메뉴 건너뛰기




Volumn 74, Issue 18, 2014, Pages 5322-5335

Intestinal epithelial HuR modulates distinct pathways of proliferation and apoptosis and attenuates small intestinal and colonic tumor development

Author keywords

[No Author keywords available]

Indexed keywords

HU ANTIGEN;

EID: 84907546688     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-14-0726     Document Type: Article
Times cited : (58)

References (45)
  • 1
    • 1842529308 scopus 로고    scopus 로고
    • Tissue distribution of AU-rich mRNA-binding proteins involved in regulation of mRNA decay
    • Lu JY, Schneider RJ. Tissue distribution of AU-rich mRNA-binding proteins involved in regulation of mRNA decay. J Biol Chem 2004;279:12974-9.
    • (2004) J Biol Chem , vol.279 , pp. 12974-12979
    • Lu, J.Y.1    Schneider, R.J.2
  • 3
    • 79960929333 scopus 로고    scopus 로고
    • Transcriptome-wide analysis of regulatory interactions of the RNA-binding protein HuR
    • Lebedeva S, Jens M, Theil K, Schwanhausser B, Selbach M, Landthaler M, et al. Transcriptome-wide analysis of regulatory interactions of the RNA-binding protein HuR. Mol Cell 2011;43:340-52.
    • (2011) Mol Cell , vol.43 , pp. 340-352
    • Lebedeva, S.1    Jens, M.2    Theil, K.3    Schwanhausser, B.4    Selbach, M.5    Landthaler, M.6
  • 4
  • 5
    • 0033933196 scopus 로고    scopus 로고
    • Differential expression and localization of the mRNA binding proteins, AU-rich element mRNA binding protein (AUF1) and Hu antigen R (HuR), in neoplastic lung tissue
    • Blaxall BC, Dwyer-Nield LD, Bauer AK, Bohlmeyer TJ, Malkinson AM, Port JD. Differential expression and localization of the mRNA binding proteins, AU-rich element mRNA binding protein (AUF1) and Hu antigen R (HuR), in neoplastic lung tissue. Mol Carcinog 2000;28:76-83.
    • (2000) Mol Carcinog , vol.28 , pp. 76-83
    • Blaxall, B.C.1    Dwyer-Nield, L.D.2    Bauer, A.K.3    Bohlmeyer, T.J.4    Malkinson, A.M.5    Port, J.D.6
  • 7
    • 27744520451 scopus 로고    scopus 로고
    • HuR: Post-transcriptional paths to malignancy
    • Lopez de Silanes I, Lal A, Gorospe M. HuR: post-transcriptional paths to malignancy. RNA Biol 2005;2:11-3.
    • (2005) RNA Biol , vol.2 , pp. 11-13
    • Lopez De Silanes, I.1    Lal, A.2    Gorospe, M.3
  • 8
    • 84883058417 scopus 로고    scopus 로고
    • HuR is a post-transcriptional regulator of core metabolic enzymes in pancreatic cancer
    • Burkhart RA, Pineda DM, Chand SN, Romeo C, Londin ER, Karoly ED, et al. HuR is a post-transcriptional regulator of core metabolic enzymes in pancreatic cancer. RNA Biol 2013;10:1312-23.
    • (2013) RNA Biol , vol.10 , pp. 1312-1323
    • Burkhart, R.A.1    Pineda, D.M.2    Chand, S.N.3    Romeo, C.4    Londin, E.R.5    Karoly, E.D.6
  • 9
    • 84893809652 scopus 로고    scopus 로고
    • Cytoplasmic expression of the ELAV-like protein HuR as a potential prognostic marker in esophageal squamous cell carcinoma
    • Zhang C, Xue G, Bi J, Geng M, Chu H, Guan Y, et al. Cytoplasmic expression of the ELAV-like protein HuR as a potential prognostic marker in esophageal squamous cell carcinoma. Tumour Biol 2014;35:73-80.
    • (2014) Tumour Biol , vol.35 , pp. 73-80
    • Zhang, C.1    Xue, G.2    Bi, J.3    Geng, M.4    Chu, H.5    Guan, Y.6
  • 10
    • 66349125085 scopus 로고    scopus 로고
    • The RNA-binding protein Elavl1/HuR is essential for placental branching morphogenesis and embryonic development
    • Katsanou V, Milatos S, Yiakouvaki A, Sgantzis N, Kotsoni A, Alexiou M, et al. The RNA-binding protein Elavl1/HuR is essential for placental branching morphogenesis and embryonic development. Mol Cell Biol 2009;29:2762-76.
