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Volumn 25, Issue 21, 2014, Pages 3308-3318

RNA-binding protein HuR promotes growth of small intestinal mucosa by activating the Wnt signaling pathway

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; HUR PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; MESSENGER RNA; SMAD7 PROTEIN; SMALL INTERFERING RNA; UVOMORULIN; WNT PROTEIN; 3' UNTRANSLATED REGION; ELAV PROTEIN; LRP6 PROTEIN, MOUSE;

EID: 84908621202     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E14-03-0853     Document Type: Article
Times cited : (65)

References (51)
  • 2
    • 55549114048 scopus 로고    scopus 로고
    • JunD represses transcription and translation of the tight junction protein zona occludens-1 modulating intestinal epithelial barrier function
    • Chen J, Xiao L, Rao JN, Zou T, Liu L, Bellavance E, Gorospe M, Wang JY (2008). JunD represses transcription and translation of the tight junction protein zona occludens-1 modulating intestinal epithelial barrier function. Mol Biol Cell 19, 3701-3712.
    • (2008) Mol Biol Cell , vol.19 , pp. 3701-3712
    • Chen, J.1    Xiao, L.2    Rao, J.N.3    Zou, T.4    Liu, L.5    Bellavance, E.6    Gorospe, M.7    Wang, J.Y.8
  • 3
    • 80051693551 scopus 로고    scopus 로고
    • The RNA-binding protein ELAVL1/HuR is essential for mouse spermatogenesis, acting both at meiotic and postmeiotic stages
    • Chi MN, Auriol J, Jegou B, Kontoyiannis DL, Turner JM, de Rooij DG, Morello D (2011). The RNA-binding protein ELAVL1/HuR is essential for mouse spermatogenesis, acting both at meiotic and postmeiotic stages. Mol Biol Cell 22, 2875-2885.
    • (2011) Mol Biol Cell , vol.22 , pp. 2875-2885
    • Chi, M.N.1    Auriol, J.2    Jegou, B.3    Kontoyiannis, D.L.4    Turner, J.M.5    De Rooij, D.G.6    Morello, D.7
  • 4
    • 33746808398 scopus 로고    scopus 로고
    • Wnt/b-catenin signaling in development and disease
    • Clevers H (2006). Wnt/b-catenin signaling in development and disease. Cell 127, 469-480.
    • (2006) Cell , vol.127 , pp. 469-480
    • Clevers, H.1
  • 7
    • 2942612333 scopus 로고    scopus 로고
    • A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machinery
    • Gherzi R, Lee KY, Briata P, Wegmuller D, Moroni C, Karin M, Chen CY (2004). A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machinery. Mol Cell 14, 571-583.
    • (2004) Mol Cell , vol.14 , pp. 571-583
    • Gherzi, R.1    Lee, K.Y.2    Briata, P.3    Wegmuller, D.4    Moroni, C.5    Karin, M.6    Chen, C.Y.7
  • 9
    • 84907546688 scopus 로고    scopus 로고
    • Intestinal epithelial HuR modulates distinct pathways of proliferation and apoptosis and attenuates small intestinal and colonic tumor development
    • Giammanco A, Blanc V, Montenegro G, Klos C, Xie Y, Kennedy S, Luo J, Chang SH, Hla T, Nalbantoglu I, et al. (2014). Intestinal epithelial HuR modulates distinct pathways of proliferation and apoptosis and attenuates small intestinal and colonic tumor development. Cancer Res 74, 5322-5335.
    • (2014) Cancer Res , vol.74 , pp. 5322-5335
    • Giammanco, A.1    Blanc, V.2    Montenegro, G.3    Klos, C.4    Xie, Y.5    Kennedy, S.6    Luo, J.7    Chang, S.H.8    Hla, T.9    Nalbantoglu, I.10
  • 10
    • 84878768244 scopus 로고    scopus 로고
    • Apoptosis, necrosis and necroptosis: Cell death regulation in the intestinal epithelium
    • Gunther C, Neumann H, Neurath MF, Becker C (2013). Apoptosis, necrosis and necroptosis: cell death regulation in the intestinal epithelium. Gut 62, 1062-1071.
    • (2013) Gut , vol.62 , pp. 1062-1071
    • Gunther, C.1    Neumann, H.2    Neurath, M.F.3    Becker, C.4
  • 11
    • 2342430345 scopus 로고    scopus 로고
    • LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: Arrows point the way
    • He X, Semenov M, Tamai K, Zeng X (2004). LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: arrows point the way. Development 131, 1663-1677.
