Detection of lipid-linked peptidoglycan precursors by exploiting an unexpected transpeptidase reaction

Journal of the American Chemical Society

Volumn 136, Issue 42, 2014, Pages 14678-14681

  Qiao, Yuan ^a   Lebar, Matthew D ^b   Schirner, Kathrin ^c   Schaefer, Kaitlin ^b   Tsukamoto, Hirokazu ^b   Kahne, Daniel ^a,b   Walker, Suzanne ^a,c  

^a HARVARD UNIVERSITY   (United States)

^b HARVARD UNIVERSITY   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PEPTIDOGLYCAN PRECURSORS; TRANSPEPTIDASE;

AMINO ACID; BACITRACIN; BAMBERMYCIN; FOSFOMYCIN; GAMMA GLUTAMYLTRANSFERASE; KANAMYCIN; PENICILLIN BINDING PROTEIN; PENICILLIN BINDING PROTEIN 4; PEPTIDOGLYCAN; UNCLASSIFIED DRUG; VANCOMYCIN; BACTERIAL PROTEIN; LIPID I; MONOSACCHARIDE; MURAMYL-NAC-(PENTAPEPTIDE)PYROPHOSPHORYL-UNDECAPRENOL; OLIGOPEPTIDE; PEPTIDYLTRANSFERASE; URIDINE DIPHOSPHATE N ACETYLMURAMIC ACID;

ARTICLE; ENZYME ACTIVITY; IN VITRO STUDY; NONHUMAN; STAPHYLOCOCCUS AUREUS; ANALOGS AND DERIVATIVES; CHEMISTRY; METABOLISM; PROTEIN TERTIARY STRUCTURE;

BACTERIAL PROTEINS; MONOSACCHARIDES; OLIGOPEPTIDES; PENICILLIN-BINDING PROTEINS; PEPTIDOGLYCAN; PEPTIDYL TRANSFERASES; PROTEIN STRUCTURE, TERTIARY; STAPHYLOCOCCUS AUREUS; URIDINE DIPHOSPHATE N-ACETYLMURAMIC ACID;

EID: 84908440173     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja508147s     Document Type: Article

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