Claudin-2 pore function requires an intramolecular disulfide bond between two conserved extracellular cysteines

American Journal of Physiology - Cell Physiology

Volumn 305, Issue 2, 2013, Pages

  Li, Jiahua ^a,b   Angelow, Susanne ^b   Linge, Anna ^b   Zhuo, Min ^a   Yu, Alan S L ^a,b  

^a UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Cysteines; Disulfide bond; Ion channel; Paracellular transport; Tight junction

Indexed keywords

ALANINE; CLAUDIN 2; CYSTEINE; SERINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOTINYLATION; CHANNEL GATING; DIMERIZATION; DISULFIDE BOND; EXTRACELLULAR SPACE; IMMUNOBLOTTING; IMMUNOFLUORESCENCE TEST; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PERMEABILITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN FUNCTION; SODIUM CONDUCTANCE; TIGHT JUNCTION;

CYSTEINES; DISULFIDE BOND; ION CHANNEL; PARACELLULAR TRANSPORT; TIGHT JUNCTION;

AMINO ACID SUBSTITUTION; ANIMALS; CELL LINE; CLAUDIN-2; CYSTEINE; DISULFIDES; DOGS; GENE EXPRESSION REGULATION; MADIN DARBY CANINE KIDNEY CELLS; MUTATION; PORINS;

EID: 84880163557     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00074.2013     Document Type: Article

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