메뉴 건너뛰기




Volumn 96, Issue 5, 2014, Pages 779-784

A river runs through it: How autophagy, senescence, and phagocytosis could be linked to phospholipase D by Wnt signaling

Author keywords

Cancer; Catabolic metabolism; Cell survival; Inflammation; mTOR; Organogenesis

Indexed keywords

BETA CATENIN; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHOLIPASE D; PHOSPHOLIPID; WNT PROTEIN;

EID: 84908290096     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.2VMR0214-120RR     Document Type: Review
Times cited : (18)

References (49)
  • 1
    • 84874218279 scopus 로고    scopus 로고
    • Neutrophils and macrophages: The main partners of phagocyte cell systems
    • Silva, M. T., Correia-Neves, M. (2012) Neutrophils and macrophages: the main partners of phagocyte cell systems. Front. Immunol. 3, 174.
    • (2012) Front. Immunol , vol.3 , pp. 174
    • Silva, M.T.1    Correia-Neves, M.2
  • 2
    • 84880376355 scopus 로고    scopus 로고
    • Emerging regulation and functions of autophagy
    • Boya, P., Reggiori, F., Codogno, P. (2013) Emerging regulation and functions of autophagy. Nat. Cell Biol. 15, 713–720.
    • (2013) Nat. Cell Biol , vol.15 , pp. 713-720
    • Boya, P.1    Reggiori, F.2    Codogno, P.3
  • 4
    • 78649704325 scopus 로고    scopus 로고
    • Autophagy and metabolism
    • Rabinowitz, J. D., White, E. (2010) Autophagy and metabolism. Science 330, 1344–1348.
    • (2010) Science , vol.330 , pp. 1344-1348
    • Rabinowitz, J.D.1    White, E.2
  • 6
    • 77956402268 scopus 로고    scopus 로고
    • Targeting autophagy to fight hematopoietic malignancies
    • Puissant, A., Robert, G., Auberger, P. (2010) Targeting autophagy to fight hematopoietic malignancies. Cell Cycle 9, 3470–3478.
    • (2010) Cell Cycle , vol.9 , pp. 3470-3478
    • Puissant, A.1    Robert, G.2    Auberger, P.3
  • 7
    • 84893414176 scopus 로고    scopus 로고
    • Phosphatidic acid, phospholipase D and tumorigenesis
    • Gomez-Cambronero, J. (2013) Phosphatidic acid, phospholipase D and tumorigenesis. Adv. Biol Regul. 54, 197–206.
    • (2013) Adv. Biol Regul , vol.54 , pp. 197-206
    • Gomez-Cambronero, J.1
  • 8
    • 80053284579 scopus 로고    scopus 로고
    • The exquisite regulation of PLD2 by a wealth of interacting proteins: S6K, Grb2, Sos, WASp and Rac2 (and a surprise discovery: PLD2 is a GEF)
    • Gomez-Cambronero, J. (2011) The exquisite regulation of PLD2 by a wealth of interacting proteins: S6K, Grb2, Sos, WASp and Rac2 (and a surprise discovery: PLD2 is a GEF). Cell. Signal. 23, 1885–1895.
    • (2011) Cell. Signal , vol.23 , pp. 1885-1895
    • Gomez-Cambronero, J.1
  • 9
    • 77955900058 scopus 로고    scopus 로고
    • New concepts in phospholipase D signaling in inflammation and cancer
    • Gomez-Cambronero, J. (2010) New concepts in phospholipase D signaling in inflammation and cancer. Sci. World J. 10, 1356–1369.
    • (2010) Sci. World J , vol.10 , pp. 1356-1369
    • Gomez-Cambronero, J.1
  • 10
    • 83255192189 scopus 로고    scopus 로고
    • A novel phospholipase D2-Grb2- WASp heterotrimer regulates leukocyte phagocytosis in a two-step mechanism
    • Kantonen, S., Hatton, N., Mahankali, M., Henkels, K. M., Park, H., Cox, D., Gomez-Cambronero, J. (2011) A novel phospholipase D2-Grb2- WASp heterotrimer regulates leukocyte phagocytosis in a two-step mechanism. Mol. Cell. Biol. 31, 4524–4537.
