Proliferating or differentiating stimuli act on different lipid-dependent signaling pathways in nuclei of human leukemia cells

Molecular Biology of the Cell

Volumn 13, Issue 3, 2002, Pages 947-964

  Neri, Luca M ^a   Bortul, Roberta ^a   Borgatti, Paola ^a   Tabellini, Giovanna ^a   Baldini, Giovanna ^a   Capitani, Silvano ^a   Martelli, Alberto M ^a  

^a CNR   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 2,5 PYRROLIDINEDIONE; DIACYLGLYCEROL; DIMETHYL SULFOXIDE; EDELFOSINE; LIPID; NEOMYCIN; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE PHOSPHODIESTERASE; PHOSPHODIESTERASE INHIBITOR; PHOSPHOLIPASE D; PHOSPHOLIPASE D1; PHOSPHOLIPASE D2; PROPRANOLOL; PROTEIN KINASE C ALPHA; PROTEIN KINASE C BETA; PROTEIN KINASE C BETA II; SOMATOMEDIN C; SPHINGOSYLPHOSPHORYLCHOLINE; TRICYCLO[4.3.0.1]DECAN 9 YL XANTHOGENATE; UNCLASSIFIED DRUG;

ARTICLE; CELL DIFFERENTIATION; CELL NUCLEUS; CELL PROLIFERATION; CELL STIMULATION; CELL STRAIN HL 60; CONTROLLED STUDY; DRUG EFFECT; HUMAN; HUMAN CELL; LEUKEMIA CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TUMOR DIFFERENTIATION; TUMOR GROWTH;

CELL DIFFERENTIATION; CELL DIVISION; CELL FRACTIONATION; CELL NUCLEUS; DIGLYCERIDES; DIMETHYL SULFOXIDE; ETHANOL; HL-60 CELLS; HUMANS; INSULIN-LIKE GROWTH FACTOR I; ISOENZYMES; PHOSPHOLIPASE D; PHOSPHORYLCHOLINE; PROTEIN KINASE C; SIGNAL TRANSDUCTION; SOLVENTS; SPHINGOSINE; TETRADECANOYLPHORBOL ACETATE;

EID: 0036200219     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.01-02-0086     Document Type: Article

References (73)

