Symplekin promotes tumorigenicity by up-regulating claudin-2 expression

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 6, 2010, Pages 2628-2633

  Buchert, Michael ^a,b,c,f   Papin, Marina ^a,b,c   Bonnans, Caroline ^a,b,c   Darido, Charbel ^a,b,c,g   Raye, Warren S ^d   Garambois, Véronique ^b   Pélegrin, André ^b   Bourgaux, Jean François ^e   Pannequin, Julie ^e   Joubert, Dominique ^a,b,c   Hollande, Frédéric ^a,b,c,d  

^a INSTITUT DE GÉNOMIQUE FONCTIONNELLE   (France)

^b INSERM   (France)

^c UNIV MONTPELLIER   (France)

^d MONASH UNIVERSITY   (Australia)

^e DEPARTMENT OF NEUROLOGY   (France)

^f LUDWIG INSTITUTE FOR CANCER RESEARCH   (Australia)

^g ROYAL MELBOURNE HOSPITAL   (Australia)

Author keywords

Colorectal; Polarity; Tight junctions; Transcription; Tumorigenesis

Indexed keywords

CLAUDIN 2; CYCLIN D1; NUCLEAR PROTEIN; NUCLEIC ACID BINDING PROTEIN; PROTEIN SYMPLEKIN; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; ZONULA OCCLUDENS 1 ASSOCIATED NUCLEIC ACID BINDING PROTEIN;

ARTICLE; CANCER CELL; CANCER GROWTH; CANCER INHIBITION; CARCINOGENICITY; CELL POLARITY; CELL PROLIFERATION; CELL TRANSPORT; COLORECTAL CANCER; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN TISSUE; ION TRANSPORT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; TIGHT JUNCTION;

ANIMALS; BLOTTING, WESTERN; CCAAT-ENHANCER-BINDING PROTEINS; CELL PROLIFERATION; COLORECTAL NEOPLASMS; CYCLIN D1; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION, NEOPLASTIC; HEAT-SHOCK PROTEINS; HT29 CELLS; HUMANS; MEMBRANE PROTEINS; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASMS, EXPERIMENTAL; NUCLEAR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TRANSPLANTATION, HETEROLOGOUS; TUMOR BURDEN; UP-REGULATION;

ANIMALIA;

EID: 77249166583     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0903747107     Document Type: Article

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