Molecular and structural transmembrane determinants critical for embedding claudin-5 into tight junctions reveal a distinct four-helix bundle arrangement

Biochemical Journal

Volumn 464, Issue , 2014, Pages 49-60

  Rossa, Jan ^a,b   Protze, Jonas ^a,b   Kern, Christian ^a   Piontek, Anna ^a   Günzel, Dorothee ^b   Krause, Gerd ^a   Piontek, Jörg ^b  

^a LEIBNIZ INSTITUT FÜR MOLEKULARE PHARMAKOLOGIE   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Claudin; Homology modelling; Membrane protein; Mutagenesis; Tight junction

Indexed keywords

ALANINE; CLAUDIN 3; CLAUDIN 5; CYSTEINE; ISOLEUCINE; LEUCINE; CLDN5 PROTEIN, MOUSE;

ARTICLE; CRYSTAL STRUCTURE; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; MOLECULAR MODEL; PROTEIN ASSEMBLY; PROTEIN FOLDING; PROTEIN MOTIF; STRUCTURAL BIOINFORMATICS; TIGHT JUNCTION; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; GENETICS; HEK293 CELL LINE; METABOLISM; MOLECULAR GENETICS; MOUSE; PROTEIN SECONDARY STRUCTURE;

AMINO ACID SEQUENCE; ANIMALS; CLAUDIN-5; HEK293 CELLS; HUMANS; MICE; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, SECONDARY; TIGHT JUNCTIONS;

EID: 84908371938     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20140431     Document Type: Article

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