메뉴 건너뛰기




Volumn 4, Issue 3, 2012, Pages 302-315

HIV-1 Tat-induced microglial activation and neuronal damage is inhibited via CD45 modulation: A potential new treatment target for HAND

Author keywords

CD45; Dementia; HIV; HIV associated neurocognitive disorders; Microglia

Indexed keywords

CD45 ANTIBODY; CD45 ANTIGEN; INTERLEUKIN 1BETA; LYMPHOCYTE ANTIBODY; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MONOCLONAL ANTIBODY; POTASSIUM BISPEROXO(1,10 PHENANTHROLINE)OXOVANADATE; TRANSACTIVATOR PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VANADIC ACID;

EID: 84865096921     PISSN: None     EISSN: 19438141     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (24)

References (66)
  • 1
    • 77952940200 scopus 로고    scopus 로고
    • Human immunodeficiency virus-associated neurocognitive disorders: Mind the gap
    • McArthur JC, Steiner J, Sacktor N and Nath A. Human immunodeficiency virus-associated neurocognitive disorders: Mind the gap. Ann Neurol 67: 699-714.
    • Ann Neurol , vol.67 , pp. 699-714
    • McArthur, J.C.1    Steiner, J.2    Sacktor, N.3    Nath, A.4
  • 11
    • 39149143342 scopus 로고    scopus 로고
    • Immune activation of the central nervous system is still present after >4 years of effective highly active antiretroviral therapy
    • Eden A, Price RW, Spudich S, Fuchs D, Hagberg L and Gisslen M. Immune activation of the central nervous system is still present after >4 years of effective highly active antiretroviral therapy. J Infect Dis 2007; 196: 1779-1783.
    • (2007) J Infect Dis , vol.196 , pp. 1779-1783
    • Eden, A.1    Price, R.W.2    Spudich, S.3    Fuchs, D.4    Hagberg, L.5    Gisslen, M.6
  • 12
    • 0028808135 scopus 로고
    • Immunocytochemical quantitation of human immunodeficiency virus in the brain: Correlations with dementia
    • Glass JD, Fedor H, Wesselingh SL and McArthur JC. Immunocytochemical quantitation of human immunodeficiency virus in the brain: correlations with dementia. Ann Neurol 1995; 38: 755-762.
    • (1995) Ann Neurol , vol.38 , pp. 755-762
    • Glass, J.D.1    Fedor, H.2    Wesselingh, S.L.3    McArthur, J.C.4
  • 14
    • 81455135889 scopus 로고    scopus 로고
    • Dimethyl fumarate, an immune modulator and inducer of the antioxidant response, suppresses HIV replication and macrophagemediated neurotoxicity: A novel candidate for HIV neuroprotection
    • Cross SA, Cook DR, Chi AW, Vance PJ, Kolson LL, Wong BJ, Jordan-Sciutto KL and Kolson DL. Dimethyl fumarate, an immune modulator and inducer of the antioxidant response, suppresses HIV replication and macrophagemediated neurotoxicity: a novel candidate for HIV neuroprotection. J Immunol 187: 5015-5025.
    • J Immunol , vol.187 , pp. 5015-5025
    • Cross, S.A.1    Cook, D.R.2    Chi, A.W.3    Vance, P.J.4    Kolson, L.L.5    Wong, B.J.6    Jordan-Sciutto, K.L.7    Kolson, D.L.8
  • 16
    • 33645579949 scopus 로고    scopus 로고
    • Developments in HIV neuropathogenesis
    • Rumbaugh JA and Nath A. Developments in HIV neuropathogenesis. Curr Pharm Des 2006; 12: 1023-1044.
    • (2006) Curr Pharm Des , vol.12 , pp. 1023-1044
    • Rumbaugh, J.A.1    Nath, A.2
  • 20
    • 1942486751 scopus 로고    scopus 로고
    • Expression of chemokines by human fetal microglia after treatment with the human immunodeficiency virus type 1 protein Tat
    • D'Aversa TG, Yu KO and Berman JW. Expression of chemokines by human fetal microglia after treatment with the human immunodeficiency virus type 1 protein Tat. J Neurovirol 2004; 10: 86-97.
    • (2004) J Neurovirol , vol.10 , pp. 86-97
    • D'Aversa, T.G.1    Yu, K.O.2    Berman, J.W.3
  • 21
    • 14844358547 scopus 로고    scopus 로고
    • HIV-1 tat protein induces a migratory phenotype in human fetal microglia by a CCL2 (MCP-1)-dependent mechanism: Possible role in NeuroAIDS
    • Eugenin EA, Dyer G, Calderon TM and Berman JW. HIV-1 tat protein induces a migratory phenotype in human fetal microglia by a CCL2 (MCP-1)-dependent mechanism: possible role in NeuroAIDS. Glia 2005; 49: 501-510.
