메뉴 건너뛰기




Volumn , Issue 91, 2014, Pages

High efficiency differentiation of human pluripotent stem cells to cardiomyocytes and characterization by flow cytometry

Author keywords

Cardiomyocyte; Cellular Biology; Directed differentiation; Flow cytometry; Human induced pluripotent stem cell; IRX4; Issue 91; MCL2v; MLC2a; TNNI3; TNNT2

Indexed keywords

HOMEODOMAIN PROTEIN; IRX4 PROTEIN, HUMAN;

EID: 84908292226     PISSN: 1940087X     EISSN: None     Source Type: Journal    
DOI: 10.3791/52010     Document Type: Article
Times cited : (72)

References (65)
  • 1
    • 84863560929 scopus 로고    scopus 로고
    • Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling
    • Lian, X. et al. Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling. Proc Natl Acad Sci U S A. 109, E1848-1857, doi:10.1073/pnas.1200250109 1200250109 [pii] (2012).
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. E1848-1857
    • Lian, X.1
  • 2
    • 84872016692 scopus 로고    scopus 로고
    • Directed cardiomyocyte differentiation from human pluripotent stem cells by modulating Wnt/beta-catenin signaling under fully defined conditions
    • Lian, X. et al. Directed cardiomyocyte differentiation from human pluripotent stem cells by modulating Wnt/beta-catenin signaling under fully defined conditions. Nat Protoc. 8, 162-175, doi:10.1038/nprot.2012.150 nprot.2012.150 [pii] (2013).
    • (2013) Nat Protoc , vol.8 , pp. 162-175
    • Lian, X.1
  • 3
    • 84862907693 scopus 로고    scopus 로고
    • Production of de novo cardiomyocytes: Human pluripotent stem cell differentiation and direct reprogramming
    • Burridge, P. W., Keller, G., Gold, J. D., & Wu, J. C. Production of de novo cardiomyocytes: human pluripotent stem cell differentiation and direct reprogramming. Cell Stem Cell. 10, 16-28, doi:S1934-5909(11)00594-7 [pii] 10.1016/j.stem.2011.12.013 (2012).
    • (2012) Cell Stem Cell , vol.10 , pp. 16-28
    • Burridge, P.W.1    Keller, G.2    Gold, J.D.3    Wu, J.C.4
  • 4
    • 79954543387 scopus 로고    scopus 로고
    • A universal system for highly efficient cardiac differentiation of human induced pluripotent stem cells that eliminates interline variability
    • Burridge, P. W. et al. A universal system for highly efficient cardiac differentiation of human induced pluripotent stem cells that eliminates interline variability. PLoS One. 6, e18293, doi:10.1371/journal.pone.0018293 (2011).
    • (2011) PLoS One , vol.6 , pp. e18293
    • Burridge, P.W.1
  • 5
    • 44349175948 scopus 로고    scopus 로고
    • Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population
    • Yang, L. et al. Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population. Nature. 453, 524-528, doi:nature06894 [pii] 10.1038/nature06894 (2008).
    • (2008) Nature , vol.453 , pp. 524-528
    • Yang, L.1
  • 6
    • 79551597211 scopus 로고    scopus 로고
    • Stage-specific optimization of activin/nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell lines
    • Kattman, S. J. et al. Stage-specific optimization of activin/nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell lines. Cell Stem Cell. 8, 228-240, doi:S1934-5909(10)00703-4 [pii] 10.1016/j.stem.2010.12.008 (2011).
    • (2011) Cell Stem Cell , vol.8 , pp. 228-240
    • Kattman, S.J.1
  • 7
    • 80051796581 scopus 로고    scopus 로고
    • Small-molecule inhibitors of the Wnt pathway potently promote cardiomyocytes from human embryonic stem cell-derived mesoderm
    • Willems, E. et al. Small-molecule inhibitors of the Wnt pathway potently promote cardiomyocytes from human embryonic stem cell-derived mesoderm. Circ Res. 109, 360-364, doi:CIRCRESAHA.111.249540 [pii] 10.1161/CIRCRESAHA.111.249540 (2011).
