Crystal structure of human peroxiredoxin 5, a novel type of mammalian peroxiredoxin at 1.5 Å resolution

Journal of Molecular Biology

Volumn 311, Issue 4, 2001, Pages 751-759

  Declercq, Jean Paul ^a   Evrard, Christine ^a   Clippe, André ^a   Stricht, Delphine Vander ^a   Bernard, Alfred ^a   Knoops, Bernard ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

Antioxidant enzyme; Crystal structure; Peroxiredoxin; Thioredoxin fold; Thioredoxin peroxidase

Indexed keywords

ANTIOXIDANT; PEROXIREDOXIN; PEROXIREDOXIN 5; UNCLASSIFIED DRUG;

ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; HUMAN; MAMMAL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PURIFICATION; STRUCTURE ANALYSIS;

EUKARYOTA; MAMMALIA; PROKARYOTA;

EID: 0035943382     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2001.4853     Document Type: Article

References (29)

1. Cloning and sequencing of thiol-specific antioxidant from mammalian brain: Alkyl hydroperoxide reductase and thiol-specific antioxidant define a large family of antioxidant enzymes
2. Identification of a new type of mammalian peroxiredoxin that forms an intramolecular disulfide as a reaction intermediate
3. Mouse peroxiredoxin V is a thioredoxin peroxidase that inhibits p53-induced apoptosis
4. A novel human DNA-binding protein with sequence similarity to a subfamily of redox proteins which is able to repress RNA-polymerase-III-driven transcription of the Alu-family retroposons in vitro
5. Characterization of human and murine PMP20 peroxisomal proteins that exhibit antioxidant activity in vitro
6. Cloning and characterization of AOEB166, a novel mammalian antioxidant enzyme of the peroxiredoxin family
7. Peroxinitrite reductase activity of bacterial peroxiredoxins
8. Thioredoxin - A fold for all reasons
9. Crystal structure of a novel human peroxidase enzyme at 2.0 Å resolution
10. Crystal structure of a multifunctional 2-Cys peroxiredoxin heme-binding protein 23 kDa/proliferation-associated gene product
11. Crystal structure of decameric 2-Cys peroxiredoxin from human erythrocytes at 1.7 Å resolution
12. Detecting folding motifs and similarities in protein structures
13. Improved methods for building protein models in electron-density maps and the location of errors in these models
14. Regulatory role for a novel human thioredoxin peroxidase in NF-kappaB activation
15. A new method for the detection of hydroxyl radical production by phagocytic cells
16. Novel approach to phasing proteins: Derivatization by short cryo-soaking with halides
17. Processing of X-ray diffraction data collected in oscillation mode
18. The free R value: A novel statistical quantity for assessing the accuracy of crystal structures
19. The application of direct methods and Patterson interpretation to high-resolution native protein data
20. The CCP4 suite: Programs for protein crystallography
21. Maximum likelihood refinement of heavy atom parameters
22. DM, an automated procedure for phase improvement by density modification
23. Automated protein model building combined with iterative structure refinement
24. SHELXL: High-resolution refinement
25. PROCHECK: A program to check the stereochemical quality of protein structures
26. MOLSCRIPT: A program to produce both detailed and schematic plots of protein structures
27. Raster3D: Photo-realistic molecular graphics
28. Improved Fourier coefficients for maps using phases from partial structures with error
29. GRASP: Graphical representation and analysis of surface properties