    • (2005) Glia , vol.49 , pp. 501-510
    • Eugenin, E.A.1    Dyer, G.2    Calderon, T.M.3    Berman, J.W.4
  • 22
    • 0038815306 scopus 로고    scopus 로고
    • CD45: A critical regulator of signaling thresholds in immune cells
    • Hermiston ML, Xu Z and Weiss A. CD45: a critical regulator of signaling thresholds in immune cells. Annu Rev Immunol 2003; 21: 107-137.
    • (2003) Annu Rev Immunol , vol.21 , pp. 107-137
    • Hermiston, M.L.1    Xu, Z.2    Weiss, A.3
  • 23
    • 33751161009 scopus 로고    scopus 로고
    • CD45 isoform expression in microglia and inflammatory cells in HIV-1 encephalitis
    • Cosenza-Nashat MA, Kim MO, Zhao ML, Suh HS and Lee SC. CD45 isoform expression in microglia and inflammatory cells in HIV-1 encephalitis. Brain Pathol 2006; 16: 256-265.
    • (2006) Brain Pathol , vol.16 , pp. 256-265
    • Cosenza-Nashat, M.A.1    Kim, M.O.2    Zhao, M.L.3    Suh, H.S.4    Lee, S.C.5
  • 27
    • 0023636055 scopus 로고
    • Differential usage of three exons generates at least five different mRNAs encoding human leukocyte common antigens
    • Streuli M, Hall LR, Saga Y, Schlossman SF and Saito H. Differential usage of three exons generates at least five different mRNAs encoding human leukocyte common antigens. J Exp Med 1987; 166: 1548-1566.
    • (1987) J Exp Med , vol.166 , pp. 1548-1566
    • Streuli, M.1    Hall, L.R.2    Saga, Y.3    Schlossman, S.F.4    Saito, H.5
  • 28
    • 0028261779 scopus 로고
    • Expression of MRP14, 27E10, interferon-alpha and leukocyte common antigen by reactive microglia in postmortem human brain tissue
    • Akiyama H, Ikeda K, Katoh M, McGeer EG and McGeer PL. Expression of MRP14, 27E10, interferon-alpha and leukocyte common antigen by reactive microglia in postmortem human brain tissue. J Neuroimmunol 1994; 50: 195-201.
    • (1994) J Neuroimmunol , vol.50 , pp. 195-201
    • Akiyama, H.1    Ikeda, K.2    Katoh, M.3    McGeer, E.G.4    McGeer, P.L.5
  • 29
    • 0036795863 scopus 로고    scopus 로고
    • Human brain parenchymal microglia express CD14 and CD45 and are productively infected by HIV-1 in HIV-1 encephalitis
    • Cosenza MA, Zhao ML, Si Q and Lee SC. Human brain parenchymal microglia express CD14 and CD45 and are productively infected by HIV-1 in HIV-1 encephalitis. Brain Pathol 2002; 12: 442-455.
    • (2002) Brain Pathol , vol.12 , pp. 442-455
    • Cosenza, M.A.1    Zhao, M.L.2    Si, Q.3    Lee, S.C.4
  • 30
    • 0035004684 scopus 로고    scopus 로고
    • Diminished adenosine A1 receptor expression on macro phages in brain and blood of patients with multiple sclerosis
    • Johnston JB, Silva C, Gonzalez G, Holden J, Warren KG, Metz LM and Power C. Diminished adenosine A1 receptor expression on macro phages in brain and blood of patients with multiple sclerosis. Ann Neurol 2001; 49: 650-658.
    • (2001) Ann Neurol , vol.49 , pp. 650-658
    • Johnston, J.B.1    Silva, C.2    Gonzalez, G.3    Holden, J.4    Warren, K.G.5    Metz, L.M.6    Power, C.7
  • 31
    • 0032146242 scopus 로고    scopus 로고
    • Increased levels of alpha-1-antichymotrypsin in brains of patients with Alzheimer's disease correlate with activated astrocytes and are affected by APOE 4 genotype
    • Licastro F, Mallory M, Hansen LA and Masliah E. Increased levels of alpha-1-antichymotrypsin in brains of patients with Alzheimer's disease correlate with activated astrocytes and are affected by APOE 4 genotype. J Neuroimmunol 1998; 88: 105-110.
