-
1
-
-
84864765533
-
Microglia and mast cells: Two tracks on the road to neuroinflammation
-
Skaper, S. D., Giusti, P., and Facci, L. (2012) Microglia and mast cells: two tracks on the road to neuroinflammation. FASEB J. 26, 3103-3117.
-
(2012)
FASEB J.
, vol.26
, pp. 3103-3117
-
-
Skaper, S.D.1
Giusti, P.2
Facci, L.3
-
2
-
-
0023789193
-
Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains
-
McGeer, P. L., Itagaki, S., Boyes, B. E., and McGeer, E. G. (1988) Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains. Neurology 38, 1285-1291.
-
(1988)
Neurology
, vol.38
, pp. 1285-1291
-
-
McGeer, P.L.1
Itagaki, S.2
Boyes, B.E.3
McGeer, E.G.4
-
3
-
-
0035152836
-
Immune function of microglia
-
Aloisi, F. (2001) Immune function of microglia. Glia 36, 165-179.
-
(2001)
Glia
, vol.36
, pp. 165-179
-
-
Aloisi, F.1
-
4
-
-
30444459031
-
The role of inflammation in CNS injury and disease
-
Lucas, S. M., Rothwell, N. J., and Gibson, R. M. (2006) The role of inflammation in CNS injury and disease. Br. J. Pharmacol. 147 (Suppl 1), S232-240.
-
(2006)
Br. J. Pharmacol.
, vol.147
, pp. S232-S240
-
-
Lucas, S.M.1
Rothwell, N.J.2
Gibson, R.M.3
-
5
-
-
0029760138
-
Molecular mechanisms of microglial activation
-
Zielasek, J., and Hartung, H. P. (1996) Molecular mechanisms of microglial activation. Adv. Neuroimmunol. 6, 191-122.
-
(1996)
Adv. Neuroimmunol.
, vol.6
, pp. 191-1122
-
-
Zielasek, J.1
Hartung, H.P.2
-
6
-
-
62949112658
-
Periventricular white matter damage in the hypoxic neonatal brain: Role of microglial cells
-
Kaur, C., and Ling, E. A. (2009) Periventricular white matter damage in the hypoxic neonatal brain: role of microglial cells. Prog. Neurobiol. 87, 264-280.
-
(2009)
Prog. Neurobiol.
, vol.87
, pp. 264-280
-
-
Kaur, C.1
Ling, E.A.2
-
7
-
-
0033567065
-
Enzymatic function of nitric oxide synthases
-
Andrew, P. J., and Mayer, B. (1999) Enzymatic function of nitric oxide synthases. Cardiovasc. Res. 43, 521-531.
-
(1999)
Cardiovasc. Res.
, vol.43
, pp. 521-531
-
-
Andrew, P.J.1
Mayer, B.2
-
8
-
-
33744984393
-
Pharmacological strategies for the regulation of inducible nitric oxide synthase: Neurodegenerative versus neuroprotective mechanisms
-
Pannu, R., and Singh, I. (2006) Pharmacological strategies for the regulation of inducible nitric oxide synthase: Neurodegenerative versus neuroprotective mechanisms. Neurochem. Int. 49, 170-182.
-
(2006)
Neurochem. Int.
, vol.49
, pp. 170-182
-
-
Pannu, R.1
Singh, I.2
-
9
-
-
0029841018
-
Measurement of nitric oxide and peroxynitrite generation in the postischemic heart - Evidence for peroxynitrite-mediated reperfusion injury
-
Wang, P. H., and Zweier, J. L. (1996) Measurement of nitric oxide and peroxynitrite generation in the postischemic heart - Evidence for peroxynitrite-mediated reperfusion injury. J. Biol. Chem. 271, 29223-29230.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 29223-29230
-
-
Wang, P.H.1
Zweier, J.L.2
-
10
-
-
0036244508
-
Nitric oxide and peroxynitrite interactions with mitochondria
-
Radi, R., Cassina, A., and Hodara, R. (2002) Nitric oxide and peroxynitrite interactions with mitochondria. Biol. Chem. 383, 401-409.
-
(2002)
Biol. Chem.
, vol.383
, pp. 401-409
-
-
Radi, R.1
Cassina, A.2
Hodara, R.3
-
11
-
-
34548726106
-
TNF-alpha inhibition as a treatment strategy for neurodegenerative disorders: New drug candidates and targets
-
Tweedie, D., Sambamurti, K., and Greig, N. H. (2007) TNF-alpha inhibition as a treatment strategy for neurodegenerative disorders: New drug candidates and targets. Curr. Alzheimer Res. 4, 378-385.
-
(2007)
Curr. Alzheimer Res.
, vol.4
, pp. 378-385
-
-
Tweedie, D.1
Sambamurti, K.2
Greig, N.H.3
-
12
-
-
84860122734
-
Tumor Necrosis Factor-alpha and the Roles it Plays in Homeostatic and Degenerative Processes Within the Central Nervous System
-
Montgomery, S. L., and Bowers, W. J. (2012) Tumor Necrosis Factor-alpha and the Roles it Plays in Homeostatic and Degenerative Processes Within the Central Nervous System. J. Neuroimmune Pharmacol. 7, 42-59.
-
(2012)
J. Neuroimmune Pharmacol.
, vol.7
, pp. 42-59
-
-
Montgomery, S.L.1
Bowers, W.J.2
-
13
-
-
0036949091
-
Local neuroinflammation and the progression of Alzheimer's disease
-
McGeer, P. L., and McGeer, E. G. (2002) Local neuroinflammation and the progression of Alzheimer's disease. J. Neuro Virol. 8, 529-538.
