Induction of diverse cardiac cell types by reprogramming fibroblasts with cardiac transcription factors

Development (Cambridge)

Volumn 141, Issue 22, 2014, Pages 4267-4278

  Nam, Young Jae ^a,b   Lubczyk, Christina ^c   Bhakta, Minoti ^c   Zang, Tong ^a   Fernandez Perez, Antonio ^c   McAnally, John ^a   Bassel Duby, Rhonda ^a   Olson, Eric N ^a,d   Munshi, Nikhil V ^a,c  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d UT Southwestsern Medical Center   (United States)

Author keywords

Cardiomyocyte; Direct reprogramming; Mouse; Pacemaker

Indexed keywords

MYOCYTE ENHANCER FACTOR 2; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR HAND 2; TRANSCRIPTION FACTOR TBX5; UNCLASSIFIED DRUG; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; GATA4 PROTEIN, MOUSE; GREEN FLUORESCENT PROTEIN; HAND2 PROTEIN, MOUSE; HCN4 PROTEIN, MOUSE; HYPERPOLARIZATION ACTIVATED CYCLIC NUCLEOTIDE GATED CHANNEL; MEF2C PROTEIN, MOUSE; PRIMER DNA; T BOX TRANSCRIPTION FACTOR; T-BOX TRANSCRIPTION FACTOR 5;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELLS BY BODY ANATOMY; FIBROBLAST; HEART DEVELOPMENT; HEART MUSCLE CELL; MOUSE; NONHUMAN; PACEMAKER; PHENOTYPE; PROTEIN EXPRESSION; SARCOMERE; SINGLE CELL ANALYSIS; STEM CELL; ACTION POTENTIAL; ANALYSIS OF VARIANCE; ANIMAL; CARDIAC MUSCLE CELL; CELL DIFFERENTIATION; CYTOLOGY; EMBRYO INDUCTION; EMBRYOLOGY; GENETICS; HEART; IMMUNOHISTOCHEMISTRY; METABOLISM; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION;

ACTION POTENTIALS; ANALYSIS OF VARIANCE; ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL DIFFERENTIATION; DNA PRIMERS; EMBRYONIC INDUCTION; FIBROBLASTS; GATA4 TRANSCRIPTION FACTOR; GREEN FLUORESCENT PROTEINS; HEART; HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNELS; IMMUNOHISTOCHEMISTRY; MEF2 TRANSCRIPTION FACTORS; MICE; MYOCYTES, CARDIAC; REAL-TIME POLYMERASE CHAIN REACTION; T-BOX DOMAIN PROTEINS; TRANSCRIPTION FACTORS;

EID: 84908431264     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.114025     Document Type: Article

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