    • (2011) Circ Res , vol.109 , pp. 360-364
    • Willems, E.1
  • 8
    • 34147124971 scopus 로고    scopus 로고
    • Improved human embryonic stem cell embryoid body homogeneity and cardiomyocyte differentiation from a novel V-96 plate aggregation system highlights interline variability
    • Burridge, P. W. et al. Improved human embryonic stem cell embryoid body homogeneity and cardiomyocyte differentiation from a novel V-96 plate aggregation system highlights interline variability. Stem Cells. 25, 929-938, doi:2006-0598 [pii] 10.1634/stemcells.2006-0598 (2007).
    • (2007) Stem Cells , vol.25 , pp. 929-938
    • Burridge, P.W.1
  • 9
    • 82355175128 scopus 로고    scopus 로고
    • NKX2-5(eGFP/w) hESCs for isolation of human cardiac progenitors and cardiomyocytes
    • Elliott, D. A. et al. NKX2-5(eGFP/w) hESCs for isolation of human cardiac progenitors and cardiomyocytes. Nat Methods. 8, 1037-1040, doi:10.1038/nmeth.1740 nmeth.1740 [pii] (2011).
    • (2011) Nat Methods , vol.8 , pp. 1037-1040
    • Elliott, D.A.1
  • 10
    • 34948891467 scopus 로고    scopus 로고
    • Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts
    • Laflamme, M. A. et al. Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts. Nat Biotechnol. 25, 1015-1024, doi:nbt1327 [pii] 10.1038/nbt1327 (2007).
    • (2007) Nat Biotechnol , vol.25 , pp. 1015-1024
    • Laflamme, M.A.1
  • 11
    • 79954418253 scopus 로고    scopus 로고
    • Direct differentiation of atrial and ventricular myocytes from human embryonic stem cells by alternating retinoid signals
    • Zhang, Q. et al. Direct differentiation of atrial and ventricular myocytes from human embryonic stem cells by alternating retinoid signals. Cell Res. 21, 579-587, doi:cr2010163 [pii] 10.1038/cr.2010.163 (2011).
    • (2011) Cell Res , vol.21 , pp. 579-587
    • Zhang, Q.1
  • 12
    • 80051847166 scopus 로고    scopus 로고
    • Efficient and scalable purification of cardiomyocytes from human embryonic and induced pluripotent stem cells by VCAM1 surface expression
    • Uosaki, H. et al. Efficient and scalable purification of cardiomyocytes from human embryonic and induced pluripotent stem cells by VCAM1 surface expression. PLoS One. 6, e23657, doi:10.1371/journal.pone.0023657 PONE-D-11-05980 [pii] (2011).
    • (2011) PLoS One , vol.6 , pp. e23657
    • Uosaki, H.1
  • 14
    • 84867746044 scopus 로고    scopus 로고
    • Extracellular matrix promotes highly efficient cardiac differentiation of human pluripotent stem cells: The matrix sandwich method
    • Zhang, J. et al. Extracellular matrix promotes highly efficient cardiac differentiation of human pluripotent stem cells: the matrix sandwich method. Circ Res. 111, 1125-1136, doi:10.1161/CIRCRESAHA.112.273144 CIRCRESAHA.112.273144 [pii] (2012).
    • (2012) Circ Res , vol.111 , pp. 1125-1136
    • Zhang, J.1
  • 15
    • 84886093510 scopus 로고    scopus 로고
    • Purification of cardiomyocytes from differentiating pluripotent stem cells using molecular beacons that target cardiomyocyte-specific mRNA
    • Ban, K. et al. Purification of cardiomyocytes from differentiating pluripotent stem cells using molecular beacons that target cardiomyocyte-specific mRNA. Circulation. 128, 1897-1909, doi:10.1161/CIRCULATIONAHA.113.004228 CIRCULATIONAHA.113.004228 [pii] (2013).
    • Circulation , vol.128 , pp. 1897-1909
    • Ban, K.1
  • 16
    • 0019789647 scopus 로고
    • Differentiation of troponin in cardiac and skeletal muscles in chicken embryos as studied by immunofluorescence microscopy
    • Toyota, N., & Shimada, Y. Differentiation of troponin in cardiac and skeletal muscles in chicken embryos as studied by immunofluorescence microscopy. J Cell Biol. 91, 497-504 (1981).