-
(2002)
J. Neuro Virol.
, vol.8
, pp. 529-538
-
-
McGeer, P.L.1
McGeer, E.G.2
-
14
-
-
0032557738
-
Inhibition of TNFalpha attenuates infarct volume and ICAM-1 expression in ischemic mouse brain
-
Yang, G. Y., Gong, C., Qin, Z., Ye, W., Mao, Y., and Bertz, A. L. (1998) Inhibition of TNFalpha attenuates infarct volume and ICAM-1 expression in ischemic mouse brain. NeuroReport 9, 2131-2134.
-
(1998)
NeuroReport
, vol.9
, pp. 2131-2134
-
-
Yang, G.Y.1
Gong, C.2
Qin, Z.3
Ye, W.4
Mao, Y.5
Bertz, A.L.6
-
15
-
-
0033512004
-
Inflammatory mediators and stroke: New opportunities for novel therapeutics
-
Barone, F. C., and Feuerstein, G. Z. (1999) Inflammatory mediators and stroke: new opportunities for novel therapeutics. J. Cereb. Blood Flow Metab. 19, 819-834.
-
(1999)
J. Cereb. Blood Flow Metab.
, vol.19
, pp. 819-834
-
-
Barone, F.C.1
Feuerstein, G.Z.2
-
16
-
-
0034281374
-
Cerebral ischemia and seizures induce tyrosine phosphorylation of PYK2 in neurons and microglial cells
-
Tian, D., Litvak, V., and Lev, S. (2000) Cerebral ischemia and seizures induce tyrosine phosphorylation of PYK2 in neurons and microglial cells. J. Neurosci. 20, 6478-6487.
-
(2000)
J. Neurosci.
, vol.20
, pp. 6478-6487
-
-
Tian, D.1
Litvak, V.2
Lev, S.3
-
17
-
-
0031594354
-
Activation of p38(MAPK) in microglia after ischemia
-
Walton, K. M., DiRocco, R., Bartlett, B. A., Koury, E., Marcy, V. R., Jarvis, B., Schaefer, E. M., and Bhat, R. V. (1998) Activation of p38(MAPK) in microglia after ischemia. J. Neurochem. 70, 1764-1767.
-
(1998)
J. Neurochem.
, vol.70
, pp. 1764-1767
-
-
Walton, K.M.1
DiRocco, R.2
Bartlett, B.A.3
Koury, E.4
Marcy, V.R.5
Jarvis, B.6
Schaefer, E.M.7
Bhat, R.V.8
-
18
-
-
84882866377
-
NOSH-aspirin (NBS-1120), a novel nitric oxide and hydrogen sulfide releasing hybrid, attenuates neuroinflammation induced by microglial and astrocytic activation: A new candidate for treatment of neurodegenerative disorders
-
Lee, M., McGeer, E., Kodela, R., Kashfi, K., and McGeer, P. L. (2013) NOSH-aspirin (NBS-1120), a novel nitric oxide and hydrogen sulfide releasing hybrid, attenuates neuroinflammation induced by microglial and astrocytic activation: A new candidate for treatment of neurodegenerative disorders. Glia 61, 1724-1734.
-
(2013)
Glia
, vol.61
, pp. 1724-1734
-
-
Lee, M.1
McGeer, E.2
Kodela, R.3
Kashfi, K.4
McGeer, P.L.5
-
19
-
-
0035895803
-
SB 239063, a novel p38 inhibitor, attenuates early neuronal injury following ischemia
-
Legos, J. J., Erhardt, J. A., White, R. F., Lenhard, S. C., Chandra, S., Parsons, A. A., Tuma, R. F., and Barone, F. C. (2001) SB 239063, a novel p38 inhibitor, attenuates early neuronal injury following ischemia. Brain Res. 892, 70-77.
-
(2001)
Brain Res.
, vol.892
, pp. 70-77
-
-
Legos, J.J.1
Erhardt, J.A.2
White, R.F.3
Lenhard, S.C.4
Chandra, S.5
Parsons, A.A.6
Tuma, R.F.7
Barone, F.C.8
-
20
-
-
0035142857
-
SB 239063, a second-generation p38 mitogen-activated protein kinase inhibitor, reduces brain injury and neurological deficits in cerebral focal ischemia
-
Barone, F. C., Irving, E. A., Ray, A. M., Lee, J. C., Kassis, S., Kumar, S., Badger, A. M., White, R. F., McVey, M. J., Legos, J. J., Erhardt, J. A., Nelson, A. H., Ohlstein, E. H., Hunter, A. J., Ward, K., Smith, B. R., Adams, J. L., and Parsons, A. A. (2001) SB 239063, a second-generation p38 mitogen-activated protein kinase inhibitor, reduces brain injury and neurological deficits in cerebral focal ischemia. J. Pharmacol. Exp. Ther. 296, 312-321.
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.296
, pp. 312-321
-
-
Barone, F.C.1
Irving, E.A.2
Ray, A.M.3
Lee, J.C.4
Kassis, S.5
Kumar, S.6
Badger, A.M.7
White, R.F.8
McVey, M.J.9
Legos, J.J.10
Erhardt, J.A.11
Nelson, A.H.12
Ohlstein, E.H.13
Hunter, A.J.14
Ward, K.15
Smith, B.R.16
Adams, J.L.17
Parsons, A.A.18
-
21
-
-
81155151818
-
Role of the mTOR Pathway in LPS-Activated Monocytes: Influence of Hypertonic Saline
-
Schaeffer, V., Arbabi, S., Garcia, I. A., Knoll, M. L., Cuschieri, J., Bulger, E. M., and Maier, R. V. (2011) Role of the mTOR Pathway in LPS-Activated Monocytes: Influence of Hypertonic Saline. J. Surg. Res. 171, 769-776.