    • (2011) Mol. Cell. Biol , vol.31 , pp. 4524-4537
    • Kantonen, S.1    Hatton, N.2    Mahankali, M.3    Henkels, K.M.4    Park, H.5    Cox, D.6    Gomez-Cambronero, J.7
  • 11
    • 79955871451 scopus 로고    scopus 로고
    • The mechanism of cell membrane ruffling relies on a phospholipase D2 (PLD2), Grb2 and Rac2 association
    • Mahankali, M., Peng, H. J., Cox, D., Gomez-Cambronero, J. (2011) The mechanism of cell membrane ruffling relies on a phospholipase D2 (PLD2), Grb2 and Rac2 association. Cell. Signal. 23, 1291–1298.
    • (2011) Cell. Signal , vol.23 , pp. 1291-1298
    • Mahankali, M.1    Peng, H.J.2    Cox, D.3    Gomez-Cambronero, J.4
  • 12
    • 79955480000 scopus 로고    scopus 로고
    • Cell invasion of highly metastatic MTLn3 cancer cells is dependent on phospholipase D2 (PLD2) and Janus kinase 3 (JAK3)
    • Henkels, K. M., Farkaly, T., Mahankali, M., Segall, J. E., Gomez-Cambronero, J. (2011) Cell invasion of highly metastatic MTLn3 cancer cells is dependent on phospholipase D2 (PLD2) and Janus kinase 3 (JAK3). J. Mol. Biol. 408, 850–862.
    • (2011) J. Mol. Biol , vol.408 , pp. 850-862
    • Henkels, K.M.1    Farkaly, T.2    Mahankali, M.3    Segall, J.E.4    Gomez-Cambronero, J.5
  • 13
    • 77956695757 scopus 로고    scopus 로고
    • The molecular basis of phospholipase D2-induced chemotaxis: Elucidation of differential pathways in macrophages and fibroblasts
    • Knapek, K., Frondorf, K., Post, J., Short, S., Cox, D., Gomez-Cambronero, J. (2010) The molecular basis of phospholipase D2-induced chemotaxis: elucidation of differential pathways in macrophages and fibroblasts. Mol. Cell. Biol. 30, 4492–4506.
    • (2010) Mol. Cell. Biol , vol.30 , pp. 4492-4506
    • Knapek, K.1    Frondorf, K.2    Post, J.3    Short, S.4    Cox, D.5    Gomez-Cambronero, J.6
  • 15
    • 84867607902 scopus 로고    scopus 로고
    • Increased cell growth due to a new lipase-GEF (phospholipase D2) fastly acting on Ras
    • Henkels, K. M., Mahankali, M., Gomez-Cambronero, J. (2013) Increased cell growth due to a new lipase-GEF (phospholipase D2) fastly acting on Ras. Cell. Signal. 25, 198–205.
    • (2013) Cell. Signal , vol.25 , pp. 198-205
    • Henkels, K.M.1    Mahankali, M.2    Gomez-Cambronero, J.3
  • 16
    • 79955808267 scopus 로고    scopus 로고
    • Phospholipase D2 induces stress fiber formation through mediating nucleotide exchange for RhoA
    • Jeon, H., Kwak, D., Noh, J., Lee, M. N., Lee, C. S., Suh, P. G., Ryu, S. H. (2011) Phospholipase D2 induces stress fiber formation through mediating nucleotide exchange for RhoA. Cell. Signal. 23, 1320–1326.
    • (2011) Cell. Signal , vol.23 , pp. 1320-1326
    • Jeon, H.1    Kwak, D.2    Noh, J.3    Lee, M.N.4    Lee, C.S.5    Suh, P.G.6    Ryu, S.H.7
  • 17
    • 77953504198 scopus 로고    scopus 로고
    • Mammalian target of rapamycin (mTOR) and S6 kinase downregulate phospholipase D2 basal expression and function
    • Tabatabaian, F., Dougherty, K., Di Fulvio, M., Gomez-Cambronero, J. (2010) Mammalian target of rapamycin (mTOR) and S6 kinase downregulate phospholipase D2 basal expression and function. J. Biol. Chem. 285, 18991–19001.
