Epileptogenesis causes acute and chronic increases in GABAA receptor endocytosis that contributes to the induction and maintenance of seizures in the hippocampal culture model of acquired epilepsy

Journal of Pharmacology and Experimental Therapeutics

Volumn 310, Issue 3, 2004, Pages 871-880

  Blair, Robert E ^a   Sombati, Sompong ^a   Lawrence, David C ^a   McCay, Brendan D ^a   DeLorenzo, Robert J ^a,b  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; FLUNITRAZEPAM; MAGNESIUM ION; RECEPTOR SUBUNIT;

ANIMAL TISSUE; ANTIBODY LABELING; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG RECEPTOR BINDING; ENDOCYTOSIS; EPILEPSY; EPILEPTOGENESIS; GABAERGIC TRANSMISSION; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; INTERNALIZATION; NERVE CELL CULTURE; NEWBORN; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT; RECEPTOR DOWN REGULATION; RECEPTOR INTRINSIC ACTIVITY; SEIZURE;

ANIMALS; CELLS, CULTURED; ENDOCYTOSIS; EPILEPSY; HIPPOCAMPUS; MEMBRANE PROTEINS; PROTEIN SUBUNITS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; SEIZURES; SYNAPTOPHYSIN;

EID: 4243084364     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.104.068478     Document Type: Article

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