    • (2009) Mol Cell Biol , vol.29 , pp. 2762-2776
    • Katsanou, V.1    Milatos, S.2    Yiakouvaki, A.3    Sgantzis, N.4    Kotsoni, A.5    Alexiou, M.6
  • 11
    • 72849128981 scopus 로고    scopus 로고
    • Essential role of the RNA-binding protein HuR in progenitor cell survival in mice
    • Ghosh M, Aguila HL, Michaud J, Ai Y, Wu MT, Hemmes A, et al. Essential role of the RNA-binding protein HuR in progenitor cell survival in mice. J Clin Invest 2009;119:3530-43.
    • (2009) J Clin Invest , vol.119 , pp. 3530-3543
    • Ghosh, M.1    Aguila, H.L.2    Michaud, J.3    Ai, Y.4    Wu, M.T.5    Hemmes, A.6
  • 12
    • 84855465218 scopus 로고    scopus 로고
    • Myeloid cell expression of the RNA-binding protein HuR protects mice from pathologic inflammation and colorectal carcinogenesis
    • Yiakouvaki A, Dimitriou M, Karakasiliotis I, Eftychi C, Theocharis S, Kontoyiannis DL. Myeloid cell expression of the RNA-binding protein HuR protects mice from pathologic inflammation and colorectal carcinogenesis. J Clin Invest 2012;122:48-61.
    • (2012) J Clin Invest , vol.122 , pp. 48-61
    • Yiakouvaki, A.1    Dimitriou, M.2    Karakasiliotis, I.3    Eftychi, C.4    Theocharis, S.5    Kontoyiannis, D.L.6
  • 14
    • 0031705644 scopus 로고    scopus 로고
    • Marked reduction in bile acid synthesis in cholesterol 7alpha-hydroxylasedeficient mice does not lead to diminished tissue cholesterol turnover or to hypercholesterolemia
    • Schwarz M, Russell DW, Dietschy JM, Turley SD. Marked reduction in bile acid synthesis in cholesterol 7alpha-hydroxylasedeficient mice does not lead to diminished tissue cholesterol turnover or to hypercholesterolemia. J Lipid Res 1998;39:1833-43.
    • (1998) J Lipid Res , vol.39 , pp. 1833-1843
    • Schwarz, M.1    Russell, D.W.2    Dietschy, J.M.3    Turley, S.D.4
  • 15
    • 0020508974 scopus 로고
    • General methods for the analysis of metabolic profiles of bile acids and related compounds in feces
    • Setchell KD, Lawson AM, Tanida N, Sjovall J. General methods for the analysis of metabolic profiles of bile acids and related compounds in feces. J Lipid Res 1983;24:1085-100.
    • (1983) J Lipid Res , vol.24 , pp. 1085-1100
    • Setchell, K.D.1    Lawson, A.M.2    Tanida, N.3    Sjovall, J.4
  • 16
    • 78149398073 scopus 로고    scopus 로고
    • Musashi 1-positive cells derived from mouse embryonic stem cells can differentiate into neural and intestinal epithelial-like cells in vivo
    • Lan SY, Yu T, Xia ZS, Yuan YH, Shi L, Lin Y, et al. Musashi 1-positive cells derived from mouse embryonic stem cells can differentiate into neural and intestinal epithelial-like cells in vivo. Cell Biol Int 2010;34:1171-80.
    • (2010) Cell Biol Int , vol.34 , pp. 1171-1180
    • Lan, S.Y.1    Yu, T.2    Xia, Z.S.3    Yuan, Y.H.4    Shi, L.5    Lin, Y.6
  • 17
    • 84863170142 scopus 로고    scopus 로고
    • The role of Hes genes in intestinal development, homeostasis and tumor formation
    • Ueo T, Imayoshi I, Kobayashi T, Ohtsuka T, Seno H, Nakase H, et al. The role of Hes genes in intestinal development, homeostasis and tumor formation. Development 2012;139:1071-82.
    • (2012) Development , vol.139 , pp. 1071-1082
    • Ueo, T.1    Imayoshi, I.2    Kobayashi, T.3    Ohtsuka, T.4    Seno, H.5    Nakase, H.6
  • 18
    • 84855987629 scopus 로고    scopus 로고
    • The oncogenic RNA-binding protein Musashi1 is regulated by HuR via mRNA translation and stability in glioblastoma cells
    • Vo DT, Abdelmohsen K, Martindale JL, Qiao M, Tominaga K, Burton TL, et al. The oncogenic RNA-binding protein Musashi1 is regulated by HuR via mRNA translation and stability in glioblastoma cells. Mol Cancer Res 2012;10:143-55.
