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Volumn 5, Issue 4, 2014, Pages 179-184

In vitro evaluation of anticancer potentials of lupeol isolated from Elephantopus scaber L. on MCF-7 cell line

Author keywords

Anti apoptotic protein; apoptosis; cell death; lupeol

Indexed keywords

LACTATE DEHYDROGENASE; LUPEOL; PROTEIN BCL 2; PROTEIN BCL XL;

EID: 84908463348     PISSN: 22314040     EISSN: 09762094     Source Type: Journal    
DOI: 10.4103/2231-4040.143037     Document Type: Article
Times cited : (63)

References (31)
  • 4
    • 0031028432 scopus 로고    scopus 로고
    • Natural products in drug discovery and development
    • Cragg GM, Newman DJ, Snader KM. Natural products in drug discovery and development. J Nat Prod 1997;60:52-60.
    • (1997) J Nat Prod , vol.60 , pp. 52-60
    • Cragg, G.M.1    Newman, D.J.2    Snader, K.M.3
  • 5
    • 0034656866 scopus 로고    scopus 로고
    • A comparison of complementary therapy use between breast cancer patients and patients with other primary tumor sites
    • Morris KT, Johnson N, Homer L, Walts D. A comparison of complementary therapy use between breast cancer patients and patients with other primary tumor sites. Am J Surg 2000;179:407-11.
    • (2000) Am J Surg , vol.179 , pp. 407-411
    • Morris, K.T.1    Johnson, N.2    Homer, L.3    Walts, D.4
  • 6
    • 0031884963 scopus 로고    scopus 로고
    • Dietary supplement use by women at risk for breast cancer recurrence. The Women's Healthy Eating and Living Study Group
    • Newman V, Rock CL, Faerber S, Flatt SW, Wright FA, Pierce JP. Dietary supplement use by women at risk for breast cancer recurrence. The Women's Healthy Eating and Living Study Group. J Am Diet Assoc 1998;98:285-92.
    • (1998) J Am Diet Assoc , vol.98 , pp. 285-292
    • Newman, V.1    Rock, C.L.2    Faerber, S.3    Flatt, S.W.4    Wright, F.A.5    Pierce, J.P.6
  • 7
    • 4444279847 scopus 로고    scopus 로고
    • Global promotion of herbal medicine: Lndia's opportunity
    • Dubey NK, Kumar R, Tripathi P. Global promotion of herbal medicine: lndia's opportunity. Curr Sci 2004;86:37-41.
    • (2004) Curr Sci , vol.86 , pp. 37-41
    • Dubey, N.K.1    Kumar, R.2    Tripathi, P.3
  • 10
    • 82055169258 scopus 로고    scopus 로고
    • Elephantopus scaber induces cytotoxicity in MCF-7 human breast cancer cells via p53-induced apoptosis
    • Wan YH, Swee KY, Chai LH, Abdul RR, Abdul AS, Noorjahan BA. Elephantopus scaber induces cytotoxicity in MCF-7 human breast cancer cells via p53-induced apoptosis. J Med Plants Res 2011;5:5741-9.
    • (2011) J Med Plants Res , vol.5 , pp. 5741-5749
    • Wan, Y.H.1    Swee, K.Y.2    Chai, L.H.3    Abdul, R.R.4    Abdul, A.S.5    Noorjahan, B.A.6
  • 12
    • 84862845344 scopus 로고    scopus 로고
    • Anti-inflammatory and antioxidant activities of constituents isolated from Pueraria lobata roots
    • Jin SE, Son YK, Min BS, Jung HA, Choi JS. Anti-inflammatory and antioxidant activities of constituents isolated from Pueraria lobata roots. Arch Pharm Res 2012;35:823-37.
    • (2012) Arch Pharm Res , vol.35 , pp. 823-837
    • Jin, S.E.1    Son, Y.K.2    Min, B.S.3    Jung, H.A.4    Choi, J.S.5
  • 13
    • 20444466931 scopus 로고    scopus 로고
    • Expression of estrogen receptor alpha gene in breast cancer cells treated with transcription factor decoy is modulated by Bangladeshi natural plant extracts