    • (1981) J Cell Biol , vol.91 , pp. 497-504
    • Toyota, N.1    Shimada, Y.2
  • 17
    • 0025119312 scopus 로고
    • Cardiac troponin T in developing, regenerating and denervated rat skeletal muscle
    • Saggin, L., Gorza, L., Ausoni, S., & Schiaffino, S. Cardiac troponin T in developing, regenerating and denervated rat skeletal muscle. Development. 110, 547-554 (1990).
    • (1990) Development , vol.110 , pp. 547-554
    • Saggin, L.1    Gorza, L.2    Ausoni, S.3    Schiaffino, S.4
  • 18
    • 84871733274 scopus 로고    scopus 로고
    • Endogenous cardiac troponin T modulates Ca(2+)-mediated smooth muscle contraction
    • Kajioka, S. et al. Endogenous cardiac troponin T modulates Ca(2+)-mediated smooth muscle contraction. Sci Rep. 2, 979, doi:10.1038/srep00979 (2012).
    • Sci Rep , vol.2 , pp. 979
    • Kajioka, S.1
  • 19
    • 0032958598 scopus 로고    scopus 로고
    • Myosin light chain 2a and 2v identifies the embryonic outflow tract myocardium in the developing rodent heart
    • Franco, D. et al. Myosin light chain 2a and 2v identifies the embryonic outflow tract myocardium in the developing rodent heart. Anat Rec. 254, 135-146, doi:10.1002/(SICI)1097-0185(19990101)254:1<135::AID-AR17>3.0.CO;2-S [pii] (1999).
    • (1999) Anat Rec , vol.254 , pp. 135-146
    • Franco, D.1
  • 20
    • 0032052025 scopus 로고    scopus 로고
    • Patterns of expression in the developing myocardium: Towards a morphologically integrated transcriptional model
    • Franco, D., Lamers, W. H., & Moorman, A. F. Patterns of expression in the developing myocardium: towards a morphologically integrated transcriptional model. Cardiovasc Res. 38, 25-53, doi:S0008-6363(97)00321-0 [pii] (1998).
    • (1998) Cardiovasc Res , vol.38 , pp. 25-53
    • Franco, D.1    Lamers, W.H.2    Moorman, A.F.3
  • 21
    • 84886889331 scopus 로고    scopus 로고
    • Transcriptome-guided functional analyses reveal novel biological properties and regulatory hierarchy of human embryonic stem cell-derived ventricular cardiomyocytes crucial for maturation
    • Poon, E. et al. Transcriptome-guided functional analyses reveal novel biological properties and regulatory hierarchy of human embryonic stem cell-derived ventricular cardiomyocytes crucial for maturation. PLoS One. 8, e77784, doi:10.1371/journal.pone.0077784 PONE-D-13-28733 [pii] (2013).
    • (2013) PLoS One , vol.8 , pp. e77784
    • Poon, E.1
  • 22
    • 67650022307 scopus 로고    scopus 로고
    • Absence of transverse tubules contributes to non-uniform Ca(2+) wavefronts in mouse and human embryonic stem cell-derived cardiomyocytes
    • Lieu, D. K. et al. Absence of transverse tubules contributes to non-uniform Ca(2+) wavefronts in mouse and human embryonic stem cell-derived cardiomyocytes. Stem Cells Dev. 18, 1493-1500, doi:10.1089/scd.2009.0052 (2009).
    • (2009) Stem Cells Dev , vol.18 , pp. 1493-1500
    • Lieu, D.K.1
  • 23
    • 55649098531 scopus 로고    scopus 로고
    • Transcriptional and functional profiling of human embryonic stem cell-derived cardiomyocytes
    • Cao, F. et al. Transcriptional and functional profiling of human embryonic stem cell-derived cardiomyocytes. PLoS One. 3, e3474, doi:10.1371/journal.pone.0003474 (2008).
    • (2008) PLoS One , vol.3 , pp. e3474
    • Cao, F.1
  • 24
    • 54249111025 scopus 로고    scopus 로고
    • Calcium handling in human embryonic stem cell-derived cardiomyocytes
    • Satin, J. et al. Calcium handling in human embryonic stem cell-derived cardiomyocytes. Stem Cells. 26, 1961-1972, doi:10.1634/stemcells.2007-0591 2007-0591 [pii] (2008).