    • (1998) J Neuroimmunol , vol.88 , pp. 105-110
    • Licastro, F.1    Mallory, M.2    Hansen, L.A.3    Masliah, E.4
  • 33
    • 0032103936 scopus 로고    scopus 로고
    • Central nervous system microglial cell activation and proliferation follows direct interaction with tissue-infiltrating T cell blasts
    • Sedgwick JD, Ford AL, Foulcher E and Airriess R. Central nervous system microglial cell activation and proliferation follows direct interaction with tissue-infiltrating T cell blasts. J Immunol 1998; 160: 5320-5330.
    • (1998) J Immunol , vol.160 , pp. 5320-5330
    • Sedgwick, J.D.1    Ford, A.L.2    Foulcher, E.3    Airriess, R.4
  • 34
    • 0034667558 scopus 로고    scopus 로고
    • CD45 opposes beta-amyloid peptide-induced microglial activation via inhibition of p44/42 mitogen-activated protein kinase
    • Tan J, Town T, Mori T, Wu Y, Saxe M, Crawford F and Mullan M. CD45 opposes beta-amyloid peptide-induced microglial activation via inhibition of p44/42 mitogen-activated protein kinase. J Neurosci 2000; 20: 7587-7594.
    • (2000) J Neurosci , vol.20 , pp. 7587-7594
    • Tan, J.1    Town, T.2    Mori, T.3    Wu, Y.4    Saxe, M.5    Crawford, F.6    Mullan, M.7
  • 35
    • 0034711317 scopus 로고    scopus 로고
    • CD45 inhibits CD40L-induced microglial activation via negative regulation of the Src/p44/42 MAPK pathway
    • Tan J, Town T and Mullan M. CD45 inhibits CD40L-induced microglial activation via negative regulation of the Src/p44/42 MAPK pathway. J Biol Chem 2000; 275: 37224-37231.
    • (2000) J Biol Chem , vol.275 , pp. 37224-37231
    • Tan, J.1    Town, T.2    Mullan, M.3
  • 36
    • 14044264203 scopus 로고    scopus 로고
    • Inhibition of granulocyte-macrophage colony-stimulating factor signaling and microglial proliferation by anti-CD45RO: Role of Hck tyrosine kinase and phosphatidylinositol 3-kinase/Akt
    • Suh HS, Kim MO and Lee SC. Inhibition of granulocyte-macrophage colony-stimulating factor signaling and microglial proliferation by anti-CD45RO: role of Hck tyrosine kinase and phosphatidylinositol 3-kinase/Akt. J Immunol 2005; 174: 2712-2719.
    • (2005) J Immunol , vol.174 , pp. 2712-2719
    • Suh, H.S.1    Kim, M.O.2    Lee, S.C.3
  • 37
    • 33645980955 scopus 로고    scopus 로고
    • Anti-CD45RO suppresses human immunodeficiency virus type 1 replication in microglia: Role of Hck tyrosine kinase and implications for AIDS dementia
    • Kim MO, Suh HS, Si Q, Terman BI and Lee SC. Anti-CD45RO suppresses human immunodeficiency virus type 1 replication in microglia: role of Hck tyrosine kinase and implications for AIDS dementia. J Virol 2006; 80: 62-72.
    • (2006) J Virol , vol.80 , pp. 62-72
    • Kim, M.O.1    Suh, H.S.2    Si, Q.3    Terman, B.I.4    Lee, S.C.5
  • 38
    • 77951002550 scopus 로고    scopus 로고
    • Mechanism of HIV-1-TAT induction of interleukin-1beta from human monocytes: Involvement of the phospholipase C/protein kinase C signaling cascade
    • Yang Y, Wu J and Lu Y. Mechanism of HIV-1-TAT induction of interleukin-1beta from human monocytes: Involvement of the phospholipase C/protein kinase C signaling cascade. J Med Virol 82: 735-746.
    • J Med Virol , vol.82 , pp. 735-746
    • Yang, Y.1    Wu, J.2    Lu, Y.3
  • 39
    • 4444232329 scopus 로고    scopus 로고
    • Galantamine and nicotine have a synergistic effect on inhibition of microglial activation induced by HIV-1 gp120
    • Giunta B, Ehrhart J, Townsend K, Sun N, Vendrame M, Shytle D, Tan J and Fernandez F. Galantamine and nicotine have a synergistic effect on inhibition of microglial activation induced by HIV-1 gp120. Brain Res Bull 2004; 64: 165-170.
