LOX-1 - Dependent mitochondrial DNA damage and NLRP3 activation during systemic inflammation in mice

Biochemical and Biophysical Research Communications

Volumn 451, Issue 4, 2014, Pages 637-643

  Ding, Zufeng ^a,b   Liu, Shijie ^a,c   Wang, Xianwei ^a   Theus, Sue ^a   Fan, Yubo ^b   Deng, Xiaoyan ^b   Mehta, Jawahar L ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b BEIHANG UNIVERSITY   (China)

^c UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

LOX 1; Mitochondrial DNA damage; NLRP3 inflammasome

Indexed keywords

CD45 ANTIGEN; CD68 ANTIGEN; CRYOPYRIN; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; MITOCHONDRIAL DNA; OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR 1; THIOGLYCOLIC ACID; CARRIER PROTEIN; CIAS1 PROTEIN, MOUSE; INTERLEUKIN 1BETA CONVERTING ENZYME; THIOGLYCOLIC ACID DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; KIDNEY; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; SPLEEN; WESTERN BLOTTING; WILD TYPE; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; GENETICS; LOX-1; MALE; METABOLISM; MITOCHONDRIAL DNA DAMAGE; NLRP3 INFLAMMASOME; PHYSIOLOGY;

LOX-1; MITOCHONDRIAL DNA DAMAGE; NLRP3 INFLAMMASOME;

ANIMALS; CARRIER PROTEINS; CASPASE 1; DNA DAMAGE; DNA, MITOCHONDRIAL; INFLAMMASOMES; INFLAMMATION; INTERLEUKIN-18; INTERLEUKIN-1BETA; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; SCAVENGER RECEPTORS, CLASS E; THIOGLYCOLATES;

EID: 84908375484     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.08.034     Document Type: Article

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