Intralipid, a clinically safe compound, protects the heart against ischemia-reperfusion injury more efficiently than cyclosporine-A

Anesthesiology

Volumn 117, Issue 4, 2012, Pages 836-846

  Li, Jingyuan ^a   Iorga, Andrea ^a   Sharma, Salil ^a   Youn, Ji Youn ^a   Partow Navid, Rod ^a   Umar, Soban ^a   Cai, Hua ^a   Rahman, Siamak ^a   Eghbali, Mansoureh ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CYCLOSPORIN A; GLYCOGEN SYNTHASE KINASE 3BETA; INTRALIPID; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; PROTEIN KINASE B; SUPEROXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; EX VIVO STUDY; HEART HEMODYNAMICS; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART PROTECTION; IN VIVO STUDY; ISOLATED HEART; MALE; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY;

ANIMALS; ANTERIOR WALL MYOCARDIAL INFARCTION; BLOTTING, WESTERN; CALCIUM; CARDIOTONIC AGENTS; CORONARY VESSELS; CYCLOSPORINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRON SPIN RESONANCE SPECTROSCOPY; EMULSIONS; FAT EMULSIONS, INTRAVENOUS; GLYCOGEN SYNTHASE KINASE 3; HEART FUNCTION TESTS; IMMUNOSUPPRESSIVE AGENTS; MALE; MICE; MICE, INBRED C57BL; MITOCHONDRIA, HEART; MYOCARDIAL REPERFUSION INJURY; NECROSIS; ONCOGENE PROTEIN V-AKT; PERMEABILITY; PHOSPHOLIPIDS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SOYBEAN OIL;

EID: 84866742734     PISSN: 00033022     EISSN: 15281175     Source Type: Journal    
DOI: 10.1097/ALN.0b013e3182655e73     Document Type: Article

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