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Volumn 85, Issue , 2014, Pages 51-57

Involvement of P38MAPK activation by NMDA receptors and non-NMDA receptors in amyloid-β peptide-induced neuronal loss in rat hippocampal CA1 and CA3 subfields

Author keywords

Alzheimer's disease; Amyloid peptide; NMDA receptors; Non NMDA receptors; P38MAPKs

Indexed keywords

4 [4 (4 FLUOROPHENYL) 5 (2 METHOXY 4 PYRIMIDINYL) 1 IMIDAZOLYL]CYCLOHEXANOL; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; AMANTADINE; AMYLOID BETA PROTEIN[1-42]; AMYLOID BETA PROTEIN[25-35]; CASPASE 3; IONOTROPIC RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE P38; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (25-35); PEPTIDE FRAGMENT;

EID: 84908508176     PISSN: 01680102     EISSN: 18728111     Source Type: Journal    
DOI: 10.1016/j.neures.2014.05.011     Document Type: Article
Times cited : (18)

References (34)
  • 1
    • 0026939298 scopus 로고
    • Role of excitotoxicity in human neurological disease
    • Beal M.F. Role of excitotoxicity in human neurological disease. Curr. Opin. Neurobiol. 1992, 2:657-662.
    • (1992) Curr. Opin. Neurobiol. , vol.2 , pp. 657-662
    • Beal, M.F.1
  • 2
    • 33747632142 scopus 로고    scopus 로고
    • MAPK-activated protein kinase 2 deficiency in microglia inhibits pro-inflammatory mediator release and resultant neurotoxicity. Relevance to neuroinflammation in a transgenic mouse model of Alzheimer disease
    • Culbert A.A., Skaper S.D., Howlett D.R., Evans N.A., Facci L., Soden P.E., Seymour Z.M., Guillot F., Gaestel M., Richardson J.C. MAPK-activated protein kinase 2 deficiency in microglia inhibits pro-inflammatory mediator release and resultant neurotoxicity. Relevance to neuroinflammation in a transgenic mouse model of Alzheimer disease. J. Biol. Chem. 2006, 281:23658-23667.
    • (2006) J. Biol. Chem. , vol.281 , pp. 23658-23667
    • Culbert, A.A.1    Skaper, S.D.2    Howlett, D.R.3    Evans, N.A.4    Facci, L.5    Soden, P.E.6    Seymour, Z.M.7    Guillot, F.8    Gaestel, M.9    Richardson, J.C.10
  • 3
    • 79551524309 scopus 로고    scopus 로고
    • Microarray analysis on human neuroblastoma cells exposed to aluminum, β(1-42)-amyloid or the β(1-42)-amyloid aluminum complex
    • Gatta V., Drago D., Fincati K., Valenti M.T., Dalle Carbonare L., Sensi S.L., Zatta P. Microarray analysis on human neuroblastoma cells exposed to aluminum, β(1-42)-amyloid or the β(1-42)-amyloid aluminum complex. PLoS ONE 2011, 6:e15965.
    • (2011) PLoS ONE , vol.6 , pp. e15965
    • Gatta, V.1    Drago, D.2    Fincati, K.3    Valenti, M.T.4    Dalle Carbonare, L.5    Sensi, S.L.6    Zatta, P.7
  • 4
  • 5
    • 0042838303 scopus 로고    scopus 로고
    • Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss
    • Gong Y., Chang L., Viola K.L., Lacor P.N., Lambert M.P., Finch C.E., Krafft G.A., Klein W.L. Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss. Proc. Natl. Acad. Sci. U.S.A. 2003, 100:10417-10422.
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 10417-10422
    • Gong, Y.1    Chang, L.2    Viola, K.L.3    Lacor, P.N.4    Lambert, M.P.5    Finch, C.E.6    Krafft, G.A.7    Klein, W.L.8
  • 6
    • 0035951486 scopus 로고    scopus 로고
    • Neuroscience. Glia tell neurons to build synapses
    • Helmuth L. Neuroscience. Glia tell neurons to build synapses. Science 2001, 291:569-570.
