-
1
-
-
0020554730
-
Mechanisms of insulin resistance in aging
-
Fink R.I., Kolterman O.G., Griffin J., Olefsky J.M. Mechanisms of insulin resistance in aging. Journal of Clinical Investigation 1983, 71:1523-1535.
-
(1983)
Journal of Clinical Investigation
, vol.71
, pp. 1523-1535
-
-
Fink, R.I.1
Kolterman, O.G.2
Griffin, J.3
Olefsky, J.M.4
-
2
-
-
2342475666
-
Polycomb complexes and silencing mechanisms
-
Lund A.H., van Lohuizen M. Polycomb complexes and silencing mechanisms. Current Opinion in Cell Biology 2004, 16:239-246. 10.1016/j.ceb.2004.03.010.
-
(2004)
Current Opinion in Cell Biology
, vol.16
, pp. 239-246
-
-
Lund, A.H.1
van Lohuizen, M.2
-
3
-
-
29144487990
-
Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing
-
Cao R., Tsukada Y.-I., Zhang Y. Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing. Molecular Cell 2005, 20:845-854. 10.1016/j.molcel.2005.12.002.
-
(2005)
Molecular Cell
, vol.20
, pp. 845-854
-
-
Cao, R.1
Tsukada, Y.-I.2
Zhang, Y.3
-
4
-
-
0033552813
-
The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus
-
Jacobs J.J., Kieboom K., Marino S., DePinho R.A., van Lohuizen M. The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus. Nature 1999, 397:164-168. 10.1038/16476.
-
(1999)
Nature
, vol.397
, pp. 164-168
-
-
Jacobs, J.J.1
Kieboom, K.2
Marino, S.3
DePinho, R.A.4
van Lohuizen, M.5
-
5
-
-
0025863346
-
Identification of cooperating oncogenes in E mu-myc transgenic mice by provirus tagging
-
van Lohuizen M., Verbeek S., Scheijen B., Wientjens E., van der Gulden H., Berns A. Identification of cooperating oncogenes in E mu-myc transgenic mice by provirus tagging. Cell 1991, 65:737-752.
-
(1991)
Cell
, vol.65
, pp. 737-752
-
-
van Lohuizen, M.1
Verbeek, S.2
Scheijen, B.3
Wientjens, E.4
van der Gulden, H.5
Berns, A.6
-
6
-
-
0033569429
-
Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF
-
Jacobs J.J.L., Scheijen B., Voncken J.-W., Kieboom K., Berns A., van Lohuizen M. Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF. Genes & Development 1999, 13:2678-2690.
-
(1999)
Genes & Development
, vol.13
, pp. 2678-2690
-
-
Jacobs, J.J.L.1
Scheijen, B.2
Voncken, J.-W.3
Kieboom, K.4
Berns, A.5
van Lohuizen, M.6
-
7
-
-
0037673984
-
Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells
-
Lessard J., Sauvageau G. Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells. Nature 2003, 423:255-260. 10.1038/nature01572.
-
(2003)
Nature
, vol.423
, pp. 255-260
-
-
Lessard, J.1
Sauvageau, G.2
-
8
-
-
0028201742
-
Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene
-
van der Lugt N.M., Domen J., Linders K., van Roon M., Robanus-Maandag E., te Riele H., et al. Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene. Genes & Development 1994, 8:757-769.
-
(1994)
Genes & Development
, vol.8
, pp. 757-769
-
-
van der Lugt, N.M.1
Domen, J.2
Linders, K.3
van Roon, M.4
Robanus-Maandag, E.5
te Riele, H.6
-
9
-
-
22344449361
-
Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways
-
Molofsky A.V., He S., Bydon M., Morrison S.J., Pardal R. Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways. Genes & Development 2005, 19:1432-1437. 10.1101/gad.1299505.
-
(2005)
Genes & Development
, vol.19
, pp. 1432-1437
-
-
Molofsky, A.V.1
He, S.2
Bydon, M.3
Morrison, S.J.4
Pardal, R.5
-
10
-
-
65249121864
-
Bmi-1 regulates the Ink4a/Arf locus to control pancreatic beta-cell proliferation
-
Dhawan S., Tschen S.-I., Bhushan A. Bmi-1 regulates the Ink4a/Arf locus to control pancreatic beta-cell proliferation. Genes & Development 2009, 23:906-911. 10.1101/gad.1742609.
-
(2009)
Genes & Development
, vol.23
, pp. 906-911
-
-
Dhawan, S.1
Tschen, S.-I.2
Bhushan, A.3
-
11
-
-
20544453888
-
Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice
-
Bruggeman S.W.M., Valk-Lingbeek M.E., van der Stoop P.P.M., Jacobs J.J.L., Kieboom K., Tanger E., et al. Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice. Genes & Development 2005, 19:1438-1443. 10.1101/gad.1299305.
-
(2005)
Genes & Development
, vol.19
, pp. 1438-1443
-
-
Bruggeman, S.W.M.1
Valk-Lingbeek, M.E.2
van der Stoop, P.P.M.3
Jacobs, J.J.L.4
Kieboom, K.5
Tanger, E.6
-
12
-
-
84873910684
-
Polycomb group response elements in drosophila and vertebrates
-
Kassis J.A., Brown J.L. Polycomb group response elements in drosophila and vertebrates. Advances in Genetics 2013, 81:83-118. 10.1016/B978-0-12-407677-8.00003-8.