    • (2004) Development , vol.131 , pp. 1663-1677
    • He, X.1    Semenov, M.2    Tamai, K.3    Zeng, X.4
  • 12
    • 60149090021 scopus 로고    scopus 로고
    • The many pathways of RNA degradation
    • Houseley J, Tollervey D (2009). The many pathways of RNA degradation. Cell 136, 763-776.
    • (2009) Cell , vol.136 , pp. 763-776
    • Houseley, J.1    Tollervey, D.2
  • 13
    • 0023943251 scopus 로고
    • Regulation of gastrointestinal mucosal growth
    • Johnson LR (1988). Regulation of gastrointestinal mucosal growth. Physiol Rev 68, 456-502.
    • (1988) Physiol Rev , vol.68 , pp. 456-502
    • Johnson, L.R.1
  • 16
    • 34250735674 scopus 로고    scopus 로고
    • RNA regulons: Coordination of post-transcriptional events
    • Keene JD (2007). RNA regulons: coordination of post-transcriptional events. Nat Rev Genet 8, 533-543.
    • (2007) Nat Rev Genet , vol.8 , pp. 533-543
    • Keene, J.D.1
  • 18
    • 4143122397 scopus 로고    scopus 로고
    • Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs
    • Lal A, Mazan-Mamczarz K, Kawai T, Yang X, Martindale JL, Gorospe M (2004). Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs. EMBO J 23, 3092-3102.
    • (2004) EMBO J , vol.23 , pp. 3092-3102
    • Lal, A.1    Mazan-Mamczarz, K.2    Kawai, T.3    Yang, X.4    Martindale, J.L.5    Gorospe, M.6
  • 21
    • 84871363415 scopus 로고    scopus 로고
    • HuR cytoplasmic expression is associated with increased cyclin A expression and poor outcome with upper urinary tract urothelial carcinoma
    • Liang PI, Li WM, Wang YH, Wu TF, Wu WR, Liao AC, Shen KH, Wei YC, Hsing CH, Shiue YL, et al. (2012). HuR cytoplasmic expression is associated with increased cyclin A expression and poor outcome with upper urinary tract urothelial carcinoma. BMC Cancer 12, 611.
    • (2012) BMC Cancer , vol.12 , pp. 611
    • Liang, P.I.1    Li, W.M.2    Wang, Y.H.3    Wu, T.F.4    Wu, W.R.5    Liao, A.C.6    Shen, K.H.7    Wei, Y.C.8    Hsing, C.H.9    Shiue, Y.L.10
  • 22
    • 34249875986 scopus 로고    scopus 로고
    • Competitive binding of AUF1 and TIAR to MYC mRNA controls its translation
    • Liao B, Hu Y, Brewer G (2007). Competitive binding of AUF1 and TIAR to MYC mRNA controls its translation. Nat Struct Mol Biol 14, 511-518.
    • (2007) Nat Struct Mol Biol , vol.14 , pp. 511-518
    • Liao, B.1    Hu, Y.2    Brewer, G.3
  • 23
    • 10644274455 scopus 로고    scopus 로고
    • Polyamine-modulated expression of c-myc plays a critical role in stimulation of normal intestinal epithelial cell proliferation
    • Liu L, Li L, Rao JN, Zou T, Zhang HM, Boneva D, Bernard MS, Wang JY (2005). Polyamine-modulated expression of c-myc plays a critical role in stimulation of normal intestinal epithelial cell proliferation. Am J Physiol Cell Physiol 288, C89-C99.
    • (2005) Am J Physiol Cell Physiol , vol.288 , pp. C89-C99
    • Liu, L.1    Li, L.2    Rao, J.N.3    Zou, T.4    Zhang, H.M.5    Boneva, D.6    Bernard, M.S.7    Wang, J.Y.8
  • 24
    • 83455250348 scopus 로고    scopus 로고
    • Activation of Wnt3a signaling stimulates intestinal epithelial repair by promoting c-Myc-regulated gene expression
    • Liu L, Rao JN, Zou T, Xiao L, Smith A, Zhuang R, Turner DJ, Wang JY (2012). Activation of Wnt3a signaling stimulates intestinal epithelial repair by promoting c-Myc-regulated gene expression. Am J Physiol Cell Physiol 302, C277-C285.
    • (2012) Am J Physiol Cell Physiol , vol.302 , pp. C277-C285
    • Liu, L.1    Rao, J.N.2    Zou, T.3    Xiao, L.4    Smith, A.5    Zhuang, R.6    Turner, D.J.7    Wang, J.Y.8
  • 27
    • 84858379476 scopus 로고    scopus 로고
    • MicroRNAs in stress signaling and human disease
    • Mendell JT, Olson EN (2012). MicroRNAs in stress signaling and human disease. Cell 148, 1172-1187.
