Functional and pharmacological analysis of cardiomyocytes differentiated from human peripheral blood mononuclear-derived pluripotent stem cells

Stem Cell Reports

Volumn 3, Issue 1, 2014, Pages 131-141

  Riedel, Michael ^a   Jou, Chuanchau J ^b   Lai, Shuping ^a   Lux, Robert L ^b   Moreno, Alonso P ^b   Spitzer, Kenneth W ^b   Christians, Elizabeth ^a   Tristani Firouzi, Martin ^b   Benjamin, Ivor J ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; ALPHA FETOPROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2;

ACTIVATION RECOVERY INTERVAL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL DIFFERENTIATION; CONTROLLED STUDY; ELECTROPHYSIOLOGY; ELECTROSTIMULATION; GENE EXPRESSION; HEART MUSCLE CELL; HEART MUSCLE FIBER MEMBRANE POTENTIAL; HUMAN; HUMAN CELL; MONOLAYER CULTURE; PATCH CLAMP TECHNIQUE; PERIPHERAL BLOOD MONONUCLEAR CELL; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; SOMATIC CELL; ACTION POTENTIAL; ADULT; ANIMAL TISSUE; CASE REPORT; DRUG SCREENING; ELECTROPHYSIOLOGICAL PROCEDURES; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; KARYOTYPING; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MEMBRANE STEADY POTENTIAL; MOUSE; NONHUMAN; PERSONALIZED MEDICINE; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SEVERE COMBINED IMMUNODEFICIENCY; ANIMAL; CARDIAC MUSCLE CELL; CELL CULTURE; CYTOLOGY; INDUCED PLURIPOTENT STEM CELL; KARYOTYPE; MONONUCLEAR CELL; PHYSIOLOGY;

ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; ELECTROPHYSIOLOGY; FLOW CYTOMETRY; HUMANS; INDUCED PLURIPOTENT STEM CELLS; KARYOTYPE; LEUKOCYTES, MONONUCLEAR; MYOCYTES, CARDIAC;

EID: 84904258538     PISSN: 22136711     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.stemcr.2014.04.017     Document Type: Article

References (47)

