopus 로고
    • Beneficial effects of sitostanol on the attenuated immune function in asthma patients: Results of an in vitro approach
    • Brull F, Mensink RP, Steinbusch MF, Husche C, Lutjohann D, et al. (2012) Beneficial effects of sitostanol on the attenuated immune function in asthma patients: results of an in vitro approach. PloS one 7: e46895.
    • (2012) PloS one , vol.7 , pp. e46895
    • Brull, F.1    Mensink, R.P.2    Steinbusch, M.F.3    Husche, C.4    Lutjohann, D.5
  • 9
    • 77449155592 scopus 로고    scopus 로고
    • Tlr2 activation is essential to induce a th1 shift in human peripheral blood mononuclear cells by plant stanols and plant sterols
    • Brull F, Mensink RP, van den Hurk K, Duijvestijn A, Plat J (2010) TLR2 activation is essential to induce a Th1 shift in human peripheral blood mononuclear cells by plant stanols and plant sterols. The Journal of Biological Chemistry 285: 2951-2958.
    • (2010) The Journal of Biological Chemistry , vol.285 , pp. 2951-2958
    • Brull, F.1    Mensink, R.P.2    Van Den Hurk, K.3    Duijvestijn, A.4    Plat, J.5
  • 10
    • 77049094855 scopus 로고    scopus 로고
    • Intrahepatic cholesterol influences progression, inhibition and reversal of non-alcoholic steatohepatitis in hyperlipidemic mice
    • Wouters K, van Bilsen M, van Gorp PJ, Bieghs V, Lutjohann D, et al. (2010) Intrahepatic cholesterol influences progression, inhibition and reversal of non-alcoholic steatohepatitis in hyperlipidemic mice. FEBS letters 584: 1001-1005.
    • (2010) FEBS letters , vol.584 , pp. 1001-1005
    • Wouters, K.1    Van Bilsen, M.2    Van Gorp, P.J.3    Bieghs, V.4    Lutjohann, D.5
  • 11
    • 27444436469 scopus 로고    scopus 로고
    • Plant sterols and stanols: Effects on mixed micellar composition and LXR (target gene) activation
    • Plat J, Nichols JA, Mensink RP (2005) Plant sterols and stanols: effects on mixed micellar composition and LXR (target gene) activation. J Lipid Res 46: 2468-76.
    • (2005) J Lipid Res , vol.46 , pp. 2468-2476
    • Plat, J.1    Nichols, J.A.2    Mensink, R.P.3
  • 12
    • 9644281617 scopus 로고    scopus 로고
    • Disruption of cholesterol homeostasis by plant sterols
    • Yang C, Yu L, Li W, Xu F, Cohen JC, et al. (2004) Disruption of cholesterol homeostasis by plant sterols. J Clin Invest 114: 813-22.
    • (2004) J Clin Invest , vol.114 , pp. 813-822
    • Yang, C.1    Yu, L.2    Li, W.3    Xu, F.4    Cohen, J.C.5
  • 13
    • 84879604697 scopus 로고    scopus 로고
    • Intestinal microbiota in patients with non-alcoholic fatty liver disease
    • Mouzaki M, Comelli E, Arendt B, Bonengel J, Fung S, et al. (2013) Intestinal microbiota in patients with non-alcoholic fatty liver disease. Hepatology 58: 120-127.
    • (2013) Hepatology , vol.58 , pp. 120-127
    • Mouzaki, M.1    Comelli, E.2    Arendt, B.3    Bonengel, J.4    Fung, S.5
  • 14
    • 84871886012 scopus 로고    scopus 로고
    • Diet-induced alterations of host cholesterol metabolism are likely to affect the gut microbiota composition in hamsters
    • Martinez I, Perdicaro DJ, Brown AW, Hammons S, Carden TJ, et al. (2013) Diet-induced alterations of host cholesterol metabolism are likely to affect the gut microbiota composition in hamsters. Applied and environmental microbiology 79: 516-524.
