A novel tumor necrosis factor-mediated mechanism of direct epithelial sodium channel activation

American Journal of Respiratory and Critical Care Medicine

Volumn 190, Issue 5, 2014, Pages 522-532

  Czikora, István ^a   Alli, Abdel ^b   Bao, Hui Fang ^b   Kaftan, David ^c   Sridhar, Supriya ^a   Apell, Hans Jürgen ^d   Gorshkov, Boris ^a   White, Richard ^a   Zimmermann, Astrid ^d   Wendel, Albrecht ^d   Pauly Evers, Meike ^e   Hamacher, Jürg ^d,f   Garcia Gabay, Irène ^g   Fischer, Bernhard ^h   Verin, Alexander ^a   Bagi, Zsolt ^a   Pittet, Jean Francois ⁱ   Shabbir, Waheed ^j   Lemmens Gruber, Rosa ^j   Chakraborty, Trinad ^k   Lazrak, Ahmed ⁱ   Matthay, Michael A ^l   Eaton, Douglas C ^b   Lucas, Rudolf ^a,m   more..

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b EMORY UNIVERSITY   (United States)

^c UNIVERSITY OF SOUTH BOHEMIA   (Czech Republic)

^d UNIVERSITY OF KONSTANZ   (Germany)

^e F HOFFMANN LA ROCHE LTD   (Switzerland)

^f SAARLAND UNIVERSITY   (Germany)

^g UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^h Apeptico   (Austria)

ⁱ UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^j UNIVERSITY OF VIENNA   (Austria)

^k JUSTUS LIEBIG UNIVERSITY GIESSEN   (Germany)

^l UNIVERSITY OF CALIFORNIA   (United States)

^m AUGUSTA UNIVERSITY   (United States)

more..

Author keywords

Epithelial sodium channel; Pneumonia; Protein kinase C ; Pulmonary edema; Tumor necrosis factor

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); AMILORIDE; EPITHELIAL SODIUM CHANNEL; INTERLEUKIN 6; LECTIN LIKE DOMAIN OF TUMOR NECROSIS FACTOR; MARCKS PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PEPTIDE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PNEUMOLYSIN; PROTEIN KINASE C ALPHA; UNCLASSIFIED DRUG; AP301 PEPTIDE; BACTERIAL PROTEIN; CYCLOPEPTIDE; EPITHELIAL SODIUM CHANNEL STIMULATING AGENT; PLY PROTEIN, STREPTOCOCCUS PNEUMONIAE; STREPTOLYSIN; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ALPHA;

ACUTE LUNG INJURY; ALKALINITY; ALPHA CHAIN; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BETA CHAIN; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CELL INFILTRATION; DOWN REGULATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE COMPLEX; ENZYME SUBUNIT; FEMALE; GENE ACTIVATION; GENE ACTIVITY; GENE MUTATION; IN VITRO STUDY; IN VIVO STUDY; LUNG DIFFUSION; LUNG EDEMA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN GLYCOSYLATION; PROTEIN TARGETING; SODIUM TRANSPORT; UPREGULATION; ANIMAL; C57BL MOUSE; CHEMISTRY; LUNG ALVEOLUS; METABOLISM; MICROBIOLOGY; MUTANT MOUSE STRAIN; PNEUMONIA; PROTEIN KINASE C-Α;

EPITHELIAL SODIUM CHANNEL; PNEUMONIA; PROTEIN KINASE C-Α; PULMONARY EDEMA; TUMOR NECROSIS FACTOR;

ANIMALS; BACTERIAL PROTEINS; EPITHELIAL SODIUM CHANNEL AGONISTS; EPITHELIAL SODIUM CHANNELS; FEMALE; MALE; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; PEPTIDES, CYCLIC; PULMONARY ALVEOLI; PULMONARY EDEMA; STREPTOLYSINS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84908125905     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201405-0833OC     Document Type: Article

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