Break-Induced Replication Requires DNA Damage-Induced Phosphorylation of Pif1 and Leads to Telomere Lengthening

PLoS Genetics

Volumn 10, Issue 10, 2014, Pages

  Vasianovich, Yulia ^a   Harrington, Lea A ^a,b   Makovets, Svetlana ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b INSTITUTE FOR RESEARCH IN IMMUNOLOGY AND CANCER   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DNA HELICASE; FUNGAL ENZYME; MEC1 PROTEIN; MEC3 PROTEIN; NUCLEOTIDYLTRANSFERASE; PIF1 HELICASE; POL32 PROTEIN; PROTEIN RAD9; RAD24 PROTEIN; RAD50 PROTEIN; RAD51 PROTEIN; RAD52 PROTEIN; UNCLASSIFIED DRUG; CELL CYCLE PROTEIN; CHECKPOINT KINASE 2; DNA LIGASE; DNA LIGASE (ATP); MEC1 PROTEIN, S CEREVISIAE; PIF1 PROTEIN, S CEREVISIAE; PROTEIN SERINE THREONINE KINASE; RAD53 PROTEIN, S CEREVISIAE; REPLICATION FACTOR C; RFC1 PROTEIN, S CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEIN; SIGNAL PEPTIDE; TELOMERASE;

ARTICLE; BREAK INDUCED REPLICATION; CONTROLLED STUDY; DNA DAMAGE; DNA DAMAGE CHECKPOINT; DNA REPLICATION; DOUBLE STRANDED DNA BREAK; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FUNGAL STRAIN; GENETIC RECOMBINATION; NONHUMAN; PROTEIN DNA INTERACTION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TELOMERE HOMEOSTASIS; GENETICS; METABOLISM; MUTATION; PHOSPHORYLATION; SINGLE STRANDED DNA BREAK;

CELL CYCLE PROTEINS; CHECKPOINT KINASE 2; DNA BREAKS, SINGLE-STRANDED; DNA DAMAGE; DNA HELICASES; DNA LIGASES; DNA REPLICATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MUTATION; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; REPLICATION PROTEIN C; SACCHAROMYCES CEREVISIAE PROTEINS; SIGNAL TRANSDUCTION; TELOMERASE; TELOMERE HOMEOSTASIS;

EID: 84908338099     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004679     Document Type: Article

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