Bisphenol a enhances adipogenic differentiation of human adipose stromal/stem cells

Journal of Molecular Endocrinology

Volumn 53, Issue 3, 2014, Pages 345-353

  Ohlstein, Jason F ^a   Strong, Amy L ^a   McLachlan, John A ^a   Gimble, Jeffrey M ^a   Burow, Matthew E ^b   Bunnell, Bruce A ^a  

^a TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TULANE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

Adipogenesis; Adipose stromal stem cell; Bisphenol A (BPA); Endocrine disrupters; Estrogen receptor

Indexed keywords

4,4' ISOPROPYLIDENEDIPHENOL; CCAAT ENHANCER BINDING PROTEIN ALPHA; DIMETHYL SULFOXIDE; DUAL LEUCINE ZIPPER BEARING KINASE; ESTROGEN RECEPTOR ALPHA; FULVESTRANT; LIPOPROTEIN LIPASE; PHOSPHOTRANSFERASE; UNCLASSIFIED DRUG; BENZHYDRYL DERIVATIVE; PHENOL DERIVATIVE;

ADIPOCYTE; ADIPOGENESIS; ADIPOSE TISSUE CELL; ADULT; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION ASSAY; CONTROLLED STUDY; CYTOTOXICITY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; OPTICAL DENSITY; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEM CELL; STROMA CELL; WESTERN BLOTTING; ADIPOSE TISSUE; ADULT STEM CELL; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; MIDDLE AGED; PHYSIOLOGY; UPREGULATION;

ADIPOCYTES; ADIPOGENESIS; ADIPOSE TISSUE; ADULT; ADULT STEM CELLS; BENZHYDRYL COMPOUNDS; CELL DIFFERENTIATION; CELLS, CULTURED; FEMALE; HUMANS; MIDDLE AGED; PHENOLS; STROMAL CELLS; UP-REGULATION;

EID: 84908376826     PISSN: 09525041     EISSN: 14796813     Source Type: Journal    
DOI: 10.1530/JME-14-0052     Document Type: Article

References (30)

