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Volumn 20, Issue 10, 2014, Pages 551-558

Cyclic dipeptides: From bugs to brain

Author keywords

Diketopiperazines; Neurodegeneration; Neuroinflammation; Neuroprotection; Quorum sensing

Indexed keywords

CENTRAL NERVOUS SYSTEM AGENTS; CYCLO(HIS-PRO); DIPEPTIDE; ORGANIC CATION TRANSPORTER; UNCLASSIFIED DRUG; CYCLOPEPTIDE; HISTIDYL-PROLINE DIKETOPIPERAZINE; PIPERAZINE DERIVATIVE;

EID: 84908122041     PISSN: 14714914     EISSN: 1471499X     Source Type: Journal    
DOI: 10.1016/j.molmed.2014.08.003     Document Type: Review
Times cited : (94)

References (78)
  • 1
    • 0035675837 scopus 로고    scopus 로고
    • Regulation of gene expression by cell-to-cell communication: acyl-homoserine lactone quorum sensing
    • Fuqua C., et al. Regulation of gene expression by cell-to-cell communication: acyl-homoserine lactone quorum sensing. Annu. Rev. Genet. 2001, 35:439-468.
    • (2001) Annu. Rev. Genet. , vol.35 , pp. 439-468
    • Fuqua, C.1
  • 2
    • 8744303083 scopus 로고    scopus 로고
    • Is autoinducer-2 a universal signal for interspecies communication: a comparative genomic and phylogenetic analysis of the synthesis and signal transduction pathways
    • Sun J., et al. Is autoinducer-2 a universal signal for interspecies communication: a comparative genomic and phylogenetic analysis of the synthesis and signal transduction pathways. BMC Evol. Biol. 2004, 4:36.
    • (2004) BMC Evol. Biol. , vol.4 , pp. 36
    • Sun, J.1
  • 3
    • 79955553268 scopus 로고    scopus 로고
    • Transkingdom signaling based on bacterial cyclodipeptides with auxin activity in plants
    • Ortiz-Castro R., et al. Transkingdom signaling based on bacterial cyclodipeptides with auxin activity in plants. Proc. Natl Acad. Sci. U.S.A. 2011, 108:7253-7258.
    • (2011) Proc. Natl Acad. Sci. U.S.A. , vol.108 , pp. 7253-7258
    • Ortiz-Castro, R.1
  • 4
    • 38349127277 scopus 로고    scopus 로고
    • Inter-kingdom signalling: communication between bacteria and their hosts
    • Hughes D.T., Sperandio V. Inter-kingdom signalling: communication between bacteria and their hosts. Nat. Rev. Microbiol. 2008, 6:111-120.
    • (2008) Nat. Rev. Microbiol. , vol.6 , pp. 111-120
    • Hughes, D.T.1    Sperandio, V.2
  • 5
    • 0041806524 scopus 로고    scopus 로고
    • Bacteria-host communication: the language of hormones
    • Sperandio V., et al. Bacteria-host communication: the language of hormones. Proc. Natl Acad. Sci. U.S.A. 2003, 100:8951-8956.
    • (2003) Proc. Natl Acad. Sci. U.S.A. , vol.100 , pp. 8951-8956
    • Sperandio, V.1
  • 6
    • 0018573528 scopus 로고
    • Bacterial bioluminescence: its control and ecological significance
    • Nealson K.H., Hastings J.W. Bacterial bioluminescence: its control and ecological significance. Microbiol. Rev. 1979, 43:496-518.
    • (1979) Microbiol. Rev. , vol.43 , pp. 496-518
    • Nealson, K.H.1    Hastings, J.W.2
  • 7
    • 84887256074 scopus 로고    scopus 로고
    • Evaluation of an I-box wind tunnel model for assessment of behavioral responses of blow flies
    • Moophayak K., et al. Evaluation of an I-box wind tunnel model for assessment of behavioral responses of blow flies. Parasitol. Res. 2013, 112:3789-3798.
    • (2013) Parasitol. Res. , vol.112 , pp. 3789-3798
    • Moophayak, K.1
  • 8
    • 84887034499 scopus 로고    scopus 로고
    • A quorum-sensing inhibitor blocks Pseudomonas aeruginosa virulence and biofilm formation
    • O'Loughlin C.T., et al. A quorum-sensing inhibitor blocks Pseudomonas aeruginosa virulence and biofilm formation. Proc. Natl. Acad. Sci. U.S.A. 2013, 110:17981-17986.