    • (2012) Mol Cancer Res , vol.10 , pp. 143-155
    • Vo, D.T.1    Abdelmohsen, K.2    Martindale, J.L.3    Qiao, M.4    Tominaga, K.5    Burton, T.L.6
  • 21
    • 84871789026 scopus 로고    scopus 로고
    • Restriction of intestinal stem cell expansion and the regenerative response by YAP
    • Barry ER, Morikawa T, Butler BL, Shrestha K, de la Rosa R, Yan KS, et al. Restriction of intestinal stem cell expansion and the regenerative response by YAP. Nature 2013;493:106-10.
    • (2013) Nature , vol.493 , pp. 106-110
    • Barry, E.R.1    Morikawa, T.2    Butler, B.L.3    Shrestha, K.4    De La Rosa, R.5    Yan, K.S.6
  • 22
    • 34547651351 scopus 로고    scopus 로고
    • Posttranscriptional orchestration of an anti-apoptotic program by HuR
    • Abdelmohsen K, Lal A, Kim HH, Gorospe M. Posttranscriptional orchestration of an anti-apoptotic program by HuR. Cell Cycle 2007;6:1288-92.
    • (2007) Cell Cycle , vol.6 , pp. 1288-1292
    • Abdelmohsen, K.1    Lal, A.2    Kim, H.H.3    Gorospe, M.4
  • 23
    • 79952754428 scopus 로고    scopus 로고
    • Global dissociation of HuR-mRNA complexes promotes cell survival after ionizing radiation
    • Masuda K, Abdelmohsen K, Kim MM, Srikantan S, Lee EK, Tominaga K, et al. Global dissociation of HuR-mRNA complexes promotes cell survival after ionizing radiation. EMBO J 2011;30:1040-53.
    • (2011) EMBO J , vol.30 , pp. 1040-1053
    • Masuda, K.1    Abdelmohsen, K.2    Kim, M.M.3    Srikantan, S.4    Lee, E.K.5    Tominaga, K.6
  • 25
    • 0035213198 scopus 로고    scopus 로고
    • Altered expression of the mRNA stability factor HuR promotes cyclooxygenase-2 expression in colon cancer cells
    • Dixon DA, Tolley ND, King PH, Nabors LB, McIntyre TM, Zimmerman GA, et al. Altered expression of the mRNA stability factor HuR promotes cyclooxygenase-2 expression in colon cancer cells. J Clin Invest 2001;108:1657-65.
    • (2001) J Clin Invest , vol.108 , pp. 1657-1665
    • Dixon, D.A.1    Tolley, N.D.2    King, P.H.3    Nabors, L.B.4    McIntyre, T.M.5    Zimmerman, G.A.6
  • 26
    • 79958862745 scopus 로고    scopus 로고
    • The RNA-binding protein HuR stabilizes survivin mRNA in human oesophageal epithelial cells
    • Donahue JM, Chang ET, Xiao L, Wang PY, Rao JN, Turner DJ, et al. The RNA-binding protein HuR stabilizes survivin mRNA in human oesophageal epithelial cells. Biochem J 2011;437:89-96.
    • (2011) Biochem J , vol.437 , pp. 89-96
    • Donahue, J.M.1    Chang, E.T.2    Xiao, L.3    Wang, P.Y.4    Rao, J.N.5    Turner, D.J.6
  • 27
    • 84871014558 scopus 로고    scopus 로고
    • Apoptotic-induced cleavage shifts HuR from being a promoter of survival to an activator of caspase-mediated apoptosis
    • von Roretz C, Lian XJ, Macri AM, Punjani N, Clair E, Drouin O, et al. Apoptotic-induced cleavage shifts HuR from being a promoter of survival to an activator of caspase-mediated apoptosis. Cell Death Differ 2013;20:154-68.
    • (2013) Cell Death Differ , vol.20 , pp. 154-168
    • Von Roretz, C.1    Lian, X.J.2    Macri, A.M.3    Punjani, N.4    Clair, E.5    Drouin, O.6
  • 28
    • 81155160856 scopus 로고    scopus 로고
    • Hu antigen R and tristetraprolin: Counter-regulators of rat apical sodium-dependent bile acid transporter by way of effects on messenger RNA stability
    • Chen F, Shyu AB, Shneider BL. Hu antigen R and tristetraprolin: counter-regulators of rat apical sodium-dependent bile acid transporter by way of effects on messenger RNA stability. Hepatology 2011;54:1371-8.