    • (2008) Stem Cells , vol.26 , pp. 1961-1972
    • Satin, J.1
  • 25
    • 79953655401 scopus 로고    scopus 로고
    • Calcium handling in human induced pluripotent stem cell derived cardiomyocytes
    • Itzhaki, I. et al. Calcium handling in human induced pluripotent stem cell derived cardiomyocytes. PLoS One. 6, e18037, doi:10.1371/journal.pone.0018037 (2011).
    • (2011) PLoS One , vol.6 , pp. e18037
    • Itzhaki, I.1
  • 26
    • 0028792186 scopus 로고
    • Cardiac troponin-I is not expressed in fetal and healthy or diseased adult human skeletal muscle tissue
    • Bodor, G. S., Porterfield, D., Voss, E. M., Smith, S., & Apple, F. S. Cardiac troponin-I is not expressed in fetal and healthy or diseased adult human skeletal muscle tissue. Clin Chem. 41, 1710-1715 (1995).
    • (1995) Clin Chem , vol.41 , pp. 1710-1715
    • Bodor, G.S.1    Porterfield, D.2    Voss, E.M.3    Smith, S.4    Apple, F.S.5
  • 27
    • 0025935299 scopus 로고
    • Troponin I isoform expression in human heart
    • Hunkeler, N. M., Kullman, J., & Murphy, A. M. Troponin I isoform expression in human heart. Circ Res. 69, 1409-1414 (1991).
    • (1991) Circ Res , vol.69 , pp. 1409-1414
    • Hunkeler, N.M.1    Kullman, J.2    Murphy, A.M.3
  • 28
    • 0026008911 scopus 로고
    • Developmental expression of troponin I isoforms in fetal human heart
    • Bhavsar, P. K. et al. Developmental expression of troponin I isoforms in fetal human heart. FEBS Lett. 292, 5-8, doi:0014-5793(91)80820-S [pii] (1991).
    • (1991) FEBS Lett , vol.292 , pp. 5-8
    • Bhavsar, P.K.1
  • 29
    • 0034663350 scopus 로고    scopus 로고
    • Patterning the embryonic heart: Identification of five mouse Iroquois homeobox genes in the developing heart
    • Christoffels, V. M., Keijser, A. G., Houweling, A. C., Clout, D. E., & Moorman, A. F. Patterning the embryonic heart: identification of five mouse Iroquois homeobox genes in the developing heart. Dev Biol. 224, 263-274, doi:10.1006/dbio.2000.9801 S0012-1606(00)99801-4 [pii] (2000).
    • (2000) Dev Biol , vol.224 , pp. 263-274
    • Christoffels, V.M.1    Keijser, A.G.2    Houweling, A.C.3    Clout, D.E.4    Moorman, A.F.5
  • 30
    • 0034650311 scopus 로고    scopus 로고
    • Cardiac expression of the ventricle-specific homeobox gene Irx4 is modulated by Nkx2-5 and dHand
    • Bruneau, B. G. et al. Cardiac expression of the ventricle-specific homeobox gene Irx4 is modulated by Nkx2-5 and dHand. Dev Biol. 217, 266-277, doi:10.1006/dbio.1999.9548 S0012-1606(99)99548-9 [pii] (2000).
    • (2000) Dev Biol , vol.217 , pp. 266-277
    • Bruneau, B.G.1
  • 31
    • 0033582685 scopus 로고    scopus 로고
    • Regulation of chamber-specific gene expression in the developing heart by Irx4
    • Bao, Z. Z., Bruneau, B. G., Seidman, J. G., Seidman, C. E., & Cepko, C. L. Regulation of chamber-specific gene expression in the developing heart by Irx4. Science. 283, 1161-1164 (1999).