    • (2013) Applied and environmental microbiology , vol.79 , pp. 516-524
    • Martinez, I.1    Perdicaro, D.J.2    Brown, A.W.3    Hammons, S.4    Carden, T.J.5
  • 15
    • 77954366025 scopus 로고    scopus 로고
    • Efficacy of ezetimibe for the treatment of non-alcoholic steatohepatitis: An open-label, pilot study
    • Yoneda M, Fujita K, Nozaki Y, Endo H, Takahashi H, et al. (2010) Efficacy of ezetimibe for the treatment of non-alcoholic steatohepatitis: An open-label, pilot study. Hepatol Res 40: 566-73.
    • (2010) Hepatol Res , vol.40 , pp. 566-573
    • Yoneda, M.1    Fujita, K.2    Nozaki, Y.3    Endo, H.4    Takahashi, H.5
  • 16
    • 77952717393 scopus 로고    scopus 로고
    • Role of scavenger receptor A and cd36 in diet-induced nonalcoholic steatohepatitis in hyperlipidemie mice
    • Bieghs V, Wouters K, van Gorp PJ, Gijbels MJ, de Winther MP, et al. (2010) Role of scavenger receptor A and CD36 in diet-induced nonalcoholic steatohepatitis in hyperlipidemie mice. Gastroenterology 138: 2477-2486.
    • (2010) Gastroenterology , vol.138 , pp. 2477-2486
    • Bieghs, V.1    Wouters, K.2    Van Gorp, P.J.3    Gijbels, M.J.4    De Winther, M.P.5
  • 17
    • 84871330823 scopus 로고    scopus 로고
    • The cholesterol derivative 27-hydroxycholesterol reduces steatohepatitis in mice
    • Bieghs V, Hendrikx T, van Gorp PJ, Verheyen F, Guichot YD, et al. (2013) The cholesterol derivative 27-hydroxycholesterol reduces steatohepatitis in mice. Gastroenterology 144: 167-178.
    • (2013) Gastroenterology , vol.144 , pp. 167-178
    • Bieghs, V.1    Hendrikx, T.2    Van Gorp, P.J.3    Verheyen, F.4    Guichot, Y.D.5
  • 18
    • 33745109326 scopus 로고    scopus 로고
    • High-dose statin treatment does not alter plasma marker for brain cholesterol metabolism in patients with moderately elevated plasma cholesterol levels
    • Thelen KM, Laaksonen R, Päivä H, Lehtimäki T, Lütjohann D (2006) High-dose statin treatment does not alter plasma marker for brain cholesterol metabolism in patients with moderately elevated plasma cholesterol levels. J Clin Pharmacol 46: 812-6.
    • (2006) J Clin Pharmacol , vol.46 , pp. 812-816
    • Thelen, K.M.1    Laaksonen, R.2    Päivä, H.3    Lehtimäki, T.4    Lütjohann, D.5
  • 20
    • 73149110853 scopus 로고    scopus 로고
    • Activation of the complement system in human nonalcoholic fatty liver disease
    • Rensen SS, Slaats Y, Driessen A, Peutz-Kootstra CJ, Nijhuis J, et al. (2009) Activation of the complement system in human nonalcoholic fatty liver disease. Hepatology 50: 1809-17.
    • (2009) Hepatology , vol.50 , pp. 1809-1817
    • Rensen, S.S.1    Slaats, Y.2    Driessen, A.3    Peutz-Kootstra, C.J.4    Nijhuis, J.5
  • 22
    • 20044374023 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis clinical research network. Design and validation of a histological scoring system for nonalcoholic fatty liver disease
    • Kleiner DE, Brunt EM, Van Natta M, Behling C, Contos MJ, et al. (2005) Nonalcoholic Steatohepatitis Clinical Research Network. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology 41: 1313-21.
    • (2005) Hepatology , vol.41 , pp. 1313-1321
    • Kleiner, D.E.1    Brunt, E.M.2    Van Natta, M.3    Behling, C.4    Contos, M.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.