    • (2004) Brain Res Bull , vol.64 , pp. 165-170
    • Giunta, B.1    Ehrhart, J.2    Townsend, K.3    Sun, N.4    Vendrame, M.5    Shytle, D.6    Tan, J.7    Fernandez, F.8
  • 40
    • 0035863722 scopus 로고    scopus 로고
    • HIV-1 Tat promotes monocyte chemoattractant protein-1 secretion followed by transmigration of monocytes
    • Park IW, Wang JF and Groopman JE. HIV-1 Tat promotes monocyte chemoattractant protein-1 secretion followed by transmigration of monocytes. Blood 2001; 97: 352-358.
    • (2001) Blood , vol.97 , pp. 352-358
    • Park, I.W.1    Wang, J.F.2    Groopman, J.E.3
  • 41
    • 0032581714 scopus 로고    scopus 로고
    • HIV-1 Tat induces tyrosine phosphorylation of p125FAK and its association with phosphoinositide 3-kinase in PC12 cells
    • Milani D, Mazzoni M, Zauli G, Mischiati C, Gibellini D, Giacca M and Capitani S. HIV-1 Tat induces tyrosine phosphorylation of p125FAK and its association with phosphoinositide 3-kinase in PC12 cells. Aids 1998; 12: 1275-1284.
    • (1998) Aids , vol.12 , pp. 1275-1284
    • Milani, D.1    Mazzoni, M.2    Zauli, G.3    Mischiati, C.4    Gibellini, D.5    Giacca, M.6    Capitani, S.7
  • 42
    • 0034034925 scopus 로고    scopus 로고
    • HIV-1 Tat increases endothelial solute permeability through tyrosine kinase and mitogenactivated protein kinase-dependent pathways
    • Oshima T, Flores SC, Vaitaitis G, Coe LL, Joh T, Park JH, Zhu Y, Alexander B and Alexander JS. HIV-1 Tat increases endothelial solute permeability through tyrosine kinase and mitogenactivated protein kinase-dependent pathways. Aids 2000; 14: 475-482.
    • (2000) Aids , vol.14 , pp. 475-482
    • Oshima, T.1    Flores, S.C.2    Vaitaitis, G.3    Coe, L.L.4    Joh, T.5    Park, J.H.6    Zhu, Y.7    Alexander, B.8    Alexander, J.S.9
  • 43
    • 8444227370 scopus 로고    scopus 로고
    • HIV-1 Tat-mediated effects on focal adhesion assembly and permeability in brain microvascular endothelial cells
    • Avraham HK, Jiang S, Lee TH, Prakash O and Avraham S. HIV-1 Tat-mediated effects on focal adhesion assembly and permeability in brain microvascular endothelial cells. J Immunol 2004; 173: 6228-6233.
    • (2004) J Immunol , vol.173 , pp. 6228-6233
    • Avraham, H.K.1    Jiang, S.2    Lee, T.H.3    Prakash, O.4    Avraham, S.5
  • 48
    • 0344444234 scopus 로고    scopus 로고
    • Distribution of major histocompatibility complex class IIpositive microglia and cytokine profile of Parkinson's disease brains
    • Imamura K, Hishikawa N, Sawada M, Nagatsu T, Yoshida M and Hashizume Y. Distribution of major histocompatibility complex class IIpositive microglia and cytokine profile of Parkinson's disease brains. Acta Neuropathol 2003; 106: 518-526.
    • (2003) Acta Neuropathol , vol.106 , pp. 518-526
    • Imamura, K.1    Hishikawa, N.2    Sawada, M.3    Nagatsu, T.4    Yoshida, M.5    Hashizume, Y.6
  • 50
    • 14744296610 scopus 로고    scopus 로고
    • Inflammatory process in Parkinson's disease: Role for cytokines
    • Nagatsu T and Sawada M. Inflammatory process in Parkinson's disease: role for cytokines. Curr Pharm Des 2005; 11: 999-1016.
    • (2005) Curr Pharm Des , vol.11 , pp. 999-1016
    • Nagatsu, T.1    Sawada, M.2
  • 52
    • 0035879378 scopus 로고    scopus 로고
    • Microglia in HIVassociated neurological diseases
    • Glass JD and Wesselingh SL. Microglia in HIVassociated neurological diseases. Microsc Res Tech 2001; 54: 95-105.
    • (2001) Microsc Res Tech , vol.54 , pp. 95-105
    • Glass, J.D.1    Wesselingh, S.L.2
  • 53
    • 34248392684 scopus 로고    scopus 로고
    • Microglial activation and its implications in the brain diseases
    • Dheen ST, Kaur C and Ling EA. Microglial activation and its implications in the brain diseases. Curr Med Chem 2007; 14: 1189-1197.