1. Cytoplasmic and nuclear phospholipase C-β1 relocation: Role in resumption of meiosis in the mouse oocyte
2. Identification of the peptides that stimulate the phosphoinositide hydrolysis in lymphocyte cell lines from peptide libraries
3. A phospholipase D-mediated pathway for generating diacylglycerol in nuclei from Madin-Darby canine kidney cells
4. Nuclear phospholipase D in Madin-Darby canine kidney cells
5. Molecular species of phospholipids in a murine stem-cell line responsive to erythropoietin
6. 3 stimulates expression and translocation of protein kinase C α and δ via a non genomic mechanism and rapidly induces phosphorylation of a 33 kDa protein in acute promyelocytic NB4 cells
7. Intranuclear translocation of phospholipase C β2 during HL-60 myeloid differentiation
8. Control of expression of PLC β1 by LAC repressor system: Relationship between nuclear PLC β1 overexpression and growth factor stimulation
9. Phosphorylation of protein kinase C-α on serine 657 controls the accumulation of active enzyme and contributes to its phosphatase-resistant state
10. Differentiation of U937 cells enables a phospholipase D dependent pathway of cytosolic phospholipase A2 activation
11. Induction of apoptosis in human mitogen activated peripheral blood T-lymphocytes by the ether phospholipid ET-18-OCH3: Involvement of the Fas receptor/ligand system
12. Morphological differentiation of neuroblastoma cells by dimethylsulfoxide activation of lipid second messengers
13. Nuclear phospholipase C and signaling
14. The HL-60 promyelocytic leukemia cell line: Proliferation, differentiation, and cellular oncogene expression
15. The polyphosphoinositide cycle exists in the nuclei of Swiss 3T3 cells under the control of a receptor (for IGF-I) in the plasma membrane, and stimulation of the cycle increases nuclear diacylglycerol and apparently induces translocation of protein kinase C to the nucleus
16. Changes in the components of a nuclear inositide cycle during differentiation in murine erythroleukaemia cells
17. Een DAG uit het leven van de inositide signalering in de nucleus
18. Nuclei contain two differentially regulated pools of diacylglycerol
19. Phosphorylation at conserved carboxyl-terminal hydrophobic motif regulates the catalytic and regulatory domains of protein kinase C
20. Regulation of phospholipase D
21. An early decrease in phosphatidylinositol turnover occurs on induction of Friend cell differentiation and precedes the decrease in c-myc expression
22. Phosphorylation of lamin B at the nuclear membrane by activated protein kinase C
23. Interleukin-3 and bryostatin mediate rapid nuclear envelope phosphorylation in growth factor-dependent FDC-P1 hematopoietic cells
24. Intracellular localization of phospholipase D1 in mammalian cells
25. Role of Rho proteins in agonist regulation of phospholipase D in HL-60 cells
26. Selective translocation of βII-protein kinase C to the nucleus of human promyelocytic (HL-60) leukemia cells
27. Protein kinase C isotypes in human erythroleukemia cell proliferation and differentiation
28. Presence of a phospholipase D (PLD) distinct from PLD1 or PLD2 in human neutrophils: Immunobiochemical characterization and initial purification
29. Tyrosine kinase-regulated small GTPase translocation and the activation of phospholipase D in HL-60 granulocytes
30. α-thrombin associated nuclear sn-1,2-diacylglycerols are derived from phosphatidylcholine hydrolysis in cultured fibroblasts
31. Protein kinase C is regulated in vivo by three functionally distinct phosphorylations
32. Transmembrane signaling during erythropoietin- and dimethyl sulfoxide-induced erythroid differentiation
33. α-thrombin stimulates nuclear diglyceride kinase levels and differential nuclear localization of protein kinase C isozymes in IIC9 cells
34. Regulation of myeloid growth and differentiation by the insulin-like growth factor I receptor
35. Localization and possible functions of phospholipase D isozymes
36. Phospholipase D: Molecular and cellular biology of a novel gene family
37. Function of the p55 tumor necrosis factor receptor "death domain"mediated by phosphatidylcholine-specific phospholipase C
38. Protein kinase C α is an effector of hexamethylene bisacetamide-induced differentiation of Friend erythroleukemia cells
39. Erythropoietin stimulates nuclear localization of diacylglycerol and protein kinase C-βII in B6Eut.Ep cells
40. Essential role for nuclear phospholipase C β1 in insulin-like growth factor I-induced mitogenesis
41. Interleukin 1α stimulates nuclear phospholipase C in human osteosarcoma Saos-2 cells
42. Insulin selectively stimulates nuclear PI-PLC-β1 activity through a MAP kinase-dependent serine phosphorylation
43. Phosphatidylinositol 3-kinase translocates to the nucleus of osteoblast-like MC 3T3-E1 cells in response to insulin-like growth factor I, and platelet derived growth factor but not to the pro-apoptotic cytokine TNF-α
44. The pro-apoptotic drug camptothecin stimulates phospholipase D activity and diacylglycerol production in the nucleus of HL-60 human promyelocytic leukemia cells
45. The generation of lipid signaling molecules in the nucleus
46. Nuclear localization and signaling activity of phosphoinositidase C β1 in Swiss 3T3 cells
47. Multiple biological responses activated by nuclear protein kinase C
48. Nuclear but not cytoplasmic phospholipase C β1 inhibits differentiation of erythroleukemia cells
49. A rise and fall in 1,2 diacylglycerol content signal hexamethylene bisacetamide-induced erythropoiesis
50. Protein kinase C isotypes in human erythroleukemia cells
51. Distinct roles of erythropoietin, insulin-like growth factor I, and stem cell factor in the development of erythroid progenitor cells
52. + progenitor cells from human bone marrow
53. Nuclear diacylglycerol produced by phosphoinositide-specific phospholipase C is responsible for nuclear translocation of protein kinase C-α
54. Lipid signaling and cell responses at the nuclear level
55. Increase in nuclear phosphatidylinositol 3-kinase activity and phosphatidylinositol (3,4,5) trisphosphate synthesis precede PKC-ζ translocation to the nucleus of NGF-treated PC12 cells
56. IL-4 promotes macrophage development by rapidly stimulating lineage restriction of bipotent granulocyte-macrophage colony-forming cells
57. Regulation of membrane-bound phospholipase D by protein kinase C in HL-60 cells. Synergistic action of small GTP-binding protein RhoA
58. Tyrosine phosphorylation of 100-115 kDa proteins by phosphatidic acid generated via phospholipase D activation in HL-60 granulocytes
59. Pertussis toxin inhibits phospholipase C activation and Ca2+ mobilization by sphingosylphosphorylcholine and galactosylsphingosine in HL-60 leukemia cells
60. Inhibition of protein kinase C-do we, can we, and should we?
61. Diacylglycerol and phosphatidate generated by phospholipases C and D respectively have distinct fatty acid compositions and functions
62. Nuclear lipid metabolism in NEST: Nuclear envelope signal transduction
63. New insights into the regulation of protein kinase C and novel phorbol ester receptors
64. Inavasion of T-lymphoma cells: Cooperation between Rho family GTPases and lysophospholipid receptor signaling
65. 2/M phase transition
66. U-73122, a phospholipase C antagonist, inhibits effects of endothelin-1 and parathyroid hormone on signal transduction in UMR-106 osteoblastic cells
67. Phospholipase-D derived phosphatidic acid is involved in the activation of the CD11b/CD18 integrin in human eosinophils
68. Determination of in vivo phosphorylation sites in protein kinase C
69. Diacylglycerol-when is it an intracellular messenger?
70. Critical targets of protein kinase C in differentiation of tumor cells
71. Cytokine mediated PKC activation is a signal for lineage determination in bipotential granulocyte macrophage colony-forming cells
72. Nuclear phosphatidylinositols decrease during S-phase of the cell cycle in HeLa cells
73. Nuclear translocation of protein kinase C-α and -ζ isoforms in HL-60 cells induced to differentiate along the granulocytic lineage by all-trans-retinoic acid