    • (2010) J. Biol. Chem , vol.285 , pp. 18991-19001
    • Tabatabaian, F.1    Dougherty, K.2    Di Fulvio, M.3    Gomez-Cambronero, J.4
  • 18
    • 79551598347 scopus 로고    scopus 로고
    • AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
    • Kim, J., Kundu, M., Viollet, B., Guan, K. L. (2011) AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1. Nat. Cell Biol. 13, 132–141.
    • (2011) Nat.Cell Biol , vol.13 , pp. 132-141
    • Kim, J.1    Kundu, M.2    Viollet, B.3    Guan, K.L.4
  • 19
    • 84887013009 scopus 로고    scopus 로고
    • Macrophage migration arrest due to a winning balance of Rac2/Sp1 repression over β-catenin-induced PLD expression
    • Speranza, F. J., Mahankali, M., Gomez-Cambronero, J. (2013) Macrophage migration arrest due to a winning balance of Rac2/Sp1 repression over β-catenin-induced PLD expression. J. Leukoc. Biol. 94, 953–962.
    • (2013) J. Leukoc. Biol , vol.94 , pp. 953-962
    • Speranza, F.J.1    Mahankali, M.2    Gomez-Cambronero, J.3
  • 20
    • 84860372433 scopus 로고    scopus 로고
    • Induction of autophagy by palmitic acid via protein kinase C-mediated signaling pathway independent of mTOR (mammalian target of rapamycin)
    • Tan, S. H., Shui, G., Zhou, J., Li, J. J., Bay, B. H., Wenk, M. R., Shen, H. M. (2012) Induction of autophagy by palmitic acid via protein kinase C-mediated signaling pathway independent of mTOR (mammalian target of rapamycin). J. Biol. Chem. 287, 14364–14376.
    • (2012) J. Biol. Chem , vol.287 , pp. 14364-14376
    • Tan, S.H.1    Shui, G.2    Zhou, J.3    Li, J.J.4    Bay, B.H.5    Wenk, M.R.6    Shen, H.M.7
  • 21
    • 68949164754 scopus 로고    scopus 로고
    • Phospholipase D in endocytosis and endosomal recycling pathways
    • Donaldson, J. G. (2009) Phospholipase D in endocytosis and endosomal recycling pathways. Biochim. Biophys. Acta 1791, 845–849.
    • (2009) Biochim. Biophys. Acta , vol.1791 , pp. 845-849
    • Donaldson, J.G.1
  • 23
    • 0036854458 scopus 로고    scopus 로고
    • Phospholipase D2 is localized to the rims of the Golgi apparatus in mammalian cells
    • Freyberg, Z., Bourgoin, S., Shields, D. (2002) Phospholipase D2 is localized to the rims of the Golgi apparatus in mammalian cells. Mol. Biol. Cell 13, 3930–3942.
    • (2002) Mol. Biol. Cell , vol.13 , pp. 3930-3942
    • Freyberg, Z.1    Bourgoin, S.2    Shields, D.3
  • 24
    • 84934441448 scopus 로고    scopus 로고
    • Autophagosome and phagosome
    • Deretic, V. (2008) Autophagosome and phagosome. Methods Mol. Biol. 445, 1–10.
    • (2008) Methods Mol. Biol , vol.445 , pp. 1-10
    • Deretic, V.1
  • 25
    • 84859965801 scopus 로고    scopus 로고
    • Arf6 promotes autophagosome formation via effects on phosphatidylinositol 4,5- bisphosphate and phospholipase D
    • Moreau, K., Ravikumar, B., Puri, C., Rubinsztein, D. C. (2012) Arf6 promotes autophagosome formation via effects on phosphatidylinositol 4,5- bisphosphate and phospholipase D. J. Cell Biol. 196, 483–496.