    • (2013) Proc. Natl. Acad. Sci. U.S.A. , vol.110 , pp. 17981-17986
    • O'Loughlin, C.T.1
  • 9
    • 69949145990 scopus 로고    scopus 로고
    • Quorum sensing differentially regulates Pseudomonas aeruginosa type VI secretion locus I and homologous loci II and III, which are required for pathogenesis
    • Lesic B., et al. Quorum sensing differentially regulates Pseudomonas aeruginosa type VI secretion locus I and homologous loci II and III, which are required for pathogenesis. Microbiology 2009, 155:2845-2855.
    • (2009) Microbiology , vol.155 , pp. 2845-2855
    • Lesic, B.1
  • 10
    • 77956767387 scopus 로고    scopus 로고
    • Regulation of motility in Erwinia carotovora subsp. carotovora: quorum-sensing signal controls FlhDC, the global regulator of flagellar and exoprotein genes, by modulating the production of RsmA, an RNA-binding protein
    • Chatterjee A., et al. Regulation of motility in Erwinia carotovora subsp. carotovora: quorum-sensing signal controls FlhDC, the global regulator of flagellar and exoprotein genes, by modulating the production of RsmA, an RNA-binding protein. Mol. Plant Microbe Interact. 2010, 23:1316-1323.
    • (2010) Mol. Plant Microbe Interact. , vol.23 , pp. 1316-1323
    • Chatterjee, A.1
  • 11
    • 84901019334 scopus 로고    scopus 로고
    • Functions and regulation of quorum-sensing in Agrobacterium tumefaciens
    • Lang J., Faure D. Functions and regulation of quorum-sensing in Agrobacterium tumefaciens. Front. Plant Sci. 2014, 5:14.
    • (2014) Front. Plant Sci. , vol.5 , pp. 14
    • Lang, J.1    Faure, D.2
  • 12
    • 84862276328 scopus 로고    scopus 로고
    • Structure, function and diversity of the healthy human microbiome
    • Human Microbiome Project Consortium Structure, function and diversity of the healthy human microbiome. Nature 2012, 486:207-214.
    • (2012) Nature , vol.486 , pp. 207-214
  • 13
    • 84871444274 scopus 로고    scopus 로고
    • Dissection of quorum-sensing genes in Burkholderia glumae reveals non-canonical regulation and the new regulatory gene tofM for toxoflavin production
    • Chen R., et al. Dissection of quorum-sensing genes in Burkholderia glumae reveals non-canonical regulation and the new regulatory gene tofM for toxoflavin production. PLoS ONE 2012, 7:e52150.
    • (2012) PLoS ONE , vol.7 , pp. e52150
    • Chen, R.1
  • 14
    • 0037203773 scopus 로고    scopus 로고
    • Structural identification of a bacterial quorum-sensing signal containing boron
    • Chen X., et al. Structural identification of a bacterial quorum-sensing signal containing boron. Nature 2002, 415:545-549.
    • (2002) Nature , vol.415 , pp. 545-549
    • Chen, X.1
  • 15
    • 79952769629 scopus 로고    scopus 로고
    • Lactobacillus reuteri-produced cyclic dipeptides quench agr-mediated expression of toxic shock syndrome toxin-1 in staphylococci
    • Li J., et al. Lactobacillus reuteri-produced cyclic dipeptides quench agr-mediated expression of toxic shock syndrome toxin-1 in staphylococci. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:3360-3365.
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 3360-3365
    • Li, J.1
  • 16
    • 84921666045 scopus 로고    scopus 로고
    • Interspecies competition triggers virulence and mutability in Candida albicans-Pseudomonas aeruginosa mixed biofilms
    • Trejo-Hernández A., et al. Interspecies competition triggers virulence and mutability in Candida albicans-Pseudomonas aeruginosa mixed biofilms. ISME J. 2014, 10.1038/ismej.2014.53.
    • (2014) ISME J.
    • Trejo-Hernández, A.1
  • 17
    • 84867946014 scopus 로고    scopus 로고
    • Quorum sensing in the probiotic bacterium Escherichia coli Nissle 1917 (Mutaflor) - evidence that furanosyl borate diester (AI-2) is influencing the cytokine expression in the DSS colitis mouse model
    • Jacobi C.A. Quorum sensing in the probiotic bacterium Escherichia coli Nissle 1917 (Mutaflor) - evidence that furanosyl borate diester (AI-2) is influencing the cytokine expression in the DSS colitis mouse model. Gut Pathog. 2012, 4:8.
