Chronic Central Nervous System Expression of HIV-1 Tat Leads to Accelerated Rarefaction of Neocortical Capillaries and Loss of Red Blood Cell Velocity Heterogeneity

Microcirculation

Volumn 21, Issue 7, 2014, Pages 664-676

  Silva, Jharon N ^a   Polesskaya, Oksana ^a   Wei, Helen S ^a   Rasheed, Izad Yar D ^b   Chamberlain, Jeffrey M ^a   Nishimura, Christopher ^a   Feng, Changyong ^a   Dewhurst, Stephen ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Capillary rarefaction; Cerebrovascular; HIV 1; Red blood cell velocity; Tat transgenic mice

Indexed keywords

INTERLEUKIN 1BETA; TRANSACTIVATOR PROTEIN; VASCULOTROPIN; DOXYCYCLINE; HYBRID PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL PH; ARTICLE; BRAIN CAPILLARY; BRAIN TISSUE; CAPILLARY DENSITY; CELL DENSITY; CONTROLLED STUDY; ERYTHROCYTE; HUMAN IMMUNODEFICIENCY VIRUS 1; IN VIVO STUDY; LONG TERM EXPOSURE; MALE; MOUSE; MULTIPHOTON MICROSCOPY; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; STEADY STATE; ANGIOGENESIS; ANIMAL; ASTROCYTE; BLOOD FLOW VELOCITY; CAPILLARY; DRUG EFFECTS; GENETICS; HEMODYNAMICS; MEAN CORPUSCULAR VOLUME; METABOLISM; NEOCORTEX; PATHOLOGY; REGULATOR GENE; TRANSGENIC MOUSE; UPREGULATION; VASCULARIZATION;

ANIMALS; ASTROCYTES; BLOOD FLOW VELOCITY; CAPILLARIES; DOXYCYCLINE; ERYTHROCYTE INDICES; GENES, TAT; HEMODYNAMICS; HIV-1; MALE; MICE; MICE, TRANSGENIC; MICROSCOPY, FLUORESCENCE, MULTIPHOTON; NEOCORTEX; NEOVASCULARIZATION, PHYSIOLOGIC; PYRAMIDAL CELLS; RECOMBINANT FUSION PROTEINS; TAT GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; UP-REGULATION;

EID: 84908154265     PISSN: 10739688     EISSN: 15498719     Source Type: Journal    
DOI: 10.1111/micc.12145     Document Type: Article

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