-
(2011)
J. Surg. Res.
, vol.171
, pp. 769-776
-
-
Schaeffer, V.1
Arbabi, S.2
Garcia, I.A.3
Knoll, M.L.4
Cuschieri, J.5
Bulger, E.M.6
Maier, R.V.7
-
22
-
-
33846863589
-
Nitric oxide and peroxynitrite in health and disease
-
Pacher, P., Beckman, J. S., and Liaudet, L. (2007) Nitric oxide and peroxynitrite in health and disease. Physiol. Rev. 87, 315-424.
-
(2007)
Physiol. Rev.
, vol.87
, pp. 315-424
-
-
Pacher, P.1
Beckman, J.S.2
Liaudet, L.3
-
23
-
-
33847644971
-
The inflammatory response in stroke
-
Wang, Q., Tang, X. N., and Yenari, M. A. (2007) The inflammatory response in stroke. J. Neuroimmunol. 184, 53-68.
-
(2007)
J. Neuroimmunol.
, vol.184
, pp. 53-68
-
-
Wang, Q.1
Tang, X.N.2
Yenari, M.A.3
-
24
-
-
84924948342
-
Characterisation of protein kinases targeting p65 NF-KB phosphorylation and transactivation
-
Buss, H., Schmitz, L., Dorrie, A., Resch, K., and Kracht, M. (2002) Characterisation of protein kinases targeting p65 NF-KB phosphorylation and transactivation. Naunyn-Schmiedeberg's Arch. Pharmacol. 365, R56-R56.
-
(2002)
Naunyn-Schmiedeberg's Arch. Pharmacol.
, vol.365
, pp. R56-R56
-
-
Buss, H.1
Schmitz, L.2
Dorrie, A.3
Resch, K.4
Kracht, M.5
-
25
-
-
77957774860
-
Who is referred to neurology clinics? The diagnoses made in 3781 new patients
-
Stone, J., Carson, A., Duncan, R., Roberts, R., Warlow, C., Hibberd, C., Coleman, R., Cull, R., Murray, G., Pelosi, A., Cavanagh, J., Matthews, K., Goldbeck, R., Smyth, R., Walker, J., and Sharpe, M. (2010) Who is referred to neurology clinics? The diagnoses made in 3781 new patients. Clin. Neurol. Neurosurg. 112, 747-751.
-
(2010)
Clin. Neurol. Neurosurg.
, vol.112
, pp. 747-751
-
-
Stone, J.1
Carson, A.2
Duncan, R.3
Roberts, R.4
Warlow, C.5
Hibberd, C.6
Coleman, R.7
Cull, R.8
Murray, G.9
Pelosi, A.10
Cavanagh, J.11
Matthews, K.12
Goldbeck, R.13
Smyth, R.14
Walker, J.15
Sharpe, M.16
-
26
-
-
18744403704
-
Effect of Eucommia ulmoides on systolic blood pressure in the spontaneous hypertensive rat
-
Lang, C., Liu, Z., Taylor, H. W., and Baker, D. G. (2005) Effect of Eucommia ulmoides on systolic blood pressure in the spontaneous hypertensive rat. Am. J. Chin. Med. 33, 215-230.
-
(2005)
Am. J. Chin. Med.
, vol.33
, pp. 215-230
-
-
Lang, C.1
Liu, Z.2
Taylor, H.W.3
Baker, D.G.4
-
27
-
-
0015366232
-
Alteration of the course of hypertension in the spontaneously hypertensive rat
-
Freis, E. D., Ragan, D., Pillsbury, H., 3rd, and Mathews, M. (1972) Alteration of the course of hypertension in the spontaneously hypertensive rat. Circ. Res. 31, 1-7.
-
(1972)
Circ. Res.
, vol.31
, pp. 1-7
-
-
Freis, E.D.1
Ragan, D.2
Pillsbury, H.3
Mathews, M.4
-
28
-
-
84863244479
-
Eucommia ulmoides bark protects against renal injury in cadmium-challenged rats
-
Liu, E., Han, L., Wang, J., He, W., Shang, H., Gao, X., and Wang, T. (2012) Eucommia ulmoides bark protects against renal injury in cadmium-challenged rats. J. Med. Food 15, 307-314.
-
(2012)
J. Med. Food
, vol.15
, pp. 307-314
-
-
Liu, E.1
Han, L.2
Wang, J.3
He, W.4
Shang, H.5
Gao, X.6
Wang, T.7
-
29
-
-
33846235930
-
Eucommia ulmoides Oliver leaf extract increases endogenous antioxidant activity in type 2 diabetic mice
-
Park, S. A., Choi, M. S., Jung, U. J., Kim, M. J., Kim, D. J., Park, H. M., Park, Y. B., and Lee, M. K. (2006) Eucommia ulmoides Oliver leaf extract increases endogenous antioxidant activity in type 2 diabetic mice. J. Med. Food 9, 474-479.
-
(2006)
J. Med. Food
, vol.9
, pp. 474-479
-
-
Park, S.A.1
Choi, M.S.2
Jung, U.J.3
Kim, M.J.4
Kim, D.J.5
Park, H.M.6
Park, Y.B.7
Lee, M.K.8
-
30
-
-
33845699846
-
An update on pharmacological approaches to neurodegenerative diseases
-
Scatena, R., Martorana, G. E., Bottoni, P., Botta, G., Pastore, P., and Giardina, B. (2007) An update on pharmacological approaches to neurodegenerative diseases. Expert Opin. Invest. Drugs 16, 59-72.
