Kaposi's Sarcoma-associated Herpesvirus (KSHV) oncoprotein K13 bypasses TRAFs and directly interacts with the IκB kinase complex to selectively activate NF-κB without JNK activation

Journal of Biological Chemistry

Volumn 282, Issue 34, 2007, Pages 24858-24865

  Matta, Hittu ^a   Mazzacurati, Lucia ^a   Schamus, Sandra ^a   Yang, Tianbing ^b   Sun, Qinmiao ^c   Chaudhary, Preet M ^a,b  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^c UNIVERSITY OF TEXAS AT DALLAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

KAPOSI'S SARCOMA-ASSOCIATED HERPESVIRUS; KINASE COMPLEX; SIGNALING PATHWAY; VIRAL PATHOGENESIS;

CELL DEATH; GENE EXPRESSION; MUTAGENESIS; TUMORS;

ONCOGENIC VIRUSES;

I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; KAPOSI SARCOMA ASSOCIATED HERPESVIRUS ONCOPROTEIN VFLIP K13; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 3; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ARTICLE; HUMAN; HUMAN CELL; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN STRUCTURE;

AMINO ACID MOTIFS; CELL LINE; HERPESVIRUS 8, HUMAN; HUMANS; I-KAPPA B KINASE; IMMUNOPRECIPITATION; MAP KINASE KINASE 4; MODELS, MOLECULAR; NF-KAPPA B; PLASMIDS; PROTEIN CONFORMATION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; U937 CELLS; VIRAL PROTEINS;

HERPESVIRIDAE;

EID: 34548364068     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M700118200     Document Type: Article

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