Knockdown of peroxiredoxin 5 inhibits the growth of osteoarthritic chondrocytes via upregulating Wnt/β-catenin signaling

Free Radical Biology and Medicine

Volumn 76, Issue , 2014, Pages 251-260

  Ma, Yini ^a   Li, Rongheng ^a   Zhang, Yudi ^a   Zhou, Lingyun ^a   Dai, Yehong ^a  

^a THE FIRST AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Cartilage; Chondrocytes; Osteoarthritis; Peroxiredoxin 5; Reactive oxygen species

Indexed keywords

7,8 DIHYDRO 2 [4 (TRIFLUOROMETHYL)PHENYL] 5H THIOPYRANO[4,3 D]PYRIMIDIN 4 OL; BETA CATENIN; COLLAGENASE 3; GLYCOGEN SYNTHASE KINASE 3BETA; PEROXIREDOXIN 5; REACTIVE OXYGEN METABOLITE; T CELL FACTOR PROTEIN; WNT PROTEIN; MESSENGER RNA; MMP13 PROTEIN, HUMAN; PEROXIREDOXIN; PRDX5 PROTEIN, HUMAN; SMALL INTERFERING RNA;

APOPTOSIS; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; FLOW CYTOMETRY; GENE SILENCING; GENETIC TRANSFECTION; GROWTH INHIBITION; HUMAN; HUMAN CELL; MTT ASSAY; OSTEOARTHRITIC CHONDROCYTE; OSTEOARTHRITIS; PATHOGENESIS; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING; WNT SIGNALING PATHWAY; ANTAGONISTS AND INHIBITORS; CASE CONTROL STUDY; CELL CULTURE; CELL PROLIFERATION; CYTOLOGY; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; METABOLISM; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

APOPTOSIS; BETA CATENIN; BLOTTING, WESTERN; CASE-CONTROL STUDIES; CELL PROLIFERATION; CELLS, CULTURED; CHONDROCYTES; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; MATRIX METALLOPROTEINASE 13; OSTEOARTHRITIS; PEROXIREDOXINS; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; UP-REGULATION; WNT PROTEINS;

EID: 84908223203     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2014.08.015     Document Type: Article

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