-
(2007)
Expert Opin. Invest. Drugs
, vol.16
, pp. 59-72
-
-
Scatena, R.1
Martorana, G.E.2
Bottoni, P.3
Botta, G.4
Pastore, P.5
Giardina, B.6
-
31
-
-
31144450053
-
Current pharmacotherapy for Alzheimer's disease
-
Lleo, A., Greenberg, S. M., and Growdon, J. H. (2006) Current pharmacotherapy for Alzheimer's disease. Annu. Rev. Med. 57, 513-533.
-
(2006)
Annu. Rev. Med.
, vol.57
, pp. 513-533
-
-
Lleo, A.1
Greenberg, S.M.2
Growdon, J.H.3
-
32
-
-
63049091897
-
-
Human Press Inc., Clifton, NJ
-
Sarker, S. D., Latif, Z., and Gray, A. I. (2006) Natural Products Isolation, Human Press Inc., Clifton, NJ.
-
(2006)
Natural Products Isolation
-
-
Sarker, S.D.1
Latif, Z.2
Gray, A.I.3
-
33
-
-
70350712465
-
Isolation of antifungal compounds from Gardenia jasminoides
-
Lelono, R. A., Tachibana, S., and Itoh, K. (2009) Isolation of antifungal compounds from Gardenia jasminoides. Pak. J. Biol. Sci. 12, 949-956.
-
(2009)
Pak. J. Biol. Sci.
, vol.12
, pp. 949-956
-
-
Lelono, R.A.1
Tachibana, S.2
Itoh, K.3
-
34
-
-
16344371938
-
Synthesis and characterization of a novel chitosan-gelatin bioconjugate with fluorescence emission
-
Mi, F. L. (2005) Synthesis and characterization of a novel chitosan-gelatin bioconjugate with fluorescence emission. Biomacromolecules 6, 975-987.
-
(2005)
Biomacromolecules
, vol.6
, pp. 975-987
-
-
Mi, F.L.1
-
35
-
-
78149459962
-
Genipin-induced inhibition of uncoupling protein-2 sensitizes drug-resistant cancer cells to cytotoxic agents
-
Mailloux, R. J., Adjeitey, C. N., and Harper, M. E. (2010) Genipin-induced inhibition of uncoupling protein-2 sensitizes drug-resistant cancer cells to cytotoxic agents. PLoS One 5, e13289.
-
(2010)
PLoS One
, vol.5
, pp. e13289
-
-
Mailloux, R.J.1
Adjeitey, C.N.2
Harper, M.E.3
-
36
-
-
0035676786
-
Antithrombotic effect of geniposide and genipin in the mouse thrombosis model
-
Suzuki, Y., Kondo, K., Ikeda, Y., and Umemura, K. (2001) Antithrombotic effect of geniposide and genipin in the mouse thrombosis model. Planta Med. 67, 807-810.
-
(2001)
Planta Med.
, vol.67
, pp. 807-810
-
-
Suzuki, Y.1
Kondo, K.2
Ikeda, Y.3
Umemura, K.4
-
37
-
-
67650751098
-
Neuroprotective action of genipin on tunicamycin-induced cytotoxicity in neuro2a cells
-
Tanaka, M., Yamazaki, M., and Chiba, K. (2009) Neuroprotective action of genipin on tunicamycin-induced cytotoxicity in neuro2a cells. Biol. Pharm. Bull. 32, 1220-1223.
-
(2009)
Biol. Pharm. Bull.
, vol.32
, pp. 1220-1223
-
-
Tanaka, M.1
Yamazaki, M.2
Chiba, K.3
-
38
-
-
77954376984
-
Effect of genipin on cholestasis induced by estradiol-17beta-glucuronide and lithocholate-3-O-glucuornide in rats
-
Goto, H., and Takikawa, H. (2010) Effect of genipin on cholestasis induced by estradiol-17beta-glucuronide and lithocholate-3-O-glucuornide in rats. Hepatol. Res. 40, 524-529.
-
(2010)
Hepatol. Res.
, vol.40
, pp. 524-529
-
-
Goto, H.1
Takikawa, H.2
-
39
-
-
78650945927
-
Potent inhibitor design against H1N1 swine influenza: Structure-based and molecular dynamics analysis for M2 inhibitors from traditional Chinese medicine database
-
Lin, C. H., Chang, T. T., Sun, M. F., Chen, H. Y., Tsai, F. J., Chang, K. L., Fisher, M., and Chen, C. Y. (2011) Potent inhibitor design against H1N1 swine influenza: Structure-based and molecular dynamics analysis for M2 inhibitors from traditional Chinese medicine database. J. Biomol. Struct. Dyn. 28, 471-482.
-
(2011)
J. Biomol. Struct. Dyn.
, vol.28
, pp. 471-482
-
-
Lin, C.H.1
Chang, T.T.2
Sun, M.F.3
Chen, H.Y.4
Tsai, F.J.5
Chang, K.L.6
Fisher, M.7
Chen, C.Y.8
-
40
-
-
3042788976
-
Antiinflammatory effects of genipin, an active principle of gardenia
-
Koo, H. J., Song, Y. S., Kim, H. J., Lee, Y. H., Hong, S. M., Kim, S. J., Kim, B. C., Jin, C., Lim, C. J., and Park, E. H. (2004) Antiinflammatory effects of genipin, an active principle of gardenia. Eur. J. Pharmacol. 495, 201-208.
