A near-infrared fluorescent voltage-sensitive dye allows for moderate-throughput electrophysiological analyses of human induced pluripotent stem cell-derived cardiomyocytes

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 307, Issue 9, 2014, Pages H1370-H1377

  Lopez Izquierdo, Angelica ^a   Warren, Mark ^a   Riedel, Michael ^b   Cho, Scott ^a   Lai, Shuping ^b   Lux, Robert L ^a   Spitzer, Kenneth W ^a   Benjamin, Ivor J ^b   Tristani Firouzi, Martin ^a   Jou, Chuanchau J ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Acquired long QT syndrome; Optical action potential; Preclinical drug screening; QT prolongation; Stem cell model

Indexed keywords

1 (4 SULFANATOBUTYL) 4 [BETA[2 (DI N BUTYLAMINO) 6 NAPHTHYL]BUTADIENYL]QUINOLINIUM BETAINE; BETAINE DERIVATIVE; FLUORESCENT DYE; UNCLASSIFIED DRUG; 1-(4-SULFANATOBUTYL)-4-(BETA-(2-(DI-N-BUTYLAMINO)-6-NAPHTHYL)BUTADIENYL)QUINOLINIUM BETAINE; 2 NAPHTHYLAMINE; QUINOLINE DERIVATIVE;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL STRUCTURE; HEART ELECTROPHYSIOLOGY; HEART MUSCLE CELL; HEART MUSCLE FIBER MEMBRANE POTENTIAL; HEART REPOLARIZATION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PLURIPOTENT STEM CELL; QT INTERVAL; SIGNAL NOISE RATIO; VOLTAGE SENSITIVE DYE IMAGING; ACTION POTENTIAL; ANALOGS AND DERIVATIVES; CHEMISTRY; CYTOLOGY; INFRARED RADIATION; PHYSIOLOGY; PROCEDURES;

2-NAPHTHYLAMINE; ACTION POTENTIALS; CELL DIFFERENTIATION; FLUORESCENT DYES; HUMANS; INDUCED PLURIPOTENT STEM CELLS; INFRARED RAYS; MYOCYTES, CARDIAC; QUINOLINIUM COMPOUNDS; VOLTAGE-SENSITIVE DYE IMAGING;

EID: 84908375059     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00344.2014     Document Type: Article

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