IL-27 induces the production of IgG1 by human B cells

European Cytokine Network

Volumn 17, Issue 4, 2006, Pages 281-289

  Boumendjel, Amel ^a,b   Tawk, Lina ^a   Malefijt, René de Waal ^c   Boulay, Vera ^a   Yssel, Hans ^a   Pène, Jérôme ^a  

^a INSERM   (France)

^b BADJI MOKHTAR UNIVERSITY   (Algeria)

^c MERCK RESEARCH LABORATORIES   (United States)

Author keywords

B cell; Cytokines; Immunoglobulin; Interleukin 27; Isotype switching

Indexed keywords

CD19 ANTIGEN; CD27 ANTIGEN; CD40 ANTIGEN; IMMUNOGLOBULIN CLASS; IMMUNOGLOBULIN G; INTERLEUKIN 10; INTERLEUKIN 21; INTERLEUKIN 4; INTERLEUKIN DERIVATIVE; MONOCLONAL ANTIBODY;

ARTICLE; B LYMPHOCYTE; BLOOD; CELL CULTURE; CELL DIFFERENTIATION; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; FETUS BLOOD; FLOW CYTOMETRY; HUMAN; IMMUNOLOGY; SPLEEN;

ANTIBODIES, MONOCLONAL; ANTIGENS, CD19; ANTIGENS, CD27; ANTIGENS, CD40; B-LYMPHOCYTES; CELL DIFFERENTIATION; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; FETAL BLOOD; FLOW CYTOMETRY; HUMANS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN ISOTYPES; INTERLEUKIN-10; INTERLEUKIN-4; INTERLEUKINS; SPLEEN;