    • (2011) Hepatology , vol.54 , pp. 1371-1378
    • Chen, F.1    Shyu, A.B.2    Shneider, B.L.3
  • 29
  • 30
    • 48749087514 scopus 로고    scopus 로고
    • Bile acid transporters in health and disease
    • Kosters A, Karpen SJ. Bile acid transporters in health and disease. Xenobiotica 2008;38:1043-71.
    • (2008) Xenobiotica , vol.38 , pp. 1043-1071
    • Kosters, A.1    Karpen, S.J.2
  • 31
    • 84874105786 scopus 로고    scopus 로고
    • Inflammation and colorectal cancer: Colitis-associated neoplasia
    • Grivennikov SI. Inflammation and colorectal cancer: colitis-associated neoplasia. Semin Immunopathol 2013;35:229-44.
    • (2013) Semin Immunopathol , vol.35 , pp. 229-244
    • Grivennikov, S.I.1
  • 32
    • 79952996039 scopus 로고    scopus 로고
    • Inflammatory cytokines in cancer: Tumour necrosis factor and interleukin 6 take the stage
    • Grivennikov SI, Karin M. Inflammatory cytokines in cancer: tumour necrosis factor and interleukin 6 take the stage. Ann Rheum Dis 2011;70 Suppl 1:i104-8.
    • (2011) Ann Rheum Dis , vol.70 , pp. i104-i108
    • Grivennikov, S.I.1    Karin, M.2
  • 33
    • 43149126092 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor-A and mRNA stability factor HuR in human meningiomas
    • Sakuma T, Nakagawa T, Ido K, Takeuchi H, Sato K, Kubota T. Expression of vascular endothelial growth factor-A and mRNA stability factor HuR in human meningiomas. J Neurooncol 2008;88:143-55.
    • (2008) J Neurooncol , vol.88 , pp. 143-155
    • Sakuma, T.1    Nakagawa, T.2    Ido, K.3    Takeuchi, H.4    Sato, K.5    Kubota, T.6
  • 34
    • 0037134484 scopus 로고    scopus 로고
    • A 40-bp RNA element that mediates stabilization of vascular endothelial growth factor mRNA by HuR
    • Goldberg-Cohen I, Furneauxb H, Levy AP. A 40-bp RNA element that mediates stabilization of vascular endothelial growth factor mRNA by HuR. J Biol Chem 2002;277:13635-40.
    • (2002) J Biol Chem , vol.277 , pp. 13635-13640
    • Goldberg-Cohen, I.1    Furneauxb, H.2    Levy, A.P.3
  • 36
    • 84874027192 scopus 로고    scopus 로고
    • Antagonistic function of the RNA-binding protein HuR and miR-200b in post-transcriptional regulation of vascular endothelial growth factor-A expression and angiogenesis
    • Chang SH, Lu YC, Li X, Hsieh WY, Xiong Y, Ghosh M, et al. Antagonistic function of the RNA-binding protein HuR and miR-200b in post-transcriptional regulation of vascular endothelial growth factor-A expression and angiogenesis. J Biol Chem 2013;288:4908-21.
    • (2013) J Biol Chem , vol.288 , pp. 4908-4921
    • Chang, S.H.1    Lu, Y.C.2    Li, X.3    Hsieh, W.Y.4    Xiong, Y.5    Ghosh, M.6
  • 37
    • 79952202070 scopus 로고    scopus 로고
    • Stem cell marker olfactomedin 4: Critical appraisal of its characteristics and role in tumorigenesis
    • Grover PK, Hardingham JE, Cummins AG. Stem cell marker olfactomedin 4: critical appraisal of its characteristics and role in tumorigenesis. Cancer Metastasis Rev 2010;29:761-75.
    • (2010) Cancer Metastasis Rev , vol.29 , pp. 761-775
    • Grover, P.K.1    Hardingham, J.E.2    Cummins, A.G.3
  • 38
    • 33846657603 scopus 로고    scopus 로고
    • Specific overexpression of OLFM4 (GW112/HGC-1) mRNA in colon, breast and lung cancer tissues detected using quantitative analysis
    • Koshida S, Kobayashi D, Moriai R, Tsuji N, Watanabe N. Specific overexpression of OLFM4 (GW112/HGC-1) mRNA in colon, breast and lung cancer tissues detected using quantitative analysis. Cancer Sci 2007;98:315-20.