    • (2012) Gut Pathog. , vol.4 , pp. 8
    • Jacobi, C.A.1
  • 18
    • 36849039449 scopus 로고    scopus 로고
    • The major Vibrio cholerae autoinducer and its role in virulence factor production
    • Higgins D.A., et al. The major Vibrio cholerae autoinducer and its role in virulence factor production. Nature 2007, 450:883-886.
    • (2007) Nature , vol.450 , pp. 883-886
    • Higgins, D.A.1
  • 19
    • 1942469383 scopus 로고    scopus 로고
    • The evolutionary history of quorum-sensing systems in bacteria
    • Lerat E., Moran N.A. The evolutionary history of quorum-sensing systems in bacteria. Mol. Biol. Evol. 2004, 21:903-913.
    • (2004) Mol. Biol. Evol. , vol.21 , pp. 903-913
    • Lerat, E.1    Moran, N.A.2
  • 20
    • 84882745417 scopus 로고    scopus 로고
    • Acyl-homoserine lactone quorum sensing: from evolution to application
    • Schuster M., et al. Acyl-homoserine lactone quorum sensing: from evolution to application. Annu. Rev. Microbiol. 2013, 67:43-63.
    • (2013) Annu. Rev. Microbiol. , vol.67 , pp. 43-63
    • Schuster, M.1
  • 21
    • 84878758612 scopus 로고    scopus 로고
    • A metagenomic study highlights phylogenetic proximity of quorum-quenching and xenobiotic-degrading amidases of the AS-family
    • Tannières M., et al. A metagenomic study highlights phylogenetic proximity of quorum-quenching and xenobiotic-degrading amidases of the AS-family. PLoS ONE 2013, 8:e65473.
    • (2013) PLoS ONE , vol.8 , pp. e65473
    • Tannières, M.1
  • 22
    • 84894263511 scopus 로고    scopus 로고
    • Cooperation, quorum sensing, and evolution of virulence in Staphylococcus aureus
    • Pollitt E.J., et al. Cooperation, quorum sensing, and evolution of virulence in Staphylococcus aureus. Infect. Immun. 2014, 82:1045-1051.
    • (2014) Infect. Immun. , vol.82 , pp. 1045-1051
    • Pollitt, E.J.1
  • 23
    • 84869508724 scopus 로고    scopus 로고
    • Quorum sensing and the confusion about diffusion
    • West S.A., et al. Quorum sensing and the confusion about diffusion. Trends Microbiol. 2012, 20:586-594.
    • (2012) Trends Microbiol. , vol.20 , pp. 586-594
    • West, S.A.1
  • 24
    • 84896496605 scopus 로고    scopus 로고
    • Combinatorial quorum sensing allows bacteria to resolve their social and physical environment
    • Cornforth D.M., et al. Combinatorial quorum sensing allows bacteria to resolve their social and physical environment. Proc. Natl. Acad. Sci. U.S.A. 2014, 111:4280-4284.
    • (2014) Proc. Natl. Acad. Sci. U.S.A. , vol.111 , pp. 4280-4284
    • Cornforth, D.M.1
  • 25
    • 84875249804 scopus 로고    scopus 로고
    • A novel widespread interkingdom signaling circuit
    • González J.F., Venturi V. A novel widespread interkingdom signaling circuit. Trends Plant Sci. 2013, 18:167-174.
    • (2013) Trends Plant Sci. , vol.18 , pp. 167-174
    • González, J.F.1    Venturi, V.2
  • 26
    • 0028830908 scopus 로고
    • Bioactive cyclic dipeptides
    • Prasad C. Bioactive cyclic dipeptides. Peptides 1995, 16:151-164.
    • (1995) Peptides , vol.16 , pp. 151-164
    • Prasad, C.1
  • 27
    • 49749087240 scopus 로고    scopus 로고
    • Focus on cyclo(His-Pro): history and perspectives as antioxidant peptide
    • Minelli A., et al. Focus on cyclo(His-Pro): history and perspectives as antioxidant peptide. Amino Acids 2008, 35:283-289.
    • (2008) Amino Acids , vol.35 , pp. 283-289
    • Minelli, A.1
  • 28
    • 84855845980 scopus 로고    scopus 로고
    • 2,5-Diketopiperazines as neuroprotective agents
    • Cornacchia C., et al. 2,5-Diketopiperazines as neuroprotective agents. Mini Rev. Med. Chem. 2012, 12:2-12.
    • (2012) Mini Rev. Med. Chem. , vol.12 , pp. 2-12
    • Cornacchia, C.1
  • 29
    • 77958174291 scopus 로고    scopus 로고
    • Biosynthesis: a new (old) way of hijacking tRNA
    • Lahoud G., Hou Y.M. Biosynthesis: a new (old) way of hijacking tRNA. Nat. Chem. Biol. 2010, 6:795-796.