1. O.A. Ajijola, D. Yagishita, K.J. Patel, M. Vaseghi, W. Zhou, K. Yamakawa, E. So, R.L. Lux, A. Mahajan, and K. Shivkumar Focal myocardial infarction induces global remodeling of cardiac sympathetic innervation: neural remodeling in a spatial context Am. J. Physiol. Heart Circ. Physiol. 305 2013 H1031 H1040
2. S.R. Braam, L. Tertoolen, S. Casini, E. Matsa, H.R. Lu, A. Teisman, R. Passier, C. Denning, D.J. Gallacher, R. Towart, and C.L. Mummery Repolarization reserve determines drug responses in human pluripotent stem cell derived cardiomyocytes Stem Cell Res. (Amst.) 10 2013 48 56
3. M.E. Brown, E. Rondon, D. Rajesh, A. Mack, R. Lewis, X. Feng, L.J. Zitur, R.D. Learish, and E.F. Nuwaysir Derivation of induced pluripotent stem cells from human peripheral blood T lymphocytes PLoS ONE 5 2010 e11373
4. B.J. Brundel, I.C. Van Gelder, R.H. Henning, A.E. Tuinenburg, M. Wietses, J.G. Grandjean, A.A. Wilde, W.H. Van Gilst, and H.J. Crijns Alterations in potassium channel gene expression in atria of patients with persistent and paroxysmal atrial fibrillation: differential regulation of protein and mRNA levels for K+ channels J. Am. Coll. Cardiol. 37 2001 926 932 (Pubitemid 32202465)
5. B.J. Brundel, H.H. Kampinga, and R.H. Henning Calpain inhibition prevents pacing-induced cellular remodeling in a HL-1 myocyte model for atrial fibrillation Cardiovasc. Res. 62 2004 521 528 (Pubitemid 38648966)
6. B.J. Brundel, R.H. Henning, L. Ke, I.C. van Gelder, H.J. Crijns, and H.H. Kampinga Heat shock protein upregulation protects against pacing-induced myolysis in HL-1 atrial myocytes and in human atrial fibrillation J. Mol. Cell. Cardiol. 41 2006 555 562 (Pubitemid 44344288)
7. M. Chinushi, M. Tagawa, H. Kasai, T. Washizuka, A. Abe, H. Furushima, and Y. Aizawa Correlation between the effective refractory period and activation-recovery interval calculated from the intracardiac unipolar electrogram of humans with and without dl-sotalol treatment Jpn. Circ. J. 65 2001 702 706
8. J.M. Churko, P.W. Burridge, and J.C. Wu Generation of human iPSCs from human peripheral blood mononuclear cells using non-integrative Sendai virus in chemically defined conditions Methods Mol. Biol. 1036 2013 81 88
9. S.J. Compton, R.L. Lux, M.R. Ramsey, K.R. Strelich, M.C. Sanguinetti, L.S. Green, M.T. Keating, and J.W. Mason Genetically defined therapy of inherited long-QT syndrome. Correction of abnormal repolarization by potassium Circulation 94 1996 1018 1022 (Pubitemid 26292855)
10. M.S. Fuller, G. Sándor, B. Punske, B. Taccardi, R.S. MacLeod, P.R. Ershler, L.S. Green, and R.L. Lux Estimates of repolarization and its dispersion from electrocardiographic measurements: direct epicardial assessment in the canine heart J. Electrocardiol. 33 2000 171 180 (Pubitemid 30257788)
11. M.S. Fuller, G. Sándor, B. Punske, B. Taccardi, R.S. MacLeod, P.R. Ershler, L.S. Green, and R.L. Lux Estimates of repolarization dispersion from electrocardiographic measurements Circulation 102 2000 685 691 (Pubitemid 30640670)
12. C.W. Haws, and R.L. Lux Correlation between in vivo transmembrane action potential durations and activation-recovery intervals from electrograms. Effects of interventions that alter repolarization time Circulation 81 1990 281 288 (Pubitemid 20031792)
13. D. Hockemeyer, F. Soldner, E.G. Cook, Q. Gao, M. Mitalipova, and R. Jaenisch A drug-inducible system for direct reprogramming of human somatic cells to pluripotency Cell Stem Cell 3 2008 346 353
14. I. Itzhaki, L. Maizels, I. Huber, L. Zwi-Dantsis, O. Caspi, A. Winterstern, O. Feldman, A. Gepstein, G. Arbel, and H. Hammerman et al. Modelling the long QT syndrome with induced pluripotent stem cells Nature 471 2011 225 229
