PTEN antagonises Tcl1/hnRNPK-mediated G6PD pre-mRNA splicing which contributes to hepatocarcinogenesis

Gut

Volumn 63, Issue 10, 2014, Pages 1635-1647

  Hong, Xuehui ^a   Song, Ruipeng ^a   Song, Huiwen ^b   Zheng, Tongsen ^a   Wang, Jiabei ^a   Liang, Yingjian ^a   Qi, Shuyi ^a   Lu, Zhaoyang ^a   Song, Xuan ^a   Jiang, Hongchi ^a   Liu, Lianxin ^a   Zhang, Zhiyong ^c  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

^c ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; LACTIC ACID; LIPID; MEMBRANE PROTEIN; MESSENGER RNA; MESSENGER RNA PRECURSOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SORAFENIB; T CELL LEUKEMIA 1 PROTEIN; UNCLASSIFIED DRUG; GLYCOGEN SYNTHASE; HNRNPK PROTEIN, HUMAN; ONCOPROTEIN; PTEN PROTEIN, HUMAN; RIBONUCLEOPROTEIN; RNA PRECURSOR; TCL1A PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BIOCHEMISTRY; CANCER PROGNOSIS; CANCER TISSUE; CELL AGING; CELL PROLIFERATION; CONTROLLED STUDY; DRUG SENSITIVITY; ENZYME PHOSPHORYLATION; GENE EXPRESSION; GENE SILENCING; GLUCONEOGENESIS; GLUCOSE INTAKE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; LIPID STORAGE; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; LIVER PARENCHYMA; LIVER SURGERY; MAJOR CLINICAL STUDY; MALE; MASS SPECTROMETRY; METABOLIC REGULATION; MOLECULAR BIOLOGY; MOUSE; NONHUMAN; OVERALL SURVIVAL; PENTOSE PHOSPHATE CYCLE; POSTOPERATIVE CARE; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; RNA SPLICING; SIGNAL TRANSDUCTION; ANIMAL; BAGG ALBINO MOUSE; EXPERIMENTAL LIVER NEOPLASM; GENETICS; GLUCOSE METABOLISM; KNOCKOUT MOUSE; LIVER METABOLISM; METABOLISM; MOLECULAR MECHANISMS; PHOSPHORYLATION; PHYSIOLOGY;

GLUCOSE METABOLISM; HEPATOCELLULAR CARCINOMA; LIVER METABOLISM; MOLECULAR BIOLOGY; MOLECULAR MECHANISMS;

ANIMALS; CARCINOMA, HEPATOCELLULAR; GLUCOSE; GLUCOSEPHOSPHATE DEHYDROGENASE; GLYCOGEN SYNTHASE; HUMANS; LIVER NEOPLASMS, EXPERIMENTAL; MALE; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; PENTOSE PHOSPHATE PATHWAY; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS; PTEN PHOSPHOHYDROLASE; RIBONUCLEOPROTEINS; RNA PRECURSORS; RNA SPLICING;

EID: 84908500698     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gutjnl-2013-305302     Document Type: Article

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