    • (2012) J. Cell Biol , vol.196 , pp. 483-496
    • Moreau, K.1    Ravikumar, B.2    Puri, C.3    Rubinsztein, D.C.4
  • 27
    • 79955061238 scopus 로고    scopus 로고
    • Diacylglycerol kinase inhibitor R59022-induced autophagy and apoptosis in the neuronal cell line NG108-15
    • Takita, T., Konuma, T., Hanazato, M., Inoue, H. (2011) Diacylglycerol kinase inhibitor R59022-induced autophagy and apoptosis in the neuronal cell line NG108-15. Arch. Biochem. Biophys. 509, 197–201.
    • (2011) Arch. Biochem. Biophys , vol.509 , pp. 197-201
    • Takita, T.1    Konuma, T.2    Hanazato, M.3    Inoue, H.4
  • 30
    • 77950680067 scopus 로고    scopus 로고
    • A comprehensive model that explains the regulation of phospholipase D2 activity by phosphorylation-dephosphorylation
    • Henkels, K. M., Peng, H. J., Frondorf, K., Gomez-Cambronero, J. (2010) A comprehensive model that explains the regulation of phospholipase D2 activity by phosphorylation-dephosphorylation. Mol. Cell. Biol. 30, 2251–2263.
    • (2010) Mol. Cell. Biol , vol.30 , pp. 2251-2263
    • Henkels, K.M.1    Peng, H.J.2    Frondorf, K.3    Gomez-Cambronero, J.4
  • 31
  • 32
    • 0036200219 scopus 로고    scopus 로고
    • Proliferating or differentiating stimuli act on different lipid-dependent signaling pathways in nuclei of human leukemia cells
    • Neri, L. M., Bortul, R., Borgatti, P., Tabellini, G., Baldini, G., Capitani, S., Martelli, A. M. (2002) Proliferating or differentiating stimuli act on different lipid-dependent signaling pathways in nuclei of human leukemia cells. Mol. Biol. Cell 13, 947–964.
    • (2002) Mol. Biol. Cell , vol.13 , pp. 947-964
    • Neri, L.M.1    Bortul, R.2    Borgatti, P.3    Tabellini, G.4    Baldini, G.5    Capitani, S.6    Martelli, A.M.7
  • 34
    • 70350418625 scopus 로고    scopus 로고
    • MTOR signaling at a glance
    • Laplante, M., Sabatini, D. M. (2009) mTOR signaling at a glance. J. Cell Sci. 122, 3589–3594.
    • (2009) J. Cell Sci , vol.122 , pp. 3589-3594
    • Laplante, M.1    Sabatini, D.M.2
  • 35
    • 33845352555 scopus 로고    scopus 로고
    • Wnt signalling and the actin cytoskeleton
    • Akiyama, T., Kawasaki, Y. (2006) Wnt signalling and the actin cytoskeleton. Oncogene 25, 7538–7544.
    • (2006) Oncogene , vol.25 , pp. 7538-7544
    • Akiyama, T.1    Kawasaki, Y.2
  • 37
    • 77957881271 scopus 로고    scopus 로고
    • Positive feedback regulation between phospholipase D and Wnt signaling promotes Wnt-driven anchorageindependent growth of colorectal cancer cells
    • Kang, D. W., Min do, S. (2010) Positive feedback regulation between phospholipase D and Wnt signaling promotes Wnt-driven anchorageindependent growth of colorectal cancer cells. PLoS One 5, e12109.
    • (2010) PLoS One , vol.5
    • Kang, D.W.1    Min Do, S.2
  • 40
    • 84870896835 scopus 로고    scopus 로고
    • Bacterial autophagy: The trigger, the target and the timing
    • Tattoli, I., Sorbara, M. T., Philpott, D. J., Girardin, S. E. (2012) Bacterial autophagy: the trigger, the target and the timing. Autophagy 8, 1848–1850.
