P21Cip1/WAF1 expression is strongly associated with HPV-positive tonsillar carcinoma and a favorable prognosis

Modern Pathology

Volumn 22, Issue 5, 2009, Pages 686-698

  Hafkamp, Harriët C ^a   Moorenl, Jeroen J ^a   Claessen, Sandra Mh ^a   Klingenberg, Boris ^a   Voogd, Adri C ^a   Bot, Fredrik J ^b   Klussmann, J Peter ^c   Hopman, Anton Hn ^a   Manni, Johannes J ^a   Kremer, Bernd ^a   Ramaekers, Frans Cs ^a   Speel, Ernst Jan M ^a,b  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Cell cycle proteins; Human papillomavirus; P16INK4A; Tonsillar squamous cell carcinoma; Tumor size

Indexed keywords

CELL CYCLE PROTEIN; CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLIN DEPENDENT KINASE INHIBITOR 2A; KI 67 ANTIGEN; PROTEIN MDM2; PROTEIN P53; TUMOR MARKER; VIRUS DNA;

ADULT; ALCOHOL CONSUMPTION; ARTICLE; CANCER SIZE; CANCER SURVIVAL; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE MARKER; DOWN REGULATION; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN PAPILLOMAVIRUS TYPE 16; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; SMOKING; SQUAMOUS CELL CARCINOMA; SURVIVAL RATE; TONSIL CARCINOMA;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, SQUAMOUS CELL; CELL CYCLE PROTEINS; CYCLIN D1; CYCLIN-DEPENDENT KINASE INHIBITOR P21; FEMALE; GENE EXPRESSION; HUMANS; IMMUNOHISTOCHEMISTRY; KAPLAN-MEIERS ESTIMATE; MALE; MIDDLE AGED; PAPILLOMAVIRIDAE; PAPILLOMAVIRUS INFECTIONS; PROGNOSIS; RETINOBLASTOMA PROTEIN; SMOKING; TONSILLAR NEOPLASMS; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEIN P14ARF;

EID: 67349281254     PISSN: 08933952     EISSN: 15300285     Source Type: Journal    
DOI: 10.1038/modpathol.2009.23     Document Type: Article

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