    • (2007) Curr Med Chem , vol.14 , pp. 1189-1197
    • Dheen, S.T.1    Kaur, C.2    Ling, E.A.3
  • 54
    • 0025855799 scopus 로고
    • Gamma-interferon promotes differentiation of cultured cortical and hippocampal neurons
    • Barish ME, Mansdorf NB and Raissdana SS. Gamma-interferon promotes differentiation of cultured cortical and hippocampal neurons. Dev Biol 1991; 144: 412-423.
    • (1991) Dev Biol , vol.144 , pp. 412-423
    • Barish, M.E.1    Mansdorf, N.B.2    Raissdana, S.S.3
  • 55
    • 55049114476 scopus 로고    scopus 로고
    • Tumor necrosis factoralpha modulates survival, proliferation, and neuronal differentiation in neonatal subven tricular zone cell cultures
    • Bernardino L, Agasse F, Silva B, Ferreira R, Grade S and Malva JO. Tumor necrosis factoralpha modulates survival, proliferation, and neuronal differentiation in neonatal subven tricular zone cell cultures. Stem Cells 2008; 26: 2361-2371.
    • (2008) Stem Cells , vol.26 , pp. 2361-2371
    • Bernardino, L.1    Agasse, F.2    Silva, B.3    Ferreira, R.4    Grade, S.5    Malva, J.O.6
  • 58
    • 30044434850 scopus 로고    scopus 로고
    • Microglia activated by IL-4 or IFN-gamma differentially induce neurogenesis and oligodendrogenesis from adult stem/progenitor cells
    • Butovsky O, Ziv Y, Schwartz A, Landa G, Talpalar AE, Pluchino S, Martino G and Schwartz M. Microglia activated by IL-4 or IFN-gamma differentially induce neurogenesis and oligodendrogenesis from adult stem/progenitor cells. Mol Cell Neurosci 2006; 31: 149-160.
    • (2006) Mol Cell Neurosci , vol.31 , pp. 149-160
    • Butovsky, O.1    Ziv, Y.2    Schwartz, A.3    Landa, G.4    Talpalar, A.E.5    Pluchino, S.6    Martino, G.7    Schwartz, M.8
  • 59
    • 49849085127 scopus 로고    scopus 로고
    • Non-cell-autonomous effects of presenilin 1 variants on enrichment-mediated hippocampal progenitor cell proliferation and differentiation
    • Choi SH, Veeraraghavalu K, Lazarov O, Marler S, Ransohoff RM, Ramirez JM and Sisodia SS. Non-cell-autonomous effects of presenilin 1 variants on enrichment-mediated hippocampal progenitor cell proliferation and differentiation. Neuron 2008; 59: 568-580.
    • (2008) Neuron , vol.59 , pp. 568-580
    • Choi, S.H.1    Veeraraghavalu, K.2    Lazarov, O.3    Marler, S.4    Ransohoff, R.M.5    Ramirez, J.M.6    Sisodia, S.S.7
  • 64
    • 0035912198 scopus 로고    scopus 로고
    • Pathways to neuronal injury and apoptosis in HIV-associated dementia
    • Kaul M, Garden GA and Lipton SA. Pathways to neuronal injury and apoptosis in HIV-associated dementia. Nature 2001; 410: 988-994.
    • (2001) Nature , vol.410 , pp. 988-994
    • Kaul, M.1    Garden, G.A.2    Lipton, S.A.3
  • 65
    • 0033529303 scopus 로고    scopus 로고
    • Chemokines and activated macrophages in HIV gp120-induced neuronal apoptosis
    • Kaul M and Lipton SA. Chemokines and activated macrophages in HIV gp120-induced neuronal apoptosis. Proc Natl Acad Sci U S A 1999; 96: 8212-8216.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 8212-8216
    • Kaul, M.1    Lipton, S.A.2
  • 66
    • 0034628624 scopus 로고    scopus 로고
    • HIV type 1-induced inhibition of CD45 tyrosine phosphatase activity correlates with disease progression and apoptosis, but not with anti-CD3-induced T cell proliferation
    • Giovannetti A, Pierdominici M, Mazzetta F, Mazzone AM, Ricci G, Prozzo A, Pandolfi F, Paganelli R and Aiuti F. HIV type 1-induced inhibition of CD45 tyrosine phosphatase activity correlates with disease progression and apoptosis, but not with anti-CD3-induced T cell proliferation. AIDS Res Hum Retroviruses 2000; 16: 211-219.
    • (2000) AIDS Res Hum Retroviruses , vol.16 , pp. 211-219
    • Giovannetti, A.1    Pierdominici, M.2    Mazzetta, F.3    Mazzone, A.M.4    Ricci, G.5    Prozzo, A.6    Pandolfi, F.7    Paganelli, R.8    Aiuti, F.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.