-
1
-
-
39549097791
-
Kava consumption and its health effects
-
Gounder, R. (2006) Kava consumption and its health effects. Pacific Health Dialogue 13, 131-135.
-
(2006)
Pacific Health Dialogue
, vol.13
, pp. 131-135
-
-
Gounder, R.1
-
2
-
-
79956264661
-
Neurocognitive effects of kava (Piper methysticum): A systematic review
-
LaPorte, E., Sarris, J., Stough, C., and Scholey, A. (2011) Neurocognitive effects of kava (Piper methysticum): a systematic review. Hum. Psychopharmacol. 26, 102-111.
-
(2011)
Hum. Psychopharmacol.
, vol.26
, pp. 102-111
-
-
LaPorte, E.1
Sarris, J.2
Stough, C.3
Scholey, A.4
-
3
-
-
60549099731
-
St. John's wort and Kava in treating major depressive disorder with comorbid anxiety: A randomised double-blind placebo-controlled pilot trial
-
Sarris, J., Kavanagh, D. J., Deed, G., and Bone, K. M. (2009) St. John's wort and Kava in treating major depressive disorder with comorbid anxiety: a randomised double-blind placebo-controlled pilot trial. Hum. Psychopharmacol. 24, 41-48.
-
(2009)
Hum. Psychopharmacol.
, vol.24
, pp. 41-48
-
-
Sarris, J.1
Kavanagh, D.J.2
Deed, G.3
Bone, K.M.4
-
4
-
-
67651005824
-
The Kava Anxiety Depression Spectrum Study (KADSS): A randomized, placebo-controlled crossover trial using an aqueous extract of Piper methysticum
-
Sarris, J., Kavanagh, D. J., Byrne, G., Bone, K. M., Adams, J., and Deed, G. (2009) The Kava Anxiety Depression Spectrum Study (KADSS): a randomized, placebo-controlled crossover trial using an aqueous extract of Piper methysticum. Psychopharmacology (Berl.) 205, 399-407.
-
(2009)
Psychopharmacology (Berl.)
, vol.205
, pp. 399-407
-
-
Sarris, J.1
Kavanagh, D.J.2
Byrne, G.3
Bone, K.M.4
Adams, J.5
Deed, G.6
-
5
-
-
0033971030
-
Efficacy of kava extract for treating anxiety: Systematic review and meta-analysis
-
Pittler, M. H., and Ernst, E. (2000) Efficacy of kava extract for treating anxiety: systematic review and meta-analysis. J. Clin. Psychopharmacol. 20, 84-89.
-
(2000)
J. Clin. Psychopharmacol.
, vol.20
, pp. 84-89
-
-
Pittler, M.H.1
Ernst, E.2
-
6
-
-
70350766713
-
Kava hepatotoxicity: Regulatory data selection and causality assessment
-
Teschke, R., and Wolff, A. (2009) Kava hepatotoxicity: regulatory data selection and causality assessment. Dig. Liver Dis. 41, 891-901.
-
(2009)
Dig. Liver Dis.
, vol.41
, pp. 891-901
-
-
Teschke, R.1
Wolff, A.2
-
7
-
-
84874931332
-
Contaminant hepatotoxins as culprits for kava hepatotoxicity-fact or fiction?
-
Teschke, R., Sarris, J., and Lebot, V. (2013) Contaminant hepatotoxins as culprits for kava hepatotoxicity-fact or fiction? Phytother. Res. 27, 472-474.
-
(2013)
Phytother. Res.
, vol.27
, pp. 472-474
-
-
Teschke, R.1
Sarris, J.2
Lebot, V.3
-
8
-
-
84908129229
-
German court repeals the withdrawal of marketing authorisation of kava-containing medicinal products
-
Carreño, I., Laurenza, E., Martelloni, A., Salas, B., Simões, B. G., and Vergona, P. R. (2014) German court repeals the withdrawal of marketing authorisation of kava-containing medicinal products. Trade Perspectives 13, 2-5.
-
(2014)
Trade Perspectives
, vol.13
, pp. 2-5
-
-
Carreño, I.1
Laurenza, E.2
Martelloni, A.3
Salas, B.4
Simões, B.G.5
Vergona, P.R.6
-
9
-
-
0038249051
-
Toxicity of kava pyrones, drug safety and precautions - A case study
-
Schulze, J., Raasch, W., and Siegers, C. P. (2003) Toxicity of kava pyrones, drug safety and precautions - a case study. Phytomedicine 10, 68-73.