    • (2012) Cell , vol.148 , pp. 1172-1187
    • Mendell, J.T.1    Olson, E.N.2
  • 28
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann T (1983). Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65, 55-63.
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 32
    • 84878760040 scopus 로고    scopus 로고
    • Growing self-organizing mini-guts from a single intestinal stem cell: Mechanism and applications
    • Sato T, Clevers H (2013). Growing self-organizing mini-guts from a single intestinal stem cell: mechanism and applications. Science 340, 1190-1194.
    • (2013) Science , vol.340 , pp. 1190-1194
    • Sato, T.1    Clevers, H.2
  • 33
    • 84863927610 scopus 로고    scopus 로고
    • Functional interplay between RNA-binding protein HuR and microRNAs
    • Srikantan S, Tominaga K, Gorospe M (2012). Functional interplay between RNA-binding protein HuR and microRNAs. Curr Protein Peptide Sci 13, 372-379.
    • (2012) Curr Protein Peptide Sci , vol.13 , pp. 372-379
    • Srikantan, S.1    Tominaga, K.2    Gorospe, M.3
  • 35
    • 34547680515 scopus 로고    scopus 로고
    • Polyamines and mRNA stability in regulation of intestinal mucosal growth
    • Wang JY (2007). Polyamines and mRNA stability in regulation of intestinal mucosal growth. Amino Acids 33, 241-252.
    • (2007) Amino Acids , vol.33 , pp. 241-252
    • Wang, J.Y.1
  • 36
    • 0028121520 scopus 로고
    • Expression of protooncogenes c-fos and c-myc in healing of gastric mucosal stress ulcers
    • Wang JY, Johnson LR (1994). Expression of protooncogenes c-fos and c-myc in healing of gastric mucosal stress ulcers. Am J Physiol Gastrointest Liver Physiol 266, G878-G886.
    • (1994) Am J Physiol Gastrointest Liver Physiol , vol.266 , pp. G878-G886
    • Wang, J.Y.1    Johnson, L.R.2
  • 37
    • 77951473777 scopus 로고    scopus 로고
    • Post-transcriptional regulation of MEK-1 by polyamines through the RNA-binding protein HuR modulating intestinal epithelial apoptosis
    • Wang PY, Rao JN, Zou T, Liu L, Xiao L, Yu TX, Turner DJ, Gorospe M, Wang JY (2010). Post-transcriptional regulation of MEK-1 by polyamines through the RNA-binding protein HuR modulating intestinal epithelial apoptosis. Biochem J 426, 293-306.
    • (2010) Biochem J , vol.426 , pp. 293-306
    • Wang, P.Y.1    Rao, J.N.2    Zou, T.3    Liu, L.4    Xiao, L.5    Yu, T.X.6    Turner, D.J.7    Gorospe, M.8    Wang, J.Y.9
  • 38
    • 0042850578 scopus 로고    scopus 로고
    • Total parenteral nutrition-induced apoptosis in mouse intestinal epithelium: Modulation by keratinocyte growth factor
    • Wildhaber BE, Yang H, Teitelbaum DH (2003). Total parenteral nutrition-induced apoptosis in mouse intestinal epithelium: modulation by keratinocyte growth factor. J Surg Res 112, 144-151.
    • (2003) J Surg Res , vol.112 , pp. 144-151
    • Wildhaber, B.E.1    Yang, H.2    Teitelbaum, D.H.3
  • 40
    • 80052220142 scopus 로고    scopus 로고
    • Regulation of cyclin-dependent kinase 4 translation through CUG-binding protein 1 and microRNA-222 by polyamines
    • Xiao L, Cui YH, Rao JN, Zou T, Liu L, Smith A, Turner DJ, Gorospe M, Wang JY (2011). Regulation of cyclin-dependent kinase 4 translation through CUG-binding protein 1 and microRNA-222 by polyamines. Mol Biol Cell 22, 3055-3069.
