The LQLP calcineurin docking site is a major determinant of the calcium-dependent activation of human TRESK background K+ channel

Journal of Biological Chemistry

Volumn 289, Issue 43, 2014, Pages 29506-29518

  Czirják, Gábor ^a   Enyedi, Péter ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BINDING ENERGY; CHEMICAL ACTIVATION;

ALANINE SUBSTITUTION; AMINO ACID SEQUENCE; BINDING AFFINITIES; CALCIUM CONCENTRATION; CONSENSUS SEQUENCE; DOCKING SITES; HIGH CALCIUMS; SEQUENCE MODIFICATION;

CALCIUM;

ALANINE; CALCINEURIN; CALCIUM; DOCKING PROTEIN; LQLP CALCINEURIN DOCKING SITE; MUTANT PROTEIN; POTASSIUM CHANNEL; TRANSCRIPTION FACTOR NFAT; TRESK PROTEIN; UNCLASSIFIED DRUG; KCNK18 PROTEIN, HUMAN; PROTEIN BINDING;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CALCIUM CELL LEVEL; CYTOPLASM; CYTOPLASMIC CALCIUM CONCENTRATION; MOUSE; MUTATION; NONHUMAN; WILD TYPE; ANIMAL; BINDING SITE; BIOLOGICAL MODEL; CHANNEL GATING; CHEMISTRY; DRUG EFFECTS; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; PHOSPHORYLATION; PROTEIN MOTIF; STRUCTURE ACTIVITY RELATION;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CALCINEURIN; CALCIUM; HUMANS; ION CHANNEL GATING; MICE; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; MUTATION; PHOSPHORYLATION; POTASSIUM CHANNELS; PROTEIN BINDING; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84908199248     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.577684     Document Type: Article

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