-
(2003)
Phytomedicine
, vol.10
, pp. 68-73
-
-
Schulze, J.1
Raasch, W.2
Siegers, C.P.3
-
10
-
-
1842431946
-
Kava Hepatotoxicity: Are we any closer to the truth?
-
Anke, J., and Ramzan, I. (2004) Kava Hepatotoxicity: Are we any closer to the truth? Planta Med. 70, 193-196.
-
(2004)
Planta Med.
, vol.70
, pp. 193-196
-
-
Anke, J.1
Ramzan, I.2
-
11
-
-
84890482601
-
Detection of flavokavins (A, B, C) in cultivars of kava (Piper methysticum) using high performance thin layer chromatography (HPTLC)
-
Lebot, V., Do, T. K., and Legendre, L. (2014) Detection of flavokavins (A, B, C) in cultivars of kava (Piper methysticum) using high performance thin layer chromatography (HPTLC). Food Chem. 151, 554-560.
-
(2014)
Food Chem.
, vol.151
, pp. 554-560
-
-
Lebot, V.1
Do, T.K.2
Legendre, L.3
-
12
-
-
69949109902
-
Identification of methysticin as a potent and non-toxic NF-kappaB inhibitor from kava, potentially responsible for kava's chemopreventive activity
-
Shaik, A. A., Hermanson, D. L., and Xing, C. (2009) Identification of methysticin as a potent and non-toxic NF-kappaB inhibitor from kava, potentially responsible for kava's chemopreventive activity. Bioorg. Med. Chem. Lett. 19, 5732-5736.
-
(2009)
Bioorg. Med. Chem. Lett.
, vol.19
, pp. 5732-5736
-
-
Shaik, A.A.1
Hermanson, D.L.2
Xing, C.3
-
13
-
-
84892385065
-
Kava Blocks 4-(Methylnitrosamino)-1-(3-pyridyl)-1-Butanone-Induced Lung Tumorigenesis in Association with Reducing O6-methylguanine DNA Adduct in A/J Mice
-
Leitzman, P., Narayanapillai, S. C., Balbo, S., Zhou, B., Upadhyaya, P., Shaik, A. A., O'Sullivan, M. G., Hecht, S. S., Lu, J., and Xing, C. (2014) Kava Blocks 4-(Methylnitrosamino)-1-(3-pyridyl)-1-Butanone-Induced Lung Tumorigenesis in Association with Reducing O6-methylguanine DNA Adduct in A/J Mice. Cancer Prev. Res. (Phila.) 7, 86-96.
-
(2014)
Cancer Prev. Res. (Phila.)
, vol.7
, pp. 86-96
-
-
Leitzman, P.1
Narayanapillai, S.C.2
Balbo, S.3
Zhou, B.4
Upadhyaya, P.5
Shaik, A.A.6
O'Sullivan, M.G.7
Hecht, S.S.8
Lu, J.9
Xing, C.10
-
15
-
-
56349138698
-
Kava hepatotoxicity: A clinical survey and critical analysis of 26 suspected cases
-
Teschke, R., Schwarzenboeck, A., and Hennermann, K. H. (2008) Kava hepatotoxicity: a clinical survey and critical analysis of 26 suspected cases. Eur. J. Gastroenterol. Hepatol. 20, 1182-1193.
-
(2008)
Eur. J. Gastroenterol. Hepatol.
, vol.20
, pp. 1182-1193
-
-
Teschke, R.1
Schwarzenboeck, A.2
Hennermann, K.H.3
-
16
-
-
0034327338
-
The correlation between cancer incidence and kava consumption
-
Steiner, G. G. (2000) The correlation between cancer incidence and kava consumption. Hawaii Med. J. 59, 420-422.
-
(2000)
Hawaii Med. J.
, vol.59
, pp. 420-422
-
-
Steiner, G.G.1
-
17
-
-
79959950118
-
Lung tumorigenesis suppressing effects of a commercial kava extract and its selected compounds in A/J mice
-
Johnson, T. E., Hermanson, D., Wang, L., Kassie, F., Upadhyaya, P., O'Sullivan, M. G., Hecht, S. S., Lu, J., and Xing, C. (2011) Lung tumorigenesis suppressing effects of a commercial kava extract and its selected compounds in A/J mice. Am. J. Chin. Med. 39, 727-742.
-
(2011)
Am. J. Chin. Med.