15. I. Itzhaki, L. Maizels, I. Huber, A. Gepstein, G. Arbel, O. Caspi, L. Miller, B. Belhassen, E. Nof, M. Glikson, and L. Gepstein Modeling of catecholaminergic polymorphic ventricular tachycardia with patient-specific human-induced pluripotent stem cells J. Am. Coll. Cardiol. 60 2012 990 1000
16. C.Y. Ivashchenko, G.C. Pipes, I.M. Lozinskaya, Z. Lin, X. Xiaoping, S. Needle, E.T. Grygielko, E. Hu, J.R. Toomey, J.J. Lepore, and R.N. Willette Human-induced pluripotent stem cell-derived cardiomyocytes exhibit temporal changes in phenotype Am. J. Physiol. Heart Circ. Physiol. 305 2013 H913 H922
17. R. Kato, N. Venkatesh, K. Kamiya, S. Yabek, R. Kannan, and B.N. Singh Electrophysiologic effects of desethylamiodarone, an active metabolite of amiodarone: comparison with amiodarone during chronic administration in rabbits Am. Heart J. 115 1988 351 359 (Pubitemid 18043281)
18. L. Ke, R.A. Meijering, F. Hoogstra-Berends, K. Mackovicova, M.J. Vos, I.C. Van Gelder, R.H. Henning, H.H. Kampinga, and B.J. Brundel HSPB1, HSPB6, HSPB7 and HSPB8 protect against RhoA GTPase-induced remodeling in tachypaced atrial myocytes PLoS ONE 6 2011 e20395
19. I. Kodama, K. Kamiya, H. Honjo, and J. Toyama Acute and chronic effects of amiodarone on mammalian ventricular cells Jpn. Heart J. 37 1996 719 730 (Pubitemid 26358663)
20. I. Kodama, K. Kamiya, and J. Toyama Cellular electropharmacology of amiodarone Cardiovasc. Res. 35 1997 13 29 (Pubitemid 27374736)
21. A.L. Lahti, V.J. Kujala, H. Chapman, A.P. Koivisto, M. Pekkanen-Mattila, E. Kerkelä, J. Hyttinen, K. Kontula, H. Swan, and B.R. Conklin et al. Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture Dis. Model. Mech. 5 2012 220 230
22. P. Liang, F. Lan, A.S. Lee, T. Gong, V. Sanchez-Freire, Y. Wang, S. Diecke, K. Sallam, J.W. Knowles, and P.J. Wang et al. Drug screening using a library of human induced pluripotent stem cell-derived cardiomyocytes reveals disease-specific patterns of cardiotoxicity Circulation 127 2013 1677 1691
23. W.E. Lowry, L. Richter, R. Yachechko, A.D. Pyle, J. Tchieu, R. Sridharan, A.T. Clark, and K. Plath Generation of human induced pluripotent stem cells from dermal fibroblasts Proc. Natl. Acad. Sci. USA 105 2008 2883 2888 (Pubitemid 351723638)
24. L.C. Mace, L.V. Yermalitskaya, Y. Yi, Z. Yang, A.M. Morgan, and K.T. Murray Transcriptional remodeling of rapidly stimulated HL-1 atrial myocytes exhibits concordance with human atrial fibrillation J. Mol. Cell. Cardiol. 47 2009 485 492
25. D. Malan, S. Friedrichs, B.K. Fleischmann, and P. Sasse Cardiomyocytes obtained from induced pluripotent stem cells with long-QT syndrome 3 recapitulate typical disease-specific features in vitro Circ. Res. 109 2011 841 847
26. E. Matsa, D. Rajamohan, E. Dick, L. Young, I. Mellor, A. Staniforth, and C. Denning Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syndrome type 2 mutation Eur. Heart J. 32 2011 952 962
27. A. Moretti, M. Bellin, A. Welling, C.B. Jung, J.T. Lam, L. Bott-Flügel, T. Dorn, A. Goedel, C. Höhnke, and F. Hofmann et al. Patient-specific induced pluripotent stem-cell models for long-QT syndrome N. Engl. J. Med. 363 2010 1397 1409
28. E.G. Navarrete, P. Liang, F. Lan, V. Sanchez-Freire, C. Simmons, T. Gong, A. Sharma, P.W. Burridge, B. Patlolla, and A.S. Lee et al. Screening drug-induced arrhythmia events using human induced pluripotent stem cell-derived cardiomyocytes and low-impedance microelectrode arrays Circulation 128 Suppl 1 2013 S3 S13
29. F. Nosten, F.O. ter Kuile, C. Luxemburger, C. Woodrow, D.E. Kyle, T. Chongsuphajaisiddhi, and N.J. White Cardiac effects of antimalarial treatment with halofantrine Lancet 341 1993 1054 1056 (Pubitemid 23114398)
30. X.Y. Qi, Y.H. Yeh, L. Xiao, B. Burstein, A. Maguy, D. Chartier, L.R. Villeneuve, B.J. Brundel, D. Dobrev, and S. Nattel Cellular signaling underlying atrial tachycardia remodeling of L-type calcium current Circ. Res. 103 2008 845 854
