Antidiabetic and antihyperlipidemic activity of asiatic acid in diabetic rats, role of HMG CoA: In vivo and in silico approaches

Phytomedicine

Volumn 21, Issue 3, 2014, Pages 225-232

  Ramachandran, Vinayagam ^a   Saravanan, Ramalingam ^a   Senthilraja, Poomalai ^a  

^a ANNAMALAI UNIVERSITY   (India)

Author keywords

Antihyperlipidemic; Asiatic acid; Diabetes mellitus; HMG CoA reductase; Streptozotocin

Indexed keywords

3 HYDROXY 3 METHYLGLUTARYL COENZYME A; ASIATIC ACID; FATTY ACID; GLIBENCLAMIDE; HIGH DENSITY LIPOPROTEIN; INSULIN; LIPOPROTEIN LIPASE; LOW DENSITY LIPOPROTEIN; PHOSPHATIDYLCHOLINE STEROL ACYLTRANSFERASE; STREPTOZOCIN; TRIACYLGLYCEROL; 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A; ACYL COENZYME A; ANTIDIABETIC AGENT; ANTILIPEMIC AGENT; CHOLESTEROL; GLUCOSE BLOOD LEVEL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE (NADPH); PENTACYCLIC TRITERPENE; PLANT EXTRACT;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL SYNTHESIS; DRUG ACTIVITY; FATTY ACID BLOOD LEVEL; GLUCOSE BLOOD LEVEL; IN VIVO STUDY; LIGAND BINDING; LIPOPROTEIN BLOOD LEVEL; MALE; MOLECULAR DOCKING; NONHUMAN; PHOSPHOLIPID BLOOD LEVEL; PRIORITY JOURNAL; RAT; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; TRIACYLGLYCEROL BLOOD LEVEL; WISTAR RAT; ANIMAL; BIOSYNTHESIS; BLOOD; CENTELLA; CHEMISTRY; COMPLICATION; DIABETES MELLITUS, EXPERIMENTAL; DRUG EFFECTS; HYPERLIPIDEMIAS; LIPID METABOLISM; METABOLISM; PHYTOTHERAPY;

RATTUS; RATTUS NORVEGICUS;

ACYL COENZYME A; ANIMALS; BLOOD GLUCOSE; CENTELLA; CHOLESTEROL; DIABETES MELLITUS, EXPERIMENTAL; GLYBURIDE; HYDROXYMETHYLGLUTARYL-COA-REDUCTASES, NADP-DEPENDENT; HYPERLIPIDEMIAS; HYPOGLYCEMIC AGENTS; HYPOLIPIDEMIC AGENTS; LIPID METABOLISM; MALE; PENTACYCLIC TRITERPENES; PHYTOTHERAPY; PLANT EXTRACTS; RATS; RATS, WISTAR; TRIGLYCERIDES;

EID: 84896491626     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2013.08.027     Document Type: Article

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