Vascular dysfunction induced in offspring by maternal dietary fat involves altered arterial polyunsaturated fatty acid biosynthesis

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  Kelsall, Christopher J ^a   Hoile, Samuel P ^a   Irvine, Nicola A ^a   Masoodi, Mojgan ^b   Torrens, Christopher ^a   Lillycrop, Karen A ^c   Calder, Philip C ^a   Clough, Geraldine F ^a   Hanson, Mark A ^a   Burdge, Graham C ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b MRC HUMAN NUTRITION RESEARCH   (United Kingdom)

^c UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL COENZYME A DESATURASE 1; FISH OIL; ICOSANOID; LINOLEOYL COENZYME A DESATURASE; MESSENGER RNA; POLYUNSATURATED FATTY ACID; SATURATED FATTY ACID; SOYBEAN OIL; TRANS FATTY ACID; ACETYLCHOLINE; ACYL COENZYME A DESATURASE; ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 1 ADRENERGIC RECEPTOR STIMULATING AGENT; DELTA 6 DESATURASE, RAT; DELTA 6-DESATURASE, RAT; MUSCARINIC AGENT; MUSCARINIC RECEPTOR; PHENYLEPHRINE; UNSATURATED FATTY ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTERY CONSTRICTION; ARTERY DILATATION; ARTERY MUSCLE; ARTICLE; CONTROLLED STUDY; DNA METHYLATION; ENZYME INHIBITION; FADS1 GENE; FADS2 GENE; FAT INTAKE; FATTY ACID SYNTHESIS; FEMALE; GENE; GENE EXPRESSION; GENE LOCUS; GENETIC TRANSCRIPTION; HUMAN; HUMAN TISSUE; LACTATION; MALE; MATERNAL NUTRITION; MESENTERIC ARTERY; NONHUMAN; PREGNANCY; PROGENY; RAT; TRANSCRIPTION INITIATION SITE; VASCULAR DISEASE; VASCULAR ENDOTHELIUM; ANIMAL; ARTERY; BIOSYNTHESIS; BLOOD; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOTHER; PATHOPHYSIOLOGY; THORACIC AORTA; VASOCONSTRICTION; VASODILATATION; WISTAR RAT;

GLYCINE MAX; RATTUS;

ACETYLCHOLINE; ADRENERGIC ALPHA-1 RECEPTOR AGONISTS; ANIMALS; AORTA, THORACIC; ARTERIES; DIETARY FATS; FATTY ACIDS, UNSATURATED; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; MALE; MESENTERIC ARTERIES; MOTHERS; MUSCARINIC AGONISTS; PHENYLEPHRINE; PREGNANCY; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, ALPHA-1; RECEPTORS, MUSCARINIC; RNA, MESSENGER; STEAROYL-COA DESATURASE; VASOCONSTRICTION; VASODILATION;

EID: 84859221006     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0034492     Document Type: Article

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