-
(2013)
Advances in Genetics
, vol.81
, pp. 83-118
-
-
Kassis, J.A.1
Brown, J.L.2
-
13
-
-
84879222559
-
Embracing change to remain the same: conservation of polycomb functions despite divergence of binding motifs among species
-
Sharif J., Endo T.A., Ito S., Ohara O., Koseki H. Embracing change to remain the same: conservation of polycomb functions despite divergence of binding motifs among species. Current Opinion in Cell Biology 2013, 25:305-313. 10.1016/j.ceb.2013.02.009.
-
(2013)
Current Opinion in Cell Biology
, vol.25
, pp. 305-313
-
-
Sharif, J.1
Endo, T.A.2
Ito, S.3
Ohara, O.4
Koseki, H.5
-
14
-
-
0033636523
-
Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction
-
Michael M.D., Kulkarni R.N., Postic C., Previs S.F., Shulman G.I., Magnuson M.A., et al. Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction. Molecular Cell 2000, 6:87-97.
-
(2000)
Molecular Cell
, vol.6
, pp. 87-97
-
-
Michael, M.D.1
Kulkarni, R.N.2
Postic, C.3
Previs, S.F.4
Shulman, G.I.5
Magnuson, M.A.6
-
15
-
-
84859740874
-
Reduction of TIP47 improves hepatic steatosis and glucose homeostasis in mice
-
Carr R.M., Patel R.T., Rao V., Dhir R., Graham M.J., Crooke R.M., et al. Reduction of TIP47 improves hepatic steatosis and glucose homeostasis in mice. American Journal of Physiology - Regulatory, Integrative and Comparative Physiology 2012, 302:R996-R1003. 10.1152/ajpregu.00177.2011.
-
(2012)
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology
, vol.302
, pp. R996-R1003
-
-
Carr, R.M.1
Patel, R.T.2
Rao, V.3
Dhir, R.4
Graham, M.J.5
Crooke, R.M.6
-
16
-
-
84859117806
-
Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity
-
Lamming D.W., Ye L., Katajisto P., Goncalves M.D., Saitoh M., Stevens D.M., et al. Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity. Science 2012, 335:1638-1643. 10.1126/science.1215135.
-
(2012)
Science
, vol.335
, pp. 1638-1643
-
-
Lamming, D.W.1
Ye, L.2
Katajisto, P.3
Goncalves, M.D.4
Saitoh, M.5
Stevens, D.M.6
-
17
-
-
84862025421
-
Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration
-
Sun Z., Miller R.A., Patel R.T., Chen J., Dhir R., Wang H., et al. Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration. Nature Medicine 2012, 18:934-942. 10.1038/nm.2744.
-
(2012)
Nature Medicine
, vol.18
, pp. 934-942
-
-
Sun, Z.1
Miller, R.A.2
Patel, R.T.3
Chen, J.4
Dhir, R.5
Wang, H.6
-
18
-
-
79957902675
-
Adiponectin suppresses gluconeogenic gene expression in mouse hepatocytes independent of LKB1-AMPK signaling
-
Miller R.A., Chu Q., Le Lay J., Scherer P.E., Ahima R.S., Kaestner K.H., et al. Adiponectin suppresses gluconeogenic gene expression in mouse hepatocytes independent of LKB1-AMPK signaling. Journal of Clinical Investigation 2011, 121:2518-2528. 10.1172/JCI45942.
-
(2011)
Journal of Clinical Investigation
, vol.121
, pp. 2518-2528
-
-
Miller, R.A.1
Chu, Q.2
Le Lay, J.3
Scherer, P.E.4
Ahima, R.S.5
Kaestner, K.H.6
-
19
-
-
66649084335
-
Age-dependent decline in beta-cell proliferation restricts the capacity of beta-cell regeneration in mice
-
Tschen S.-I., Dhawan S., Gurlo T., Bhushan A. Age-dependent decline in beta-cell proliferation restricts the capacity of beta-cell regeneration in mice. Diabetes 2009, 58:1312-1320. 10.2337/db08-1651.
-
(2009)
Diabetes
, vol.58
, pp. 1312-1320
-
-
Tschen, S.-I.1
Dhawan, S.2
Gurlo, T.3
Bhushan, A.4
-
20
-
-
84866981249
-
Bmi1 is required for hepatic progenitor cell expansion and liver tumor development
-
Fan L., Xu C., Wang C., Tao J., Ho C., Jiang L., et al. Bmi1 is required for hepatic progenitor cell expansion and liver tumor development. PLoS One 2012, 7:e46472. 10.1371/journal.pone.0046472.
-
(2012)
PLoS One
, vol.7
, pp. e46472
-
-
Fan, L.1
Xu, C.2
Wang, C.3
Tao, J.4
Ho, C.5
Jiang, L.6
-
21
-
-
84877836210
-
Vivo RNAi screen for BMI1 targets identifies TGF-β/BMP-ER stress pathways as key regulators of neural- and malignant glioma-stem cell homeostasis
-
Gargiulo G., Cesaroni M., Serresi M., de Vries N., Hulsman D., Bruggeman S.W., et al. Vivo RNAi screen for BMI1 targets identifies TGF-β/BMP-ER stress pathways as key regulators of neural- and malignant glioma-stem cell homeostasis. Cancer Cell 2013, 23:660-676. 10.1016/j.ccr.2013.03.030.
-
(2013)
Cancer Cell
, vol.23
, pp. 660-676
-
-
Gargiulo, G.1
Cesaroni, M.2
Serresi, M.3
de Vries, N.4
Hulsman, D.5
Bruggeman, S.W.6
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