    • (2010) Nat. Chem. Biol. , vol.6 , pp. 795-796
    • Lahoud, G.1    Hou, Y.M.2
  • 30
    • 0022359330 scopus 로고
    • Synthesis, characterization, and anorectic testing of the four stereoisomers of cyclo(histidylproline)
    • Kukla M.J., et al. Synthesis, characterization, and anorectic testing of the four stereoisomers of cyclo(histidylproline). J. Med. Chem. 1985, 28:1745-1747.
    • (1985) J. Med. Chem. , vol.28 , pp. 1745-1747
    • Kukla, M.J.1
  • 31
    • 84864182405 scopus 로고    scopus 로고
    • Intestinal permeability of cyclic peptides: common key backbone motifs identified
    • Beck J.G., et al. Intestinal permeability of cyclic peptides: common key backbone motifs identified. J. Am. Chem. Soc. 2012, 134:12125-12133.
    • (2012) J. Am. Chem. Soc. , vol.134 , pp. 12125-12133
    • Beck, J.G.1
  • 32
    • 34748829955 scopus 로고    scopus 로고
    • Diketopiperazines as a tool for the study of transport across the blood-brain barrier (BBB) and their potential use as BBB-shuttles
    • Teixidó M., et al. Diketopiperazines as a tool for the study of transport across the blood-brain barrier (BBB) and their potential use as BBB-shuttles. J. Am. Chem. Soc. 2007, 129:11802-11813.
    • (2007) J. Am. Chem. Soc. , vol.129 , pp. 11802-11813
    • Teixidó, M.1
  • 33
    • 84863735130 scopus 로고    scopus 로고
    • Antimicrobial and biofilm inhibiting diketopiperazines
    • de Carvalho M.P., Abraham W.R. Antimicrobial and biofilm inhibiting diketopiperazines. Curr. Med. Chem. 2012, 19:3564-3577.
    • (2012) Curr. Med. Chem. , vol.19 , pp. 3564-3577
    • de Carvalho, M.P.1    Abraham, W.R.2
  • 34
    • 84865081172 scopus 로고    scopus 로고
    • 2,5-Diketopiperazines: synthesis, reactions, medicinal chemistry, and bioactive natural products
    • Borthwick A.D. 2,5-Diketopiperazines: synthesis, reactions, medicinal chemistry, and bioactive natural products. Chem. Rev. 2012, 112:3641-3716.
    • (2012) Chem. Rev. , vol.112 , pp. 3641-3716
    • Borthwick, A.D.1
  • 35
    • 84889872481 scopus 로고    scopus 로고
    • Identification and characterization of extracellular cyclic dipeptides as quorum-sensing signal molecules from Shewanella baltica, the specific spoilage organism of Pseudosciaena crocea during 4°C storage
    • Gu Q., et al. Identification and characterization of extracellular cyclic dipeptides as quorum-sensing signal molecules from Shewanella baltica, the specific spoilage organism of Pseudosciaena crocea during 4°C storage. J. Agric. Food Chem. 2013, 61:11645-11652.
    • (2013) J. Agric. Food Chem. , vol.61 , pp. 11645-11652
    • Gu, Q.1
  • 36
    • 33644857449 scopus 로고    scopus 로고
    • Cyclo(Phe-Pro) modulates the expression of ompU in Vibrio spp
    • Park D.K., et al. Cyclo(Phe-Pro) modulates the expression of ompU in Vibrio spp. J. Bacteriol. 2006, 188:2214-2221.
    • (2006) J. Bacteriol. , vol.188 , pp. 2214-2221
    • Park, D.K.1
  • 37
    • 84901708619 scopus 로고    scopus 로고
    • Cyclo(valine-valine) inhibits Vibrio cholerae virulence gene expression
    • Vikram A., et al. Cyclo(valine-valine) inhibits Vibrio cholerae virulence gene expression. Microbiology 2014, 160:1054-1062.
    • (2014) Microbiology , vol.160 , pp. 1054-1062
    • Vikram, A.1
  • 38
    • 84872334501 scopus 로고    scopus 로고
    • Dipeptide cis-cyclo(leucyl-tyrosyl) produced by sponge associated Penicillium sp. F37 inhibits biofilm formation of the pathogenic Staphylococcus epidermidis
    • Scopel M., et al. Dipeptide cis-cyclo(leucyl-tyrosyl) produced by sponge associated Penicillium sp. F37 inhibits biofilm formation of the pathogenic Staphylococcus epidermidis. Bioorg. Med. Chem. Lett. 2013, 23:624-626.
