SIRT6 promotes COX-2 expression and acts as an oncogene in skin cancer

Cancer Research

Volumn 74, Issue 20, 2014, Pages 5925-5933

  Ming, Mei ^a   Han, Weinong ^a   Zhao, Baozhong ^a   Sundaresan, Nagalingam R ^a,b   Deng, Chu Xia ^c   Gupta, Mahesh P ^a   He, Yu Ying ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b INDIAN INSTITUTE OF SCIENCE   (India)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOOXYGENASE 2; PROTEIN KINASE B; SIRTUIN 6; ADENYLATE KINASE; PTGS2 PROTEIN, HUMAN; SIRT6 PROTEIN, HUMAN; SIRTUIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; EPIDERMIS; EPIDERMIS HYPERPLASIA; FEMALE; GENE DELETION; GENE FUNCTION; HUMAN; HUMAN CELL; IN VIVO STUDY; KERATINOCYTE; MOUSE; NONHUMAN; ONCOGENE; PROTEIN EXPRESSION; PROTEIN STABILITY; RADIATION EXPOSURE; SIGNAL TRANSDUCTION; SIRT6 GENE; SKIN CARCINOGENESIS; SQUAMOUS CELL CARCINOMA; ULTRAVIOLET B RADIATION; UPREGULATION; ANIMAL; C57BL MOUSE; CARCINOGENESIS; CELL CULTURE; ENZYME INDUCTION; ENZYMOLOGY; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETICS; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PHYSIOLOGY; RADIATION RESPONSE; RNA STABILITY; SKIN TUMOR; ULTRAVIOLET RADIATION;

ADENYLATE KINASE; ANIMALS; CARCINOGENESIS; CARCINOMA, SQUAMOUS CELL; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; CYCLOOXYGENASE 2; ENZYME INDUCTION; EPIDERMIS; GENE EXPRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICE, INBRED C57BL; MICE, KNOCKOUT; ONCOGENES; PROTO-ONCOGENE PROTEINS C-AKT; RNA STABILITY; SIRTUINS; SKIN NEOPLASMS; ULTRAVIOLET RAYS;

EID: 84908128033     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-14-1308     Document Type: Article

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