    • Lambertini E, Lampronti I, Penolazzi L, Khan MT, Ather A, Giorgi G, et al. Expression of estrogen receptor alpha gene in breast cancer cells treated with transcription factor decoy is modulated by Bangladeshi natural plant extracts. Oncol Res 2005;15:69-79.
    • (2005) Oncol Res , vol.15 , pp. 69-79
    • Lambertini, E.1    Lampronti, I.2    Penolazzi, L.3    Khan, M.T.4    Ather, A.5    Giorgi, G.6
  • 14
    • 80051691651 scopus 로고    scopus 로고
    • Lupeol, a novel androgen receptor inhibitor: Implications in prostate cancer therapy
    • Siddique HR, Mishra SK, Karnes RJ, Saleem M. Lupeol, a novel androgen receptor inhibitor: implications in prostate cancer therapy. Clin Cancer Res 2011;17:5379-91.
    • (2011) Clin Cancer Res , vol.17 , pp. 5379-5391
    • Siddique, H.R.1    Mishra, S.K.2    Karnes, R.J.3    Saleem, M.4
  • 15
    • 84886769058 scopus 로고    scopus 로고
    • The dietary terpene lupeol targets colorectal cancer cells with constitutively active Wnt/â-catenin signaling
    • Tarapore RS, Siddiqui IA, Adhami VM, Spiegelman VS, Mukhtar H. The dietary terpene lupeol targets colorectal cancer cells with constitutively active Wnt/â-catenin signaling. Mol Nutr Food Res 2013;57:1950-8.
    • (2013) Mol Nutr Food Res , vol.57 , pp. 1950-1958
    • Tarapore, R.S.1    Siddiqui, I.A.2    Adhami, V.M.3    Spiegelman, V.S.4    Mukhtar, H.5
  • 16
    • 3142676732 scopus 로고    scopus 로고
    • Lupeol modulates NF-kappaB and PI3K/Akt pathways and inhibits skin cancer in CD-1 mice
    • Saleem M, Afaq F, Adhami VM, Mukhtar H. Lupeol modulates NF-kappaB and PI3K/Akt pathways and inhibits skin cancer in CD-1 mice. Oncogene 2004;23:5203-14.
    • (2004) Oncogene , vol.23 , pp. 5203-5214
    • Saleem, M.1    Afaq, F.2    Adhami, V.M.3    Mukhtar, H.4
  • 17
    • 84886735294 scopus 로고    scopus 로고
    • PI3-kinase inhibition synergistically promoted the anti-tumor effect of lupeol in hepatocellular carcinoma
    • Liu F, He Y, Liang Y, Wen L, Zhu Y, Wu Y, et al. PI3-kinase inhibition synergistically promoted the anti-tumor effect of lupeol in hepatocellular carcinoma. Cancer Cell Int 2013;13:108.
    • (2013) Cancer Cell Int , vol.13 , pp. 108
    • Liu, F.1    He, Y.2    Liang, Y.3    Wen, L.4    Zhu, Y.5    Wu, Y.6
  • 18
    • 78751552761 scopus 로고    scopus 로고
    • Lupeol targets liver tumor-initiating cells through phosphatase and tensin homolog modulation
    • Lee TK, Castilho A, Cheung VC, Tang KH, Ma S, Ng IO. Lupeol targets liver tumor-initiating cells through phosphatase and tensin homolog modulation. Hepatology 2011;53:160-70.
    • (2011) Hepatology , vol.53 , pp. 160-170
    • Lee, T.K.1    Castilho, A.2    Cheung, V.C.3    Tang, K.H.4    Ma, S.5    Ng, I.O.6
  • 19
    • 84878009432 scopus 로고    scopus 로고
    • The enhanced effect of lupeol on the destruction of gastric cancer cells by NK cells
    • Wu XT, Liu JQ, Lu XT, Chen FX, Zhou ZH, Wang T, et al. The enhanced effect of lupeol on the destruction of gastric cancer cells by NK cells. Int Immunopharmacol 2013;16:332-40.
    • (2013) Int Immunopharmacol , vol.16 , pp. 332-340
    • Wu, X.T.1    Liu, J.Q.2    Lu, X.T.3    Chen, F.X.4    Zh, Z.5    Wang, T.6
  • 21
    • 0642368436 scopus 로고    scopus 로고
    • Plant-derived triterpenoids as potential antineoplastic agents
    • Setzer WN, Setzer MC. Plant-derived triterpenoids as potential antineoplastic agents. Mini Rev Med Chem 2003;3:540-56.
    • (2003) Mini Rev Med Chem , vol.3 , pp. 540-556
    • Setzer, W.N.1    Setzer, M.C.2
  • 22
    • 34247526984 scopus 로고    scopus 로고
    • Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer
    • Liby KT, Yore MM, Sporn MB. Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer. Nat Rev Cancer 2007;7:357-69.
    • (2007) Nat Rev Cancer , vol.7 , pp. 357-369
    • Liby, K.T.1    Yore, M.M.2    Sporn, M.B.3
  • 23
    • 74049157757 scopus 로고    scopus 로고
    • Pentacyclic triterpenes of the lupane, oleanane and ursane group as tools in cancer therapy
    • Laszczyk MN. Pentacyclic triterpenes of the lupane, oleanane and ursane group as tools in cancer therapy. Planta Med 2009;75:1549-60.
    • (2009) Planta Med , vol.75 , pp. 1549-1560
    • Laszczyk, M.N.1
  • 24
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr JF, Wyllie AH, Currie AR. Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 1972;26:239-57.
    • (1972) Br J Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.1    Wyllie, A.H.2    Currie, A.R.3
  • 25
    • 0026504147 scopus 로고
    • Social controls on cell survival and cell death
    • Raff MC. Social controls on cell survival and cell death. Nature 1992;356:397-400.
    • (1992) Nature , vol.356 , pp. 397-400
    • Raff, M.C.1
  • 26
    • 0031037897 scopus 로고    scopus 로고
    • The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
    • Kluck RM, Bossy-Wetzel E, Green DR, Newmeyer DD. The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis. Science 1997;275:1132-6.
    • (1997) Science , vol.275 , pp. 1132-1136
    • Kluck, R.M.1    Bossy-Wetzel, E.2    Green, D.R.3    Newmeyer, D.D.4
  • 27
    • 0030785790 scopus 로고    scopus 로고
    • The central executioner of apoptosis: Multiple connections between protease activation and mitochondria in Fas/APO-1/CD95-and ceramide-induced apoptosis
    • Susin SA, Zamzami N, Castedo M, Daugas E, Wang HG, Geley S, et al. The central executioner of apoptosis: Multiple connections between protease activation and mitochondria in Fas/APO-1/CD95-and ceramide-induced apoptosis. J Exp Med 1997;186:25-37.
    • (1997) J Exp Med , vol.186 , pp. 25-37
    • Susin, S.A.1    Zamzami, N.2    Castedo, M.3    Daugas, E.4    Wang, H.G.5    Geley, S.6
  • 28
    • 0031036872 scopus 로고    scopus 로고
    • Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked
    • Yang J, Liu X, Bhalla K, Kim CN, Ibrado AM, Cai J, et al. Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked. Science 1997;275:1129-32.
    • (1997) Science , vol.275 , pp. 1129-1132
    • Yang, J.1    Liu, X.2    Bhalla, K.3    Kim, C.N.4    Ibrado, A.M.5    Cai, J.6
  • 29
    • 0033519705 scopus 로고    scopus 로고
    • Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC
    • Shimizu S, Narita M, Tsujimoto Y. Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC. Nature 1999;399:483-7.
    • (1999) Nature , vol.399 , pp. 483-487
    • Shimizu, S.1    Narita, M.2    Tsujimoto, Y.3
  • 31
    • 0842304280 scopus 로고    scopus 로고
    • Induction of apoptosis and down-regulation of Bcl-XL in cancer cells by a novel small molecule 2[[3-(2,3-dichlorophenoxy) propyl] amino] ethanol
    • Wu S, Zhu H, Gu J, Zhang L, Teraishi F, Davis JJ, et al. Induction of apoptosis and down-regulation of Bcl-XL in cancer cells by a novel small molecule, 2[[3-(2,3-dichlorophenoxy) propyl] amino] ethanol. Cancer Res 2004;64:1110-3.
    • (2004) Cancer Res , vol.64 , pp. 1110-1113
    • Wu, S.1    Zhu, H.2    Gu, J.3    Zhang, L.4    Teraishi, F.5    Davis, J.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.