    • (2013) Bioorg. Med. Chem. Lett. , vol.23 , pp. 624-626
    • Scopel, M.1
  • 39
    • 38349111997 scopus 로고    scopus 로고
    • Biofilms in chronic wounds
    • James G.A., et al. Biofilms in chronic wounds. Wound Repair Regen. 2008, 16:37-44.
    • (2008) Wound Repair Regen. , vol.16 , pp. 37-44
    • James, G.A.1
  • 40
    • 84863770819 scopus 로고    scopus 로고
    • Phevalin (aureusimine B) production by Staphylococcus aureus biofilm and impacts on human keratinocyte gene expression
    • Secor P.R., et al. Phevalin (aureusimine B) production by Staphylococcus aureus biofilm and impacts on human keratinocyte gene expression. PLoS ONE 2012, 7:e40973.
    • (2012) PLoS ONE , vol.7 , pp. e40973
    • Secor, P.R.1
  • 42
    • 85027945471 scopus 로고    scopus 로고
    • Microbiota and neurodevelopmental windows: implications for brain disorders
    • Borre Y.E., et al. Microbiota and neurodevelopmental windows: implications for brain disorders. Trends Mol. Med. 2014, 20:509-518.
    • (2014) Trends Mol. Med. , vol.20 , pp. 509-518
    • Borre, Y.E.1
  • 43
    • 84904337496 scopus 로고    scopus 로고
    • The microbiota-gut-brain axis in gastrointestinal disorders: stressed bugs, stressed brain or both?
    • De Palma G., et al. The microbiota-gut-brain axis in gastrointestinal disorders: stressed bugs, stressed brain or both?. J. Physiol. 2014, 592:2989-2997.
    • (2014) J. Physiol. , vol.592 , pp. 2989-2997
    • De Palma, G.1
  • 44
    • 84938379194 scopus 로고    scopus 로고
    • Neuropeptides and the microbiota-gut-brain axis
    • Holzer P., Farzi A. Neuropeptides and the microbiota-gut-brain axis. Adv. Exp. Med. Biol. 2014, 817:195-219.
    • (2014) Adv. Exp. Med. Biol. , vol.817 , pp. 195-219
    • Holzer, P.1    Farzi, A.2
  • 45
    • 84905860693 scopus 로고    scopus 로고
    • Intestinal antigen-presenting cells in mucosal immune homeostasis: crosstalk between dendritic cells, macrophages and B-cells
    • Mann E.R., Li X. Intestinal antigen-presenting cells in mucosal immune homeostasis: crosstalk between dendritic cells, macrophages and B-cells. World J. Gastroenterol. 2014, 20:9653-9664.
    • (2014) World J. Gastroenterol. , vol.20 , pp. 9653-9664
    • Mann, E.R.1    Li, X.2
  • 46
    • 84906934110 scopus 로고    scopus 로고
    • Neuroimmune regulation of microglial activity involved in neuroinflammation and neurodegenerative diseases
    • González H., et al. Neuroimmune regulation of microglial activity involved in neuroinflammation and neurodegenerative diseases. J. Neuroimmunol. 2014, 274:1-13.
    • (2014) J. Neuroimmunol. , vol.274 , pp. 1-13
    • González, H.1
  • 47
    • 78649328152 scopus 로고    scopus 로고
    • Regional and subcellular localization of cycloprolylglycine in rat brain
    • Boiko S.S., et al. Regional and subcellular localization of cycloprolylglycine in rat brain. Bull. Exp. Biol. Med. 2010, 149:709-711.
    • (2010) Bull. Exp. Biol. Med. , vol.149 , pp. 709-711
    • Boiko, S.S.1
  • 48
    • 84898648573 scopus 로고    scopus 로고
    • SLC22, SLC44, and SLC47 transporters - organic anion and cation transporters: molecular and cellular properties
    • Pelis R.M., Wright S.H. SLC22, SLC44, and SLC47 transporters - organic anion and cation transporters: molecular and cellular properties. Curr. Top. Membr. 2014, 73:233-261.
    • (2014) Curr. Top. Membr. , vol.73 , pp. 233-261
    • Pelis, R.M.1    Wright, S.H.2
  • 49
    • 34548030734 scopus 로고    scopus 로고
    • Identification of the endogenous key substrates of the human organic cation transporter OCT2 and their implication in function of dopaminergic neurons
    • Taubert D., et al. Identification of the endogenous key substrates of the human organic cation transporter OCT2 and their implication in function of dopaminergic neurons. PLoS ONE 2007, 2:e385.