-
(2004)
Eur. J. Pharmacol.
, vol.495
, pp. 201-208
-
-
Koo, H.J.1
Song, Y.S.2
Kim, H.J.3
Lee, Y.H.4
Hong, S.M.5
Kim, S.J.6
Kim, B.C.7
Jin, C.8
Lim, C.J.9
Park, E.H.10
-
41
-
-
79960647993
-
Genipin Selectively Inhibits TNF-alpha-activated VCAM-1 But Not ICAM-1 Expression by Upregulation of PPAR-gamma in Human Endothelial Cells
-
Hwa, J. S., Mun, L., Kim, H. J., Seo, H. G., Lee, J. H., Kwak, J. H., Lee, D. U., and Chang, K. C. (2011) Genipin Selectively Inhibits TNF-alpha-activated VCAM-1 But Not ICAM-1 Expression by Upregulation of PPAR-gamma in Human Endothelial Cells. Korean J. Physiol. Pharmacol. 15, 157-162.
-
(2011)
Korean J. Physiol. Pharmacol.
, vol.15
, pp. 157-162
-
-
Hwa, J.S.1
Mun, L.2
Kim, H.J.3
Seo, H.G.4
Lee, J.H.5
Kwak, J.H.6
Lee, D.U.7
Chang, K.C.8
-
42
-
-
77949485246
-
Genipin inhibits the inflammatory response of rat brain microglial cells
-
Nam, K. N., Choi, Y. S., Jung, H. J., Park, G. H., Park, J. M., Moon, S. K., Cho, K. H., Kang, C., Kang, I., Oh, M. S., and Lee, E. H. (2010) Genipin inhibits the inflammatory response of rat brain microglial cells. Int. Immunopharmacol. 10, 493-499.
-
(2010)
Int. Immunopharmacol.
, vol.10
, pp. 493-499
-
-
Nam, K.N.1
Choi, Y.S.2
Jung, H.J.3
Park, G.H.4
Park, J.M.5
Moon, S.K.6
Cho, K.H.7
Kang, C.8
Kang, I.9
Oh, M.S.10
Lee, E.H.11
-
43
-
-
44249090414
-
Anti-inflammatory effects of catechols in lipopolysaccharides-timulated microglia cells: Inhibition of microglial neurotoxicity
-
Zheng, L. T., Ryu, G. M., Kwon, B. M., Lee, W. H., and Suk, K. (2008) Anti-inflammatory effects of catechols in lipopolysaccharides-timulated microglia cells: inhibition of microglial neurotoxicity. Eur. J. Pharmacol. 588, 106-113.
-
(2008)
Eur. J. Pharmacol.
, vol.588
, pp. 106-113
-
-
Zheng, L.T.1
Ryu, G.M.2
Kwon, B.M.3
Lee, W.H.4
Suk, K.5
-
44
-
-
77950547609
-
Locus ceruleus controls Alzheimer ' s disease pathology by modulating microglial functions through norepinephrine
-
Heneka, M. T., Nadrigny, F., Regen, T., Martinez-Hernandez, A., Dumitrescu-Ozimek, L., Terwel, D., Jardanhazi-Kurutz, D., Walter, J., Kirchhoff, F., Hanisch, U. K., and Kummer, M. P. (2010) Locus ceruleus controls Alzheimer ' s disease pathology by modulating microglial functions through norepinephrine. Proc. Natl. Acad. Sci. U.S.A. 107, 6058-6063.
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 6058-6063
-
-
Heneka, M.T.1
Nadrigny, F.2
Regen, T.3
Martinez-Hernandez, A.4
Dumitrescu-Ozimek, L.5
Terwel, D.6
Jardanhazi-Kurutz, D.7
Walter, J.8
Kirchhoff, F.9
Hanisch, U.K.10
Kummer, M.P.11
-
45
-
-
84877771398
-
Targeting norepinephrine in mild cognitive impairment and Alzheimer's disease
-
Chalermpalanupap, T., Kinkead, B., Hu, W. T., Kummer, M. P., Hammerschmidt, T., Heneka, M. T., Weinshenker, D., and Levey, A. I. (2013) Targeting norepinephrine in mild cognitive impairment and Alzheimer's disease. Alzheimer's Res. Ther. 5, 21.
-
(2013)
Alzheimer's Res. Ther.
, vol.5
, pp. 21
-
-
Chalermpalanupap, T.1
Kinkead, B.2
Hu, W.T.3
Kummer, M.P.4
Hammerschmidt, T.5
Heneka, M.T.6
Weinshenker, D.7
Levey, A.I.8
-
46
-
-
22244485338
-
Peripheral injection of lipopolysaccharide enhances expression of inflammatory cytokines in murine locus coeruleus: Possible role of increased norepinephrine turnover
-
Kaneko, Y. S., Mori, K., Nakashima, A., Sawada, M., Nagatsu, I., and Ota, A. (2005) Peripheral injection of lipopolysaccharide enhances expression of inflammatory cytokines in murine locus coeruleus: Possible role of increased norepinephrine turnover. J. Neurochem. 94, 393-404.
-
(2005)
J. Neurochem.
, vol.94
, pp. 393-404
-
-
Kaneko, Y.S.1
Mori, K.2
Nakashima, A.3
Sawada, M.4
Nagatsu, I.5
Ota, A.6
-
47
-
-
0035873933
-
The anti-inflammatory interactions of epinephrine with human neutrophils in vitro are achieved by cyclic AMP-mediated accelerated resequestration of cytosolic calcium
-
Tintinger, G. R., Theron, A. J., Anderson, R., and Ker, J. A. (2001) The anti-inflammatory interactions of epinephrine with human neutrophils in vitro are achieved by cyclic AMP-mediated accelerated resequestration of cytosolic calcium. Biochem. Pharmacol. 61, 1319-1328.