31. A. Shiroshita-Takeshita, B.J. Brundel, and S. Nattel Atrial fibrillation: basic mechanisms, remodeling and triggers J. Interv. Card. Electrophysiol. 13 2005 181 193 (Pubitemid 41372065)
32. E.C. So, M.A. Sallin, X. Zhang, S.L. Chan, L. Sahni, D.H. Schulze, E. Davila, S.E. Strome, and A. Jain A high throughput method for enrichment of natural killer cells and lymphocytes and assessment of in vitro cytotoxicity J. Immunol. Methods 394 2013 40 48
33. C.A. Sommer, A.G. Sommer, T.A. Longmire, C. Christodoulou, D.D. Thomas, M. Gostissa, F.W. Alt, G.J. Murphy, D.N. Kotton, and G. Mostoslavsky Excision of reprogramming transgenes improves the differentiation potential of ips cells generated with a single excisable vector Stem Cells 28 2010 64 74
34. A.G. Sommer, S.S. Rozelle, S. Sullivan, J.A. Mills, S.M. Park, B.W. Smith, A.M. Iyer, D.L. French, D.N. Kotton, and P. Gadue et al. Generation of human induced pluripotent stem cells from peripheral blood using the STEMCCA lentiviral vector J. Vis. Exp. 68 2012 4327
35. K.W. Spitzer, N. Sato, H. Tanaka, L. Firek, M. Zaniboni, and W.R. Giles Electrotonic modulation of electrical activity in rabbit atrioventricular node myocytes Am. J. Physiol. 273 1997 H767 H776
36. J. Staerk, M.M. Dawlaty, Q. Gao, D. Maetzel, J. Hanna, C.A. Sommer, G. Mostoslavsky, and R. Jaenisch Reprogramming of human peripheral blood cells to induced pluripotent stem cells Cell Stem Cell 7 2010 20 24
37. K. Takahashi, and S. Yamanaka Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors Cell 126 2006 663 676 (Pubitemid 44233629)
38. K. Takahashi, K. Tanabe, M. Ohnuki, M. Narita, T. Ichisaka, K. Tomoda, and S. Yamanaka Induction of pluripotent stem cells from adult human fibroblasts by defined factors Cell 131 2007 861 872 (Pubitemid 350138099)
39. M. Vaseghi, K. Yamakawa, A. Sinha, E.L. So, W. Zhou, O.A. Ajijola, R.L. Lux, M. Laks, K. Shivkumar, and A. Mahajan Modulation of regional dispersion of repolarization and T-peak to T-end interval by the right and left stellate ganglia Am. J. Physiol. Heart Circ. Physiol. 305 2013 H1020 H1030
40. Z. Yang, W. Shen, J.N. Rottman, J.P. Wikswo, and K.T. Murray Rapid stimulation causes electrical remodeling in cultured atrial myocytes J. Mol. Cell. Cardiol. 38 2005 299 308 (Pubitemid 40215199)
41. M. Yazawa, B. Hsueh, X. Jia, A.M. Pasca, J.A. Bernstein, J. Hallmayer, and R.E. Dolmetsch Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome Nature 471 2011 230 234
42. J. Yu, M.A. Vodyanik, K. Smuga-Otto, J. Antosiewicz-Bourget, J.L. Frane, S. Tian, J. Nie, G.A. Jonsdottir, V. Ruotti, and R. Stewart et al. Induced pluripotent stem cell lines derived from human somatic cells Science 318 2007 1917 1920
43. A.M. Yue, J.R. Paisey, S. Robinson, T.R. Betts, P.R. Roberts, and J.M. Morgan Determination of human ventricular repolarization by noncontact mapping: validation with monophasic action potential recordings Circulation 110 2004 1343 1350 (Pubitemid 39238011)
44. Q. Zhang, J. Jiang, P. Han, Q. Yuan, J. Zhang, X. Zhang, Y. Xu, H. Cao, Q. Meng, and L. Chen et al. Direct differentiation of atrial and ventricular myocytes from human embryonic stem cells by alternating retinoid signals Cell Res. 21 2011 579 587
45. J. Zhang, M. Klos, G.F. Wilson, A.M. Herman, X. Lian, K.K. Raval, M.R. Barron, L. Hou, A.G. Soerens, and J. Yu et al. Extracellular matrix promotes highly efficient cardiac differentiation of human pluripotent stem cells: the matrix sandwich method Circ. Res. 111 2012 1125 1136
46. W.Z. Zhu, B. Van Biber, and M.A. Laflamme Methods for the derivation and use of cardiomyocytes from human pluripotent stem cells Methods Mol. Biol. 767 2011 419 431
47. L. Zwi, O. Caspi, G. Arbel, I. Huber, A. Gepstein, I.H. Park, and L. Gepstein Cardiomyocyte differentiation of human induced pluripotent stem cells Circulation 120 2009 1513 1523