1. Ali AT, Hochfeld WE, Myburgh R & Pepper MS 2013 Adipocyte and adipogenesis. European Journal of Cell Biology 92 229–236. (doi:10.1016/j.ejcb.2013.06.001)
2. Biedermann S, Tschudin P & Grob K 2010 Transfer of bisphenol A from thermal printer paper to the skin. Analytical and Bioanalytical Chemistry 398 571–576. (doi:10.1007/s00216-010-3936-9)
3. Bourin P, Bunnell BA, Casteilla L, Dominici M, Katz AJ, March KL, Redl H, Rubin JP, Yoshimura K & Gimble JM 2013 Stromal cells from the adipose tissue-derived stromal vascular fraction and culture expanded adipose tissue-derived stromal/stem cells: a joint statement of the International Federation for Adipose Therapeutics and Science (IFATS) and the International Society for Cellular Therapy (ISCT). Cytotherapy 15 641–648. (doi:10.1016/j.jcyt.2013.02.006)
4. Chamorro-Garcia R, Kirchner S, Li X, Janesick A, Casey SC, Chow C & Blumberg B 2012 Bisphenol A diglycidyl ether induces adipogenic differentiation of multipotent stromal stem cells through a peroxisome proliferator-activated receptor gamma-independent mechanism. Environmental Health Perspectives 120 984–989. (doi:10.1289/ehp.1205063)
5. Chen Zee E, Cornet P, Lazimi G, Rondet C, Lochard M, Magnier AM & Ibanez G 2013 Impact of endocrine disrupting chemicals on birth outcomes. Gynécologie, Obstétrique & Fertilité 41 601–610. (doi:10.1016/j.gyobfe.2013.08.012)
6. Couture JP & Blouin R 2011 The DLK gene is a transcriptional target of PPARg. Biochemical Journal 438 93–101. (doi:10.1042/BJ20101840)
7. De Pergola G & Silvestris F 2013 Obesity as a major risk factor for cancer. Journal of Obesity 2013 291546. (doi:10.1155/2013/291546)
8. Fernandez MF, Arrebola JP, Taoufiki J, Navalon A, Ballesteros O, Pulgar R, Vilchez JL & Olea N 2007 Bisphenol-A and chlorinated derivatives in adipose tissue of women. Reproductive Toxicology 24 259–264. (doi:10.1016/j.reprotox.2007.06.007)
9. Hawsawi Y, El-Gendy R, Twelves C, Speirs V & Beattie J 2013 Insulin-like growth factor – oestradiol crosstalk and mammary gland tumouri-genesis. Biochimica et Biophysica Acta 1836 345–353. (doi:10.1016/j.bbcan.2013.10.005)
10. Hugo ER, Brandebourg TD, Woo JG, Loftus J, Alexander JW & Ben-Jonathan N 2008 Bisphenol A at environmentally relevant doses inhibits adiponectin release from human adipose tissue explants and adipocytes. Environmental Health Perspectives 116 1642–1647. (doi:10.1289/ehp.11537)
11. Khalil N, Ebert JR, Wang L, Belcher S, Lee M, Czerwinski SA & Kannan K 2013 Bisphenol A and cardiometabolic risk factors in obese children. Science of the Total Environment 470–471C 726–732. (doi:10.1016/j.scitotenv.2013.09.088)
12. 9K and progesterone receptor via an estrogen receptor pathway in rat pituitary GH3 cells. Journal of Physiology and Pharmacology 63 445–455.
13. Le HH, Carlson EM, Chua JP & Belcher SM 2008 Bisphenol A is released from polycarbonate drinking bottles and mimics the neurotoxic actions of estrogen in developing cerebellar neurons. Toxicology Letters 2 149–156. (doi:10.1016/j.toxlet.2007.11.001)
14. Li Y, Burns KA, Arao Y, Luh CJ & Korach KS 2012 Differential estrogenic actions of endocrine-disrupting chemicals bisphenol A, bisphenol AF, and zearalenone through estrogen receptor a and b in vitro. Environmental Health Perspectives 120 1029–1035. (doi:10.1289/ehp.1104689)
15. Liao C & Kannan K 2011 Widespread occurrence of bisphenol A in paper and paper products: implications for human exposure. Environmental Science & Technology 45 9372–9379. (doi:10.1021/es202507f)
16. Liao C, Liu F & Kannan K 2012 Bisphenol S, a new bisphenol analogue, in paper products and currency bills and its association with bisphenol A residues. Environmental Science & Technology 46 6515–6522. (doi:10.1021/es300876n)
17. Linehan C, Gupta S, Samali A & O’Connor L 2012 Bisphenol A-mediated suppression of LPL gene expression inhibits triglyceride accumulation during adipogenic differentiation of human adult stem cells. PLoS ONE 7 e36109. (doi:10.1371/journal.pone.0036109)
18. Maserejian NN, Shrader P, Brown OA, Trachtenberg FL, Soncini J, Hauser R & Shenker BJ 2014 Dental sealants and composite restorations and longitudinal changes in immune function markers in children. International Journal of Paediatric Dentistry 24 215–225. (doi:10.1111/ipd.12064)
19. Masuno H, Iwanami J, Kidani T, Sakayama K & Honda K 2005 Bisphenol A accelerates terminal differentiation of 3T3-L1 cells into adipocytes through the phosphatidylinositol 3-kinase pathway. Toxicological Sciences 84 319–327. (doi:10.1093/toxsci/kfi088)
20. Melzer D, Harries L, Cipelli R, Henley W, Money C, McCormack P, Young A, Guralnik J, Ferrucci L, Bandinelli S et al. 2011 Bisphenol A exposure is associated with in vivo estrogenic gene expression in adults. Environmental Health Perspectives 119 1788–1793. (doi:10.1289/ehp.1103809)
21. Rochester JR 2013 Bisphenol A and human health: a review of the literature. Reproductive Toxicology 42C 132–155. (doi:10.1016/j.reprotox.2013.08.008)
22. vom Saal FS & Hughes C 2005 An extensive new literature concerning low-dose effects of bisphenol A shows the need for a new risk assessment. Environmental Health Perspectives 113 926–933. (doi:10.1289/ehp.7713)
23. Sargis RM, Johnson DN, Choudhury RA & Brady MJ 2010 Environmental endocrine disruptors promote adipogenesis in the 3T3-L1 cell line through glucocorticoid receptor activation. Obesity 18 1283–1288. (doi:10.1038/oby.2009.419)
24. Somm E, Schwitzgebel VM, Toulotte A, Cederroth CR, Combescure C, Nef S, Aubert ML & Huppi PS 2009 Perinatal exposure to bisphenol a alters early adipogenesis in the rat. Environmental Health Perspectives 117 1549–1555. (doi:10.1289/ehp.11342)
25. Strong A, Semon J, Strong T, Santoke T, Zhang S, McFerrin H, Gimble J & Bunnell B 2012 Obesity-associated dysregulation of calpastatin and MMP-15 in adipose-derived stromal cells results in their enhanced invasion. Stem Cells 30 2773–2783. (doi:10.1002/stem.1229)
26. Strong A, Strong T, Rhodes L, Semon J, Zhang X, Shi Z, Zhang S, Gimble J, Burow M & Bunnell B 2013 Obesity associated alterations in the biology of adipose stem cells mediate enhanced tumorigenesis by estrogen dependent pathways. Breast Cancer Research 15 R102. (doi:10.1186/bcr3569)
27. Surmacz E & Bartucci M 2004 Role of estrogen receptor alpha in modulating IGF-I receptor signaling and function in breast cancer. Journal of Experimental & Clinical Cancer Research 23 385–394.
28. Welshons WV, Nagel SC & vom Saal FS 2006 Large effects from small exposures. III. Endocrine mechanisms mediating effects of bisphenol A at levels of human exposure. Endocrinology 147 S56–S69. (doi:10.1210/en.2005-1159)
29. 2C fluxes and prolactin release in GH3/B6 pituitary tumor cells. Environmental Health Perspectives 113 431–439. (doi:10.1289/ehp.7505)
30. Xie L & Wang W 2013 Weight control and cancer preventive mechanisms: role of insulin growth factor-1-mediated signaling pathways. Experimental Biology and Medicine 238 127–132. (doi:10.1177/1535370213477602)