, vol.39
, pp. 727-742
-
-
Johnson, T.E.1
Hermanson, D.2
Wang, L.3
Kassie, F.4
Upadhyaya, P.5
O'Sullivan, M.G.6
Hecht, S.S.7
Lu, J.8
Xing, C.9
-
18
-
-
61749084029
-
Chemopreventive effect of kava on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone plus benzo[a]pyrene-induced lung tumorigenesis in A/J mice
-
Johnson, T. E., Kassie, F., O'Sullivan, M. G., Negia, M., Hanson, T. E., Upadhyaya, P., Ruvolo, P. P., Hecht, S. S., and Xing, C. (2008) Chemopreventive effect of kava on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone plus benzo[a]pyrene-induced lung tumorigenesis in A/J mice. Cancer Prev. Res. (Phila.) 1, 430-438.
-
(2008)
Cancer Prev. Res. (Phila.)
, vol.1
, pp. 430-438
-
-
Johnson, T.E.1
Kassie, F.2
O'Sullivan, M.G.3
Negia, M.4
Hanson, T.E.5
Upadhyaya, P.6
Ruvolo, P.P.7
Hecht, S.S.8
Xing, C.9
-
19
-
-
84865248458
-
Reduction in colon cancer risk by consumption of kava or kava fractions in carcinogen-treated rats
-
Triolet, J., Shaik, A. A., Gallaher, D. D., O'Sullivan, M. G., and Xing, C. (2012) Reduction in colon cancer risk by consumption of kava or kava fractions in carcinogen-treated rats. Nutr. Cancer 64, 838-846.
-
(2012)
Nutr. Cancer
, vol.64
, pp. 838-846
-
-
Triolet, J.1
Shaik, A.A.2
Gallaher, D.D.3
O'Sullivan, M.G.4
Xing, C.5
-
20
-
-
17144400791
-
Flavokawain A, a Novel Chalcone from Kava Extract, Induces Apoptosis in Bladder Cancer Cells by Involvement of Bax Protein-Dependent and Mitochondria-Dependent Apoptotic Pathway and Suppresses Tumor Growth in Mice
-
Zi, X., and Simoneau, A. R. (2005) Flavokawain A, a Novel Chalcone from Kava Extract, Induces Apoptosis in Bladder Cancer Cells by Involvement of Bax Protein-Dependent and Mitochondria-Dependent Apoptotic Pathway and Suppresses Tumor Growth in Mice. Cancer Res. 65, 3479-3486.
-
(2005)
Cancer Res.
, vol.65
, pp. 3479-3486
-
-
Zi, X.1
Simoneau, A.R.2
-
21
-
-
84908124795
-
Dihydromethysticin (DHM) from kava blocks tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung tumorigenesis and differentially reduces DNA damage in A/J mice
-
Narayanapillai, S. C., Balbo, S., Leitzman, P., Grill, A. E., Upadhyaya, P., Shaik, A. A., Zhou, B., O'Sullivan, M. G., Peterson, L., Lu, J., Hecht, S. S., and Xing, C. (2014) Dihydromethysticin (DHM) from kava blocks tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung tumorigenesis and differentially reduces DNA damage in A/J mice. Carcinogenesis,
-
(2014)
Carcinogenesis
-
-
Narayanapillai, S.C.1
Balbo, S.2
Leitzman, P.3
Grill, A.E.4
Upadhyaya, P.5
Shaik, A.A.6
Zhou, B.7
O'Sullivan, M.G.8
Peterson, L.9
Lu, J.10
Hecht, S.S.11
Xing, C.12
-
22
-
-
84909619250
-
Measuring the chemical and cytotoxic variability of commercially available kava
-
Martin, A. C. J. E., Xing, C., and Hegeman, A. D. (2014) Measuring the chemical and cytotoxic variability of commercially available kava. PLoS One,.
-
(2014)
PLoS One
-
-
Martin, A.C.J.E.1
Xing, C.2
Hegeman, A.D.3
-
23
-
-
84863617682
-
Toxicology and carcinogenesis studies of kava kava extract (CAS No. 9000-38-8) in F344/N rats and B6C3F1 mice (Gavage Studies)
-
National Toxicology Program. (2012) Toxicology and carcinogenesis studies of kava kava extract (CAS No. 9000-38-8) in F344/N rats and B6C3F1 mice (Gavage Studies). Natl. Toxicol. Program Tech. Rep. Ser., 1-186.
-
(2012)
Natl. Toxicol. Program Tech. Rep. Ser.
, pp. 1-186
-
-
National Toxicology Program1
-
24
-
-
79955701682
-
Kava extract, an herbal alternative for anxiety relief, potentiates acetaminophen-induced cytotoxicity in rat hepatic cells
-
Yang, X., and Salminen, W. F. (2011) Kava extract, an herbal alternative for anxiety relief, potentiates acetaminophen-induced cytotoxicity in rat hepatic cells. Phytomedicine 18, 592-600.