EID: 34249996831     PISSN: 11485493     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. + T Cells. Immunity 2002; 16: 779.
2. Larousserie F, Pflanz S, Coulomb-L'Hermine A, et al. Expression of IL-27 in human Th1-associated granulomatous diseases. J Pathol 2004; 202: 164.
3. Larousserie F, Bardel E, Pflanz S, et al. Analysis of interleukin-27 (EBI3/p28) expression in Epstein-Barr virus and human T-cell leukemia virus type 1-associated lymphomas: heterogeneous expression of EBI3 subunit by tumoral cells. Am J Pathol 2005; 166: 1217.
4. Devergne O, Hummel M, Koeppen H, et al. A novel interleukin-12 p40-related protein induced by latent Epstein-Barr virus infection in B lymphocytes. J Virol 1996; 70: 1143.
5. Brombacher F, Kastelein RA, Alber G. Novel IL-12 family members shed light on the orchestration of Th1 responses. Trends Immunol 2003; 24: 207.
6. Pflanz S, Hibbert L, Mattson J, et al. WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27. J Immunol 2004; 172: 2225.
7. Kishimoto T. Interleukin-6: from basic science to medicine-40 years in immunology. Annu Rev Immunol 2005; 23: 1.
8. Batten M, Li J, Yi S, Kljavin NM, et al. Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells. Nat Immunol 2006; 9: 929.
9. Stumhofer J, Laurence A, Wilson E, et al. Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system. Nat Immunol 2006; 9: 937.
10. Chen Q, Ghilardi N, Wang H, et al. Development of Th1-type immune responses requires the type I cytokine receptor TCCR. Nature 2000; 407: 916.
11. Yoshimoto T, Okada K, Morishima N, et al. Induction of IgG2a Class Switching in B Cells by IL-27. J Immunol 2004; 173: 2479.
12. Miyazaki Y, Inoue H, Matsumura M, et al. Exacerbation of experimental allergic asthma by augmented Th2 responses in WSX-1-deficient mice. J Immunol 2005; 175: 2401.
13. Larousserie F, Charlot P, Bardel E, et al. Differential effects of IL-27 on human B cell subsets. J Immunol 2006; 176: 5890.
14. Pène J, Gauchat J-F, Lécart S, et al. Cutting Edge: IL-21 is a switch factor for the Ppoduction of IgG1 and IgG3 by human B cells. J Immunol 2004; 172: 5154.
15. Scheffold A, Assenmacher M, Radbruch A. Phenotyping and separation of leukocyte populations based on affinity labelling. In: Kaufman S, Kabelitz D, eds. Immunology of Infection. 2nd ed. London: Academic Press, 2002: 25.
16. Berger M, Albrecht B, Berces A, et al. S(+)-4-(1-Phenylethylamino) quinazolines as inhibitors of human immunoglobulin E synthesis: potency is dictated by stereochemistry and atomic point charges at N-1. J Med Chem 2001; 44: 3031.
17. Valle A, Zuber C, Defrance T, et al. Activation of human B lymphocytes through CD40 and interleukin 4. Eur J Immunol 1989; 8: 1463.
18. Yssel H, De Vries JE, Koken M, et al. Serum-free medium for generation and propagation of functional human cytotoxic and helper T cell clones. J Immunol Methods 1984; 72: 219.
19. Lelièvre E, Plun-Favreau H, Chevalier S, et al. Signaling pathways recruited by the cardiotrophin-like cytokine/cytokine-like factor-1 composite cytokine: specific requirement of the membrane-bound form of ciliary neurotrophic factor receptor alpha component. J Biol Chem 2001; 276: 22476.
20. Banchereau J, Bazan F, Blanchard D, et al. The CD40 antigen and itslLigand. Annu Rev Immunol 1994; 12: 881.
21. Honjo T, Kinoshita K, Muramatsu M. Molecular mechanism of class switch recombination: linkage with somatic hypermutation. Annu Rev Immunol 2002; 20: 165.
22. Gagro A, Servis D, Cepika AM, et al. Type I cytokine profiles of human naive and memory B lymphocytes: a potential for memory cells to impact polarization. Immunology 2006; 118: 66.
23. Arce E, Jackson DG, Gill MA, et al. Increased frequency of pre-germinal center B cells and plasma cell precursors in the blood of children with systemic lupus erythematosus. J Immunol 2001; 167: 2361.
24. + B cells in human lymphatic organs: re-evaluating the splenic marginal zone. Immunology 2005; 116: 429.
25. Ettinger R, Sims GP, Fairhurst AM, et al. IL-21 Induces differentiation of human naive and memory B cells into antibody-secreting plasma cells. J Immunol 2005; 175: 7867.
26. Tangye SG, Ferguson A, Avery DT, et al. Isotype switching by human B cells is division-associated and regulated by cytokines. J Immunol 2002; 169: 4298.
27. Tangye SG, Avery DT, Deenick EK, et al. Intrinsic differences in the proliferation of naive and memory human B cells as a mechanism for enhanced secondary immune responses. J Immunol 2003; 170: 686.
28. Fecteau JF, Neron S. CD40 Stimulation of human peripheral B lymphocytes: distinct response from naive and memory cells. J Immunol 2003; 171: 4621.
29. Snapper CM, Peschel C, Paul WE. IFN-gamma stimulates IgG2a secretion by murine B cells stimulated with bacterial lipopolysaccharide. J Immunol 1988; 140: 2121.
30. Shimizu S, Sugiyama N, Masutani K, et al. Membranous glomerulonephritis development with Th2-type immune deviations in MRL/ lpr mice deficient for IL-27 receptor (WSX-1). J Immunol 2005; 175: 7185.
31. +) B cells to secrete IgG1 and IgG3. J Exp Med 1994; 179: 757.
32. Fujieda S, Saxon A, Zhang K. Direct evidence that gamma 1 and gamma 3 switching in human B cells is interleukin-10 dependent. Mol Immunol 1996; 33: 1335.
33. Hayashida H, Miyata T, Yamawaki-Kataoka Y, et al. Concerted evolution of the mouse immunoglobulin gamma chain genes. EMBO J 1984; 3: 2047.