Disturbed biopterin and folate metabolism in the Qdpr-deficient mouse

FEBS Letters

Volumn 588, Issue 21, 2014, Pages 3924-3931

  Xu, Feng ^a   Sudo, Yusuke ^a   Sanechika, Sho ^a   Yamashita, Junpei ^a   Shimaguchi, Sho ^a   Honda, Shun Ichiro ^a   Sumi Ichinose, Chiho ^b   Mori Kojima, Masayo ^c   Nakata, Rieko ^d   Furuta, Tadaomi ^a   Sakurai, Minoru ^a   Sugimoto, Masahiro ^c   Soga, Tomoyoshi ^c   Kondo, Kazunao ^b   Ichinose, Hiroshi ^a  

^a TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^b FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c KEIO UNIVERSITY   (Japan)

^d NARA WOMEN'S UNIVERSITY   (Japan)

Author keywords

Dihydrofolate reductase; Folate; Oxidative stress; Quinonoid dihydropteridine reductase; Tetrahydrobiopterin

Indexed keywords

BIOPTERIN; DIHYDROBIOPTERIN; DIHYDROFOLATE REDUCTASE; DIHYDROPTERIDINE REDUCTASE; FOLIC ACID; NEOPTERIN; TETRAHYDROBIOPTERIN; DIHYDROFOLIC ACID; METHOTREXATE; OXIDOREDUCTASE; QUINONOID DIHYDROPTERIN REDUCTASE; SAPROPTERIN;

AMINOHYDROXYLATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FOLATE METABOLISM; GENETIC DISORDER; IN VIVO STUDY; INHIBITION KINETICS; METABOLOMICS; MOLECULAR INTERACTION; MOUSE; NONHUMAN; QDPR GENE; QUINONOID DIHYDROPTERIDINE REDUCTASE DEFICIENCY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANIMAL; DEFICIENCY; GENETICS; KINETICS; METABOLISM; TRANSGENIC MOUSE;

ANIMALS; BIOPTERIN; FOLIC ACID; KINETICS; METABOLOMICS; METHOTREXATE; MICE; MICE, TRANSGENIC; OXIDOREDUCTASES; TETRAHYDROFOLATE DEHYDROGENASE;

EID: 84908242249     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2014.09.004     Document Type: Article

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