    • (2007) Cancer Sci , vol.98 , pp. 315-320
    • Koshida, S.1    Kobayashi, D.2    Moriai, R.3    Tsuji, N.4    Watanabe, N.5
  • 39
    • 85027955541 scopus 로고    scopus 로고
    • Olfactomedin 4 suppresses tumor growth and metastasis of mouse melanoma cells through downregulation of integrin and MMP genes
    • Park KS, Kim KK, Piao ZH, Kim MK, Lee HJ, Kim YC, et al. Olfactomedin 4 suppresses tumor growth and metastasis of mouse melanoma cells through downregulation of integrin and MMP genes. Mol Cells 2012;34:555-61.
    • (2012) Mol Cells , vol.34 , pp. 555-561
    • Park, K.S.1    Kim, K.K.2    Piao, Z.H.3    Kim, M.K.4    Lee, H.J.5    Kim, Y.C.6
  • 40
    • 84900302704 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition induces endoplasmic-reticulum-stress response in human colorectal tumor cells
    • Zeindl-Eberhart E, Brandl L, Liebmann S, Ormanns S, Scheel SK, Brabletz T, et al. Epithelial-mesenchymal transition induces endoplasmic-reticulum-stress response in human colorectal tumor cells. PLoS ONE 2014;9:e87386.
    • (2014) PLoS ONE , vol.9 , pp. e87386
    • Zeindl-Eberhart, E.1    Brandl, L.2    Liebmann, S.3    Ormanns, S.4    Scheel, S.K.5    Brabletz, T.6
  • 41
    • 84898961798 scopus 로고    scopus 로고
    • PHLPP is a negative regulator of RAF1, which reduces colorectal cancer cell motility and prevents tumor progression in mice
    • e1-10
    • Li X, Stevens PD, Liu J, Yang H, Wang W, Wang C, et al. PHLPP is a negative regulator of RAF1, which reduces colorectal cancer cell motility and prevents tumor progression in mice. Gastroenterology 2014;146:1301-12. e1-10.
    • (2014) Gastroenterology , vol.146 , pp. 1301-1312
    • Li, X.1    Stevens, P.D.2    Liu, J.3    Yang, H.4    Wang, W.5    Wang, C.6
  • 42
    • 84899476970 scopus 로고    scopus 로고
    • Dynamic switch between two adhesion phenotypes in colorectal cancer cells
    • Geng Y, Chandrasekaran S, Agastin S, Li J, King MR. Dynamic switch between two adhesion phenotypes in colorectal cancer cells. Cell Mol Bioeng 2014;7:35-44.
    • (2014) Cell Mol Bioeng , vol.7 , pp. 35-44
    • Geng, Y.1    Chandrasekaran, S.2    Agastin, S.3    Li, J.4    King, M.R.5
  • 43
    • 0029792840 scopus 로고    scopus 로고
    • Comparative analysis of the ontogeny of a sodium-dependent bile acid transporter in rat kidney and ileum
    • Christie DM, Dawson PA, Thevananther S, Shneider BL. Comparative analysis of the ontogeny of a sodium-dependent bile acid transporter in rat kidney and ileum. Am J Physiol 1996;271(2 Pt 1):G377-85.
    • (1996) Am J Physiol , vol.271 , Issue.2 , pp. G377-G385
    • Christie, D.M.1    Dawson, P.A.2    Thevananther, S.3    Shneider, B.L.4
  • 44
    • 54849405345 scopus 로고    scopus 로고
    • Expressionof vascular endothelial growth factor-A and mRNA stability factor HuR in human astrocytic tumors
    • Ido K, Nakagawa T, Sakuma T, Takeuchi H, Sato K, Kubota T. Expressionof vascular endothelial growth factor-A and mRNA stability factor HuR in human astrocytic tumors. Neuropathology 2008;28:604-11.
    • (2008) Neuropathology , vol.28 , pp. 604-611
    • Ido, K.1    Nakagawa, T.2    Sakuma, T.3    Takeuchi, H.4    Sato, K.5    Kubota, T.6
  • 45
    • 33748291762 scopus 로고    scopus 로고
    • Post-transcriptional regulation of vascular endothelial growth factor: Implications for tumor angiogenesis
    • Yoo PS, Mulkeen AL, Cha CH. Post-transcriptional regulation of vascular endothelial growth factor: implications for tumor angiogenesis. World J Gastroenterol 2006;12:4937-42.
    • (2006) World J Gastroenterol , vol.12 , pp. 4937-4942
    • Yoo, P.S.1    Mulkeen, A.L.2    Cha, C.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.