    • (2001) Science , vol.291 , pp. 569-570
    • Helmuth, L.1
  • 8
    • 33845411954 scopus 로고    scopus 로고
    • AMPAR removal underlies Abeta-induced synaptic depression and dendritic spine loss
    • Hsieh H., Boehm J., Sato C., Iwatsubo T., Tomita T., Sisodia S., Malinow R. AMPAR removal underlies Abeta-induced synaptic depression and dendritic spine loss. Neuron 2006, 52:831-843.
    • (2006) Neuron , vol.52 , pp. 831-843
    • Hsieh, H.1    Boehm, J.2    Sato, C.3    Iwatsubo, T.4    Tomita, T.5    Sisodia, S.6    Malinow, R.7
  • 9
    • 3042693940 scopus 로고    scopus 로고
    • Glutamate-mediated excitotoxicity and neurodegeneration in Alzheimer's disease
    • Hynd M.R., Scott H.L., Dodd P.R. Glutamate-mediated excitotoxicity and neurodegeneration in Alzheimer's disease. Neurochem. Int. 2004, 45:583-595.
    • (2004) Neurochem. Int. , vol.45 , pp. 583-595
    • Hynd, M.R.1    Scott, H.L.2    Dodd, P.R.3
  • 10
    • 0032891616 scopus 로고    scopus 로고
    • A central role for astrocytes in the inflammatory response to beta-amyloid; chemokines, cytokines and reactive oxygen species are produced
    • Johnstone M., Gearing A.J., Miller K.M. A central role for astrocytes in the inflammatory response to beta-amyloid; chemokines, cytokines and reactive oxygen species are produced. J. Neuroimmunol. 1999, 93:182-193.
    • (1999) J. Neuroimmunol. , vol.93 , pp. 182-193
    • Johnstone, M.1    Gearing, A.J.2    Miller, K.M.3
  • 11
    • 36448936747 scopus 로고    scopus 로고
    • Kinase activities increase during the development of tauopathy in htau mice
    • Kelleher I., Garwood C., Hanger D.P., Anderton B.H., Noble W. Kinase activities increase during the development of tauopathy in htau mice. J. Neurochem. 2007, 103:2256-2267.
    • (2007) J. Neurochem. , vol.103 , pp. 2256-2267
    • Kelleher, I.1    Garwood, C.2    Hanger, D.P.3    Anderton, B.H.4    Noble, W.5
  • 12
    • 33748792254 scopus 로고    scopus 로고
    • Beta-Amyloid-induced dynamin 1 degradation is mediated by N-methyl-d-aspartate receptors in hippocampal neurons
    • Kelly B.L., Ferreira A. beta-Amyloid-induced dynamin 1 degradation is mediated by N-methyl-d-aspartate receptors in hippocampal neurons. J. Biol. Chem. 2006, 281:28079-28089.
    • (2006) J. Biol. Chem. , vol.281 , pp. 28079-28089
    • Kelly, B.L.1    Ferreira, A.2
  • 13
    • 76749088358 scopus 로고    scopus 로고
    • Pathological roles of MAPK signaling pathways in human diseases
    • Kim E.K., Choi E.J. Pathological roles of MAPK signaling pathways in human diseases. Biochim. Biophys. Acta 2010, 1802:396-405.
    • (2010) Biochim. Biophys. Acta , vol.1802 , pp. 396-405
    • Kim, E.K.1    Choi, E.J.2
  • 14
    • 84888193014 scopus 로고    scopus 로고
    • Donepezil inhibits the amyloid-beta oligomer-induced microglial activation in vitro and in vivo
    • Kim H.G., Moon M., Choi J.G., Park G., Kim A.J., Hur J., Lee K.T., Oh M.S. Donepezil inhibits the amyloid-beta oligomer-induced microglial activation in vitro and in vivo. Neurotoxicology 2014, 40:23-32.
    • (2014) Neurotoxicology , vol.40 , pp. 23-32
    • Kim, H.G.1    Moon, M.2    Choi, J.G.3    Park, G.4    Kim, A.J.5    Hur, J.6    Lee, K.T.7    Oh, M.S.8
  • 15
    • 67249087641 scopus 로고    scopus 로고
    • Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake
    • Li S., Hong S., Shepardson N.E., Walsh D.M., Shankar G.M., Selkoe D. Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake. Neuron 2009, 62:788-801.
    • (2009) Neuron , vol.62 , pp. 788-801
    • Li, S.1    Hong, S.2    Shepardson, N.E.3    Walsh, D.M.4    Shankar, G.M.5    Selkoe, D.6
  • 18
    • 84865865850 scopus 로고    scopus 로고
    • Memantine prevents cognitive impairment and reduces Bcl-2 and caspase 8 immunoreactivity in rats injected with amyloid β(1-40)
    • Miguel-Hidalgo J.J., Paul I.A., Wanzo V., Banerjee P.K. Memantine prevents cognitive impairment and reduces Bcl-2 and caspase 8 immunoreactivity in rats injected with amyloid β(1-40). Eur. J. Pharmacol. 2012, 692:38-45.
    • (2012) Eur. J. Pharmacol. , vol.692 , pp. 38-45
    • Miguel-Hidalgo, J.J.1    Paul, I.A.2    Wanzo, V.3    Banerjee, P.K.4
  • 19
    • 84886641553 scopus 로고    scopus 로고
    • Dysfunctional synapse in Alzheimer's disease - a focus on NMDA receptors
    • Mota S.I., Ferreira I.L., Rego A.C. Dysfunctional synapse in Alzheimer's disease - a focus on NMDA receptors. Neuropharmacology 2014, 76:16-26.
    • (2014) Neuropharmacology , vol.76 , pp. 16-26
    • Mota, S.I.1    Ferreira, I.L.2    Rego, A.C.3
  • 20
    • 0028981219 scopus 로고
    • Structure-activity analyses of beta-amyloid peptides: contributions of the beta 25-35 region to aggregation and neurotoxicity
    • Pike C.J., Walencewicz-Wasserman A.J., Kosmoski J., Cribbs D.H., Glabe C.G., Cotman C.W. Structure-activity analyses of beta-amyloid peptides: contributions of the beta 25-35 region to aggregation and neurotoxicity. J. Neurochem. 1995, 64:253-265.
    • (1995) J. Neurochem. , vol.64 , pp. 253-265
    • Pike, C.J.1    Walencewicz-Wasserman, A.J.2    Kosmoski, J.3    Cribbs, D.H.4    Glabe, C.G.5    Cotman, C.W.6
  • 22
    • 0036580703 scopus 로고    scopus 로고
    • Activation of c-Jun N-terminal kinase and p38 in an Alzheimer's disease model is associated with amyloid deposition
    • Savage M.J., Lin Y.G., Ciallella J.R., Flood D.G., Scott R.W. Activation of c-Jun N-terminal kinase and p38 in an Alzheimer's disease model is associated with amyloid deposition. J. Neurosci. 2002, 22:3376-3385.
    • (2002) J. Neurosci. , vol.22 , pp. 3376-3385
    • Savage, M.J.1    Lin, Y.G.2    Ciallella, J.R.3    Flood, D.G.4    Scott, R.W.5
  • 23
    • 5644239087 scopus 로고    scopus 로고
    • Alzheimer disease: mechanistic understanding predicts novel therapies
    • Selkoe D.J. Alzheimer disease: mechanistic understanding predicts novel therapies. Ann. Intern. Med. 2004, 140:627-638.
    • (2004) Ann. Intern. Med. , vol.140 , pp. 627-638
    • Selkoe, D.J.1
  • 24
    • 77952875785 scopus 로고    scopus 로고
    • 2+ dyshomeostasis that is blocked by EGb761
    • 2+ dyshomeostasis that is blocked by EGb761. Neurochem. Int. 2010, 56:893-905.
    • (2010) Neurochem. Int. , vol.56 , pp. 893-905
    • Shi, C.1    Wu, F.2    Xu, J.3
  • 27
    • 11144247377 scopus 로고    scopus 로고
    • Interaction between a rat model of cerebral ischemia and beta-amyloid toxicity: inflammatory responses
    • Whitehead S.N., Hachinski V.C., Cechetto D.F. Interaction between a rat model of cerebral ischemia and beta-amyloid toxicity: inflammatory responses. Stroke 2005, 36:107-112.
    • (2005) Stroke , vol.36 , pp. 107-112