-
(2011)
Phytomedicine
, vol.18
, pp. 592-600
-
-
Yang, X.1
Salminen, W.F.2
-
25
-
-
33646500546
-
In vitro cytotoxicity of nonpolar constituents from different parts of kava plant (Piper methysticum)
-
Jhoo, J. W., Freeman, J. P., Heinze, T. M., Moody, J. D., Schnackenberg, L. K., Beger, R. D., Dragull, K., Tang, C. S., and Ang, C. Y. (2006) In vitro cytotoxicity of nonpolar constituents from different parts of kava plant (Piper methysticum). J. Agric. Food Chem. 54, 3157-3162.
-
(2006)
J. Agric. Food Chem.
, vol.54
, pp. 3157-3162
-
-
Jhoo, J.W.1
Freeman, J.P.2
Heinze, T.M.3
Moody, J.D.4
Schnackenberg, L.K.5
Beger, R.D.6
Dragull, K.7
Tang, C.S.8
Ang, C.Y.9
-
26
-
-
34247135372
-
Kava feeding in rats does not cause liver injury nor enhance galactosamineinduced hepatitis
-
DiSilvestro, R. A., Zhang, W., and DiSilvestro, D. J. (2007) Kava feeding in rats does not cause liver injury nor enhance galactosamineinduced hepatitis. Food Chem. Toxicol. 45, 1293-1300.
-
(2007)
Food Chem. Toxicol.
, vol.45
, pp. 1293-1300
-
-
DiSilvestro, R.A.1
Zhang, W.2
DiSilvestro, D.J.3
-
27
-
-
58149512737
-
Analysis of gene expression changes of drug metabolizing enzymes in the livers of F344 rats following oral treatment with kava extract
-
Guo, L., Li, Q., Xia, Q., Dial, S., Chan, P. C., and Fu, P. (2009) Analysis of gene expression changes of drug metabolizing enzymes in the livers of F344 rats following oral treatment with kava extract. Food Chem. Toxicol. 47, 433-442.
-
(2009)
Food Chem. Toxicol.
, vol.47
, pp. 433-442
-
-
Guo, L.1
Li, Q.2
Xia, Q.3
Dial, S.4
Chan, P.C.5
Fu, P.6
-
28
-
-
74649085160
-
Gene expression profiling in male B6C3F1 mouse livers exposed to kava identifies - Changes in drug metabolizing genes and potential mechanisms linked to kava toxicity
-
Guo, L., Shi, Q., Dial, S., Xia, Q., Mei, N., Li, Q. Z., Chan, P. C., and Fu, P. (2010) Gene expression profiling in male B6C3F1 mouse livers exposed to kava identifies - changes in drug metabolizing genes and potential mechanisms linked to kava toxicity. Food Chem. Toxicol. 48, 686-696.
-
(2010)
Food Chem. Toxicol.
, vol.48
, pp. 686-696
-
-
Guo, L.1
Shi, Q.2
Dial, S.3
Xia, Q.4
Mei, N.5
Li, Q.Z.6
Chan, P.C.7
Fu, P.8
-
29
-
-
33747131402
-
Safety of ethanolic kava extract: Results of a study of chronic toxicity in rats
-
Sorrentino, L., Capasso, A., and Schmidt, M. (2006) Safety of ethanolic kava extract: Results of a study of chronic toxicity in rats. Phytomedicine 13, 542-549.
-
(2006)
Phytomedicine
, vol.13
, pp. 542-549
-
-
Sorrentino, L.1
Capasso, A.2
Schmidt, M.3
-
30
-
-
78349302551
-
Flavokawain B, the hepatotoxic constituent from kava root, induces GSH-sensitive oxidative stress through modulation of IKK/NF-kappa B and MAPK signaling pathways
-
Zhou, P., Gross, S., Liu, J. H., Yu, B. Y., Feng, L. L., Nolta, J., Sharma, V., Piwnica-Worms, D., and Qiu, S. X. (2010) Flavokawain B, the hepatotoxic constituent from kava root, induces GSH-sensitive oxidative stress through modulation of IKK/NF-kappa B and MAPK signaling pathways. FASEB J. 24, 4722-4732.
-
(2010)
FASEB J.
, vol.24
, pp. 4722-4732
-
-
Zhou, P.1
Gross, S.2
Liu, J.H.3
Yu, B.Y.4
Feng, L.L.5
Nolta, J.6
Sharma, V.7
Piwnica-Worms, D.8
Qiu, S.X.9
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