    • (2007) PLoS ONE , vol.2 , pp. e385
    • Taubert, D.1
  • 50
    • 84875181483 scopus 로고    scopus 로고
    • The SLC22 family with transporters of organic cations, anions and zwitterions
    • Koepsell H. The SLC22 family with transporters of organic cations, anions and zwitterions. Mol. Aspects Med. 2013, 34:413-435.
    • (2013) Mol. Aspects Med. , vol.34 , pp. 413-435
    • Koepsell, H.1
  • 51
    • 77955427864 scopus 로고    scopus 로고
    • Systemic administration of lipopolysaccharide induces cyclooxygenase-2 immunoreactivity in endothelium and increases microglia in the mouse hippocampus
    • Chung D.W., et al. Systemic administration of lipopolysaccharide induces cyclooxygenase-2 immunoreactivity in endothelium and increases microglia in the mouse hippocampus. Cell. Mol. Neurobiol. 2010, 30:531-541.
    • (2010) Cell. Mol. Neurobiol. , vol.30 , pp. 531-541
    • Chung, D.W.1
  • 52
    • 77950618226 scopus 로고    scopus 로고
    • Molecular mechanisms of the LPS-induced non-apoptotic ER stress-CHOP pathway
    • Nakayama Y., et al. Molecular mechanisms of the LPS-induced non-apoptotic ER stress-CHOP pathway. J. Biochem. 2010, 147:471-483.
    • (2010) J. Biochem. , vol.147 , pp. 471-483
    • Nakayama, Y.1
  • 53
    • 77950343252 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress and the inflammatory basis of metabolic disease
    • Hotamisligil G.S. Endoplasmic reticulum stress and the inflammatory basis of metabolic disease. Cell 2010, 140:900-917.
    • (2010) Cell , vol.140 , pp. 900-917
    • Hotamisligil, G.S.1
  • 54
    • 84899978839 scopus 로고    scopus 로고
    • Neuroinflammation and endoplasmic reticulum stress are coregulated by cyclo(His-Pro) to prevent LPS neurotoxicity
    • Bellezza I., et al. Neuroinflammation and endoplasmic reticulum stress are coregulated by cyclo(His-Pro) to prevent LPS neurotoxicity. Int. J. Biochem. Cell Biol. 2014, 51:159-169.
    • (2014) Int. J. Biochem. Cell Biol. , vol.51 , pp. 159-169
    • Bellezza, I.1
  • 55
    • 84869178487 scopus 로고    scopus 로고
    • Microglia and neurodegeneration: the role of systemic inflammation
    • Cunningham C. Microglia and neurodegeneration: the role of systemic inflammation. Glia 2013, 61:71-90.
    • (2013) Glia , vol.61 , pp. 71-90
    • Cunningham, C.1
  • 56
    • 79954504166 scopus 로고    scopus 로고
    • Basic principles and emerging concepts in the redox control of transcription factors
    • Brigelius-Flohe R., Flohé L. Basic principles and emerging concepts in the redox control of transcription factors. Antioxid. Redox Signal. 2011, 15:2335-2381.
    • (2011) Antioxid. Redox Signal. , vol.15 , pp. 2335-2381
    • Brigelius-Flohe, R.1    Flohé, L.2
  • 57
    • 79952271561 scopus 로고    scopus 로고
    • Nrf2 and NF-κB and their concerted modulation in cancer pathogenesis and progression
    • Bellezza I. Nrf2 and NF-κB and their concerted modulation in cancer pathogenesis and progression. Cancers (Basel) 2010, 2:483-497.
    • (2010) Cancers (Basel) , vol.2 , pp. 483-497
    • Bellezza, I.1
  • 58
    • 84869081486 scopus 로고    scopus 로고
    • Inhibition of NF-κB nuclear translocation via HO-1 activation underlies α-tocopheryl succinate toxicity
    • Bellezza I., et al. Inhibition of NF-κB nuclear translocation via HO-1 activation underlies α-tocopheryl succinate toxicity. J. Nutr. 2012, 23:1583-1591.
    • (2012) J. Nutr. , vol.23 , pp. 1583-1591
    • Bellezza, I.1
  • 59
    • 84873856533 scopus 로고    scopus 로고
    • Furanodien-6-one from Commiphora erythraea inhibits the NF-κB signalling and attenuates LPS-induced neuroinflammation
    • Bellezza I., et al. Furanodien-6-one from Commiphora erythraea inhibits the NF-κB signalling and attenuates LPS-induced neuroinflammation. Mol. Immunol. 2013, 54:347-354.