    • Whitehead, S.N.1    Hachinski, V.C.2    Cechetto, D.F.3
  • 28
    • 77953611524 scopus 로고    scopus 로고
    • Oligomerized Abeta25-35 induces increased tyrosine phosphorylation of NMDA receptor subunit 2A in rat hippocampal CA1 subfield
    • Wu G.M., Hou X.Y. Oligomerized Abeta25-35 induces increased tyrosine phosphorylation of NMDA receptor subunit 2A in rat hippocampal CA1 subfield. Brain Res. 2010, 1343:186-193.
    • (2010) Brain Res. , vol.1343 , pp. 186-193
    • Wu, G.M.1    Hou, X.Y.2
  • 29
    • 63849264211 scopus 로고    scopus 로고
    • Different protection of K252a and N-acetyl-l-cysteine against amyloid-beta peptide-induced cortical neuron apoptosis involving inhibition of MLK3-MKK7-JNK3 signal cascades
    • Xu Y., Hou X.Y., Liu Y., Zong Y.Y. Different protection of K252a and N-acetyl-l-cysteine against amyloid-beta peptide-induced cortical neuron apoptosis involving inhibition of MLK3-MKK7-JNK3 signal cascades. J. Neurosci. Res. 2009, 87:918-927.
    • (2009) J. Neurosci. Res. , vol.87 , pp. 918-927
    • Xu, Y.1    Hou, X.Y.2    Liu, Y.3    Zong, Y.Y.4
  • 30
    • 29844453962 scopus 로고    scopus 로고
    • The role of intracellular sodium in the regulation of NMDA-receptor-mediated channel activity and toxicity
    • Yu X.M. The role of intracellular sodium in the regulation of NMDA-receptor-mediated channel activity and toxicity. Mol. Neurobiol. 2006, 33:63-80.
    • (2006) Mol. Neurobiol. , vol.33 , pp. 63-80
    • Yu, X.M.1
  • 31
    • 77249122078 scopus 로고    scopus 로고
    • Glutamine synthetase down-regulation reduces astrocyte protection against glutamate excitotoxicity to neurons
    • Zou J., Wang Y.X., Dou F.F., Lü H.Z., Ma Z.W., Lu P.H., Xu X.M. Glutamine synthetase down-regulation reduces astrocyte protection against glutamate excitotoxicity to neurons. Neurochem. Int. 2010, 56:577-584.
    • (2010) Neurochem. Int. , vol.56 , pp. 577-584
    • Zou, J.1    Wang, Y.X.2    Dou, F.F.3    Lü, H.Z.4    Ma, Z.W.5    Lu, P.H.6    Xu, X.M.7
  • 32
    • 84897570705 scopus 로고    scopus 로고
    • MLK3-MKK3/6-P38MAPK cascades following NMDA receptor activation contributes to amyloid-β peptide-induced apoptosis in SH-SY5Y cells
    • Zhou F., Xu Y., Hou X.Y. MLK3-MKK3/6-P38MAPK cascades following NMDA receptor activation contributes to amyloid-β peptide-induced apoptosis in SH-SY5Y cells. J. Neurosci. Res. 2014, 92:808-817.
    • (2014) J. Neurosci. Res. , vol.92 , pp. 808-817
    • Zhou, F.1    Xu, Y.2    Hou, X.Y.3
  • 33
    • 84870294963 scopus 로고    scopus 로고
    • Aβ oligomers-induced toxicity is attenuated in cells cultured with NbActiv4™ medium
    • Zhou Y., Klein W.L. Aβ oligomers-induced toxicity is attenuated in cells cultured with NbActiv4™ medium. Neurotox. Res. 2012, 22:335-344.
    • (2012) Neurotox. Res. , vol.22 , pp. 335-344
    • Zhou, Y.1    Klein, W.L.2
  • 34
    • 0036770144 scopus 로고    scopus 로고
    • The role of mitogen-activated protein kinase pathways in Alzheimer's disease
    • Zhu X., Lee H.G., Raina A.K., Perry G., Smith M.A. The role of mitogen-activated protein kinase pathways in Alzheimer's disease. Neurosignals 2002, 11:270-281.
    • (2002) Neurosignals , vol.11 , pp. 270-281
    • Zhu, X.1    Lee, H.G.2    Raina, A.K.3    Perry, G.4    Smith, M.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.