Activation of calcineurin underlies altered trafficking of α2 subunit containing GABAA receptors during prolonged epileptiform activity

Neuropharmacology

Volumn 88, Issue , 2015, Pages 82-90

  Eckel, Ramona ^a,b   Szulc, Blanka ^b   Walker, Matthew C ^a   Kittler, Josef T ^b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Calcium signaling; Epilepsy; GABAA receptor; Surface stability; Trafficking

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR ALPHA2; BENZODIAZEPINE; CALCINEURIN; MAGNESIUM; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR; CALCIUM;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; EPILEPTIC DISCHARGE; EPILEPTIC STATE; HIPPOCAMPUS; IN VITRO STUDY; MOLECULAR IMAGING; MOLECULAR MECHANICS; NONHUMAN; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN STABILITY; PROTEIN TRANSPORT; RAT; ANIMAL; CELL MEMBRANE; GENETIC TRANSFECTION; GENETICS; INTRACELLULAR SPACE; MAGNESIUM DEFICIENCY; METABOLISM; NERVE CELL;

ANIMALS; CALCINEURIN; CALCIUM; CELL MEMBRANE; HIPPOCAMPUS; INTRACELLULAR SPACE; MAGNESIUM DEFICIENCY; NEURONS; RATS; RECEPTORS, GABA-A; RECEPTORS, N-METHYL-D-ASPARTATE; STATUS EPILEPTICUS; TRANSFECTION;

EID: 84908376956     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2014.09.014     Document Type: Article

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