    • (1999) Science , vol.283 , pp. 1161-1164
    • Bao, Z.Z.1    Bruneau, B.G.2    Seidman, J.G.3    Seidman, C.E.4    Cepko, C.L.5
  • 32
    • 84894243644 scopus 로고    scopus 로고
    • Irx4 identifies a chamber-specific cell population that contributes to ventricular myocardium development
    • Nelson, D. O., Jin, D., Downs, K., Kamp, T. J., & Lyons, G. E. Irx4 identifies a chamber-specific cell population that contributes to ventricular myocardium development. Dev Dyn. 243, 381-392, doi:10.1002/dvdy.24078 (2013).
    • (2013) Dev Dyn , vol.243 , pp. 381-392
    • Nelson, D.O.1    Jin, D.2    Downs, K.3    Kamp, T.J.4    Lyons, G.E.5
  • 33
    • 0019431847 scopus 로고
    • Kinetic evidence for a precursor pool of troponin-I
    • Turnover of cardiac troponin subunits
    • Martin, A. F. Turnover of cardiac troponin subunits. Kinetic evidence for a precursor pool of troponin-I. J Biol Chem. 256, 964-968 (1981).
    • (1981) J Biol Chem , vol.256 , pp. 964-968
    • Martin, A.F.1
  • 34
    • 84880227000 scopus 로고    scopus 로고
    • Structural and functional maturation of cardiomyocytes derived from human pluripotent stem cells
    • Lundy, S. D., Zhu, W. Z., Regnier, M., & Laflamme, M. A. Structural and functional maturation of cardiomyocytes derived from human pluripotent stem cells. Stem Cells Dev. 22, 1991-2002, doi:10.1089/scd.2012.0490 (2013).
    • (2013) Stem Cells Dev , vol.22 , pp. 1991-2002
    • Lundy, S.D.1    Zhu, W.Z.2    Regnier, M.3    Laflamme, M.A.4
  • 35
    • 3142647682 scopus 로고    scopus 로고
    • Nomenclature of the proteins of cows" milk--sixth revision
    • Farrell, H. M., Jr.et al. Nomenclature of the proteins of cows" milk--sixth revision. Journal of dairy science. 87, 1641-1674, doi:10.3168/jds.S0022-0302(04)73319-6 (2004).
    • Journal of dairy science , vol.87 , pp. 1641-1674
    • Farrell, H.M.1
  • 36
    • 0017575491 scopus 로고
    • Biological properties of goat immunoglobulins G
    • Micusan, V. V., & Borduas, A. G. Biological properties of goat immunoglobulins G. Immunology. 32, 373-381 (1977).
    • (1977) Immunology , vol.32 , pp. 373-381
    • Micusan, V.V.1    Borduas, A.G.2
  • 37
    • 0028280625 scopus 로고
    • In situ analysis of the cardiac muscle gene program during embryogenesis
    • Lyons, G. E. In situ analysis of the cardiac muscle gene program during embryogenesis. Trends Cardiovasc Med. 4, 70-77, doi:10.1016/1050-1738(94)90012-4 1050-1738(94)90012-4 [pii] (1994).
    • (1994) Trends Cardiovasc Med , vol.4 , pp. 70-77
    • Lyons, G.E.1
  • 38
    • 0032715827 scopus 로고    scopus 로고
    • HRT1, HRT2, and HRT3: A new subclass of bHLH transcription factors marking specific cardiac, somitic, and pharyngeal arch segments
    • Nakagawa, O., Nakagawa, M., Richardson, J. A., Olson, E. N., & Srivastava, D. HRT1, HRT2, and HRT3: a new subclass of bHLH transcription factors marking specific cardiac, somitic, and pharyngeal arch segments. Dev Biol. 216, 72-84, doi:10.1006/dbio.1999.9454 S0012-1606(99)99454-X [pii] (1999).
    • (1999) Dev Biol , vol.216 , pp. 72-84
    • Nakagawa, O.1    Nakagawa, M.2    Richardson, J.A.3    Olson, E.N.4    Srivastava, D.5
  • 39
    • 34249932672 scopus 로고    scopus 로고
    • Essential roles of the bHLH transcription factor Hrt2 in repression of atrial gene expression and maintenance of postnatal cardiac function
    • Xin, M. et al. Essential roles of the bHLH transcription factor Hrt2 in repression of atrial gene expression and maintenance of postnatal cardiac function. Proc Natl Acad Sci U S A. 104, 7975-7980, doi:0702447104 [pii] 10.1073/pnas.0702447104 (2007).
