Post-cardiac arrest myocardial dysfunction is improved with cyclosporine treatment at onset of resuscitation but not in the reperfusion phase

Resuscitation

Volumn 82, Issue SUPPL. 2, 2011, Pages

  Huang, Chien Hua ^a,b   Tsai, Min Shan ^a   Hsu, Chiung Yuan ^a   Su, Yu Jen ^a   Wang, Tzung Dau ^b   Chang, Wei Tien ^a   Chen, Wen Jone ^a,b  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Cardioprotection; Cardiopulmonary resuscitation; Cyclosporine; Mitochondria; Myocardial dysfunction; Post cardiac arrest syndrome; Rat; Therapeutic window

Indexed keywords

CYCLOSPORIN; CYCLOSPORIN A; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; PLACEBO;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIASTOLE; HEART ARREST; HEART LEFT VENTRICLE CONTRACTION; HEART LEFT VENTRICLE FUNCTION; HEART OUTPUT; MALE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION SWELLING; MYOCARDIAL DISEASE; NONHUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RAT; REPERFUSION INJURY; RESUSCITATION; RETURN OF SPONTANEOUS CIRCULATION; SURVIVAL TIME; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; CARDIOPULMONARY RESUSCITATION; CYCLOSPORINE; DISEASE MODELS, ANIMAL; HEART ARREST; IMMUNOSUPPRESSIVE AGENTS; MALE; MYOCARDIAL CONTRACTION; RATS; RATS, WISTAR; REPERFUSION INJURY; VENTRICULAR DYSFUNCTION; VENTRICULAR FUNCTION;

EID: 84855171197     PISSN: 03009572     EISSN: 18731570     Source Type: Journal    
DOI: 10.1016/S0300-9572(11)70150-2     Document Type: Article

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