Antioxidant properties of UCP1 are evolutionarily conserved in mammals and buffer mitochondrial reactive oxygen species

Free Radical Biology and Medicine

Volumn 77, Issue , 2014, Pages 210-216

  Oelkrug, Rebecca ^a,b   Goetze, Nadja ^a,c   Meyer, Carola W ^a,d   Jastroch, Martin ^a,d  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b UNIVERSITY OF BONN   (Germany)

^c MAX PLANCK INSTITUTE OF EXPERIMENTAL MEDICINE   (Germany)

^d INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

Afrotheria; Brown adipose tissue; Echinops telfairi; Evolution; Free radicals; Membrane potential; Mild uncoupling; Protoendothermic; Reactive oxygen species; Uncoupling protein 1

Indexed keywords

BUFFER; HYDROGEN PEROXIDE; REACTIVE OXYGEN METABOLITE; UNCOUPLING PROTEIN 1; ION CHANNEL; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL UNCOUPLING PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BROWN ADIPOSE TISSUE; COLD; COLD ACCLIMATIZATION; ECHINOPS TELFAIRI; EVOLUTION; MAMMAL; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; NONHUMAN; NONSHIVERING THERMOGENESIS; OXIDATION; OXIDATIVE PHOSPHORYLATION UNCOUPLING; OXIDATIVE STRESS; TENREC; ACCLIMATIZATION; ANIMAL; INSECTIVORA; METABOLISM; MITOCHONDRION; PHYSIOLOGY;

ACCLIMATIZATION; ADIPOSE TISSUE, BROWN; ANIMALS; BIOLOGICAL EVOLUTION; INSECTIVORA; ION CHANNELS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

EID: 84908398137     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2014.09.004     Document Type: Article

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