    • (2013) Mol. Immunol. , vol.54 , pp. 347-354
    • Bellezza, I.1
  • 60
    • 84882742544 scopus 로고    scopus 로고
    • Potential therapeutic effects of the simultaneous targeting of the Nrf2 and NF-κB pathways in diabetic neuropathy
    • Ganesh Yerra V., et al. Potential therapeutic effects of the simultaneous targeting of the Nrf2 and NF-κB pathways in diabetic neuropathy. Redox Biol. 2013, 1:394-397.
    • (2013) Redox Biol. , vol.1 , pp. 394-397
    • Ganesh Yerra, V.1
  • 61
    • 84901716846 scopus 로고    scopus 로고
    • Transcription factors NRF2 and NF-κB are coordinated effectors of the Rho family, GTP-binding protein RAC1 during inflammation
    • Cuadrado A., et al. Transcription factors NRF2 and NF-κB are coordinated effectors of the Rho family, GTP-binding protein RAC1 during inflammation. J. Biol. Chem. 2014, 289:15244-15258.
    • (2014) J. Biol. Chem. , vol.289 , pp. 15244-15258
    • Cuadrado, A.1
  • 62
    • 84901502561 scopus 로고    scopus 로고
    • Inflammation: regulating ROS
    • Leavy O. Inflammation: regulating ROS. Nat. Rev. Immunol. 2014, 14:357.
    • (2014) Nat. Rev. Immunol. , vol.14 , pp. 357
    • Leavy, O.1
  • 63
    • 70350133783 scopus 로고    scopus 로고
    • Cyclo(His-Pro) up-regulates heme oxygenase 1 via activation of Nrf2-ARE signalling
    • Minelli A., et al. Cyclo(His-Pro) up-regulates heme oxygenase 1 via activation of Nrf2-ARE signalling. J. Neurochem. 2009, 111:956-966.
    • (2009) J. Neurochem. , vol.111 , pp. 956-966
    • Minelli, A.1
  • 64
    • 84893116938 scopus 로고    scopus 로고
    • Heme oxygenase-1 as a target for drug discovery
    • Motterlini R., Foresti R. Heme oxygenase-1 as a target for drug discovery. Antioxid. Redox Signal. 2014, 20:1810-1826.
    • (2014) Antioxid. Redox Signal. , vol.20 , pp. 1810-1826
    • Motterlini, R.1    Foresti, R.2
  • 65
    • 84884950378 scopus 로고    scopus 로고
    • The complex interplay of iron metabolism, reactive oxygen species, and reactive nitrogen species: insights into the potential of various iron therapies to induce oxidative and nitrosative stress
    • Koskenkorva-Frank T.S., et al. The complex interplay of iron metabolism, reactive oxygen species, and reactive nitrogen species: insights into the potential of various iron therapies to induce oxidative and nitrosative stress. Free Radic. Biol. Med. 2013, 65:1174-1194.
    • (2013) Free Radic. Biol. Med. , vol.65 , pp. 1174-1194
    • Koskenkorva-Frank, T.S.1
  • 66
    • 27344458546 scopus 로고    scopus 로고
    • Activation of microglial NADPH oxidase is synergistic with glial iNOS expression in inducing neuronal death: a dual-key mechanism of inflammatory neurodegeneration
    • Mander P., Brown G.C. Activation of microglial NADPH oxidase is synergistic with glial iNOS expression in inducing neuronal death: a dual-key mechanism of inflammatory neurodegeneration. J. Neuroinflammation 2005, 2:20.
    • (2005) J. Neuroinflammation , vol.2 , pp. 20
    • Mander, P.1    Brown, G.C.2
  • 67
    • 84857235706 scopus 로고    scopus 로고
    • Cyclo(His-Pro) exerts anti-inflammatory effects by modulating NF-κB and Nrf2 signalling
    • Minelli A., et al. Cyclo(His-Pro) exerts anti-inflammatory effects by modulating NF-κB and Nrf2 signalling. Int. J. Biochem. Cell Biol. 2012, 44:525-535.
    • (2012) Int. J. Biochem. Cell Biol. , vol.44 , pp. 525-535
    • Minelli, A.1
  • 68
    • 55949136575 scopus 로고    scopus 로고
    • Interaction among heme oxygenase, nuclear factor-kappaB, and transcription activating factors in cardiac hypertrophy in hypertension
    • Jadhav A., et al. Interaction among heme oxygenase, nuclear factor-kappaB, and transcription activating factors in cardiac hypertrophy in hypertension. Hypertension 2008, 52:910-917.