    • (2012) Autophagy , vol.8 , pp. 1848-1850
    • Tattoli, I.1    Sorbara, M.T.2    Philpott, D.J.3    Girardin, S.E.4
  • 41
    • 84887269499 scopus 로고    scopus 로고
    • Feeding uninvited guests: MTOR and AMPK set the table for intracellular pathogens
    • Brunton, J., Steele, S., Ziehr, B., Moorman, N., Kawula, T. (2013) Feeding uninvited guests: mTOR and AMPK set the table for intracellular pathogens. PLoS Pathog. 9, e1003552.
    • (2013) PLoS Pathog , vol.9
    • Brunton, J.1    Steele, S.2    Ziehr, B.3    Moorman, N.4    Kawula, T.5
  • 42
    • 84877610008 scopus 로고    scopus 로고
    • Bacterial subversion of host innate immune pathways
    • Baxt, L. A., Garza-Mayers, A. C., Goldberg, M. B. (2013) Bacterial subversion of host innate immune pathways. Science 340, 697–701.
    • (2013) Science , vol.340 , pp. 697-701
    • Baxt, L.A.1    Garza-Mayers, A.C.2    Goldberg, M.B.3
  • 43
    • 0032813328 scopus 로고    scopus 로고
    • Phospholipase D in cellular senescence
    • Venable, M. E., Obeid, L. M. (1999) Phospholipase D in cellular senescence. Biochim. Biophys. Acta 1439, 291–298.
    • (1999) Biochim. Biophys. Acta , vol.1439 , pp. 291-298
    • Venable, M.E.1    Obeid, L.M.2
  • 44
    • 0030757842 scopus 로고    scopus 로고
    • Changes in the activity and mRNA levels of phospholipase D during ceramide-induced apoptosis in rat C6 glial cells
    • Yoshimura, S., Sakai, H., Ohguchi, K., Nakashima, S., Banno, Y., Nishimura, Y., Sakai, N., Nozawa, Y. (1997) Changes in the activity and mRNA levels of phospholipase D during ceramide-induced apoptosis in rat C6 glial cells. J. Neurochem. 69, 713–720.
    • (1997) J. Neurochem , vol.69 , pp. 713-720
    • Yoshimura, S.1    Sakai, H.2    Ohguchi, K.3    Nakashima, S.4    Banno, Y.5    Nishimura, Y.6    Sakai, N.7    Nozawa, Y.8
  • 45
    • 0037469747 scopus 로고    scopus 로고
    • Antiapoptotic role of phospholipase D isozymes in the glutamate-induced cell death
    • Kim, K. O., Lee, K. H., Kim, Y. H., Park, S. K., Han, J. S. (2003) Antiapoptotic role of phospholipase D isozymes in the glutamate-induced cell death. Exp. Mol. Med. 35, 38–45.
    • (2003) Exp. Mol. Med , vol.35 , pp. 38-45
    • Kim, K.O.1    Lee, K.H.2    Kim, Y.H.3    Park, S.K.4    Han, J.S.5
  • 47
    • 78751480479 scopus 로고    scopus 로고
    • Phospholipase D meets Wnt signaling: A new target for cancer therapy
    • Kang, D. W., Choi, K. Y., Min do, S. (2011) Phospholipase D meets Wnt signaling: a new target for cancer therapy. Cancer Res. 71, 293–297.
    • (2011) Cancer Res , vol.71 , pp. 293-297
    • Kang, D.W.1    Choi, K.Y.2    Min Do, S.3
  • 49
    • 79955479506 scopus 로고    scopus 로고
    • Wnt signaling in macrophages: Augmenting and inhibiting mycobacteria-induced inflammatory responses
    • Schaale, K., Neumann, J., Schneider, D., Ehlers, S., Reiling, N. (2011) Wnt signaling in macrophages: augmenting and inhibiting mycobacteria-induced inflammatory responses. Eur. J. Cell Biol. 90, 553–559.
    • (2011) Eur. J. Cell Biol , vol.90 , pp. 553-559
    • Schaale, K.1    Neumann, J.2    Schneider, D.3    Ehlers, S.4    Reiling, N.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.