-
(2001)
Biochem. Pharmacol.
, vol.61
, pp. 1319-1328
-
-
Tintinger, G.R.1
Theron, A.J.2
Anderson, R.3
Ker, J.A.4
-
48
-
-
67649565938
-
Influence of acute epinephrine infusion on endotoxin-induced parameters of heart rate variability: A randomized controlled trial
-
Jan, B. U., Coyle, S. M., Oikawa, L. O., Lu, S. E., Calvano, S. E., Lehrer, P. M., and Lowry, S. F. (2009) Influence of acute epinephrine infusion on endotoxin-induced parameters of heart rate variability: A randomized controlled trial. Ann. Surg. 249, 750-756.
-
(2009)
Ann. Surg.
, vol.249
, pp. 750-756
-
-
Jan, B.U.1
Coyle, S.M.2
Oikawa, L.O.3
Lu, S.E.4
Calvano, S.E.5
Lehrer, P.M.6
Lowry, S.F.7
-
49
-
-
80052264023
-
Experimental approaches to study functional recovery following cerebral ischemia
-
Lipsanen, A., and Jolkkonen, J. (2011) Experimental approaches to study functional recovery following cerebral ischemia. Cell. Mol. Life Sci. 68, 3007-3017.
-
(2011)
Cell. Mol. Life Sci.
, vol.68
, pp. 3007-3017
-
-
Lipsanen, A.1
Jolkkonen, J.2
-
50
-
-
34547678127
-
Antiinflammatory effects of a combined herbal preparation (RAH13) of Phellodendron amurense and Coptis chinensis in animal models of inflammation
-
Park, E. K., Rhee, H. I., Jung, H. S., Ju, S. M., Lee, Y. A., Lee, S. H., Hong, S. J., Yang, H. I., Yoo, M. C., and Kim, K. S. (2007) Antiinflammatory effects of a combined herbal preparation (RAH13) of Phellodendron amurense and Coptis chinensis in animal models of inflammation. Phytother. Res. 21, 746-750.
-
(2007)
Phytother. Res.
, vol.21
, pp. 746-750
-
-
Park, E.K.1
Rhee, H.I.2
Jung, H.S.3
Ju, S.M.4
Lee, Y.A.5
Lee, S.H.6
Hong, S.J.7
Yang, H.I.8
Yoo, M.C.9
Kim, K.S.10
-
51
-
-
39149085654
-
Caffeine activates the PI3K/Akt pathway and prevents apoptotic cell death in a Parkinson's disease model of SH-SY5Y cells
-
Nakaso, K., Ito, S., and Nakashima, K. (2008) Caffeine activates the PI3K/Akt pathway and prevents apoptotic cell death in a Parkinson's disease model of SH-SY5Y cells. Neurosci. Lett. 432, 146-150.
-
(2008)
Neurosci. Lett.
, vol.432
, pp. 146-150
-
-
Nakaso, K.1
Ito, S.2
Nakashima, K.3
-
52
-
-
84899938968
-
EPO-Dependent Activation of PI3K/Akt/FoxO3a Signalling Mediates Neuroprotection in In Vitro and In Vivo Models of Parkinson's Disease
-
Jia, Y., Mo, S. J., Feng, Q. Q., Zhan, M. L., Ouyang, L. S., Chen, J. C., Ma, Y. X., Wu, J. J., and Lei, W. L. (2014) EPO-Dependent Activation of PI3K/Akt/FoxO3a Signalling Mediates Neuroprotection in In Vitro and In Vivo Models of Parkinson's Disease. J. Mol. Neurosci. 53, 117-124.
-
(2014)
J. Mol. Neurosci.
, vol.53
, pp. 117-124
-
-
Jia, Y.1
Mo, S.J.2
Feng, Q.Q.3
Zhan, M.L.4
Ouyang, L.S.5
Chen, J.C.6
Ma, Y.X.7
Wu, J.J.8
Lei, W.L.9
-
53
-
-
2342558065
-
Akt activity in Alzheimer's disease and other neurodegenerative disorders
-
Rickle, A., Bogdanovic, N., Volkman, I., Winblad, B., Ravid, R., and Cowburn, R. F. (2004) Akt activity in Alzheimer's disease and other neurodegenerative disorders. NeuroReport 15, 955-959.
-
(2004)
NeuroReport
, vol.15
, pp. 955-959
-
-
Rickle, A.1
Bogdanovic, N.2
Volkman, I.3
Winblad, B.4
Ravid, R.5
Cowburn, R.F.6
-
54
-
-
2442716392
-
TGF-beta1 represses activation and resultant death of microglia via inhibition of phosphatidylinositol 3-kinase activity
-
Kim, W. K., Hwang, S. Y., Oh, E. S., Piao, H. Z., Kim, K. W., and Han, I. O. (2004) TGF-beta1 represses activation and resultant death of microglia via inhibition of phosphatidylinositol 3-kinase activity. J. Immunol. 172, 7015-7023.