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 7975-7980
    • Xin, M.1
  • 41
    • 0038237303 scopus 로고    scopus 로고
    • Atrial chamber-specific expression of sarcolipin is regulated during development and hypertrophic remodeling
    • Minamisawa, S. et al. Atrial chamber-specific expression of sarcolipin is regulated during development and hypertrophic remodeling. J Biol Chem. 278, 9570-9575 (2003).
    • (2003) J Biol Chem , vol.278 , pp. 9570-9575
    • Minamisawa, S.1
  • 42
    • 0025298331 scopus 로고
    • Atrial natriuretic factor in the heart of the human embryo
    • Larsen, T. H. Atrial natriuretic factor in the heart of the human embryo. Acta Anat (Basel). 138, 132-136 (1990).
    • (1990) Acta Anat (Basel) , vol.138 , pp. 132-136
    • Larsen, T.H.1
  • 43
    • 0023696087 scopus 로고
    • Atrial-natriuretic-factor mRNA is developmentally regulated in heart ventricles and actively expressed in cultured ventricular cardiac muscle cells of rat and human
    • Claycomb, W. C. Atrial-natriuretic-factor mRNA is developmentally regulated in heart ventricles and actively expressed in cultured ventricular cardiac muscle cells of rat and human. Biochem J. 255, 617-620 (1988).
    • (1988) Biochem J , vol.255 , pp. 617-620
    • Claycomb, W.C.1
  • 44
    • 0034852125 scopus 로고    scopus 로고
    • Divergent expression of delayed rectifier K(+) channel subunits during mouse heart development
    • Franco, D. et al. Divergent expression of delayed rectifier K(+) channel subunits during mouse heart development. Cardiovasc Res. 52, 65-75, doi:S0008636301003492 [pii] (2001).
    • (2001) Cardiovasc Res , vol.52 , pp. 65-75
    • Franco, D.1
  • 45
    • 2442513900 scopus 로고    scopus 로고
    • The transcriptional repressor Tbx3 delineates the developing central conduction system of the heart
    • Hoogaars, W. M. et al. The transcriptional repressor Tbx3 delineates the developing central conduction system of the heart. Cardiovasc Res. 62, 489-499, doi:10.1016/j.cardiores.2004.01.030 S0008636304000689 [pii] (2004).
    • (2004) Cardiovasc Res , vol.62 , pp. 489-499
    • Hoogaars, W.M.1
  • 46
    • 0029018708 scopus 로고
    • Identification of a new family of tissue-specific basic helix-loop-helix proteins with a two-hybrid system
    • Hollenberg, S. M., Sternglanz, R., Cheng, P. F., & Weintraub, H. Identification of a new family of tissue-specific basic helix-loop-helix proteins with a two-hybrid system. Mol Cell Biol. 15, 3813-3822 (1995).
    • (1995) Mol Cell Biol , vol.15 , pp. 3813-3822
    • Hollenberg, S.M.1    Sternglanz, R.2    Cheng, P.F.3    Weintraub, H.4
  • 47
    • 0029549692 scopus 로고
    • A subclass of bHLH proteins required for cardiac morphogenesis
    • Srivastava, D., Cserjesi, P., & Olson, E. N. A subclass of bHLH proteins required for cardiac morphogenesis. Science. 270, 1995-1999 (1995).
    • (1995) Science , vol.270 , pp. 1995-1999
    • Srivastava, D.1    Cserjesi, P.2    Olson, E.N.3
  • 48
    • 0031882143 scopus 로고    scopus 로고
    • Heart and extra-embryonic mesodermal defects in mouse embryos lacking the bHLH transcription factor Hand1
    • Firulli, A. B., McFadden, D. G., Lin, Q., Srivastava, D., & Olson, E. N. Heart and extra-embryonic mesodermal defects in mouse embryos lacking the bHLH transcription factor Hand1. Nat Genet. 18, 266-270, doi:10.1038/ng0398-266 (1998).