    • (2008) Hypertension , vol.52 , pp. 910-917
    • Jadhav, A.1
  • 69
    • 84897147138 scopus 로고    scopus 로고
    • Inhibition of inducible nitric oxide synthase and interleukin-1(expression by tunicamycin in cultured glial cells exposed to lipopolysaccharide
    • Hosoi T., et al. Inhibition of inducible nitric oxide synthase and interleukin-1(expression by tunicamycin in cultured glial cells exposed to lipopolysaccharide. Brain Res. 2014, 1558:11-17.
    • (2014) Brain Res. , vol.1558 , pp. 11-17
    • Hosoi, T.1
  • 70
    • 84898071827 scopus 로고    scopus 로고
    • Toll-like receptor 4-mediated endoplasmic reticulum stress in intestinal crypts induces necrotizing enterocolitis
    • Afrazi A., et al. Toll-like receptor 4-mediated endoplasmic reticulum stress in intestinal crypts induces necrotizing enterocolitis. J. Biol. Chem. 2014, 289:9584-9599.
    • (2014) J. Biol. Chem. , vol.289 , pp. 9584-9599
    • Afrazi, A.1
  • 71
    • 84868130018 scopus 로고    scopus 로고
    • ER stress activates NF-κB by integrating functions of basal IKK activity, IRE1 and PERK
    • Tam A.B., et al. ER stress activates NF-κB by integrating functions of basal IKK activity, IRE1 and PERK. PLoS ONE 2012, 7:e45078.
    • (2012) PLoS ONE , vol.7 , pp. e45078
    • Tam, A.B.1
  • 72
    • 67649868135 scopus 로고    scopus 로고
    • Cyclo(His-Pro) promotes cytoprotection by activating Nrf2-mediated up-regulation of antioxidant defence
    • Minelli A., et al. Cyclo(His-Pro) promotes cytoprotection by activating Nrf2-mediated up-regulation of antioxidant defence. J. Cell. Mol. Med. 2009, 13:1149-1161.
    • (2009) J. Cell. Mol. Med. , vol.13 , pp. 1149-1161
    • Minelli, A.1
  • 73
    • 30344436372 scopus 로고    scopus 로고
    • Phosphoproteomic analysis of the effect of cyclo-[His-Pro] dipeptide on PC12 cells
    • Minelli A., et al. Phosphoproteomic analysis of the effect of cyclo-[His-Pro] dipeptide on PC12 cells. Peptides 2006, 27:105-113.
    • (2006) Peptides , vol.27 , pp. 105-113
    • Minelli, A.1
  • 75
    • 84896738387 scopus 로고    scopus 로고
    • Neuroinflammation: the role and consequences
    • Lyman M., et al. Neuroinflammation: the role and consequences. Neurosci. Res. 2014, 79:1-12.
    • (2014) Neurosci. Res. , vol.79 , pp. 1-12
    • Lyman, M.1
  • 76
    • 84887168548 scopus 로고    scopus 로고
    • Enzymatical and microbial degradation of cyclic dipeptides (diketopiperazines)
    • Perzborn M., et al. Enzymatical and microbial degradation of cyclic dipeptides (diketopiperazines). AMB Express 2013, 3:51.
    • (2013) AMB Express , vol.3 , pp. 51
    • Perzborn, M.1
  • 77
    • 84908119726 scopus 로고    scopus 로고
    • Metabolism and toxicity of high doses of cyclo(His-Pro) plus zinc in healthy human subjects
    • Uyemura K., et al. Metabolism and toxicity of high doses of cyclo(His-Pro) plus zinc in healthy human subjects. J. Drug Metab. Toxicol. 2010, 1:105.
    • (2010) J. Drug Metab. Toxicol. , vol.1 , pp. 105
    • Uyemura, K.1
  • 78
    • 84881414930 scopus 로고    scopus 로고
    • Phenylalanine-containing cyclic dipeptides - the lowest molecular weight hydrogelators based on unmodified proteinogenic amino acids
    • Kleinsmann A.J., Nachtsheim B.J. Phenylalanine-containing cyclic dipeptides - the lowest molecular weight hydrogelators based on unmodified proteinogenic amino acids. Chem. Commun. (Camb.) 2013, 49:7818-7820.
    • (2013) Chem. Commun. (Camb.) , vol.49 , pp. 7818-7820
    • Kleinsmann, A.J.1    Nachtsheim, B.J.2


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