-
(2004)
J. Immunol.
, vol.172
, pp. 7015-7023
-
-
Kim, W.K.1
Hwang, S.Y.2
Oh, E.S.3
Piao, H.Z.4
Kim, K.W.5
Han, I.O.6
-
55
-
-
2142640818
-
5-Aminoimidazole-4-carboxamide riboside suppresses lipopolysaccharide-induced TNF-alpha production through inhibition of phosphatidylinositol 3-kinase/Akt activation in RAW 264.7 murine macrophages
-
Jhun, B. S., Jin, Q., Oh, Y. T., Kim, S. S., Kong, Y., Cho, Y. H., Ha, J., Baik, H. H., and Kang, I. (2004) 5-Aminoimidazole-4-carboxamide riboside suppresses lipopolysaccharide-induced TNF-alpha production through inhibition of phosphatidylinositol 3-kinase/Akt activation in RAW 264.7 murine macrophages. Biochem. Biophys. Res. Commun. 318, 372-380.
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.318
, pp. 372-380
-
-
Jhun, B.S.1
Jin, Q.2
Oh, Y.T.3
Kim, S.S.4
Kong, Y.5
Cho, Y.H.6
Ha, J.7
Baik, H.H.8
Kang, I.9
-
56
-
-
32544439901
-
Activation of adenosine A3 receptor suppresses lipopolysaccharide-induced TNF-alpha production through inhibition of PI 3-kinase/Akt and NFkappaB activation in murine BV2 microglial cells
-
Lee, J. Y., Jhun, B. S., Oh, Y. T., Lee, J. H., Choe, W., Baik, H. H., Ha, J., Yoon, K. S., Kim, S. S., and Kang, I. (2006) Activation of adenosine A3 receptor suppresses lipopolysaccharide-induced TNF-alpha production through inhibition of PI 3-kinase/Akt and NFkappaB activation in murine BV2 microglial cells. Neurosci. Lett. 396, 1-6.
-
(2006)
Neurosci. Lett.
, vol.396
, pp. 1-6
-
-
Lee, J.Y.1
Jhun, B.S.2
Oh, Y.T.3
Lee, J.H.4
Choe, W.5
Baik, H.H.6
Ha, J.7
Yoon, K.S.8
Kim, S.S.9
Kang, I.10
-
57
-
-
41149177024
-
Pioglitazone inhibition of lipopolysaccharide-induced nitric oxide synthase is associated with altered activity of p38 MAP kinase and PI3K/Akt
-
Xing, B., Xin, T., Hunter, R. L., and Bing, G. (2008) Pioglitazone inhibition of lipopolysaccharide-induced nitric oxide synthase is associated with altered activity of p38 MAP kinase and PI3K/Akt. J. Neuroinflammation 5, 4.
-
(2008)
J. Neuroinflammation
, vol.5
, pp. 4
-
-
Xing, B.1
Xin, T.2
Hunter, R.L.3
Bing, G.4
-
58
-
-
33747347753
-
Cordycepin inhibits lipopolysaccharide-induced inflammation by the suppression of NF-kappaB through Akt and p38 inhibition in RAW 264.7 macrophage cells
-
Kim, H. G., Shrestha, B., Lim, S. Y., Yoon, D. H., Chang, W. C., Shin, D. J., Han, S. K., Park, S. M., Park, J. H., Park, H. I., Sung, J. M., Jang, Y., Chung, N., Hwang, K. C., and Kim, T. W. (2006) Cordycepin inhibits lipopolysaccharide-induced inflammation by the suppression of NF-kappaB through Akt and p38 inhibition in RAW 264.7 macrophage cells. Eur. J. Pharmacol. 545, 192-199.
-
(2006)
Eur. J. Pharmacol.
, vol.545
, pp. 192-199
-
-
Kim, H.G.1
Shrestha, B.2
Lim, S.Y.3
Yoon, D.H.4
Chang, W.C.5
Shin, D.J.6
Han, S.K.7
Park, S.M.8
Park, J.H.9
Park, H.I.10
Sung, J.M.11
Jang, Y.12
Chung, N.13
Hwang, K.C.14
Kim, T.W.15
-
59
-
-
33750023475
-
Acacetin suppressed LPS-induced up-expression of iNOS and COX-2 in murine macrophages and TPA-induced tumor promotion in mice
-
Pan, M. H., Lai, C. S., Wang, Y. J., and Ho, C. T. (2006) Acacetin suppressed LPS-induced up-expression of iNOS and COX-2 in murine macrophages and TPA-induced tumor promotion in mice. Biochem. Pharmacol. 72, 1293-1303.
-
(2006)
Biochem. Pharmacol.
, vol.72
, pp. 1293-1303
-
-
Pan, M.H.1
Lai, C.S.2
Wang, Y.J.3
Ho, C.T.4
-
60
-
-
77649160181
-
PI3K inhibition in inflammation: Toward tailored therapies for specific diseases
-
Ghigo, A., Damilano, F., Braccini, L., and Hirsch, E. (2010) PI3K inhibition in inflammation: Toward tailored therapies for specific diseases. BioEssays 32, 185-196.
-
(2010)
BioEssays
, vol.32
, pp. 185-196
-
-
Ghigo, A.1
Damilano, F.2
Braccini, L.3
Hirsch, E.4
-
61
-
-
71049149246
-
Identification of the bioactive constituent and its mechanisms of action in mediating the anti-inflammatory effects of black cohosh and related Cimicifuga species on human primary blood macrophages
-
Yang, C. L., Chik, S. C., Li, J. C., Cheung, B. K., and Lau, A. S. (2009) Identification of the bioactive constituent and its mechanisms of action in mediating the anti-inflammatory effects of black cohosh and related Cimicifuga species on human primary blood macrophages. J. Med. Chem. 52, 6707-6715.