    • (1998) Nat Genet , vol.18 , pp. 266-270
    • Firulli, A.B.1    McFadden, D.G.2    Lin, Q.3    Srivastava, D.4    Olson, E.N.5
  • 49
    • 84891913381 scopus 로고    scopus 로고
    • Differences in the expression pattern of HCN isoforms among mammalian tissues: Sources and implications
    • Calejo, A. I. et al. Differences in the expression pattern of HCN isoforms among mammalian tissues: sources and implications. Mol Biol Rep. 41, 297-307, doi:10.1007/s11033-013-2862-2 (2013).
    • (2013) Mol Biol Rep , vol.41 , pp. 297-307
    • Calejo, A.I.1
  • 50
    • 84881639050 scopus 로고    scopus 로고
    • HCN4 charges up the first heart field
    • Stevens, S. M., & Pu, W. T. HCN4 charges up the first heart field. Circ Res. 113, 350-351, doi:10.1161/CIRCRESAHA.113.301981 CIRCRESAHA.113.301981 [pii] (2013).
    • (2013) Circ Res , vol.113 , pp. 350-351
    • Stevens, S.M.1    Pu, W.T.2
  • 51
    • 84883740296 scopus 로고    scopus 로고
    • A HCN4+ cardiomyogenic progenitor derived from the first heart field and human pluripotent stem cells
    • Spater, D. et al. A HCN4+ cardiomyogenic progenitor derived from the first heart field and human pluripotent stem cells. Nat Cell Biol. 15, 1098-1106, doi:10.1038/ncb2824 ncb2824 [pii] (2013).
    • (2013) Nat Cell Biol , vol.15 , pp. 1098-1106
    • Spater, D.1
  • 52
    • 80052030185 scopus 로고    scopus 로고
    • Pluripotent stem cell models of cardiac disease and their implication for drug discovery and development
    • Davis, R. P., van den Berg, C. W., Casini, S., Braam, S. R., & Mummery, C. L. Pluripotent stem cell models of cardiac disease and their implication for drug discovery and development. Trends Mol Med. 17, 475-484, doi:S1471-4914(11)00078-5 [pii] 10.1016/j.molmed.2011.05.001 (2011).
    • Trends Mol Med , vol.17 , pp. 475-484
    • Davis, R.P.1    Van Den Berg, C.W.2    Casini, S.3    Braam, S.R.4    Mummery, C.L.5
  • 53
    • 0038210217 scopus 로고    scopus 로고
    • Differentiation of human embryonic stem cells to cardiomyocytes: Role of coculture with visceral endoderm-like cells
    • Mummery, C. et al. Differentiation of human embryonic stem cells to cardiomyocytes: role of coculture with visceral endoderm-like cells. Circulation. 107, 2733-2740, doi:10.1161/01.CIR.0000068356.38592.68 01.CIR.0000068356.38592.68 [pii] (2003).
    • (2003) Circulation , vol.107 , pp. 2733-2740
    • Mummery, C.1
  • 54
    • 80055108726 scopus 로고    scopus 로고
    • Purification of specific cell population by fluorescence activated cell sorting (FACS)
    • Basu, S., Campbell, H. M., Dittel, B. N., & Ray, A. Purification of specific cell population by fluorescence activated cell sorting (FACS). J Vis Exp. (41), doi:10.3791/1546 1546 [pii] (2010).
    • (2010) J Vis Exp , Issue.41
    • Basu, S.1    Campbell, H.M.2    Dittel, B.N.3    Ray, A.4
  • 55
    • 80755142726 scopus 로고    scopus 로고
    • SIRPA is a specific cell-surface marker for isolating cardiomyocytes derived from human pluripotent stem cells
    • Dubois, N. C. et al. SIRPA is a specific cell-surface marker for isolating cardiomyocytes derived from human pluripotent stem cells. Nat Biotechnol. 29, 1011-1018, doi:10.1038/nbt.2005 nbt.2005 [pii] (2011).
    • (2011) Nat Biotechnol , vol.29 , pp. 1011-1018
    • Dubois, N.C.1
  • 56
    • 84865568498 scopus 로고    scopus 로고
    • OMICS-based exploration of the molecular phenotype of resident cardiac progenitor cells from adult murine heart
    • Samal, R. et al. OMICS-based exploration of the molecular phenotype of resident cardiac progenitor cells from adult murine heart. J Proteomics. 75, 5304-5315, doi:10.1016/j.jprot.2012.06.010 S1874-3919(12)00435-6 [pii] (2012).
