Thyroglobulin autoantibodies switch to immunoglobulin (Ig)G1 and IgG3 subclasses and preserve their restricted epitope pattern after 131I treatment for Graves' hyperthyroidism: The activity of autoimmune disease influences subclass distribution but not epitope pattern of autoantibodies

Clinical and Experimental Immunology

Volumn 178, Issue 3, 2014, Pages 438-446

  Latrofa, F ^a   Ricci, D ^a   Montanelli, L ^a   Piaggi, P ^b   Mazzi, B ^a   Bianchi, F ^a   Brozzi, F ^a   Santini, P ^a   Fiore, E ^a   Marino M ^a   Tonacchera, M ^a   Vitti, P ^a  

^a UNIVERSITY HOSPITAL OF PISA   (Italy)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

B cell epitopes; Graves' disease; IgG subclasses; Intramolecular epitope spreading; Thyroglobulin autoantibodies

Indexed keywords

AUTOANTIBODY; EPITOPE; IMMUNOGLOBULIN G; RADIOACTIVE IODINE; THYROGLOBULIN;

ADULT; BLOOD; CLASSIFICATION; FEMALE; GRAVES DISEASE; HUMAN; IMMUNOLOGY; MALE;

ADULT; AUTOANTIBODIES; EPITOPES; FEMALE; GRAVES DISEASE; HUMANS; IMMUNOGLOBULIN G; IODINE RADIOISOTOPES; MALE; THYROGLOBULIN;

EID: 84908681984     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/cei.12438     Document Type: Article

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