Structural insights into the human RyR2 N-terminal region involved in cardiac arrhythmias

Acta Crystallographica Section D: Biological Crystallography

Volumn 70, Issue 11, 2014, Pages 2897-2912

  Borko, ̗ubomír ^a   Bauerová Hlinková, Vladena ^a   Hostinová, Eva ^a   Gašperík, Juraj ^a   Beck, Konrad ^b   Lai, F Anthony ^c   Zahradníková, Alexandra ^a,d   Ševčík, Jozef ^a  

^a Institute of Molecular Biology Slovak Academy of Sciences   (Slovakia)

^b CARDIFF UNIVERSITY   (United Kingdom)

^c CARDIFF UNIVERSITY SCHOOL OF MEDICINE   (United Kingdom)

^d INSTITUTE OF MOLECULAR PHYSIOLOGY AND GENETICS   (Slovakia)

Author keywords

arrhythmogenic mutations; human ryanodine receptor 2; molecular modelling; phosphoprotein phosphatase I binding site; X ray and SAXS structure

Indexed keywords

CHLORIDE; RYANODINE RECEPTOR;

AMINO ACID SEQUENCE; ANIMAL; BINDING SITE; CHEMISTRY; GENETICS; HEART ARRHYTHMIA; HUMAN; METABOLISM; MOLECULAR DOCKING; MOLECULAR GENETICS; MOUSE; MUTATION; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE; SEQUENCE ALIGNMENT; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; ANIMALS; ARRHYTHMIAS, CARDIAC; BINDING SITES; CHLORIDES; CRYSTALLOGRAPHY, X-RAY; HUMANS; MICE; MOLECULAR DOCKING SIMULATION; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SEQUENCE ALIGNMENT;

EID: 84908614054     PISSN: 09074449     EISSN: 13990047     Source Type: Journal    
DOI: 10.1107/S1399004714020343     Document Type: Article

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