    • (2012) J Proteomics , vol.75 , pp. 5304-5315
    • Samal, R.1
  • 57
    • 77949862634 scopus 로고    scopus 로고
    • Identification of cell surface proteins for antibody-based selection of human embryonic stem cell-derived cardiomyocytes
    • Van Hoof, D. et al. Identification of cell surface proteins for antibody-based selection of human embryonic stem cell-derived cardiomyocytes. J Proteome Res. 9, 1610-1618, doi:10.1021/pr901138a (2010).
    • (2010) J Proteome Res , vol.9 , pp. 1610-1618
    • Van Hoof, D.1
  • 58
    • 46749104456 scopus 로고    scopus 로고
    • A novel role for proteomics in the discovery of cell-surface markers on stem cells: Scratching the surface
    • Gundry, R. L., Boheler, K. R., Van Eyk, J. E., & Wollscheid, B. A novel role for proteomics in the discovery of cell-surface markers on stem cells: Scratching the surface. Proteomics Clin Appl. 2, 892-903, doi:10.1002/prca.200780122 (2008).
    • (2008) Proteomics Clin Appl , vol.2 , pp. 892-903
    • Gundry, R.L.1    Boheler, K.R.2    Van Eyk, J.E.3    Wollscheid, B.4
  • 60
    • 84864821878 scopus 로고    scopus 로고
    • A Cell Surfaceome Map for Immunophenotyping and Sorting Pluripotent Stem Cells
    • Gundry, R. L. et al. A Cell Surfaceome Map for Immunophenotyping and Sorting Pluripotent Stem Cells. Mol Cell Proteomics. 11, 303-316, doi:M112.018135 [pii] 10.1074/mcp.M112.018135 (2012).
    • (2012) Mol Cell Proteomics , vol.11 , pp. 303-316
    • Gundry, R.L.1
  • 61
    • 33746617272 scopus 로고    scopus 로고
    • Hematopoietic stem cells: The paradigmatic tissue-specific stem cell
    • Bryder, D., Rossi, D. J., & Weissman, I. L. Hematopoietic stem cells: the paradigmatic tissue-specific stem cell. Am J Pathol. 169, 338-346, doi:169/2/338 [pii] (2006).
    • (2006) Am J Pathol , vol.169 , pp. 338-346
    • Bryder, D.1    Rossi, D.J.2    Weissman, I.L.3
  • 62
    • 0038406789 scopus 로고    scopus 로고
    • Biology of hematopoietic stem cells and progenitors: Implications for clinical application
    • Kondo, M. et al. Biology of hematopoietic stem cells and progenitors: implications for clinical application. Annu Rev Immunol. 21, 759-806 (2003).
    • (2003) Annu Rev Immunol , vol.21 , pp. 759-806
    • Kondo, M.1
  • 63
    • 14544274561 scopus 로고    scopus 로고
    • Hematopoietic stem and progenitor cells: Clinical and preclinical regeneration of the hematolymphoid system
    • Shizuru, J. A., Negrin, R. S., & Weissman, I. L. Hematopoietic stem and progenitor cells: clinical and preclinical regeneration of the hematolymphoid system. Annu Rev Med. 56, 509-538, doi:10.1146/annurev.med.54.101601.152334 (2005).
    • (2005) Annu Rev Med , vol.56 , pp. 509-538
    • Shizuru, J.A.1    Negrin, R.S.2    Weissman, I.L.3
  • 64
    • 55749107812 scopus 로고    scopus 로고
    • The origins of the identification and isolation of hematopoietic stem cells, and their capability to induce donor-specific transplantation tolerance and treat autoimmune diseases
    • Weissman, I. L., & Shizuru, J. A. The origins of the identification and isolation of hematopoietic stem cells, and their capability to induce donor-specific transplantation tolerance and treat autoimmune diseases. Blood. 112, 3543-3553 (2008).
    • (2008) Blood , vol.112 , pp. 3543-3553
    • Weissman, I.L.1    Shizuru, J.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.