-
(2009)
J. Med. Chem.
, vol.52
, pp. 6707-6715
-
-
Yang, C.L.1
Chik, S.C.2
Li, J.C.3
Cheung, B.K.4
Lau, A.S.5
-
62
-
-
79952447872
-
Isolation and identification of anti-inflammatory constituents from Ligusticum chuanxiong and their underlying mechanisms of action on microglia
-
Or, T. C., Yang, C. L., Law, A. H., Li, J. C., and Lau, A. S. (2011) Isolation and identification of anti-inflammatory constituents from Ligusticum chuanxiong and their underlying mechanisms of action on microglia. Neuropharmacology 60, 823-831.
-
(2011)
Neuropharmacology
, vol.60
, pp. 823-831
-
-
Or, T.C.1
Yang, C.L.2
Law, A.H.3
Li, J.C.4
Lau, A.S.5
-
63
-
-
79953116123
-
Differential effects of Radix Paeoniae Rubra (Chishao) on cytokine and chemokine expression inducible by mycobacteria
-
Wang, L., Yang, C. L., Or, T. C., Chen, G., Zhou, J., Li, J. C., and Lau, A. S. (2011) Differential effects of Radix Paeoniae Rubra (Chishao) on cytokine and chemokine expression inducible by mycobacteria. Chin. Med. 6, 14.
-
(2011)
Chin. Med.
, vol.6
, pp. 14
-
-
Wang, L.1
Yang, C.L.2
Or, T.C.3
Chen, G.4
Zhou, J.5
Li, J.C.6
Lau, A.S.7
-
64
-
-
0027080364
-
The MTT cell viability assay for cytotoxicity testing in multidrug-resistant human leukemic cells
-
Marks, D. C., Belov, L., Davey, M. W., Davey, R. A., and Kidman, A. D. (1992) The MTT cell viability assay for cytotoxicity testing in multidrug-resistant human leukemic cells. Leuk. Res. 16, 1165-1173.
-
(1992)
Leuk. Res.
, vol.16
, pp. 1165-1173
-
-
Marks, D.C.1
Belov, L.2
Davey, M.W.3
Davey, R.A.4
Kidman, A.D.5
-
65
-
-
0031033145
-
Nitric oxide scavenging by curcuminoids
-
Sreejayan, and Rao, M. N. (1997) Nitric oxide scavenging by curcuminoids. J. Pharm. Pharmacol. 49, 105-107.
-
(1997)
J. Pharm. Pharmacol.
, vol.49
, pp. 105-107
-
-
Sreejayan1
Rao, M.N.2
-
66
-
-
79952447872
-
Isolation and identification of anti-inflammatory constituents from Ligusticum chuanxiong and their underlying mechanisms of action on microglia
-
Or, T. C. T., Yang, C. L. H., Law, A. H. Y., Li, J. C. B., and Lau, A. S. Y. (2011) Isolation and identification of anti-inflammatory constituents from Ligusticum chuanxiong and their underlying mechanisms of action on microglia. Neuropharmacology 60, 823-831.
-
(2011)
Neuropharmacology
, vol.60
, pp. 823-831
-
-
Or, T.C.T.1
Yang, C.L.H.2
Law, A.H.Y.3
Li, J.C.B.4
Lau, A.S.Y.5
-
67
-
-
74549115190
-
A novel anti-mycobacterial function of mitogen-activated protein kinase phosphatase-1
-
Cheung, B. K. W., Yim, H. C. H., Lee, N. C. M., and Lau, A. S. Y. (2009) A novel anti-mycobacterial function of mitogen-activated protein kinase phosphatase-1. BMC Immunol. 10, 64.
-
(2009)
BMC Immunol.
, vol.10
, pp. 64
-
-
Cheung, B.K.W.1
Yim, H.C.H.2
Lee, N.C.M.3
Lau, A.S.Y.4
-
68
-
-
33748136861
-
Tissue-specific expression of TRP channel genes in the mouse and its variation in three different mouse strains
-
Kunert-Keil, C., Bisping, F., Kruger, J., and Brinkmeier, H. (2006) Tissue-specific expression of TRP channel genes in the mouse and its variation in three different mouse strains. BMC Genomics 7, 159.
-
(2006)
BMC Genomics
, vol.7
, pp. 159
-
-
Kunert-Keil, C.1
Bisping, F.2
Kruger, J.3
Brinkmeier, H.4
-
69
-
-
62449233690
-
Cardiac-targeted expression of soluble fas attenuates doxorubicin-induced cardiotoxicity in mice
-
Niu, J., Azfer, A., Wang, K., Wang, X., and Kolattukudy, P. E. (2009) Cardiac-targeted expression of soluble fas attenuates doxorubicin-induced cardiotoxicity in mice. J. Pharmacol. Exp. Ther. 328, 740-748.
-
(2009)
J. Pharmacol. Exp. Ther.
, vol.328
, pp. 740-748
-
-
Niu, J.1
Azfer, A.2
Wang, K.3
Wang, X.4
Kolattukudy, P.E.5
-
70
-
-
23244461479
-
p38 mitogen-activated protein kinase-dependent hyperinduction of tumor necrosis factor alpha expression in response to avian influenza virus H5N1
-
Lee, D. C. W., Cheung, C. Y., Law, A. H. Y., Mok, C. K. P., Peiris, M., and Lau, A. S. Y. (2005) p38 mitogen-activated protein kinase-dependent hyperinduction of tumor necrosis factor alpha expression in response to avian influenza virus H5N1. J. Virol. 79, 10147-10154.
-
(2005)
J. Virol.
, vol.79
, pp. 10147-10154
-
-
Lee, D.C.W.1
Cheung, C.Y.2
Law, A.H.Y.3
Mok, C.K.P.4
Peiris, M.5
Lau, A.S.Y.6
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