    • (2011) Mol Biol Cell , vol.22 , pp. 3055-3069
    • Xiao, L.1    Cui, Y.H.2    Rao, J.N.3    Zou, T.4    Liu, L.5    Smith, A.6    Turner, D.J.7    Gorospe, M.8    Wang, J.Y.9
  • 42
    • 35848932765 scopus 로고    scopus 로고
    • Polyamines regulate the stability of activating transcription factor-2 mRNA through RNA-binding protein HuR in intestinal epithelial cells
    • Xiao L, Rao JN, Zou T, Liu L, Marasa BS, Chen J, Turner DJ, Zhou H, Gorospe M, Wang JY (2007). Polyamines regulate the stability of activating transcription factor-2 mRNA through RNA-binding protein HuR in intestinal epithelial cells. Mol Biol Cell 18, 4579-4590.
    • (2007) Mol Biol Cell , vol.18 , pp. 4579-4590
    • Xiao, L.1    Rao, J.N.2    Zou, T.3    Liu, L.4    Marasa, B.S.5    Chen, J.6    Turner, D.J.7    Zhou, H.8    Gorospe, M.9    Wang, J.Y.10
  • 43
    • 84855465218 scopus 로고    scopus 로고
    • Myeloid cell expression of the RNA-binding protein HuR protects mice from pathologic inflammation and colorectal carcinogenesis
    • Yiakouvaki A, Dimitriou M, Karakasiliotis I, Eftychi C, Theocharis S, Kontoyiannis DL (2012). Myeloid cell expression of the RNA-binding protein HuR protects mice from pathologic inflammation and colorectal carcinogenesis. J Clin Invest 122, 48-61.
    • (2012) J Clin Invest , vol.122 , pp. 48-61
    • Yiakouvaki, A.1    Dimitriou, M.2    Karakasiliotis, I.3    Eftychi, C.4    Theocharis, S.5    Kontoyiannis, D.L.6
  • 45
    • 65349120262 scopus 로고    scopus 로고
    • The mRNA binding proteins HuR and tristetraprolin regulate cyclooxygenase 2 expression during colon carcinogenesis
    • Young LE, Sanduja S, Bemis-Standoli K, Pena EA, Price RL, Dixon DA (2009). The mRNA binding proteins HuR and tristetraprolin regulate cyclooxygenase 2 expression during colon carcinogenesis. Gastroenterology 136, 1669-1679.
    • (2009) Gastroenterology , vol.136 , pp. 1669-1679
    • Young, L.E.1    Sanduja, S.2    Bemis-Standoli, K.3    Pena, E.A.4    Price, R.L.5    Dixon, D.A.6
  • 46
    • 84872291506 scopus 로고    scopus 로고
    • Competitive binding of CUGBP1 and HuR to occludin mRNA controls its translation and modulates epithelial barrier function
    • Yu TX, Rao JN, Zou T, Liu L, Xiao L, Ouyang M, Cao S, Gorospe M, Wang JY (2013). Competitive binding of CUGBP1 and HuR to occludin mRNA controls its translation and modulates epithelial barrier function. Mol Biol Cell 24, 85-99.
    • (2013) Mol Biol Cell , vol.24 , pp. 85-99
    • Yu, T.X.1    Rao, J.N.2    Zou, T.3    Liu, L.4    Xiao, L.5    Ouyang, M.6    Cao, S.7    Gorospe, M.8    Wang, J.Y.9
  • 47
    • 80455129693 scopus 로고    scopus 로고
    • Chk2-dependent HuR phosphorylation regulates occludin mRNA translation and epithelial barrier function
    • Yu TX, Wang PY, Rao JN, Zou T, Liu L, Xiao L, Gorospe M, Wang JY (2011). Chk2-dependent HuR phosphorylation regulates occludin mRNA translation and epithelial barrier function. Nucleic Acids Res 39, 8472-8487.
    • (2011) Nucleic Acids Res , vol.39 , pp. 8472-8487
    • Yu, T.X.1    Wang, P.Y.2    Rao, J.N.3    Zou, T.4    Liu, L.5    Xiao, L.6    Gorospe, M.7    Wang, J.Y.8
  • 51
    • 77957841913 scopus 로고    scopus 로고
    • Polyamines regulate the stability of JunD mRNA by modulating the competitive binding of its 3′ untranslated region to HuR and AUF1
    • Zou T, Rao JN, Liu L, Xiao L, Yu TX, Jiang P, Gorospe M, Wang JY (2010). Polyamines regulate the stability of JunD mRNA by modulating the competitive binding of its 3′ untranslated region to HuR and AUF1. Mol Cell Biol 30, 5021-5032.
    • (2010) Mol Cell Biol , vol.30 , pp. 5021-5032
    • Zou, T.1    Rao, J.N.2    Liu, L.3    Xiao, L.4    Yu, T.X.5    Jiang, P.6    Gorospe, M.7    Wang, J.Y.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.